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Research Article February 3 2023
The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53
Maria-Riera Piqué-Borràs,Zivojin Jevtic,Frederik Otzen Bagger,Jonathan Seguin,Rathick Sivalingam,Matheus Filgueira Bezerra,Amber Louwaige,Sabine Juge,Ioannis Nellas,Robert Ivanek,Alexandar Tzankov,Ute Moll,Oriano Valerio Cantillo,Ramona Schultz-Heddergott,Alexandre Fagnan,Thomas Mercher,Juerg Schwaller
Research Article February 3 2023
Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A
Pedro Gonzalez-Menendez,Ira Phadke,Meagan E Olive,Axel Joly,Julien Papoin,Hongxia Yan,Jérémy Galtier,Jessica Platon,Sun Woo Sophie Kang,Kathy L. McGraw,Marie Daumur,Marie Pouzolles,Taisuke Kondo,Stéphanie Boireau,Franciane Paul,David J Young,Sylvain Lamure,Raghavendra G Mirmira,Anu Narla,Guillaume Cartron,Cynthia E. Dunbar,Myriam Boyer-Clavel,Natalie Porat-Shliom,Valerie Dardalhon,Valerie S Zimmermann,Marc Sitbon,Thomas Dever,Narla Mohandas,Lydie M Da Costa,Namrata D. Udeshi,Lionel Blanc,Sandrina Kinet,Naomi Taylor
Research Article February 3 2023
Recombinant Factor VIII Fc Fusion Protein for First-time Immune Tolerance Induction: Final Results of the verITI-8 Study
Review Article February 3 2023
Resolving the hematopoietic stem cell state by linking functional and molecular assays
Research Article February 3 2023
Targeting the immune microenvironment in Waldenström Macroglobulinemia via halting the CD40/CD40-ligand axis
Antonio Sacco,Vanessa Desantis,Jon Celay,Viviana Giustini,Fabio Rigali,Francesco D Savino,Michele Cea, Prof,Debora Soncini,Antonia Cagnetta,Antonio Giovanni Solimando,Deborah D'Aliberti,Silvia Spinelli,Daniele Ramazzotti,Camillo Almici,Katia Todoerti,Antonino Neri, Dr,Antonella Anastasia,Alessandra Tucci,Marina Motta, MD,Marco Chiarini,Yawara Kawano,Jose-Al Martinez-Climent,Rocco Piazza,Aldo M Roccaro
Letter February 3 2023
Predictive value of staging PET/CT to detect bone marrow involvement and early outcomes in marginal zone lymphoma
Review Article February 1 2023
Consensus proposal for revised International Working Group response criteria for higher risk myelodysplastic syndromes
Amer M. Zeidan,Uwe Platzbecker,Jan Philipp Bewersdorf,Maximilian Stahl,Lionel Adès,Uma Borate,David T Bowen,Rena J. Buckstein,Andrew M. Brunner,Hetty E Carraway,Naval G. Daver,Maria Díez-Campelo,Theo M de Witte,Amy E. DeZern,Fabio Efficace,Guillermo Garcia-Manero,Jacqueline S. Garcia,Ulrich Germing,Aristoteles Giagounidis,Elizabeth A Griffiths,Robert P Hasserjian,Eva Hellström-Lindberg,Marcelo C Iastrebner,Rami S. Komrokji,Austin G Kulasekararaj,Luca Malcovati,Yasushi Miyazaki,Olatoyosi Odenike,Valeria Santini,Guillermo F. Sanz,Phillip Scheinberg,Reinhard Stauder,Arjan A Van de Loosdrecht,Andrew H Wei,Mikkael A. Sekeres,Pierre Fenaux
Research Article February 1 2023
The influence of microbial dysbiosis on immunochemotherapy-related efficacy and safety in diffuse large B-cell lymphoma
Research Article January 30 2023
Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia
Stephen K. Tahir,Emiliano Calvo,Benedito A. Carnero,Junichiro Yuda,Aditya Shreenivas,Mojca Jongen-Lavrencic,Eelke Gort,Kenichi Ishizawa,Daniel Morillo,Carla Biesdorf,Morey Smith,Dong Cheng,Monica Motwani,David Sharon,Tamar Uziel,Dimple A. Modi,Fritz G. Buchanan,Susan Morgan-Lappe,Bruno C. Medeiros,Darren C. Phillips
Research Article January 27 2023
Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease
Erica M Sparkenbaugh,Michael W. Henderson,Megan D Miller-Awe,Christina Abrams,Anton Ilich,Fatima Trebak,Nirupama Ramadas,Shantel A Vital,Dillon Bohinc,Kara Bane,Chunsheng Chen,Margi Patel,Michael Wallisch,Thomas Renné,Andras Gruber,Brian Cooley,David Gailani,Malgorzata Kasztan,Gregory M Vercellotti,John D Belcher,Felicity N. E. Gavins,Evi X. Stavrou,Nigel S Key,Rafal Pawlinski
Research Article January 27 2023
Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease
Livius Penter,Yang Liu,Jacquelyn O Wolff,Lin Yang,Len Taing,Aashna Jhaveri,Jackson Southard,Manishkumar Patel,Nicole Cullen,Kathleen Lindahl Pfaff,Nicoletta Cieri,Giacomo Oliveira,Seunghee Kim-Schulze,Srinika Ranasinghe,Rebecca Leonard,Taylor Robertson,Elizabeth A. Morgan,Helen Chen,Minkyung H Song,Magdalena Thurin,Shuqiang Li,Scott J Rodig,Carrie Cibulskis,Stacey Gabriel,Pavan Bachireddy,Jerome Ritz,Howard Streicher,Donna Neuberg,F Stephen Hodi,Sacha Gnjatic,Matthew S. Davids,Kenneth J Livak,Jennifer Altreuter,Franziska Michor,Robert J. Soiffer,Jacqueline S. Garcia,Catherine J. Wu
Brief Report January 27 2023
AUTOIMMUNE HEMOLYTIC ANEMIA DURING PREGNANCY AND PUERPERIUM: AN INTERNATIONAL MULTI-CENTER EXPERIENCE
Bruno Fattizzo,Marta Bortolotti,Norma Nadia Fantini,Andreas Glenthøj,Marc Michel,Mariasanta Napolitano,Simona Raso,Frederick Chen,Vickie McDonald,Irina Murakhovskaya,Josephine M.I. Vos,Andrea Patriarca,Maria Eva Mingot-Castellano,Giulio Giordano,Margherita Scarrone,Tomas Jose Gonzalez-Lopez,Laura Trespidi,Daniele Prati,Wilma Barcellini
Research Article January 26 2023
C1 inhibitor deficiency enhances contact pathway mediated activation of coagulation and venous thrombosis
Research Article January 25 2023
Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms
Amelie Jaeger,Sudheer Madan Mohan Gambheer,Xiaoyang Sun,Dmitry Chernyakov,Oleksandra Skorobohatko,Thomas M. Mack,Sandra Kissel,Dietmar Pfeifer,Robert Zeiser,Paul Fisch,Geoffroy Andrieux,Daniela Bräuer-Hartmann,Marcus Bauer,Susann Schulze,Marie Follo,Melanie Boerries,Nikolas von Bubnoff,Cornelius Miething,Jose Villacorta Hidalgo,Claudius Klein,Thomas Weber,Claudia Wickenhauser,Mascha Binder,Christine Dierks
Research Article January 25 2023
Potentiating antibody-dependent killing of cancers with CAR T cells secreting CD47-SIRPα checkpoint blocker
Research Article January 24 2023
How I Treat Multiple myeloma in the geriatric patient
Review Article January 20 2023
Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT)
Research Article January 18 2023
Approach to Bleeding in the Hospitalized Patient
Research Article January 18 2023
A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic datasets
Caitlyn Vlasschaert,Taralynn Mack,Jonathan Brett Heimlich,Abhishek Niroula,Md Mesbah Uddin,Joshua S Weinstock,Brian Sharber,Alexander J. Silver,Yaomin Xu,Michael R. Savona,Christopher J. Gibson,Matthew B. Lanktree,Michael J Rauh,Benjamin L. Ebert,Pradeep Natarajan,Siddhartha Jaiswal,Alexander G. Bick
Research Article January 13 2023
Prior Immunization to an Intracellular Antigen Enhances Subsequent Red Blood Cell Alloimmunization in Mice
Research Article January 13 2023
Fecal microbiota transplantation from young mice rejuvenates aged hematopoietic stem cells by suppressing inflammation
Research Article January 13 2023
Patients with Asian-type DEL can safely be transfused using RhD-positive blood
Yanli Ji,Yalin Luo,Jizhi Wen,Yuanfan Sun,Shuangshuang Jia,Chunquan Ou,Wenbing Yang,Jingwang Chen,Hanshen Ye,Xiangfu Liu,Yongneng Liang,Zhigang Lu,Ying Feng,Xinzhong Wu,Muzhou Xiao,Jiankun Mo,Zhenhai Zhou,Zhen Wang,Zhijian Liao,Junhu Chen,Ling Wei,Guangping Luo,Sentot Santoso,Yann Fichou,Willy A Flegel,Chaopeng Shao,Chengyao Li,Rui Zhang,Yongshui Fu
Research Article January 12 2023
Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity
Research Article January 11 2023
Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma
Research Article January 11 2023
SBNO2 is a critical mediator of STAT3-driven hematological malignancies
Brief Report January 10 2023
Rare Germline Complement Factor H Variants in Patients with Paroxysmal Nocturnal Hemoglobinuria
Research Article January 10 2023
Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures
Benjamin T. Diamond,Bachisio Ziccheddu,Kylee H. Maclachlan,Justin Taylor,Eileen Mary Boyle,Juan Esteban Arango Ossa,Thomas Jacob Jahn,Maurizio Affer,Tulasigeri M. Totiger,David G Coffey,Namrata Chandhok,Justin M Watts,Luisa Cimmino,Sydney X Lu,Niccolo Bolli,Kelly L Bolton,Heather J. Landau,Jae H. Park,Karuna Ganesh,Andrew McPherson,Mikkael A. Sekeres,Alexander M Lesokhin,David J. Chung,Yanming Zhang,Caleb Ho,Mikhail Roshal,Jeffrey W Tyner,Stephen D Nimer,Elli Papaemmanuil,Saad Z. Usmani,Gareth J Morgan,Ola Landgren,Francesco Maura
Research Article January 10 2023
Polatuzumab vedotin in previously untreated DLBCL: an Asia subpopulation analysis from the Phase 3 POLARIX trial
Yuqin Song,Herve Tilly,Shinya Rai,Huilai Zhang,Jie Jin,Hideki Goto,Yasuhito Terui,Ho-Jin Shin,Won Seog S Kim,Junning Cao,Jifeng Feng,Hyeon-Seok Eom,Tae Min Kim,Xavier Cheng-Hong Tsai,Jyh-Pyng Gau,Hideo Koh,Liling Zhang,Yongping Song,Yu Yang,Wei Li,He Huang,Kiyoshi Ando,Jeff P. Sharman,Laurie H Sehn,Lilian Bu,Xin Wang,Yanwen Jiang,Jamie Hirata,Calvin Lee,Jun Zhu,Koji Izutsu
Letter January 10 2023
Monoclonal Gammopathy of Thrombotic/thrombocytopenic Significance
Editorial January 6 2023
INTRODUCTION TO A REVEW SERIES ON BANKED ALLOGENEIC IMMUNE EFFECTOR CELLS
Brief Report January 6 2023
A phase II clinical trial of combined BRAF/MEK inhibition for BRAFV600E-mutated multiple myeloma
Nicola Giesen,Manik Chatterjee,Christof Scheid,Alexandra M Poos,Britta Besemer,Kaya Miah,Axel Benner,Nicole Becker,Thomas Moehler,Ivana Metzler,Cyrus Khandanpour,Andrea Seidel-Glaetzer,Karolin Trautmann-Grill,K. Martin Kortüm,Carsten Müller-Tidow,Gunhild Mechtersheimer,Benjamin Goeppert,Albrecht Stenzinger,Niels Weinhold,Hartmut Goldschmidt,Katja C. Weisel,Marc S. Raab
Research Article January 5 2023
High-Dose Melphalan Treatment Significantly Increases Mutational Burden at Relapse in Multiple Myeloma
Mehmet K. Samur,Marco Roncador,Anil Aktas Samur,Mariateresa Fulciniti,Abdul-Hamid Bazarbachi,Raphael E. Szalat,Masood A Shammas,Adam S. Sperling,Paul G. Richardson,Florence Magrangeas,Stephane Minvielle,Aurore Perrot,Jill Corre,Philippe Moreau,Anjan Thakurta,Giovanni Parmigiani,Kenneth C. Anderson,Hervé Avet-Loiseau,Nikhil C. Munshi
Research Article January 5 2023
Central Nervous System Status is Prognostic in T-Cell Acute Lymphoblastic Leukemia: A Children's Oncology Group Report
Nathan Gossai,Meenakshi Devidas,Zhiguo Chen,Brent L. Wood,Patrick A Zweidler-McKay,Karen R. Rabin,Mignon L. Loh,Elizabeth A. Raetz,Naomi J Winick,Michael J Burke,Andrew J. Carroll,Natia Esiashvili,Nyla A. Heerema,William L Carroll,Stephen P. Hunger,Kimberly P. Dunsmore,Stuart Sheldon Winter,David T. Teachey
Research Article January 4 2023
INPP5K controls the dynamic structure and signaling of wild type and mutated, leukemia-associated IL7 receptors
Letter January 4 2023
Prognostic value and oncogenic landscape of TP53 alterations in adult and pediatric T-ALL
Mathieu Simonin,Guillaume P Andrieu,Rudy Birsen,Marie Balsat,Guillaume Hypolite,Lucien Courtois,Carlos Graux,Nathalie Grardel,Jean-Michel Cayuela,Françoise Huguet,Yves Chalandon,Yannick Le Bris,Elizabeth A. Macintyre,Virginie Gandemer,Arnaud Petit,Philippe Rousselot,André Baruchel,Didier Bouscary,Olivier Hermine,Nicolas Boissel,Vahid Asnafi
Research Article December 29 2022
DNA polymerase theta protects leukemia cells from metabolic-induced DNA damage
Umeshkumar Vekariya,Monika Maria Toma,Margaret Nieborowska-Skorska,Bac Viet Le,Marie-Christine Caron,Anna-Mariya Kukuyan,Katherine Sullivan-Reed,Paulina Podszywalow-Bartnicka,Kumaraswamy Naidu Chitrala,Jessica Atkins,Malgorzata Drzewiecka,Wanjuan Feng,Joe Chan,Srinivas Chatla,Konstantin Golovine,Jaroslav Jelinek,Tomasz Sliwinski,Jayashri Ghosh,Ksenia Matlawska-Wasowska,Gurushankar Chandramouly,Reza Nejati,Mariusz A Wasik,Stephen Sykes,Katarzyna Piwocka,Emir Hadzijusufovic,Peter Valent,Richard T Pomerantz,George Morton,Wayne Childers,Huaqing Zhao,Elisabeth Paietta,Ross L. Levine,Martin S. Tallman,Hugo Fernandez,Mark R Litzow,Gaorav Gupta,Jean-Yves Masson,Tomasz Skorski
Research Article December 28 2022
HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia
Brief Report December 27 2022
Non-steroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal Hematodiaphyseal Dysplasia
Research Article December 27 2022
Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of GvHD
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