Telemedicine Approach Helps Improve IC-Based SCD Pain Management
An approach that uses telemedicine for triage has helped patients with sickle cell disease (SCD) get infusion center (IC)-based treatment without having to go through the emergency department ...
Study Confirms Safety, Efficacy of Mitapivat to Improve Anemia, Decrease Pain Crises in Sickle Cell Disease
Sickle cell disease (SCD) affects millions of people worldwide and causes reduced quality of life (QoL), negative clinical outcomes, unpredictable pain, anemia, and shortened lifespan ...
Danicopan Plus Ravulizumab, Eculizumab Shows Long-Term Efficacy in PNH With Clinically Significant EVH
In patients with paroxysmal nocturnal hemoglobinuria (PNH) and clinically significant extravascular hemolysis (cs-EVH), treatment with the oral factor D inhibitor danicopan plus C5 inhibitors (C5i) ravulizumab and ...
Patient Motivators Key for Participation in SCD Clinical Trials
During a poster session at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition, Biree Andemariam, MD, a hematologist and founding director of the New England Sickle Cell Institute ...
Considerable Morbidity, Mortality Seen in AIHA, Making Case for Early Testing, Long-Term Study Finds
In a look at long-term observational data on the clinical features and course of disease for children with autoimmune hemolytic anemia (AIHA), patients were frequently found to have an underlying immune disorder ...
Study Validates SCD Biomarker for Targeted P-Selectin Therapy Response
In patients with sickle cell disease (SCD), assessing adhesion phenotypes using the flow adhesion of whole blood to p-selectin (FA-WB-PSel) biomarker enabled clinicians to identify biologic responders versus ...
Creatinine May Outperform Cystatin C in eGFR Calculations in SCD
Data presented at a poster session of the 66th American Society of Hematology Annual Meeting and Exposition suggest that creatinine-based equations to estimate glomerular filtration rate ...
New Therapy May Be Effective for Patients With Cold Agglutinin Disease, Warm Antibody Autoimmune Hemolytic Anemia
Pegcetacoplan increased hemoglobin (Hb) levels, reduced hemolysis, and increased FACIT-fatigue scale scores in the first weeks of treatment in patients with cold agglutinin disease (CAD) and those with warm ...
Lactated Ringer Preferred Over Normal Saline in SCD Vaso-Occlusive Episodes
Findings from a retrospective target-trial emulation study published in JAMA Internal Medicine demonstrate that balanced fluids such as lactated Ringer (LR) solution may promote better ...
CDC Guideline Results in Drop in Opioid Prescriptions for Patients with SCD
In 2016, the U.S. Centers for Disease Control and Prevention (CDC) released the Guideline for Prescribing Opioids for Chronic Pain to provide recommendations to primary care clinicians who prescribe ...
