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Journal Articles

Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation

Blood blood.2025028933.

https://doi.org/10.1182/blood.2025028933

Published: 2025

Includes: Supplemental data

Journal Articles

FLT3-F691L confers kinase-independent resistance via Grb2-dependent MAPK signaling in AML

LaQuita Jones, Akhtar Khadaroo, Riya Tiwari, Kwangmin Choi, Mike Adam, Mark Wunderlich, Cody Stillwell, Christina Sexton, William Seibel, Greg Tawa, Scott Hoyt, Craig Thomas, Daniel Starczynowski

Blood (2025) 146 (Supplement 1): 5049.

https://doi.org/10.1182/blood-2025-5049

Published: 2025

Journal Articles

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

Blood (2025) 146 (Supplement 1): 2539.

https://doi.org/10.1182/blood-2025-2539

Published: 2025

Journal Articles

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Blood (2025) 146 (Supplement 1): 212.

https://doi.org/10.1182/blood-2025-212

Published: 2025

Journal Articles

Mitochondrial RNA pseudouridine reprograms metabolism and induces immunosuppression in myeloid leukemia

Blood (2025) 146 (Supplement 1): 211.

https://doi.org/10.1182/blood-2025-211

Published: 2025

Journal Articles

NEAT1-triggered collateral activity of CRISPR/Cas13 exhibits antileukemic activity

Ruka Shimura, Keita Yamamoto, Yu-Hsuan Chang, Ken Suzaki, Zongru Yang, Tomohiro Yabushita, Wenyu Zhang, Kohei Iida, Kaito Mimura, Kenichi Yoshida, Mark Wunderlich, Benjamin Mizukawa, Toshio Kitamura, Susumu Goyama

Blood (2025) 146 (Supplement 1): 1470.

https://doi.org/10.1182/blood-2025-1470

Published: 2025

Journal Articles

Chromatin remodeler SATB2 thorough Bmi1/PRC1 activity controls transformation and reprogramming of ph+ B-cell progenitors

Shakyrah Smith, Michael Kotliar, Mark Wunderlich, Ashley Wellendorf, Sarmistha Das, Benjamin Mizukawa, Artem Barski, Shesh Rai, Jose Cancelas, Ramesh Nayak

Blood (2025) 146 (Supplement 1): 5032.

https://doi.org/10.1182/blood-2025-5032

Published: 2025

Journal Articles

Single-Cell Multi-Omic Analysis of KMT2A -Rearranged Pediatric Acute Leukemia Clonal Evolution

Morgan Drucker, Dalia Dhingra, Mark Wunderlich, John Perentesis, Daniel Starczynowski, Robert L. Bowman, Linde A. Miles

Blood (2024) 144 (Supplement 1): 66.

https://doi.org/10.1182/blood-2024-202590

Published: 2024

Journal Articles

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Blood (2024) 144 (Supplement 1): 625.

https://doi.org/10.1182/blood-2024-201916

Published: 2024

Journal Articles

The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It

Sean Walulik, Sarai Dean, Eric J Vick, Xiaoqin Zhu, Mark Wunderlich, Chih-Hsing Chou, Kwangmin Choi, H. Leighton Grimes, Daniel T. Starczynowski, Linde A. Miles, Andrew Volk

Blood (2023) 142 (Supplement 1): 1410.

https://doi.org/10.1182/blood-2023-186180

Published: 2023

Journal Articles

Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML

Joshua Bennett, Chiharu Ishikawa, Puneet Agarwal, Jennifer Yeung, Avery Sampson, Emma Uible, Eric Vick, Lyndsey C. Bolanos, Kathleen Hueneman, Mark Wunderlich, Amal Kolt, Kwangmin Choi, Andrew Volk, Kenneth D. Greis, Jan Rosenbaum, Scott B. Hoyt, Craig J. Thomas, Daniel T. Starczynowski

Blood (2023) 142 (11): 989–1007.

https://doi.org/10.1182/blood.2022018718

Published: 2023

Includes: Supplemental data

Journal Articles

In Vivo Crispr Screening Identifies Novel Vulnerabilities in ETO2/GLIS2- rearranged Leukemia

Mark Wunderlich, Jason Clark, Jing Chen, Lynn Lee

Blood (2022) 140 (Supplement 1): 3431–3432.

https://doi.org/10.1182/blood-2022-169837

Published: 2022

Journal Articles

JMJD1C Interacts with the Ncor Corepressor Complex and Is Required for Human MLL-AF9 Leukemogenesis

Olivia Arnold, Luke Christiansen, Jesus Izaguirre-Carbonell, Theresa Bluemn, Mark Wunderlich, Nan Zhu

Blood (2022) 140 (Supplement 1): 8700–8701.

https://doi.org/10.1182/blood-2022-166806

Published: 2022

Journal Articles

TRIM13 Is a Novel Cell Cycle Hub Regulated By CHAF1B to Promote Acute Myeloid Leukemogenesis

Sarai Dean, Chiharu Ishikawa, Xiaoqin Zhu, Timothy Nixon, Sean Walulik, Michael Wyder, Jessica Jordan, Mark Wunderlich, Daniel T. Starczynowski, Nathan Salomonis, Ken Greis, Andrew Volk

Blood (2022) 140 (Supplement 1): 2978–2979.

https://doi.org/10.1182/blood-2022-169879

Published: 2022

Journal Articles

TET2-Mediated mRNA and DNA Oxidation in Leukemia Homing and Immune Evasion

Blood (2022) 140 (Supplement 1): 2975–2977.

https://doi.org/10.1182/blood-2022-162619

Published: 2022

Journal Articles

IRAK1 Contributes to IRAK4 Inhibitor Resistance Via Non-Canonical Signaling Mechanisms in MDS/AML

Josh Bennett, Jennifer Yeung, Avery Sampson, Kathleen Hueneman, Mark Wunderlich, Kwangmin Choi, Andrew Volk, Scott B. Hoyt, Craig J. Thomas, Daniel T. Starczynowski

Blood (2022) 140 (Supplement 1): 2240–2241.

https://doi.org/10.1182/blood-2022-167526

Published: 2022

Journal Articles

ASXL1 Mutations Are Associated with a Response to the Combination of Alvocidib and 5-Azacytidine in Higher-Risk Myelodysplastic Syndromes

Blood (2022) 140 (Supplement 1): 9749–9750.

https://doi.org/10.1182/blood-2022-165298

Published: 2022

Journal Articles

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken

Blood (2022) 140 (17): 1875–1890.

https://doi.org/10.1182/blood.2021015036

Published: 2022

Includes: Supplemental data

Journal Articles

Unleashing Cell-Intrinsic Inflammation As a Strategy to Kill AML Blasts

Jana M Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Maxim Pimkin, Linda Ross, Neekesh V Dharia, Amanda L Robinchaud, Amy Conway, Delan Khalid, Mark Wunderlich, Lina Benajiba, Behnam Nabet, Nathanael S Gray, Stuart H. Orkin, Kimberly Stegmaier

Blood (2021) 138 (Supplement 1): 3305.

https://doi.org/10.1182/blood-2021-151511

Published: 2021

Journal Articles

SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia

Shan Lin, Nastassja K. Scheidegger, Gabriela Alexe, Bo Kyung A. Seong, Neekesh V Dharia, Caroline Wechsler, Guillaume Kugener, Amanda L Robinchaud, Amy Conway, Biniam Adane, Scott Younger, Federica Piccioni, Lynn Lee, Mark Wunderlich, Kimberly Stegmaier

Blood (2021) 138 (Supplement 1): 3319.

https://doi.org/10.1182/blood-2021-152023

Published: 2021

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Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation

FLT3-F691L confers kinase-independent resistance via Grb2-dependent MAPK signaling in AML

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Mitochondrial RNA pseudouridine reprograms metabolism and induces immunosuppression in myeloid leukemia

NEAT1-triggered collateral activity of CRISPR/Cas13 exhibits antileukemic activity

Chromatin remodeler SATB2 thorough Bmi1/PRC1 activity controls transformation and reprogramming of ph+ B-cell progenitors

Single-Cell Multi-Omic Analysis of KMT2A -Rearranged Pediatric Acute Leukemia Clonal Evolution

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It

Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML

In Vivo Crispr Screening Identifies Novel Vulnerabilities in ETO2/GLIS2- rearranged Leukemia

JMJD1C Interacts with the Ncor Corepressor Complex and Is Required for Human MLL-AF9 Leukemogenesis

TRIM13 Is a Novel Cell Cycle Hub Regulated By CHAF1B to Promote Acute Myeloid Leukemogenesis

TET2-Mediated mRNA and DNA Oxidation in Leukemia Homing and Immune Evasion

IRAK1 Contributes to IRAK4 Inhibitor Resistance Via Non-Canonical Signaling Mechanisms in MDS/AML

ASXL1 Mutations Are Associated with a Response to the Combination of Alvocidib and 5-Azacytidine in Higher-Risk Myelodysplastic Syndromes

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Unleashing Cell-Intrinsic Inflammation As a Strategy to Kill AML Blasts

SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia

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