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Journal Articles

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Blood (2024) 144 (Supplement 1): 625.

https://doi.org/10.1182/blood-2024-201916

Published: 2024

Journal Articles

Single-Cell Multi-Omic Analysis of KMT2A -Rearranged Pediatric Acute Leukemia Clonal Evolution

Morgan Drucker, Dalia Dhingra, Mark Wunderlich, John Perentesis, Daniel Starczynowski, Robert L. Bowman, Linde A. Miles

Blood (2024) 144 (Supplement 1): 66.

https://doi.org/10.1182/blood-2024-202590

Published: 2024

Journal Articles

The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It

Sean Walulik, Sarai Dean, Eric J Vick, Xiaoqin Zhu, Mark Wunderlich, Chih-Hsing Chou, Kwangmin Choi, H. Leighton Grimes, Daniel T. Starczynowski, Linde A. Miles, Andrew Volk

Blood (2023) 142 (Supplement 1): 1410.

https://doi.org/10.1182/blood-2023-186180

Published: 2023

Journal Articles

Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML

Joshua Bennett, Chiharu Ishikawa, Puneet Agarwal, Jennifer Yeung, Avery Sampson, Emma Uible, Eric Vick, Lyndsey C. Bolanos, Kathleen Hueneman, Mark Wunderlich, Amal Kolt, Kwangmin Choi, Andrew Volk, Kenneth D. Greis, Jan Rosenbaum, Scott B. Hoyt, Craig J. Thomas, Daniel T. Starczynowski

Blood (2023) 142 (11): 989–1007.

https://doi.org/10.1182/blood.2022018718

Published: 2023

Includes: Supplemental data

Journal Articles

ASXL1 Mutations Are Associated with a Response to the Combination of Alvocidib and 5-Azacytidine in Higher-Risk Myelodysplastic Syndromes

Blood (2022) 140 (Supplement 1): 9749–9750.

https://doi.org/10.1182/blood-2022-165298

Published: 2022

Journal Articles

IRAK1 Contributes to IRAK4 Inhibitor Resistance Via Non-Canonical Signaling Mechanisms in MDS/AML

Josh Bennett, Jennifer Yeung, Avery Sampson, Kathleen Hueneman, Mark Wunderlich, Kwangmin Choi, Andrew Volk, Scott B. Hoyt, Craig J. Thomas, Daniel T. Starczynowski

Blood (2022) 140 (Supplement 1): 2240–2241.

https://doi.org/10.1182/blood-2022-167526

Published: 2022

Journal Articles

TRIM13 Is a Novel Cell Cycle Hub Regulated By CHAF1B to Promote Acute Myeloid Leukemogenesis

Sarai Dean, Chiharu Ishikawa, Xiaoqin Zhu, Timothy Nixon, Sean Walulik, Michael Wyder, Jessica Jordan, Mark Wunderlich, Daniel T. Starczynowski, Nathan Salomonis, Ken Greis, Andrew Volk

Blood (2022) 140 (Supplement 1): 2978–2979.

https://doi.org/10.1182/blood-2022-169879

Published: 2022

Journal Articles

TET2-Mediated mRNA and DNA Oxidation in Leukemia Homing and Immune Evasion

Blood (2022) 140 (Supplement 1): 2975–2977.

https://doi.org/10.1182/blood-2022-162619

Published: 2022

Journal Articles

In Vivo Crispr Screening Identifies Novel Vulnerabilities in ETO2/GLIS2- rearranged Leukemia

Mark Wunderlich, Jason Clark, Jing Chen, Lynn Lee

Blood (2022) 140 (Supplement 1): 3431–3432.

https://doi.org/10.1182/blood-2022-169837

Published: 2022

Journal Articles

JMJD1C Interacts with the Ncor Corepressor Complex and Is Required for Human MLL-AF9 Leukemogenesis

Olivia Arnold, Luke Christiansen, Jesus Izaguirre-Carbonell, Theresa Bluemn, Mark Wunderlich, Nan Zhu

Blood (2022) 140 (Supplement 1): 8700–8701.

https://doi.org/10.1182/blood-2022-166806

Published: 2022

Journal Articles

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V. Grinev, Anetta Ptasinska, Paulynn S. Chin, Claus Meyer, Sirintra Nakjang, Jayne Y. Hehir-Kwa, Daniel Williamson, Pierre Cauchy, Peter Keane, Salam A. Assi, Minoo Ashtiani, Sophie G. Kellaway, Maria R. Imperato, Fotini Vogiatzi, Elizabeth K. Schweighart, Shan Lin, Mark Wunderlich, Janine Stutterheim, Alexander Komkov, Elena Zerkalenkova, Paul Evans, Hesta McNeill, Alex Elder, Natalia Martinez-Soria, Sarah E. Fordham, Yuzhe Shi, Lisa J. Russell, Deepali Pal, Alex Smith, Zoya Kingsbury, Jennifer Becq, Cornelia Eckert, Oskar A. Haas, Peter Carey, Simon Bailey, Roderick Skinner, Natalia Miakova, Matthew Collin, Venetia Bigley, Muzlifah Haniffa, Rolf Marschalek, Christine J. Harrison, Catherine A. Cargo, Denis Schewe, Yulia Olshanskaya, Michael J. Thirman, Peter N. Cockerill, James C. Mulloy, Helen J. Blair, Josef Vormoor, James M. Allan, Constanze Bonifer, Olaf Heidenreich, Simon Bomken

Blood (2022) 140 (17): 1875–1890.

https://doi.org/10.1182/blood.2021015036

Published: 2022

Includes: Supplemental data

Journal Articles

An In Vivo CRISPR Screening Platform to Identify New Therapeutic Targets in AML

Shan Lin, Clement Larrue, Nastassja K. Scheidegger, Bo Kyung A. Seong, Neekesh V Dharia, Caroline Wechsler, Guillaume Kugener, Amanda L Robinchaud, Amy Conway, Biniam Adane, Scott Younger, Federica Piccioni, Lynn Lee, Mark Wunderlich, Jerome Tamburini, Kimberly Stegmaier

Blood (2021) 138 (Supplement 1): 266.

https://doi.org/10.1182/blood-2021-153039

Published: 2021

Journal Articles

Momelotinib Is a Highly Potent Inhibitor of FLT3-Mutant AML

Mohammad Azhar, Zachary Kincaid, Meenu Kesarwani, Mark Wunderlich, Tahir Latif, Daniel Starczynowski, Mohammad Azam

Blood (2021) 138 (Supplement 1): 206.

https://doi.org/10.1182/blood-2021-148822

Published: 2021

Journal Articles

Unleashing Cell-Intrinsic Inflammation As a Strategy to Kill AML Blasts

Jana M Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Maxim Pimkin, Linda Ross, Neekesh V Dharia, Amanda L Robinchaud, Amy Conway, Delan Khalid, Mark Wunderlich, Lina Benajiba, Behnam Nabet, Nathanael S Gray, Stuart H. Orkin, Kimberly Stegmaier

Blood (2021) 138 (Supplement 1): 3305.

https://doi.org/10.1182/blood-2021-151511

Published: 2021

Journal Articles

SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia

Shan Lin, Nastassja K. Scheidegger, Gabriela Alexe, Bo Kyung A. Seong, Neekesh V Dharia, Caroline Wechsler, Guillaume Kugener, Amanda L Robinchaud, Amy Conway, Biniam Adane, Scott Younger, Federica Piccioni, Lynn Lee, Mark Wunderlich, Kimberly Stegmaier

Blood (2021) 138 (Supplement 1): 3319.

https://doi.org/10.1182/blood-2021-152023

Published: 2021

Journal Articles

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Yusuke Tarumoto, Shan Lin, Jinhua Wang, Joseph P. Milazzo, Yali Xu, Bin Lu, Zhaolin Yang, Yiliang Wei, Sofya Polyanskaya, Mark Wunderlich, Nathanael S. Gray, Kimberly Stegmaier, Christopher R. Vakoc

Blood (2020) 135 (1): 56–70.

https://doi.org/10.1182/blood.2019001576

Published: 2020

Includes: Supplemental data

Journal Articles

The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Mark Wunderlich, MS, Benjamin Mizukawa, Xiang-ming Zha, PhD, Stephanie Halene, MD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 2661.

https://doi.org/10.1182/blood-2019-125455

Published: 2019

Journal Articles

The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph + (BCR-ABL1) B-ALL

Nicolas Nassar, PhD, Shailaja N Hegde, PhD, Anjelika Gasilina, Mark Wunderlich, MS, Gurdat Premnauth, Edward Merino, PhD, Yuan Lin, PhD, Reza Ahmadian, PhD, Yi Zheng, PhD, Benjamin Mizukawa, Lisa Privette Vinnedge, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 4647.

https://doi.org/10.1182/blood-2019-130250

Published: 2019

Journal Articles

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Blood (2019) 134 (Supplement_1): 233.

https://doi.org/10.1182/blood-2019-124535

Published: 2019

Journal Articles

Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement

Mark Wunderlich, MS, Jing Chen, Eric O'Brien, BSc, Nicole Manning, Christina Sexton, Luke Byerly, John P Perentesis, Benjamin Mizukawa, James C Mulloy

Blood (2019) 134 (Supplement_1): 3766.

https://doi.org/10.1182/blood-2019-129225

Published: 2019

NARROW

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Single-Cell Multi-Omic Analysis of KMT2A -Rearranged Pediatric Acute Leukemia Clonal Evolution

The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It

Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML

ASXL1 Mutations Are Associated with a Response to the Combination of Alvocidib and 5-Azacytidine in Higher-Risk Myelodysplastic Syndromes

IRAK1 Contributes to IRAK4 Inhibitor Resistance Via Non-Canonical Signaling Mechanisms in MDS/AML

TRIM13 Is a Novel Cell Cycle Hub Regulated By CHAF1B to Promote Acute Myeloid Leukemogenesis

TET2-Mediated mRNA and DNA Oxidation in Leukemia Homing and Immune Evasion

In Vivo Crispr Screening Identifies Novel Vulnerabilities in ETO2/GLIS2- rearranged Leukemia

JMJD1C Interacts with the Ncor Corepressor Complex and Is Required for Human MLL-AF9 Leukemogenesis

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

An In Vivo CRISPR Screening Platform to Identify New Therapeutic Targets in AML

Momelotinib Is a Highly Potent Inhibitor of FLT3-Mutant AML

Unleashing Cell-Intrinsic Inflammation As a Strategy to Kill AML Blasts

SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium

The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph + (BCR-ABL1) B-ALL

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement

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American Society of Hematology

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ASH Publications

American Society of Hematology

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