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Journal Articles

In Vivo Crispr Screening Identifies Novel Vulnerabilities in ETO2/GLIS2- rearranged Leukemia

Mark Wunderlich, Jason Clark, Jing Chen, Lynn Lee
Journal: Blood
Blood (2022) 140 (Supplement 1): 3431–3432.
https://doi.org/10.1182/blood-2022-169837
Published: 2022
Journal Articles

High-Risk Langerhans Cell Histiocytosis in Infants Exhibits Malignant Features in a Xenograft Model but Responds Durably to Targeted Therapy

Lynn Lee, MD, Mary Christa Krupski, DO, MPH, Jason Clark, MS, Robert B. Lorsbach, MD PhD, Michael Grimley, MD, Matthew Burwinkel, Adam S. Nelson, MBBS, Ashish R Kumar, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4323.
https://doi.org/10.1182/blood-2018-99-119383
Published: 2018
Journal Articles

MLL-Fusion Leukemia Dependence on MBNL1 Is Associated with Alternative Splicing of Oncogenic Proteins

Arun Gurunathan, MD, Lana S Itskovich, PhD, Jason Clark, MS, Matthew Burwinkel, Nathan Salomonis, PhD, Meenakshi Venkatasubramanian, BS, Kashish Chetal, MS, Lynn Lee, MD, Ashish R Kumar, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3883.
https://doi.org/10.1182/blood-2018-99-112349
Published: 2018
Journal Articles

The Role of LAMP5 in Innate Immune Signaling Is Critical for the Survival of MLL Leukemias

Gabriel Gracia-Maldonado, BS, Jason Clark, MS, Philippe Pierre, PhD, James C. Mulloy, PhD, Ashish R Kumar, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3900.
https://doi.org/10.1182/blood-2018-99-120190
Published: 2018
Journal Articles

Real-Time Genomic Profiling Identifies Novel Mutations and Improved Therapy for Histiocytoses

Lynn Lee, MD, Anjelika Gasilina, Jayeeta Roychoudhury, PhD, Jason Clark, Francis X McCormack, MD, Joseph Gerald Pressey, MD, Robert B. Lorsbach, MD PhD, Siraj M Ali, MD PhD, Mark Bailey, MSc, Philip Stevens, PhD, Jeffrey S Ross, MD, Vincent A. Miller, MD, Nicolas Nassar, PhD, Ashish R Kumar, MBBS, PhD
Journal: Blood
Blood (2016) 128 (22): 2723.
https://doi.org/10.1182/blood.V128.22.2723.2723
Published: 2016
Journal Articles

LAMP5 - a Novel Target of MLL-Fusion Proteins Is Required for the Propagation of Leukemia

Gabriel Gracia-Maldonado, Jason Clark, James C. Mulloy, PhD, Ashish R Kumar, MBBS, PhD
Journal: Blood
Blood (2016) 128 (22): 1512.
https://doi.org/10.1182/blood.V128.22.1512.1512
Published: 2016
Journal Articles

Susceptibility of AML to Chloroquine Therapy Is Independent of Autophagy

Xiaoyi Chen, PhDcandidate, Jason Clark, Jun-lin Guan, PhD, Ashish R Kumar, MBBS, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2015) 126 (23): 1262.
https://doi.org/10.1182/blood.V126.23.1262.1262
Published: 2015
Journal Articles

MBNL1 As a New Therapeutic Target in MLL-Fusion Gene Leukemia

Svetlana S Itskovich, PhD, Jason Clark, James C. Mulloy, PhD, Matthew D Disney, Ashish R Kumar, MBBS, PhD
Journal: Blood
Blood (2015) 126 (23): 462.
https://doi.org/10.1182/blood.V126.23.462.462
Published: 2015
Journal Articles

Primary Analysis Results from an Open-Label Phase II Study of INCB039110, a Selective JAK1 Inhibitor, in Patients with Myelofibrosis

John O Mascarenhas, MD MS, Moshe Talpaz, Vikas Gupta, MD FRCP, FRCPath, Lynda M Foltz, MD FRCP, Michael R Savona, MD, Ron Paquette, MD, Robert Turner, MD, Paul Coughlin, PhD MBBS, Elliott Winton, MD, Deborah Hunter, PhD, Albert Assad, MD, Jason Clark, PhD, Peter O'Neill, MBA, CCRP, Ronald Hoffman, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2014) 124 (21): 714.
https://doi.org/10.1182/blood.V124.21.714.714
Published: 2014
Journal Articles

An Open-Label, Phase II Study Of The JAK1 Inhibitor INCB039110 In Patients With Myelofibrosis

John Mascarenhas, MD, Moshe Talpaz, MD, Vikas Gupta, MD, FRCP, FRCPath, Michael Savona, MD, FACP, Paul Coughlin, FRACP, PhD, Elliott Winton, MD, Deborah Hunter, PhD, Bijoyesh Mookerjee, MD, FACP, Lance Leopold, MD, Jason Clark, PhD, Peter O'Neill, MBA, CCRP, Ronald Hoffman, MD, Srdan Verstovsek, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 663.
https://doi.org/10.1182/blood.V122.21.663.663
Published: 2013