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Clotting Disorders

December 20, 2021

A collection of features and news articles published in ASH Clinical News related to clotting disorders.

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Relapse-Free Survival Progressively Shortens in Black Patients With Rituximab-Treated iTTP

In patients with relapsing immune thrombotic thrombocytopenic purpura (iTTP), successive rituximab treatment shortens relapse-free survival (RFS), a finding most pronounced ...

CRP Levels May Help Stratify VTE Risk in Patients With Cancer on ICIs

C-reactive protein (CRP) levels may help identify patients on immune checkpoint inhibitors (ICIs) who are at increased risk of venous thromboembolism (VTE) ...

Reduced Dose of DOACs May Reduce Bleeding, Health Care Usage in VTE Management

During the 66th American Society of Hematology Annual Meeting and Exposition, Jordan K. Schaefer, MD, MSc, of the University of Michigan in Ann Arbor ...

Bispecific Antibody Elicits High Responses Among Patients With Heavily Pretreated CLL

Patients with heavily pretreated, relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) treated with epcoritamab, a bispecific antibody, had a high overall response rate ...

MRD-Guided Therapy Improves Quality of Life for Patients With CLL

Time-limited treatment with ibrutinib plus venetoclax in patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) guided by measurable residual disease ...

CAR-T Produces Good Long-Term Outcomes in R/R CLL, Analysis Finds

Patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) treated with anti-CD19 chimeric antigen receptor (CAR) T-cell therapy who achieved a complete response ...

AI Algorithm Using ECG, D-Dimer Provides Impressive Accuracy for PE Diagnosis

Artificial intelligence (AI) applications in hematology offer the possibility of radical innovations in disease diagnostics. At a session of the 66th American Society ...

Eliminating Modifiable Risk Factors Lowers Bleeding Risk in Patients With Cancer, VTE, Study Finds

Anemia and hypertension were the two modifiable risk factors most closely related to anticoagulant-associated bleeding risk in patients with cancer ...

Researchers Identify Risk Factors for Venous Thromboembolism in Women with Obesity Who Undergo Cesarean Delivery

Obstetricians recognize that the prevalence and morbidity of venous thromboembolism (VTE) in the peripartum period contributes significantly to maternal death. New research indicates ...

Caplacizumab Improves ADAMTS13 Recovery in Patients with iTTP

Caplacizumab, a humanized nanobody, blocks the interaction between von Willebrand factor and platelets. While early administration of caplacizumab in patients with the rare disease immune ...

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