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Bleeding Disorders

December 20, 2021

A collection of features and news articles published in ASH Clinical News related to bleeding disorders.

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AI-Assisted POCUS Could Help Identify Joint Bleeds in Hemophilia

Technology combining artificial intelligence (AI) and point-of-care ultrasonography (POCUS) could assist clinicians with early detection and management of hemarthrosis in patients ...

High Incidence of Postpartum Hemorrhage Seen in Hemophilia Carriers

To help prevent postpartum hemorrhage (PPH), international guidelines recommend that certain hemophilia carriers (HC) receive supplemental clotting factor at the time of childbirth ...

Pomalidomide Found Safe, Highly Effective for Epistaxis in HHT

An observational study that was presented in an oral abstract session at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition suggested the utility of ...

Large Study Compares Serum Thrombopoietin Levels in Pediatric Patients With Acquired Aplastic Anemia, Immune Thrombocytopenia

A large, single-center analysis of pediatric patients with either acquired aplastic anemia (aAA) or immune thrombocytopenia (ITP) has compared the serum thrombopoietin (TPO) levels in these ...

Etranacogene Dezaparvovec Bests Extended Half-Life Factor IX Products in Hemophilia B Prophylaxis

For patients with severe or moderately severe hemophilia B, a single dose of etranacogene dezaparvovec gene therapy reduced bleeding rates and eliminated routine infusions associated with ...

Emicizumab Effective as a Hemophilia A Prophylaxis in Infants

The bispecific monoclonal antibody emicizumab was an effective prophylactic treatment for infants with severe hemophilia A without factor VIII (FVIII) inhibitors, according to data from ...

Age Linked to Desmopressin Response in von Willebrand Disease

Response to desmopressin in patients with von Willebrand disease (VWD) and low von Willebrand factor (VWF) level improves as they get older, according to findings presented at ...

Health Disparities Persist in Hemophilia Life Expectancy

Between 1999 and 2020, recorded hemophilia death (rHD) rates in the U.S. improved in males across all racial and ethnic groups ...

Ultrasound May Be Useful to Assess Subclinical Synovial Inflammation in Hemophilia

A study published in Haemophilia highlights the potential utility of ultrasound screenings to assess preclinical joint damage in ...

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