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Erica M. Horowitz
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Journal Articles

Single-Cell Profiling of ~1.7 Million Plasma Cells across >250 Individuals Reveals Transcriptional Signatures of Progression and Clonal Expansion in Multiple Myeloma and Its Precursor Stages

Junko Tsuji, Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Ting Wu, Michael P. Agius, Danielle T. Firer, Mahshid Rahmat, Hadley Barr, Yoshinobu Konishi, Ankit K. Dutta, Jean-Baptiste Alberge, Nang Kham Su, Cody J. Boehner, Michelle P. Aranha, Laura Hevenor, Katherine Towle, Erica M. Horowitz, Maya Davis, Jacqueline F Perry, Francois Aguet, Ruitong Li, Sungjae Kim, Nicholas J. Haradhvala, Rebecca Boiarsky, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 4637.
https://doi.org/10.1182/blood-2024-206540
Published: 2024
Journal Articles

Comprehensive Characterization of the Plasma Proteome of Multiple Myeloma and Its Precursor Conditions and Identification of a Proteomic Signature to Improve Risk Prediction of Disease Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Namrata Udeshi, Romanos Sklavenitis-Pistofidis, Ankit K. Dutta, Ting Wu, Junko Tsuji, Habib El-Khoury, Hadley Barr, Sarah Nersesian, Nang Kham Su, Cody J. Boehner, Michael P. Agius, Michelle P. Aranha, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Daniel Heilpern-Mallory, Erica M. Horowitz, Jacqueline F Perry, Maya Davis, Kelly Walsh, Annie Cowan, John E. Ready, Catherine R. Marinac, Gad Getz, Michael Gillette, Steven A. Carr, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1903.
https://doi.org/10.1182/blood-2024-209286
Published: 2024
Journal Articles

Novel Non-Coding Candidate Drivers of Multiple Myeloma Linked to Plasma Cell Tumor Biology and B Cell Development

Jean-Baptiste Alberge, Ankit K. Dutta, Andrea Poletti, Oliver Priebe, Tim H.H. Coorens, Elizabeth D. Lightbody, Rosa Toenges, Xavi Loinaz, Sofia Wallin, Andrew Dunford, Cody J. Boehner, Erica M. Horowitz, Nang Kham Su, Hadley Barr, Laura Hevenor, Katherine Towle, Rashmika Beesam, Jenna D. Beckwith, Jacqueline Perry, David M. Cordas dos Santos, Luca Bertamini, Kirsten Kübler, Carolina Terragna, Elena Zamagni, Julian Hess, Romanos Sklavenitis-Pistofidis, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1894.
https://doi.org/10.1182/blood-2024-205523
Published: 2024
Journal Articles

A 1,000-Genome Map for Multiple Myeloma and Its Precursor Stages, and Its Impact on Clinical Outcome

Jean-Baptiste Alberge, Ankit K. Dutta, Andrea Poletti, Tim H.H. Coorens, Elizabeth D. Lightbody, Rosa Toenges, Xavi Loinaz, Sofia Wallin, Andrew Dunford, Oliver Priebe, Cody J. Boehner, Erica M. Horowitz, Nang Kham Su, Hadley Barr, Laura Hevenor, Katherine Towle, Rashmika Beesam, Jenna D. Beckwith, Jacqueline Perry, David M. Cordas dos Santos, Luca Bertamini, Patricia Greipp, Kirsten Kübler, Peter F. Arndt, Carolina Terragna, Elena Zamagni, Julian Hess, Romanos Sklavenitis-Pistofidis, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2024-203517
Published: 2024
Journal Articles

High-Throughput Plasma Proteomics to Define the Precursor Multiple Myeloma Proteome and Identify Candidate High-Risk Disease Biomarkers of Progression

Elizabeth D. Lightbody, D. R. Mani, Hasmik Keshishian, Habib El-Khoury, Ankit K. Dutta, Hadley Barr, Namrata Udeshi, Luca Bertamini, Nang Kham Su, Cody J. Boehner, Laura Hevenor, Katherine Towle, Grace Fleming, Christian Cea-Curry, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Annie Cowan, Catherine R. Marinac, Michael Gillette, Steven A. Carr, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 334.
https://doi.org/10.1182/blood-2023-189091
Published: 2023
Journal Articles

Large-Scale Characterization and Functional Assessment of Adaptive Immunity in Patients with MGUS and SMM Reveals Significant Defects

Michelle P. Aranha, Romanos Sklavenitis-Pistofidis, Yoshinobu Konishi, Ting Wu, Hong Yue, Elizabeth D. Lightbody, Mahshid Rahmat, Michael Timonian, Daniel L. Mallory, Michael P. Agius, Shohreh Varmeh, Nang Kham Su, Jacqueline Perry, Erica M. Horowitz, Maya Davis, Anna Justis, Radosław P. Nowak, Mark Hamilton, Daniel Auclair, Catherine R. Marinac, Eric Fischer, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 2548.
https://doi.org/10.1182/blood-2023-178062
Published: 2023
Journal Articles

Multi-Center Clinical Validation of a Mass Spectrometry Immunoassay for the Diagnosis and Monitoring of Multiple Myeloma and Associated Disorders

Oscar Berlanga, Jane Birtwistle, Syreeta Allen, Gemma Malin, Cristina Simion, Habib El-Khoury, Julia Colchie, Luca Bertamini, Grace Fleming, Erica M. Horowitz, Irene M. Ghobrial, Kaleb B McLendon, John Roback, Andrew S Neish, Sarah K Grewal, Gabriella Lakos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3667.
https://doi.org/10.1182/blood-2023-189050
Published: 2023
Journal Articles

Single-Cell RNA Sequencing of Circulating Tumor Cells in Precursor Myeloma Patients Reveals Mechanisms of Disease Dissemination

Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Danielle T. Firer, Junko Tsuji, Mike P. Agius, Ankit K. Dutta, Ting Wu, Hadley Barr, Sungjae Kim, Tim Coorens, Jean-Baptiste Alberge, Michelle P. Aranha, Nicholas J Haradhvala, Nang Kham Su, Cody J. Boehner, Kelly Walsh, Mahshid Rahmat, Yoshinobu Konishi, Laura Hevenor, Katherine Towle, Erica M. Horowitz, Jacqueline Perry, Grace Fleming, Habib El-Khoury, Michael Vinyard, Annie Cowan, Daniel Auclair, John E. Ready, Catherine R. Marinac, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 872.
https://doi.org/10.1182/blood-2023-189760
Published: 2023