“Ordo ab Chao”: Out of Chaos, Order
May 2025
Elna Saah, MD, MS
Dr. Saah reflects on the Latin phrase “ordo ab chao,” or “order out of chaos,” and offers a thoughtful meditation on how this concept resonates within her life.
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May 2025
Editor's Corner
Venetoclax Plus Decitabine Shows Similar Efficacy to Intensive Chemotherapy as Front- Line Therapy for Young, Fit Patients With AML
May 2025
The combination of venetoclax plus decitabine is shown to be as effective and have a better safety profile when compared with the current chemotherapy-based standard of care of cytarabine plus an anthracycline in younger, fit patients with acute myeloid leukemia (AML).
PDMPs May Negatively Affect ED Uptake by People With Sickle Cell Disease
May 2025
Although prescription drug monitoring programs (PDMPs) may help prescribers identify patients at risk of opioid misuse, they may also have unintended negative effects, such as increased illicit drug use. They can also negatively affect those with sickle cell disease (SCD) who often seek treatment in the emergency department (ED) for vaso-occlusive crises.
Daratumumab-Containing Quadruplet Effective as First-Line in Transplant-Ineligible NDMM, Randomized Trial Finds
May 2025
A quadruplet regimen comprising an anti-CD38 monoclonal antibody daratumumab plus bortezomib, lenalidomide, and dexamethasone as first-line treatment resulted in dramatically improved rates of measurable residual disease negativity than the same regimen without daratumumab in patients with newly diagnosed multiple myeloma (NDMM) who were ineligible or deemed to be unfit for a hematopoietic cell transplant.
