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Research Article December 19 2024
Long-Term Efficacy and Safety of Danicopan as Add-On Therapy to Ravulizumab or Eculizumab in PNH With Significant EVH
Brief Report December 19 2024
Approaching Hypercalcemia in Monoclonal Gammopathy of Undetermined Significance: Insights from the iStopMM study
Ástrún Helga Jónsdóttir,Helga Ágústa Sigurjónsdóttir, Prof.,Sigrun Thorsteinsdottir,Thorir Einarsson Long,Ingigerður Sólveig Sverrisdóttir,Elias Eythorsson,Jon Thorir Oskarsson,Runólfur Pálsson,Olafur Skuli Indridason,Bryjnar Vidarsson,Pall T Onundarson,Isleifur Olafsson,Ingunn Þorsteinsdóttir,Bjarni A Agnarsson,Margret Sigurdardottir,Asbjorn Jonsson,Malin L. Hultcrantz,Brian G.M. Durie,Stephen Harding,Carl Ola Landgren,Thorvardur Jon Love,Sigurdur Yngvi Kristinsson,Sæmundur Rögnvaldsson
Review Article December 19 2024
How I treat quantitative fibrinogen disorders
Research Article December 18 2024
Deficiency of neutrophil gelatinase-associated lipocalin elicits Hemophilia-like bleeding and clotting disorder
Research Article December 18 2024
Mutations in AMBRA1 aggravate β-thalassemia by impairing autophagy-mediated clearance of free α-globin
Research Article December 18 2024
Oral Inflammation and Microbiome Dysbiosis Exacerbate Chronic Graft-versus-host Disease
Yui Kambara,Hideaki Fujiwara,Akira Yamamoto,Kazuyoshi Gotoh,Shuma Tsuji,Mari Kunihiro,Tadashi Oyama,Toshiki Terao,Ayame Sato,Takehiro Tanaka,Daniel Peltier,Keisuke Seike,Hisakazu Nishimori,Noboru Asada,Daisuke Ennishi,Keiko Fujii,Nobuharu Fujii,Ken-ichi Matsuoka,Yoshihiko Soga,Pavan Reddy,Yoshinobu Maeda
Research Article December 18 2024
Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis
Research Article December 16 2024
DLBclass: A Probabilistic Molecular Classifier to Guide Clinical Investigation and Practice in DLBCL
Research Article December 11 2024
Single-cell epigenetic and clonal analysis decodes disease progression in pediatric acute myeloid leukemia
Research Article December 10 2024
Inflammation-driven NFκB signaling represses Ferroportin transcription in macrophages via HDAC 1 and 3
Research Article December 10 2024
IFN-I promotes T cell-independent immunity and RBC autoantibodies via modulation of B-1 cell subsets in murine SCD
Research Article December 10 2024
An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.
Research Article December 10 2024
Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation
Fabien Boudia,Marie Baille,Loelia Babin,Zakia Aid,Elie Robert,Julie Riviere,Klaudia Galant,Verónica Alonso-Pérez,Laura Anselmi,Brahim Arkoun,Nassera Abermil,Christophe Marzac,Salvatore Nicola Bertuccio,Alexia Regnault de Premesnil,Cecile K. Lopez,Alexandre Eeckhoutte,Audrey Naimo,Betty Leite,Cyril Catelain,Christophe Metereau,Patrick Gonin,Nathalie Gaspar,Juerg Schwaller,Olivier A Bernard,Hana Raslova,Murielle Gaudry,Antonin Marchais,Hélène Lapillonne,Arnaud Petit,Francoise Pflumio,Marie-Laure Arcangeli,Erika Brunet,Thomas Mercher
Research Article December 9 2024
Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation
Viral Shah,George Giotopoulos,Hikari Osaki,Markus Meyerhöfer,Eshwar Meduri,Aaron Gallego-Crespo,Malte Andreas Behrendt,Maria Saura-Pañella,Aarti Tarkar,Benedict Schubert,Haiyang Yun,Sarah J. Horton,Shuchi Agrawal-Singh, Dr,Patricia S Hähnel,Faisal Basheer,Dave Lugo,Ioanna Eleftheriadou,Olena Barbash,Arindam Dhar,Michael Kühn,Borhane Guezguez,Matthias Theobald,Thomas Kindler,Paolo Gallipoli,Paul Sung-Hao Yeh,Mark A. Dawson,Rab K Prinjha,Brian JP Huntly,Daniel Sasca
Research Article December 9 2024
Tumor burden quantified by Soluble B-Cell Maturation Antigen and Metabolic Tumor Volume determine myeloma CAR-T outcomes
Ciara L Freeman,Jerald Noble,Meghan Menges,Ricardo Villanueva,Justyn Y Nakashima,Nicholas B Figura,R. Petter Tonseth,Dietrich Werner Idiaquez,Lawrence Skelson,Eric C Smith,Julieta Abraham-Miranda,Salvatore Corallo,Gabriel De Avila,Omar Castaneda Puglianini,Hien D Liu,Melissa Alsina,Taiga Nishihori,Kenneth H Shain,Rachid C Baz,Brandon J Blue,Ariel Grajales-Cruz,John M. Koomen,Reginald M Atkins,Doris K Hansen,Ariosto Siqueira Silva,Jongphil Kim,Yoganand Balagurunathan,Frederick L Locke
Research Article December 9 2024
Anti-CD19 antibody cotreatment enhances serial killing activity of anti-CD19 CAR-T/-NK cells and reduces trogocytosis
Research Article December 9 2024
The GATA-3-dependent transcriptome and tumor microenvironment are regulated by eIF4E and XPO1 in T-cell lymphomas
Nermin Kady,Suhaib Abdelrahman,Ahmar Rauf,Alyssa Burgess,Jonathan Weiss,Hirushi Gunasekara,Neal Thomas Ramseier,Ira P Maine,Alejandro Zevallos-Morales,Vanessa Perez-Silos,Ashley Wolfe,Alexandra Hristov,Noah A Brown,Kedar V Inamdar,Maria Sverdlov,Ying Samuel Hu,Carlos Murga-Zamalloa,Chenguang Wang,Ryan A Wilcox
Research Article December 9 2024
Efficacy and Safety of Venetoclax Plus Azacitidine for Patients With Treatment-Naive High-Risk Myelodysplastic Syndromes
Research Article December 9 2024
Efficacy and Safety of Daratumumab in Intermediate/High-risk Smoldering Multiple Myeloma: Final Analysis of CENTAURUS
Carl Ola Landgren,Ajai Chari,Yael C. Cohen,Andrew Spencer,Peter M Voorhees,Irwindeep Sandhu,Matthew W Jenner,Dean Smith,Michele Cavo,Niels W.C.J. van de Donk,Meral Beksac,Phillippe Moreau,Hartmut Goldschmidt,Diego Vieyra,Linlin Sha,Liang Li,Els Rousseau,Robyn M. Dennis,Robin Carson,Craig C. Hofmeister
Research Article December 6 2024
A New Severe Congenital Neutropenia Syndrome Associated with Autosomal Recessive COPZ1 Mutations
Natalia Borbaran Bravo,Ekaterina Deordieva,Larissa Doll,Mohammad ElGamacy,Benjamin Dannenmann,Joana Azevedo,Alberto Iannuzzo,Selket Delafontaine,Moritz Lehners,Marius Sebastian Theo Kolodziej,Birte Hernandez Alvarez,Anna-Sophia Hellmuth,Malte Ritter,Betül Findik,Viktoria Zakharova,Sandro Bräuning,Sergey Kandabarau,Claudia Lengerke,Robert Feil,Isabelle Meyts,Jérôme Delon,Markus F. Templin,Marc Sturm,Olaf Rieß,Cornelia Zeidler,Karl Welte,Anna Shcherbina,Maksim Klimiankou,Julia Skokowa
Review Article December 4 2024
Honing CAR T cells to tackle acute myeloid leukemia
Research Article December 4 2024
BRAFV600E induces key features of LCH in iPSCs with cell type-specific phenotypes and drug responses
Research Article December 4 2024
Targeted interferon therapy with modakafusp alfa for relapsed or refractory multiple myeloma
Research Article December 2 2024
Brentuximab Vedotin, Nivolumab, Doxorubicin, and Dacarbazine for Advanced-Stage Classical Hodgkin Lymphoma
Hun Ju Lee,Rod Ramchandren,Judah Friedman,Jason M. Melear,Ian W. Flinn,John M. Burke,Yuliya Linhares,Paul Alan Gonzales,Matthew Peterson,Mihir Raval,Rangaswamy Chintapatla,Tatyana A. Feldman,Habte A. Yimer,Miguel Islas-Ohlmayer,Ameet Patel,Leland Metheny,Asad Dean,Vishal Rana,Mitul D. Gandhi,John S Renshaw,Linda Ho,Michelle A. Fanale,Wenchuan Guo,Christopher A. Yasenchak
Review Article November 22 2024
The Contribution of the Monocyte‐Macrophage Lineage to Immunotherapy Outcomes
Letter November 22 2024
Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma
F. Smits,Kaz Groen,Mark-David Levin,Claudia Stege,Roel J.W. van Kampen,Ellen van der Spek,Yavuz M. Bilgin,Noortje Thielen,Inger S. Nijhof,Inge Ludwig,Esther G.M. de Waal,Yorick Sandberg,Alain Kentos,Gert-Jan Timmers,Josien C. Regelink,Matthijs Westerman,Koen de Heer,Marie-Christiane MB Vekemans,Nazik Durdu-Rayman,Nicole C.H.P. de Graauw,Maarten R. Seefat,Niels W.C.J. van de Donk,Paula F Ypma,Kazem Nasserinejad,Sonja Zweegman
Research Article November 22 2024
Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome in Haploidentical Transplantation
Research Article November 22 2024
Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe COVID-19
Wen Zhu,Yongwei Zheng,Mei Yu,Nathan Witman,Lu Zhou,Jianhui Wei,Yongguang Zhang,Paytsar Topchyan,Christine Nguyen,Rae Janecke,Anand Padmanabhan,Lisa Baumann Kreuziger,Gilbert C White,Parameswaran Hari,Tongjun Gu,Alexander Thompson Fields,Lucy Kornblith,Richard H Aster,Jieqing Zhu,Weiguo Cui,Shawn M Jobe,Mary Beth Graham,Demin Wang,David Wang,Renren Wen
Research Article November 21 2024
CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML
Research Article November 21 2024
Serum free light chains in a racially diverse population including African Americans and populations from South Africa
Luca Bertamini,Jean-Baptiste Alberge,David Jungpa Lee,Habib El-Khoury,Sungjae Kim,Grace Fleming,Ciara Suen Marie Murphy,Julia Colchie,Maya I Davis,Jacqueline Perry,Elizabeth D Lightbody,Sabine Allam,Lindokuhle N Goqwana,Vinitha Philip,Natalie Anne Smyth, NA,Dhananjay Sakrikar,Mark C Perkins,Stephen Harding,Derek Troske,Gad Getz,Elizabeth W Karlson,Nikhil C. Munshi,Kenneth C. Anderson,Lorenzo Trippa,Catherine R Marinac,Wenlong Carl Chen,Maureen Joffe,Irene M Ghobrial
Letter November 21 2024
Inflammatory Waldenström Macroglobulinemia is associated with clonal hematopoiesis: a multicentric cohort
Pierre-Edouard Debureaux,Stéphanie Poulain,Stephanie Harel,Marie Passet,Marie Templé,Chloe Friedrich,Nathalie Forgeard,Dikelele Elessa,William Plas,Laureen Chat,Gregory Lazarian,Lise Willems,Bruno Royer,Alexis Talbot,Tristan Vaugeois, Dr.,Floriane Theves,Alexandre Terré,Anne C. Brignier,Marion Malphettes,Daphné Krzisch,Laurent Frenzel,Frédéric Davi,Clotilde Bravetti,Florence Nguyen-Khac,Jehan Dupuis,Wendy Cuccuini,Didier Bouscary,Olivier Hermine,Damien Roos-Weil,Olivier Kosmider,Emmanuelle Clappier,Marion Espéli,Karl Balabanian,Bertrand Arnulf
Research Article November 19 2024
Bivalent CD47 Immunotoxin for Targeted Therapy of T-Cell Acute Lymphoblastic Leukemia
Research Article November 19 2024
Development of ALL-Hematotox (ALL-HT): Predicting post CAR T-cell hematotoxicity in B-cell acute lymphoblastic leukemia
Research Article November 19 2024
Preclinical efficacy of CDK7 inhibitor-based combinations against myeloproliferative neoplasms transformed to AML
Warren Fiskus,Christopher P Mill,Prithviraj Bose,Lucia Masarova,Naveen Pemmaraju,Andrew Dunbar,Christine Birdwell,John A Davis,Kaberi Das,Hanxi Hou,Taghi Manshouri,Antrix Jain,Anna Malovannaya,Kevin Philip,Noor Alhamadani,Alicia Matthews,Katie Lin,Lauren Flores,Sanam Loghavi,Courtney D. DiNardo,Xiaoping Su,Raajit K. Rampal,Kapil N Bhalla
Review Article November 14 2024
Approaching a therapeutic inflection point for FLT3-mutated AML
Review Article November 14 2024
Imetelstat: A new addition to the Therapeutic Landscape of Lower-Risk MDS
Research Article November 14 2024
Ferroptosis regulates hemolysis in stored murine and human red blood cells
Angelo D'Alessandro,Gregory R Keele,Ariel M Hay,Travis Nemkov,Eric J Earley,Daniel Stephenson,Matthew Vincent,Xutao Deng,Mars Stone,Monika Dzieciatkowska,Kirk C Hansen,Steven H Kleinman,Steven L Spitalnik,Nareg H Roubinian,Philip J Norris,Michael P Busch,Grier P Page,Brent Stockwell,Gary A Churchill,James C Zimring
Research Article November 6 2024
Acute Promyelocytic Leukemia: Long-Term Outcomes from the HARMONY Project
Maria Teresa Voso,Luca Guarnera,Sören Lehmann,Konstanze Döhner,Hartmut Döhner,Uwe Platzbecker,Nigel H. Russell,Richard James Dillon,Ian Thomas,Gert J Ossenkoppele,Torsten Haferlach,Marco Vignetti,Edoardo La Sala,Alfonso Piciocchi,Paola Fazi,Ángela Villaverde Ramiro,Laura Tur Giménez,Carmelo Gurnari,Lars Bullinger,Jesus M. Hernandez
Research Article November 1 2024
Safety and efficacy of pegcetacoplan treatment for cold agglutinin disease and warm antibody autoimmune hemolytic anemia
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