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Luca Bertamini
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Journal Articles

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

Luca Bertamini, Jean-Baptiste Alberge, David Jungpa Lee, Habib El-Khoury, Sungjae Kim, Grace Fleming, Ciara Suen Marie Murphy, Julia Colchie, Maya I Davis, Jacqueline Perry, Elizabeth D Lightbody, Sabine Allam, Lindokuhle N Goqwana, Vinitha Philip, Natalie Anne Smyth, NA, Dhananjay Sakrikar, Mark C Perkins, Stephen Harding, Derek Troske, Gad Getz, Elizabeth W Karlson, Nikhil C. Munshi, Kenneth C. Anderson, Lorenzo Trippa, Catherine R Marinac, Wenlong Carl Chen, Maureen Joffe, Irene M Ghobrial
Journal: Blood
Blood blood.2024026078.
https://doi.org/10.1182/blood.2024026078
Published: 2024
Includes: Supplemental data
Journal Articles

Deep Learning Unveils Characteristics of Immune B Cell Aging in >17,000 Samples and Identifies Changes in the Immunoglobulin Repertoire Distribution and the Development of Monoclonal Gammopathy

Floris Chabrun, Jean-Baptiste Alberge, Sabine Allam, Jacqueline F Perry, Habib El-Khoury, David J Lee, Michael Timonian, Luca Bertamini, Hadley Barr, Grace Fleming, Joseph Casey Flinn, Ciara Murphy, Sofia Wallin, Hiba Hussain, Elizabeth D. Lightbody, Sungjae Kim, Mark C Perkins, Stephen J. Harding, Dhananjay Sakrikar, Romanos Sklavenitis Pistofidis, Kenneth C. Anderson, Omar Nadeem, Elizabeth K. O'Donnell, Yuxin Liu, Wenlong Chen, Maureen Joffe, Benjamin Levine Ebert, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 4984.
https://doi.org/10.1182/blood-2024-194368
Published: 2024
Journal Articles

Circulating Tumor Cells As a Biomarker to Identify High-Risk Transplant Eligible Myeloma Patients Treated with Bortezomib, Lenalidomide and Dexamethasone with or without Daratumumab during Induction/Consolidation, and Lenalidomide with or without Daratumumab during Maintenance: Results from the Perseus Study

Luca Bertamini, Cathelijne Fokkema, Paula Rodríguez-Otero, Mark van Duin, Niels W.C.J. Van De Donk, Mattia D'Agostino, Evangelos Terpos, Diego Vieyra, Ricardo M. Attar, Anna Sitthi-Amorn, Robin Carson, Michel Delforge, Christoph Driessen, Roman Hajek, Mario Boccadoro, Hermann Einsele, Annette Vangsted, Vincent H.J. Van Der Velden, Fredrik Schjesvold, Artur Jurczyszyn, Meral Beksac, Andrew Spencer, Annemiek Broijl, Tom Cupedo, Philippe Moreau, Pieter Sonneveld
Journal: Blood
Blood (2024) 144 (Supplement 1): 487.
https://doi.org/10.1182/blood-2024-199550
Published: 2024
Journal Articles

Early Serum Protein Clonal Dynamics Preceding Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma Years before Diagnosis

Sabine Allam, Floris Chabrun, Jean-Baptiste Alberge, Grace Fleming, Sungjae Kim, Yoshinobu Konishi, Habib El-Khoury, Luca Bertamini, Sofia Wallin, Joseph Casey Flinn, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C Perkins, Stephen J. Harding, Romanos Sklavenitis-Pistofidis, Paolo Ghia, Catherine R. Marinac, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3279.
https://doi.org/10.1182/blood-2024-203937
Published: 2024
Journal Articles

Tumor-Intrinsic and Immune Predictors of Response to Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Michelle P. Aranha, Omar Nadeem, Robert A. Redd, Michael Timonian, Sophie Magidson, Elizabeth D. Lightbody, Jean-Baptiste Alberge, Ting Wu, Junko Tsuji, Luca Bertamini, Ankit K. Dutta, Habib El-Khoury, Mark Bustoros, Jacob Laubach, Giada Bianchi, Elizabeth K. O'Donnell, Kenneth C. Anderson, Gad Getz, Lorenzo Trippa, Paul G. Richardson, Romanos Sklavenitis-Pistofidis, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1928.
https://doi.org/10.1182/blood-2024-203684
Published: 2024
Journal Articles

Novel Non-Coding Candidate Drivers of Multiple Myeloma Linked to Plasma Cell Tumor Biology and B Cell Development

Jean-Baptiste Alberge, Ankit K. Dutta, Andrea Poletti, Oliver Priebe, Tim H.H. Coorens, Elizabeth D. Lightbody, Rosa Toenges, Xavi Loinaz, Sofia Wallin, Andrew Dunford, Cody J. Boehner, Erica M. Horowitz, Nang Kham Su, Hadley Barr, Laura Hevenor, Katherine Towle, Rashmika Beesam, Jenna D. Beckwith, Jacqueline Perry, David M. Cordas dos Santos, Luca Bertamini, Kirsten Kübler, Carolina Terragna, Elena Zamagni, Julian Hess, Romanos Sklavenitis-Pistofidis, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1894.
https://doi.org/10.1182/blood-2024-205523
Published: 2024
Journal Articles

A 1,000-Genome Map for Multiple Myeloma and Its Precursor Stages, and Its Impact on Clinical Outcome

Jean-Baptiste Alberge, Ankit K. Dutta, Andrea Poletti, Tim H.H. Coorens, Elizabeth D. Lightbody, Rosa Toenges, Xavi Loinaz, Sofia Wallin, Andrew Dunford, Oliver Priebe, Cody J. Boehner, Erica M. Horowitz, Nang Kham Su, Hadley Barr, Laura Hevenor, Katherine Towle, Rashmika Beesam, Jenna D. Beckwith, Jacqueline Perry, David M. Cordas dos Santos, Luca Bertamini, Patricia Greipp, Kirsten Kübler, Peter F. Arndt, Carolina Terragna, Elena Zamagni, Julian Hess, Romanos Sklavenitis-Pistofidis, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2024-203517
Published: 2024
Journal Articles

High-Throughput Plasma Proteomics to Define the Precursor Multiple Myeloma Proteome and Identify Candidate High-Risk Disease Biomarkers of Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Habib El-Khoury, Ankit K. Dutta, Hadley Barr, Namrata Udeshi, Luca Bertamini, Nang Kham Su, Cody J. Boehner, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Annie Cowan, Catherine R. Marinac, Michael Gillette, Steven A. Carr, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 334.
https://doi.org/10.1182/blood-2023-189091
Published: 2023
Journal Articles

Multi-Center Clinical Validation of a Mass Spectrometry Immunoassay for the Diagnosis and Monitoring of Multiple Myeloma and Associated Disorders

Oscar Berlanga, Jane Birtwistle, Syreeta Allen, Gemma Malin, Cristina Simion, Habib El-Khoury, Julia Colchie, Luca Bertamini, Grace Fleming, Erica M. Horowitz, Irene M. Ghobrial, Kaleb B McLendon, John Roback, Andrew S Neish, Sarah K Grewal, Gabriella Lakos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3667.
https://doi.org/10.1182/blood-2023-189050
Published: 2023
Journal Articles

Persistence of Monoclonal Gammopathies in Serial Samples from a US Population-Based Screening Study

Habib El-Khoury, Luca Bertamini, Jean-Baptiste Alberge, David J. Lee, Ciara Murphy, Grace Fleming, Christian J. Cea-Curry, Maya I. Davis, Jacqueline Perry, Elizabeth D. Lightbody, Dhananjay Sakrikar, Derek Troske, David Barnidge, Mark C. Perkins, Stephen Harding, Gad Getz, Catherine R. Marinac, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 10101–10103.
https://doi.org/10.1182/blood-2022-169380
Published: 2022
Journal Articles

Abnormal Free Light Chains in Individuals with African Ancestry Screened for Monoclonal Gammopathy: Definition of New Reference Range Accounting for Renal Function and Race

Luca Bertamini, Jean-Baptiste Alberge, Habib El-Khoury, David J. Lee, Ciara Murphy, Grace Fleming, Maya I. Davis, Jacqueline Perry, Christian J. Cea-Curry, Audrey Pentz, Thulisile Hlubi, Natalie Smyth, D.J. Sakrikar, Mark C. Perkins, Stephen Harding, Derek Troske, Gad Getz, Timothy R. Rebbeck, Maureen Joffe, Catherine R. Marinac, Nelson Leung, Carl Wenlong Chen, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 10005–10006.
https://doi.org/10.1182/blood-2022-164436
Published: 2022
Journal Articles

Prevalence of Monoclonal Gammopathies Detected By Mass Spectrometry and Their Risk Factors Among Black Africans in South Africa

David J. Lee, Habib El-Khoury, Luca Bertamini, Jean-Baptiste Alberge, Maya I. Davis, Jacqueline Perry, Dhananjay Sakrikar, David Barnidge, Mark C. Perkins, Stephen Harding, Derek Troske, Audrey Pentz, Thulisile Hlubi, Natalie Smyth, Anna Cowan, Angela C. Tramontano, Gad Getz, Timothy R. Rebbeck, Maureen Joffe, Wenlong Carl Chen, Catherine R. Marinac, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 7228–7229.
https://doi.org/10.1182/blood-2022-167268
Published: 2022
Journal Articles

Survival Analysis of Newly Diagnosed Transplant-Eligible Multiple Myeloma Patients in the Randomized Forte Trial

Francesca Gay, MD, Pellegrino Musto, Delia Rota Scalabrini, Monica Galli, Angelo Belotti, Elena Zamagni, Luca Bertamini, MD, Renato Zambello, Micol Quaresima, Giovanni De Sabbata, Giuseppe Pietrantuono, Mattia D'Agostino, MD, Daniela Oddolo, Andrea Capra, Anna Marina Liberati, Salvatore Palmieri, Franco Narni, Massimo Offidani, Michele Cavo, Mario Boccadoro
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–37.
https://doi.org/10.1182/blood-2020-136907
Published: 2020
Journal Articles

Poor Prognosis of Multiple Myeloma Predicted By High Levels of Circulating Plasma Cells Is Independent from Other High-Risk Features but Is Modulated By the Achievement of Minimal Residual Disease Negativity

Luca Bertamini, MD, Mariella Grasso, Mattia D'Agostino, MD, Anna Pascarella, Patrizia Tosi, Federico Monaco, Francesco Pisani, Paola Bertazzoni, Milena Gilestro, Andrea Capra, Piero Galieni, Ombretta Annibali, Vincenzo Pavone, Stefano Molica, MD, Sonia Ronconi, Paola Tacchetti, Pellegrino Musto, Francesca Gay, MD, Mario Boccadoro, Stefania Oliva
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-137075
Published: 2020
Journal Articles

Integrative Analysis of Baseline Prognostic Features and Achievement of Minimal Residual Disease Negativity As Predictors of Early Relapse in Transplant-Eligible Multiple Myeloma Patients

Francesca Gay, MD, Gian Maria Zaccaria, Massimo Offidani, Federico Vozella, Paolo Becco, Angelo Belotti, Andrea Capra, Monica Galli, Fortunato Morabito, Luca Bertamini, Francesco Pisani, Piero Galieni, Rita Rizzi, Alessandro Gozzetti, Norbert Pescosta, Luca De Rosa, Franco Narni, Milena Gilestro, Salvatore Palmieri, Michele Cea, Patrizia Tosi, Nicola Giuliani, Pellegrino Musto, Michele Cavo, Mario Boccadoro
Journal: Blood
Blood (2019) 134 (Supplement_1): 605.
https://doi.org/10.1182/blood-2019-125588
Published: 2019
Journal Articles

Mitoxantrone, Etoposide and Cytarabine (MEC) Can Induce Deep Complete Remission and Is an Effective Bridge Therapy to Allotransplantation (SCT) in Refractory/Relapsed Acute Myeloid Leukemia (AML) Patients

Giovanni Marconi, Annalisa Talami, Maria Chiara Abbenante, Stefania Paolini, MD PhD, Chiara Sartor, Sarah Parisi, Stefano de Polo, Jacopo Nanni, MD, Luca Bertamini, MD, Simone Ragaini, Matteo Olivi, Maria Chiara Fontana, MSc, Maria Teresa Bochicchio, Emanuela Ottaviani, Carmen Baldazzi, Nicoletta Testoni, BSc, Giovanni Martinelli, Michele Cavo, MD, Cristina Papayannidis, Antonio Curti
Journal: Blood
Blood (2018) 132 (Supplement 1): 4036.
https://doi.org/10.1182/blood-2018-99-113036
Published: 2018
Journal Articles

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Maria Chiara Fontana, MSc, Matteo Olivi, Giovanni Marconi, Mariachiara Abbenante, MD, Eugenio Fonzi, PhD, Stefania Paolini, MD PhD, Chiara Sartor, Sarah Parisi, Samantha Bruno, Martina Pazzaglia, Stefano De Polo, Jacopo Nanni, MD, Luca Bertamini, MD, Simone Ragaini, Annalisa Talami, Maria Teresa Bochicchio, Emanuela Ottaviani, Anna Ferrari, PhD, Carmen Baldazzi, Nicoletta Testoni, BSc, Torsten Haferlach, MD, Robert Kralovics, PhD, Jelena D. Milosevic Feenstra, PhD, Simona Soverini, PhD, Giovanni Martinelli, Antonio Curti, Michele Cavo, MD, Cristina Papayannidis, Giorgia Simonetti, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2748.
https://doi.org/10.1182/blood-2018-99-118183
Published: 2018
Journal Articles

Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Patients with Coronary Artery Disease and in Centenarians. Further Clues Linking Chip with Cardiovascular Risk

Luca Bertamini, MD, Claudia Sala, Nicola Martinelli, MD PhD, Cristina Papayannidis, MD PhD, Cristina Giuliani, Giovanni Malerba, Paolo Garagnani, Oliviero Olivieri, Giovanni Martinelli, MD, Claudio Franceschi, Domenico Girelli, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1144.
https://doi.org/10.1182/blood.V130.Suppl_1.1144.1144
Published: 2017
Journal Articles

MHC-I Antigen Presentation Role in Immune Escape of Acute Myeloid Leukemia with High Burden of Genomic Aberration

Giovanni Marconi, MD, Maria Chiara Fontana, MSc, Eugenio Fonzi, PhD, Cristina Papayannidis, MD, Mariachiara Abbenante, MD, Emanuela Ottaviani, Nicoletta Testoni, BSc, Giorgia Simonetti, PhD, Antonella Padella, Chiara Sartor, Carmen Baldazzi, Jacopo Nanni, MD, Luca Bertamini, MD, Andrea Ghelli Luserna Di Rora, Valentina Robustelli, Martina Pazzaglia, Elena Tenti, PhD, Sarah Parisi, MD PhD, Giovanni Martinelli, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3958.
https://doi.org/10.1182/blood.V130.Suppl_1.3958.3958
Published: 2017