Researchers Identify Risk Factors for Venous Thromboembolism in Women with Obesity Who Undergo Cesarean Delivery
Obstetricians recognize that the prevalence and morbidity of venous thromboembolism (VTE) in the peripartum period contributes significantly to maternal death. New research indicates ...
Caplacizumab Improves ADAMTS13 Recovery in Patients with iTTP
Caplacizumab, a humanized nanobody, blocks the interaction between von Willebrand factor and platelets. While early administration of caplacizumab in patients with the rare disease immune ...
Apixaban Produces More Favorable Results Than Rivaroxaban, Warfarin in AF, VTE
In patients on direct oral anticoagulants (DOACs) for atrial fibrillation (AF) and venous thromboembolism (VTE), treatment with apixaban resulted in less bleeding and was associated with ...
No Change in Platelet Count Threshold of Patients With ITP Treated With Aspirin
Patients with immune thrombocytopenia (ITP) and a platelet count of less than 20 × 109/L who were treated with aspirin experienced bleeding at similar rates as patients with ITP who were ...
Study Suggests Iron Homeostasis Is Key in Pregnancy Outcomes in Thalassemic Mice
Adverse pregnancy outcomes in thalassemic (Th3/+) mice, such as placenta enlargement and growth restriction, could be related to iron overload in a way not previously appreciated ...
Site of Cancer Could Predict VTE Recurrence After Anticoagulation Cessation
Despite having active cancer, patients who have surgery-associated venous thromboembolism (VTE) may only require time-limited anticoagulation ...
Recombinant ADAMTS13 Yielded Higher ADAMTS13 Exposure Compared With Plasma Exchange for iTTP
Recombinant ADAMTS13 (rADAMTS13) plus plasma exchange increased ADAMTS13 exposure in patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP) compared with placebo plus plasma exchange ...
Efgartigimod Shows Long-Term Safety, Efficacy in Long-Standing Primary ITP
An interim analysis of the open-label extension ADVANCE+ study suggests that long-term efgartigimod has an acceptable side effect profile and is not associated with increased exposure-adjusted risk ...
Silent Cerebral Infarction During iTTP Can Affect Cognition
Silent cerebral infarction (SCI) refers to the often-incidental finding of brain infarction in the absence of overt neurologic deficits. Magnetic resonance imaging (MRI) evidence suggests that ...
COVID-19 Bivalent Boosters Associated With Few Definitive Hematologic AEs
A cross-sectional study of U.S. safety data found few hematologic adverse events (AEs) after administration of the authorized COVID-19 bivalent booster vaccines from Pfizer-BioNTech and Moderna ...
