Skip Nav Destination
First Edition
Research Article January 10 2025
Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of Diffuse Large B-cell Lymphoma
Camiel Göbel,Rachele Niccolai,Marnix Hugo Philip de Groot,Jayashree Jayachandran,Joleen Traets,Daan Juri Kloosterman,Sebastian Gregoricchio,Ben Morris,Maaike Kreft,Ji-Ying Song,Leyla Azarang,Eirini Kasa,Nienke Oskam,Daniel de Groot,Liesbeth Hoekman,Onno Bleijerveld,Marie José Kersten,Muhammad Assad Aslam,Fred van Leeuwen,Heinz Jacobs
Research Article January 10 2025
High-throughput drug screening identifies SMAC mimetics as enhancers of NK cell cytotoxicity in chronic myeloid leukemia
Petra Johanna Nygren,Jonas Otto Vilhelm Bouhlal,Emmi Jokinen,Sofia Forstén,Essi Laajala,Diogo Artur Alves Dias,Shady Adnan Awad,Aleksandr Ianevski,Jay Klievink,Hanna Lähteenmäki,Heikki Kuusanmäki,Mikko Myllymäki,Tiina Kasanen,Khalid Saeed,Dean A Lee,iCAN Flagship,Henrik Hjorth-Hansen,Tero Aittokallio,Olli Dufva,Satu Mustjoki
Research Article January 10 2025
Donor Regulatory T-Cell Therapy to Prevent Graft-Versus-Host Disease
Everett Meyer,Anna Pavlova,Alejandro Villar-Prados,Cameron S Bader,Bryan Xie,Lori Muffly,Paige Kim,Katherine C. Sutherland,Sushma Bharadwaj,Saurabh Dahiya,Matthew J Frank,Sally Arai,Laura Johnston,David B Miklos,Andrew R. Rezvani,Parveen Shiraz,Surbhi Sidana,Judith A. Shizuru,Wen-Kai Weng,Vaibhav Agrawal,Amy Putnam,Nathanial B Fernhoff,John Tamaresis,Ying Lu,Rahul D Pawar,J Scott McClellan,Robert Lowsky,Robert S. Negrin
Research Article January 10 2025
Epcoritamab plus GemOx in transplant-ineligible relapsed/refractory DLBCL: results from the EPCORE NHL-2 trial
Discussion January 8 2025
Introduction to a review series on reflections on a quarter century of TKIs in CML
Research Article January 7 2025
Potentiating CD20 monoclonal antibody therapy by targeting complement C3 fragment covalently deposited on lymphoma cells
Sivasubramanian Baskar,Haiyong Peng,Erika M Gaglione,Elizabeth J Carstens,Margaret A Lindorfer,Inhye E. Ahn,Sarah E.M. Herman,Martin Skarzynski,Jing Chang,Keyvan Keyvanfar,Vicent Butera,Amy Z Blackburn,Berengere Vire,Irina Maric,Maryalice Stetler-Stevenson,Constance M Yuan,Michael A Eckhaus,Susan Soto,Mohammed Z.H. Farooqui,Ronald P Taylor,Christoph Rader,Adrian Wiestner
Research Article January 7 2025
Selenoprotein-Mediated Redox Regulation Shapes the Cell Fate of HSCs and Mature Lineages
Yumi Aoyama,Hiromi Yamazaki,Koutarou Nishimua,Masaki Nomura,Tsukasa Shigehiro,Takafumi Suzuki,Weijia Zang,Yota Tatara,Hiromi Ito,Yasutaka Hayashi,Yui Koike,Miki Fukumoto,Atsushi Tanaka,Yifan Zhang,Wataru Saika,Chihiro Hasegawa,Shuya Kasai,Yingyi Kong,Yohei Minakuchi,Ken Itoh, Professor,Masayuki Yamamoto,Shinya Toyokuni,Atsushi Toyoda,Tomokatsu Ikawa,Akifumi Takaori-Kondo,Daichi Inoue
Research Article January 7 2025
Measurable residual disease and posttransplantation gilteritinib maintenance for patients with FLT3-ITD-mutated AML
Mark J. Levis,Mehdi Hamadani,Brent R. Logan,Richard J. Jones,Anurag K Singh,Mark R Litzow,John R. Wingard,Esperanza B. Papadopoulos,Alexander E. Perl,Robert J. Soiffer,Celalettin Ustun,Masumi Ueda Oshima,Geoffrey L Uy,Edmund K. Waller,Sumithira Vasu,Melhem M Solh,Asmita Mishra,Lori Muffly,Hee-Je Kim,Matthias Stelljes,Yuho Najima,Masahiro Onozawa,Kirsty J Thomson,Arnon Nagler,Andrew H Wei,Guido Marcucci,Caroline Chen,Nahla Hasabou,Matt Rosales,Jason E. Hill,Stanley C. Gill,Rishita Nuthethi,Denise King,Adam M Mendizabal,Steven M. Devine,Mary M Horowitz,Yi-Bin Chen
Research Article January 7 2025
Targeting Senescent Stemlike Subpopulations in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia
Yang-Yang Ding,Jonathan H Sussman,Kellyn Madden,Joseph P Loftus,Robert K Chen,Catherine D Falkenstein,Diego Alberto Barcenas Lopez,David A Hottman,Benjamin Mathier,Wenbao Yu,Jason Xu,Changya Chen,Chia-Hui Chen,Bing He,Shovik Bandyopadhyay,Zhan Zhang,DongGeun Lee,Hong Wang,Junmin Peng,Chi V Dang,Kai Tan,Sarah K Tasian
Research Article January 6 2025
Glucarpidase for Treatment of High-Dose Methotrexate Toxicity
Shruti Gupta,Sarah Allison Kaunfer,Kevin L Chen,Julie-Alexia Dias,Anitha Vijayan,Arun Rajasekaran,Jason Prosek,Huong L. Truong,Anthony Wood,Claude Bassil,Amanda DeMauro Renaghan,Chintan V Shah,Jingjing Zhang,Ilya Glezerman,Christopher Carlos,Katherine Kelly,Christopher J Passero,Jan Drappatz,Ala Abudayyeh,Daniel Shin,C. John Sperati,Bradley J Yelvington,Swetha Rani Kanduri,Javier A Neyra,Daniel Edmonston,Anushree C Shirali,Anip Bansal,Abdallah Geara,Zain Mithani,Susan L Ziolkowski,Arash Rashidi,Jonathan Jakubowski,Ashwini Pujari,David A Bond,Emily K Dotson,Sarah A Wall,John T. Patton,Jason N Barreto,Sandra M Hermann,Mohammad Salman Sheikh,Rachid C Baz,Jae Hui Lee,Nicholas Lucchesi,Michael Kolman,Muhammad Ahsan Rasheed,Afsheen Afzal,Dasol Kang,Amrita Mahesh,Raymond Hsu,Anthony Nicolaysen,Kibrewessen Tefera,Claire Schretlen,Ryan M Miller,Juan Carlos Q Velez,Alexander H Flannery,Abinet M Aklilu,Shuchi Anand,Soniya Chandrasekhara,Vicki Donley,Ashka Patel,Jian Ni,Shobana Krishnamurthy,Rafia Ali,Osman A Yilmam,Sophia L Wells,Jessica L Ortega,Olivia L Green-Lingren,Rebecca Karp Leaf,Meghan E Sise,Lakshmi Nayak,Ann S. LaCasce,Nelson Leung,David E Leaf
Review Article January 6 2025
The Evolution of Treatment-Free Remission
Review Article December 30 2024
High-Risk MCL: Recognition and Treatment
Review Article December 30 2024
Genetic subtypes of B-cell acute lymphoblastic leukemia in adults
Review Article December 30 2024
How I Diagnose and Treat Acute Infection-associated Purpura Fulminans
Research Article December 30 2024
Targeting Enterobacter cloacae attenuates osteolysis by reducing ammonium in multiple myeloma
Review Article December 30 2024
How I Manage Patients with Unexplained Cytopenia
Research Article December 30 2024
Prognostic and therapeutic implications of measurable residual disease levels during remission induction of childhood ALL
Weina Zhang,Jiaoyang Cai,Xiang Wang,Yani Ma,Xiaofan Zhu,Jie Yu,Peifang Xiao,Ju Gao,Yongjun Fang,Changda Liang,Xue Li,Fen Zhou,Xiaowen Zhai,Xiaoxiao Xu,Xin Tian,Aiguo Liu,Ningling Wang,Jiashi Zhu,Lingzhen Wang,Frankie Wai Tsoi Cheng,Liangchun Yang,Ge Zhang,Cheng Cheng,Jun J. Yang,Shuhong Shen,Chi-kong Li,Benshang Li,Hua Jiang,Ching-Hon Pui
Review Article December 30 2024
FDA-approved therapies for chronic GVHD
Research Article December 30 2024
Odronextamab monotherapy in R/R DLBCL after progression with CAR T-cell therapy: Primary analysis of the ELM-1 study
Research Article December 27 2024
α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia
Scott Evan Millman,Almudena Chaves-Perez,Sudha Janaki-Raman,Yu-Jui Ho,John P Morris IV,Varun Narendra,Chi-Chao Chen,Benjamin T Jackson,Jossie J Yashinskie,Riccardo Mezzadra,Tessa I Devine,Valentin J. A. Barthet,Michelle Saoi,Timour Baslan,Sha Tian,Zohar Sachs,Lydia WS Finley,Justin R Cross,Scott W Lowe
Research Article December 27 2024
Cullin-5 controls the number of megakaryocyte-committed stem cells to prevent thrombocytosis in mice
Research Article December 27 2024
DNTT-mediated DNA Damage Response Drives Inotuzumab Ozogamicin Resistance in B-cell Acute Lymphoblastic Leukemia
Carolin S. Escherich,Takaya Moriyama,Zhenhua Li,YuChih Hsiao,Wenjian Yang,Yizhen Li,Noemi Reyes,Megan Walker,Amit Budhraja,Sheetal Bhatara,Ernesto Diaz-Flores,Wendy Stock,Elisabeth Paietta,Marina Y. Konopleva,Steven M Kornblau,Mark R Litzow,Hiroto Inaba,Ching-Hon Pui,Joseph T. Opferman,Mignon L. Loh,Jiyang Yu,Maureen O'Brien,William E. Evans,Jun J. Yang
Review Article December 27 2024
Novel Treatment Strategies for Chronic Myeloid Leukemia
Review Article December 24 2024
How I Treat AML relapse after allogeneic HCT
Review Article December 24 2024
Menin inhibitors in the treatment of acute myeloid leukemia
Letter December 24 2024
Non-V600E BRAF mutations and treatment for Hairy Cell Leukemia
Research Article December 19 2024
Long-Term Efficacy and Safety of Danicopan as Add-On Therapy to Ravulizumab or Eculizumab in PNH With Significant EVH
Brief Report December 19 2024
Approaching Hypercalcemia in Monoclonal Gammopathy of Undetermined Significance: Insights from the iStopMM study
Ástrún Helga Jónsdóttir,Helga Ágústa Sigurjónsdóttir, Prof.,Sigrun Thorsteinsdottir,Thorir Einarsson Long,Ingigerður Sólveig Sverrisdóttir,Elias Eythorsson,Jon Thorir Oskarsson,Runólfur Pálsson,Olafur Skuli Indridason,Bryjnar Vidarsson,Pall T Onundarson,Isleifur Olafsson,Ingunn Þorsteinsdóttir,Bjarni A Agnarsson,Margret Sigurdardottir,Asbjorn Jonsson,Malin L. Hultcrantz,Brian G.M. Durie,Stephen Harding,Carl Ola Landgren,Thorvardur Jon Love,Sigurdur Yngvi Kristinsson,Sæmundur Rögnvaldsson
Review Article December 19 2024
How I treat quantitative fibrinogen disorders
Research Article December 18 2024
Deficiency of neutrophil gelatinase-associated lipocalin elicits Hemophilia-like bleeding and clotting disorder
Research Article December 18 2024
Mutations in AMBRA1 aggravate β-thalassemia by impairing autophagy-mediated clearance of free α-globin
Research Article December 18 2024
Oral Inflammation and Microbiome Dysbiosis Exacerbate Chronic Graft-versus-host Disease
Yui Kambara,Hideaki Fujiwara,Akira Yamamoto,Kazuyoshi Gotoh,Shuma Tsuji,Mari Kunihiro,Tadashi Oyama,Toshiki Terao,Ayame Sato,Takehiro Tanaka,Daniel Peltier,Keisuke Seike,Hisakazu Nishimori,Noboru Asada,Daisuke Ennishi,Keiko Fujii,Nobuharu Fujii,Ken-ichi Matsuoka,Yoshihiko Soga,Pavan Reddy,Yoshinobu Maeda
Research Article December 18 2024
Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis
Research Article December 16 2024
DLBclass: A Probabilistic Molecular Classifier to Guide Clinical Investigation and Practice in DLBCL
Research Article December 11 2024
Single-cell epigenetic and clonal analysis decodes disease progression in pediatric acute myeloid leukemia
Research Article December 10 2024
Inflammation-driven NFκB signaling represses Ferroportin transcription in macrophages via HDAC 1 and 3
Research Article December 10 2024
IFN-I promotes T cell-independent immunity and RBC autoantibodies via modulation of B-1 cell subsets in murine SCD
Research Article December 10 2024
Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation
Fabien Boudia,Marie Baille,Loelia Babin,Zakia Aid,Elie Robert,Julie Riviere,Klaudia Galant,Verónica Alonso-Pérez,Laura Anselmi,Brahim Arkoun,Nassera Abermil,Christophe Marzac,Salvatore Nicola Bertuccio,Alexia Regnault de Premesnil,Cecile K. Lopez,Alexandre Eeckhoutte,Audrey Naimo,Betty Leite,Cyril Catelain,Christophe Metereau,Patrick Gonin,Nathalie Gaspar,Juerg Schwaller,Olivier A Bernard,Hana Raslova,Murielle Gaudry,Antonin Marchais,Hélène Lapillonne,Arnaud Petit,Francoise Pflumio,Marie-Laure Arcangeli,Erika Brunet,Thomas Mercher
Research Article December 9 2024
Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation
Viral Shah,George Giotopoulos,Hikari Osaki,Markus Meyerhöfer,Eshwar Meduri,Aaron Gallego-Crespo,Malte Andreas Behrendt,Maria Saura-Pañella,Aarti Tarkar,Benedict Schubert,Haiyang Yun,Sarah J. Horton,Shuchi Agrawal-Singh, Dr,Patricia S Hähnel,Faisal Basheer,Dave Lugo,Ioanna Eleftheriadou,Olena Barbash,Arindam Dhar,Michael Kühn,Borhane Guezguez,Matthias Theobald,Thomas Kindler,Paolo Gallipoli,Paul Sung-Hao Yeh,Mark A. Dawson,Rab K Prinjha,Brian JP Huntly,Daniel Sasca
Research Article December 9 2024
Tumor burden quantified by Soluble B-Cell Maturation Antigen and Metabolic Tumor Volume determine myeloma CAR-T outcomes
Ciara L Freeman,Jerald Noble,Meghan Menges,Ricardo Villanueva,Justyn Y Nakashima,Nicholas B Figura,R. Petter Tonseth,Dietrich Werner Idiaquez,Lawrence Skelson,Eric C Smith,Julieta Abraham-Miranda,Salvatore Corallo,Gabriel De Avila,Omar Castaneda Puglianini,Hien D Liu,Melissa Alsina,Taiga Nishihori,Kenneth H Shain,Rachid C Baz,Brandon J Blue,Ariel Grajales-Cruz,John M. Koomen,Reginald M Atkins,Doris K Hansen,Ariosto Siqueira Silva,Jongphil Kim,Yoganand Balagurunathan,Frederick L Locke
Research Article December 9 2024
Anti-CD19 antibody cotreatment enhances serial killing activity of anti-CD19 CAR-T/-NK cells and reduces trogocytosis
Research Article December 9 2024
The GATA-3-dependent transcriptome and tumor microenvironment are regulated by eIF4E and XPO1 in T-cell lymphomas
Nermin Kady,Suhaib Abdelrahman,Ahmar Rauf,Alyssa Burgess,Jonathan Weiss,Hirushi Gunasekara,Neal Thomas Ramseier,Ira P Maine,Alejandro Zevallos-Morales,Vanessa Perez-Silos,Ashley Wolfe,Alexandra Hristov,Noah A Brown,Kedar V Inamdar,Maria Sverdlov,Ying Samuel Hu,Carlos Murga-Zamalloa,Chenguang Wang,Ryan A Wilcox
Research Article December 9 2024
Efficacy and Safety of Venetoclax Plus Azacitidine for Patients With Treatment-Naive High-Risk Myelodysplastic Syndromes
Advertisement intended for health care professionals
Email alerts
Advertisement intended for health care professionals
