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You Make the Call

Each month we’ll pick a challenging clinical question submitted through the Consult-a-Colleague program and post the expert’s response.
You Make the Call: How would you diagnose and treat a patient presenting with profound thrombocytopenia and signs of an MPN? Free
May 28, 2025
You Make the Call: Would you rule out porphyria in this patient? Free
May 1, 2025
You Make the Call: How would you treat an older patient presenting with cardiomyopathy, refractory AF, and findings suggestive of cardiac amyloidosis? Free
April 2, 2025
You Make the Call: How would you manage a patient with a history of beta thalassemia major and pancytopenia who requires frequent blood transfusions? Free
February 26, 2025
You Make the Call: Would you treat this patient for myelodysplastic syndromes or paroxysmal nocturnal hemoglobinuria? Free
January 30, 2025
You Make the Call: Would you recommend a phlebotomy for a patient with a high ferritin level and H63D gene mutation? Free
January 15, 2025
You Make the Call: How would you treat a young patient with minimally symptomatic CLL? Free
November 26, 2024
You Make the Call: How would you treat progressive classical Hodgkin lymphoma after multiple lines of therapy? Free
November 21, 2024
You Make the Call: How would you treat a patient with a history of bilateral PE and subsequent DVT? Free
November 1, 2024
You Make the Call: How would you treat a patient with erythroderma and progressive eosinophilia? Free
September 27, 2024
You Make the Call: How would you treat venous sinus thrombosis in a patient with heterozygous prothrombin mutation and on testosterone replacement? Free
August 29, 2024
You Make the Call: How would you treat a patient with AML and persistent MRD post-HCT? Free
July 31, 2024
You Make the Call: How would you treat a patient with a family history of methemoglobinemia and Hb M-Iwate mutation? Free
June 26, 2024
You Make the Call: What treatment would you recommend for a patient with Philadelphia chromosome-positive B-ALL? Free
May 30, 2024
You Make the Call: Would you treat borderline anemic pregnant patients with oral or intravenous iron? Free
April 30, 2024
You Make the Call: How would you treat a patient with acute promyelocytic leukemia and CNS disease? Free
March 26, 2024
You Make the Call: What prophylactic treatment would you recommend for a basketball player who has had multiple episodes of hematoma? Free
February 23, 2024
You Make the Call: Would you proceed with a 7/8 matched unrelated donor alloHCT in a patient with severe acquired aplastic anemia? Free
February 1, 2024
You Make the Call: What second-line therapies would you recommend for Rosai-Dorfman disease following a modest partial response to prednisone? Free
January 9, 2024
You Make the Call: Would you start a patient who presented with a left cerebrovascular accident likely due to oral contraceptive use on warfarin? Free
November 30, 2023

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June 2025

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