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Brief Report February 28 2025
The bone marrow NK cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy
Charlotte L.B.M. Korst,Sabrin Tahri,Carolien Duetz,Wassilis S.C. Bruins,A. Vera de Jonge,Madelon M.E. de Jong,Cathelijne Fokkema,Febe Smits,Kaz Groen,Christie P.M. Verkleij,Kristine A. Frerichs,Natalie Papazian,Mark van Duin,Gregory van Beek,Remco Hoogenboezem,Thomas Baardemans,Giada Dal Collo,Elodie C.G. Stoetman,Meliha Cosovic,Inoka Twickler,Rosa Rentenaar,Merve Eken,Paola M. Homan-Weert,Elona Saraci,Mattia D'Agostino,Vincent H.J. van der Velden,Mathijs Arnoud Sanders,Francesca Gay,Annemiek Broijl,Philippe Moreau,Pieter Sonneveld,Sonja Zweegman,Tuna Mutis,Tom Cupedo,Niels W.C.J. van de Donk
Review Article February 28 2025
Exploring the thrombus niche: Lessons learned and potential therapeutic opportunities
Review Article February 28 2025
The Future of Follicular Lymphoma Management: Strategies on the Horizon
Research Article February 27 2025
Decoding functional hematopoietic progenitor cells in the adult human lung
Research Article February 26 2025
Integrated cross-linking by TG2 and FXIII generates hepatoprotective fibrin(ogen) deposits in injured liver
Research Article February 26 2025
Histo-blood group ABO system transferase plasma levels and risk of future venous thromboembolism: The HUNT Study
Research Article February 26 2025
Ibrutinib Lead-in followed by Venetoclax Plus Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia - SAKK 34/17
Research Article February 26 2025
STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia
Research Article February 26 2025
Up-front Blinatumomab Improves MRD Clearance and Outcome in Adult Ph− B-lineage ALL: the GIMEMA LAL2317 Phase 2 Study
Renato Bassan,Sabina Chiaretti,Irene Della Starza,Alessandra Santoro,Orietta Spinelli,Manuela Tosi,Loredana Elia,Deborah Cardinali,Maria Stefania De Propris,Matteo Piccini,Federico Lussana,Mario Annunziata,Patrizia Chiusolo,Patrizia Zappasodi,Erika Borlenghi,Matteo Leoncin,Catello Califano,Monica Bocchia,Francesco Di Raimondo,Francesco Grimaldi,Mario Tiribelli, MD,Anna Candoni,Albana Lico,Ernesta Audisio,Monia Lunghi,Anna Maria Mianulli,Mariangela Di Trani,Valentina Arena,Monica Messina,Alfonso Piciocchi,Paola Fazi,Alessandro Rambaldi,Robin Foà
Research Article February 26 2025
A CEBPB/IL-1β/TNF-α Feedback Loop Drives Drug Resistance to Venetoclax and MDM2 Inhibitors in Monocytic Leukemia
Basil Allen,Daniel Bottomly,Thomas Köhnke,Anthony Wang,Hsin-Yun Lin,Kara Johnson,Isabel Kenna,Anastatia Streltsova,Emma Martin,Reid Chen,Lindsey Savoy,Nicola Long,Peter Ryabinin,Stephen E Kurtz,Christopher A Eide,Amy Carlos,Andy Kaempf,Tingting Liu,Cristina E. Tognon,Robert Searles,Paul D. Piehowski,Sara J.C. Gosline,Anupriya Agarwal,Bill H Chang,Michelle Barton,Brian J Druker,Shannon K. McWeeney,Ravindra Majeti,Jeffrey W. Tyner,Haijiao Zhang
Research Article February 26 2025
The MURANO study: final analysis and retreatment/crossover substudy results of VenR for patients with relapsed/refractory CLL
Arnon P. Kater,Rosemary Anne Harrup,Thomas J Kipps,Barbara Eichhorst,Carolyn Owen,Sarit E. Assouline,Nicole Lamanna,Tadeusz Robak, Prof.,Javier de la Serna,Ulrich Jaeger,Guillaume Cartron,Marco Montillo,Clemens Mellink,Anton W. Langerak,Brenda Chyla,Relja Popovic,Yanwen Jiang,Rosemary Millen,Marcus Lefebure,Maria Thadani-Mulero,Michelle Boyer,John F Seymour
Research Article February 26 2025
NOTCH1 dimeric signaling is essential for T-cell leukemogenesis and leukemia maintenance
Research Article February 26 2025
cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant Conditioning
Research Article February 26 2025
Aberrant single-cell phenotype and clinical implications of genotypically defined polyclonal plasma cells in myeloma
Matteo Claudio Da Viá,Francesca Lazzaroni,Antonio Matera,Alessio Marella,Akihiro Maeda,Claudio De Magistris,Loredana Pettine,Antonio Giovanni Solimando,Vanessa Desantis,Giuseppe M Peretti,Laura Mangiavini,Riccardo Giorgino,Sonia Fabris,Stefania Pioggia,Alfredo Marchetti,Marzia Barbieri,Silvia Lonati,Alessandra Cattaneo,Marta Tornese,Margherita Scopetti,Emanuele Calvi,Nayyer Latifinavid,Giancarlo Castellano,Federica Torricelli, Dr,Antonino Neri,Cathelijne Fokkema,Tom Cupedo,Marta Lionetti,Francesco Passamonti,Niccolò Bolli
Research Article February 26 2025
A First-in-Class JAK/ROCK Inhibitor, Rovadicitinib, for Glucocorticoid-Refractory or -Dependent Chronic GVHD
Research Article February 26 2025
Magrolimab plus azacitidine vs physician's choice for untreated TP53-mutated acute myeloid leukemia: the ENHANCE-2 study
Joshua F. Zeidner,David A. Sallman,Christian Récher,Naval G. Daver,Anskar YH Leung,Devendra K. Hiwase,Marion Subklewe,Thomas Pabst,Pau Montesinos,Richard A Larson,Lindsay Wilde,Anoop K. Enjeti,Ichiro Kawashima,Cristina Papayannidis,Jenny O'Nions,Lisa Johnson,Mei Dong,Julie Huang,Taravat Bagheri,Gal Hacohen-Kleiman,Calvin Lee,Paresh Vyas
Research Article February 26 2025
Venetoclax and Decitabine vs Intensive Chemotherapy as Induction for Young Patients with Newly Diagnosed AML
Research Article February 26 2025
Sustained bone marrow and imaging MRD negativity for 3 years drives discontinuation of maintenance post ASCT in myeloma
Evangelos Terpos,Panagiotis Malandrakis,Ioannis Ntanasis-Stathopoulos,Ioannis V Kostopoulos,Evangelos Eleutherakis-Papaiakovou,Nikolaos Kanellias,Vassiliki Spiliopoulou,Magdalini Migkou,Despina V Fotiou,Foteini Theodorakakou,Efstathios Kastritis,Maria Gavriatopoulou,Ourania Tsitsilonis,Meletios-Athanasios A. Dimopoulos
Research Article February 20 2025
Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease
Research Article February 20 2025
Surface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL
Lucien Courtois,Antoine Pinton,Aurelie Cabannes-Hamy,Mathieu Simonin,Guillaume P. Andrieu,Mélodie Queri,Charlotte Smith,Guillaume Charbonnier,Marie-Emilie Dourthe,Marianne Courgeon,Grégoire Huré,Nicolas Gaidot,Elizabeth A. Macintyre,Hervé Dombret,André Baruchel,Nicolas Boissel,Aurore Touzart,Ludovic Lhermitte,Philippe Rousselot,Vahid Asnafi
Review Article February 19 2025
Clinical-genomic profiling of MDS to inform allo-HSCT:Recommendations from an international panel on behalf of the EBMT
Carmelo Gurnari,Marie Robin,Lionel Adès,Mahmoud Aljurf,Antonio M Almeida,Fernando Barroso Duarte,Elsa Bernard,Corey S. Cutler,Matteo Giovanni Della Porta,Theo M de Witte,Amy E. DeZern,Joanna Drozd-Sokolowska,Eric J Duncavage,Pierre Fenaux,Nico Gagelmann,Guillermo Garcia-Manero,Claudia Haferlach,Torsten Haferlach,Robert P. Hasserjian,Eva S Hellstrom-Lindberg,Meagan A Jacoby,Austin G Kulasekararaj,R. Coleman Lindsley,Jaroslaw P. Maciejewski,Hideki Makishima,Luca Malcovati,Moshe Mittelman,Anders Eivind Myhre,Seishi Ogawa,Francesco Onida,Elli Papaemmanuil,Jakob R Passweg,Uwe Platzbecker,Lisa Pleyer,Kavita Raj,Valeria Santini,Anna Sureda,Magnus Tobiasson,Maria Teresa Voso,Ibrahim Yakoub-Agha,Amer M. Zeidan,Matthew J Walter,Nicolaus Kröger,Donal P McLornan,Mario Cazzola
Review Article February 12 2025
Emerging biomarkers for CD3×CD20 bispecific antibodies in lymphoma
Research Article February 12 2025
Outcomes Among Adult Recipients of CAR T-cell Therapy for Burkitt Lymphoma
Laura Samples,Hossein Sadrzadeh,Matthew J. Frigault,Caron A. Jacobson,Mehdi Hamadani,Ashwath Gurumurthi,Paolo Strati,Roni Shouval,Ariela Noy,Peter A Riedell,Saurabh Dahiya,David G Maloney,Brian G Till,Alexandre V. Hirayama,Jordan Gauthier,Ajay K Gopal,Stephen D Smith,Christina Poh,Ryan C Lynch,Chaitra Ujjani,Mengyang Di,Vikram Raghunathan,Mehrdad Shakib-Azar,Kikkeri N Naresh,Ted A Gooley,Jean A. Yared,Michael D Jain,Frederick L Locke,Lori A. Leslie,Narendranath Epperla,Monalisa Ghosh,Alan P Skarbnik,Brian T. Hill,Manali Kamdar,Valentín Ortiz-Maldonado,Nuria Martínez-Cibrian,Leyla Shune,Mazyar Shadman
Research Article February 12 2025
Three-year follow-up analysis of first-line axicabtagene ciloleucel in high-risk large B-cell lymphoma (ZUMA-12)
Research Article February 10 2025
17(R)-RESOLVIN D1 PROTECTS AGAINST SICKLE CELL-RELATED INFLAMMATORY CARDIOMYOPATHY IN HUMANIZED MICE
Research Article February 10 2025
N-homocysteinylation of β-arrestins biases GPCR signaling and promotes platelet activation
Research Article February 7 2025
Targeting cell surface VISTA expression on allospecific naïve T cells promotes tolerance
Brent H Koehn,Elizabeth C Nowak,Sladjana Skopalja-Gardner,Asim Saha,Michael C. Zaiken,Jeremy R Allred,Yiyung Peng,Wilson Lloyd Davis, III,Isabelle Le Mercier,Nicholas Schwertner,Michael J Molloy,Jay Rothstein,Catherine Carriere,Megan J Riddle,Cindy Eide,Jakub Tolar,Angela Panoskaltsis-Mortari,Kyle D Smith,Keli L. Hippen,Tae Kon Kim,Randolph J Noelle,Bruce R Blazar
Brief Report February 7 2025
Venetoclax plus Daunorubicin and Cytarabine for Newly Diagnosed Acute Myeloid Leukemia: Results of a Phase 1b Study
Ioannis Mantzaris,Mendel Goldfinger,Matan Uriel,Aditi Shastri,Nishi Shah,Kira Gritsman,Noah Kornblum,Lauren C Shapiro,Alejandro Sica,Anne Munoz,Nicole Chambers,Aradhika Dhawan,Jhannine Alyssa Verceles,Karen Fehn,Balda Tirone,Lamisha Shah,Shaunmonique Clark,Chenxin Zhang,Mimi Y Kim,Dennis L Cooper,Amit Verma,Marina Y. Konopleva,Eric J Feldman
Brief Report February 7 2025
The JAK2 46/1 haplotype influences PD-L1 expression.
Research Article February 6 2025
Targeting Caseinolytic Mitochondrial Matrix Peptidase, a Novel Contributor to High-risk Behavior, in Multiple Myeloma
Review Article February 6 2025
Impact of new medications on the treatment of Immune TTP
Review Article February 5 2025
EMZL at various sites: learning from each other
Research Article February 5 2025
PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells
Lingli He,Ting Zhao,Wei Zhong Leong,Azeem Sharda,Christina Mayerhofer,Shenglin Mei,Gracia M. Bonilla,Juan Bautista Menendez-Gonzalez,Karin Gustafsson,Tsuyoshi Fukushima,Trine A. Kristiansen,Ji-Won Lee,Yanxin Xu,Lei Chen,Jun Xia,Luis Angel Orozco,Bogdan Budnik,Ruslan Sadreyev,Zhixun Dou,David B. Sykes,David T Scadden
Research Article February 3 2025
Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD
Research Article February 3 2025
Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface
Zohreh Mansoori Moghadam,Bei Zhao,Candice Raynaud, RWTH University Hospital,Valentina Strohmeier,Jana Neuber,Anne Kathrin Lösslein,Sabrina Qureshi,Vitka Gres,Tara Ziegelbauer,Sebastian Baasch,Christoph Schell,Klaus Warnatz,Naohiro Inohara,Gabriel Nunez,Thomas Clavel,Stephan Patrick Rosshart,Julia Kolter,Philipp Henneke
Research Article February 3 2025
IL-10 from tumoral B cells modulates the diffuse large B-cell lymphoma microenvironment and response to immunotherapy
Marcos Garcia-Lacarte,Sara C Grijalba,Javier Melchor Sánchez,Marién Pascual,Enrique Goñi,Iñigo Clemente-Larramendi,Sandra Morales-Sánchez,Maria A Burrell,Oscar Blanco,Adrián Arnaiz-Leché,Blanca S Berrozpe,Maria Amann,Christian Klein,Pablo Umaña,Miguel Angel Canales,José Ángel Martínez-Climent,Juan Jose Lasarte,Pablo Sarobe,Francisco J Novo,Sergio Roa
Review Article February 3 2025
How I approach pharmacological thromboprophylaxis in children
Review Article January 30 2025
Sickle Cell Trait Does Not Cause "Sickle Cell Crisis" Leading to Exertion-Related Death: A Systematic Review
Research Article January 30 2025
MRD-guided zanubrutinib, venetoclax and obinutuzumab in relapsed CLL: primary endpoint analysis from the CLL2-BZAG trial
Moritz Fürstenau,Sandra Robrecht,Christof Schneider,Eugen Tausch,Adam Giza,Matthias Ritgen,Jörg T Bittenbring,Holger Hebart,Björn Schöttker,Anna Lena Lena Illert,Ullrich Graeven,Andrea Stoltefuss,Bernhard Heinrich,Robert Eckert,Anna-Maria Fink,Janina Stumpf,Kirsten Fischer,Othman Al-Sawaf,Florian Simon,Fanni Kleinert,Jonathan Weiss,Karl-Anton Kreuzer,Anke Schilhabel,Monika Brüggemann,Petra Langerbeins,Stephan Stilgenbauer,Barbara Eichhorst,Michael J Hallek,Paula Cramer
Research Article January 27 2025
Protection of β2GPI-Deficient Mice from Thrombosis Reflects a Defect in PAR3-facilitated Platelet Activation
Review Article January 27 2025
Platelet activation and signaling in thrombus formation
Review Article January 27 2025
Factor XIII: Driving (Cross-)Links in Hemostasis, Thrombosis, and Disease
Research Article January 27 2025
Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response
Sravya Tumuluru,James K. Godfrey,Alan Cooper,Jovian Yu,Xiufen Chen,Brendan MacNabb,Girish Venkataraman,Yuanyuan Zha,Benedikt Pelzer,Joo Y. Song,Gerben Duns,Brian Sworder,Sandeep S Raj,Christopher R Bolen,Elicia Penuel,Ekaterina Postovalova,Nikita Kotlov,Aleksander Bagaev,Nathan H Fowler,Roni Shouval,Sonali M Smith,Ash A Alizadeh,Christian Steidl,Justin P. Kline
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