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Journal Articles

DLBclass: A Probabilistic Molecular Classifier to Guide Clinical Investigation and Practice in DLBCL

Björn Chapuy, Timothy R. Wood, Chip Stewart, Andrew J. Dunford, Kirsty Wienand, Sumbul J. Khan, Nazli Serin, Meng Wang, Eleonora Calabretta, Joji Shimono, Samantha Van Seters, Sam Wiseman, Saveliy Belkin, David Isaac Heiman, Robert A Redd, Margaret A. Shipp, Gad Getz
Journal: Blood
Blood blood.2024025652.
https://doi.org/10.1182/blood.2024025652
Published: 2024
Includes: Supplemental data
Journal Articles

Novel Non-Coding Candidate Drivers of Multiple Myeloma Linked to Plasma Cell Tumor Biology and B Cell Development

Jean-Baptiste Alberge, Ankit K. Dutta, Andrea Poletti, Oliver Priebe, Tim H.H. Coorens, Elizabeth D. Lightbody, Rosa Toenges, Xavi Loinaz, Sofia Wallin, Andrew Dunford, Cody J. Boehner, Erica M. Horowitz, Nang Kham Su, Hadley Barr, Laura Hevenor, Katherine Towle, Rashmika Beesam, Jenna D. Beckwith, Jacqueline Perry, David M. Cordas dos Santos, Luca Bertamini, Kirsten Kübler, Carolina Terragna, Elena Zamagni, Julian Hess, Romanos Sklavenitis-Pistofidis, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1894.
https://doi.org/10.1182/blood-2024-205523
Published: 2024
Journal Articles

A 1,000-Genome Map for Multiple Myeloma and Its Precursor Stages, and Its Impact on Clinical Outcome

Jean-Baptiste Alberge, Ankit K. Dutta, Andrea Poletti, Tim H.H. Coorens, Elizabeth D. Lightbody, Rosa Toenges, Xavi Loinaz, Sofia Wallin, Andrew Dunford, Oliver Priebe, Cody J. Boehner, Erica M. Horowitz, Nang Kham Su, Hadley Barr, Laura Hevenor, Katherine Towle, Rashmika Beesam, Jenna D. Beckwith, Jacqueline Perry, David M. Cordas dos Santos, Luca Bertamini, Patricia Greipp, Kirsten Kübler, Peter F. Arndt, Carolina Terragna, Elena Zamagni, Julian Hess, Romanos Sklavenitis-Pistofidis, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2024-203517
Published: 2024
Journal Articles

Acute GvHD of the Gut Is Associated with Minor Histocompatibility Antigens Cross-Reactive Against Gut-Tropic Viral Epitopes

Nicoletta Cieri, Yiren Shao, Kaila Power, Vincent T. Ho, Jonathan Stevens, William J. Lane, Haesook T. Kim, Donna S. Neuberg, Chip Stewart, Gad Getz, Jerome Ritz, Robert J. Soiffer, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 102.
https://doi.org/10.1182/blood-2024-198976
Published: 2024
Journal Articles

The Impact of Therapeutic Selective Pressure on the Evolutionary Landscape of Chronic Lymphocytic Leukemia

Negin Karisani, Amit Sud, Liang Li, Satyen Gohil, Kristy Schlueter-Kuck, Laura Rassenti, Tuan N. Tran, Leo Wang-Kit Cheung, Iliana Edith Szafer-Glusman, James P. Dean, Guang Chen, Junko Tsuji, Neil E. Kay, Kanti R. Rai, Jennifer R. Brown, John G. Gribben, John C. Byrd, Donna S. Neuberg, Chip Stewart, Ivana Bozic, Thomas J. Kipps, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3233.
https://doi.org/10.1182/blood-2024-199916
Published: 2024
Journal Articles

An Analytic Framework for the Prediction of Gvl Minor Histocompatibility Antigens to Prevent or Treat Post-Transplant Relapse

Nicoletta Cieri, Liang Li, Nidhi Hookeri, Kari Stromhaug, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 361.
https://doi.org/10.1182/blood-2023-187705
Published: 2023
Journal Articles

Systematic Prediction of Minor Histocompatibility Antigens to Inform GvHD Outcomes after Allogeneic Stem Cell Transplantation

Nicoletta Cieri, Nidhi Hookeri, Kari Stromhaug, Liang Li, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 652.
https://doi.org/10.1182/blood-2023-187451
Published: 2023
Journal Articles

Genome Sequencing to Discover Drivers of Clonal Expansion in Smoldering Multiple Myeloma

Jean-Baptiste Alberge, Ankit K. Dutta, Elizabeth D. Lightbody, Andrea Poletti, Sofia Wallin, Andrew Dunford, Tim Coorens, Xavi Loinaz, Cody J. Boehner, Nang Kham Su, Laura Hevenor, Katherine Towle, Jacqueline Perry, Kirsten Kübler, Romanos Sklavenitis-Pistofidis, Julian Hess, Chip Stewart, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2023) 142 (Supplement 1): 4143.
https://doi.org/10.1182/blood-2023-184900
Published: 2023
Journal Articles

Reconstructing the Genomic History of Multiple Myeloma Precursor Disease: Novel Insights and Clinical Applicability

Jean-Baptiste Alberge, Ankit K. Dutta, Elizabeth D. Lightbody, Andrea Poletti, Andrew Dunford, Oliver Priebe, Julian M. Hess, Cody J. Boehner, Romanos Sklavenitis-Pistofidis, Nang Kham Su, Erica Horowitz, Hadley Barr, Jenna B. Beckwith, Laura Hevenor, Katherine Towle, Jacqueline Perry, Esther Rheinbay, Chip Stewart, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 4257–4258.
https://doi.org/10.1182/blood-2022-167041
Published: 2022
Journal Articles

Systematic Identification of Autosomal and Y-Encoded Minor Histocompatibility Antigens Reveals Predictors of Chronic Gvhd and Candidate GVL Targets

Nicoletta Cieri, Nidhi Hookeri, Kari Stromhaug, Jonathan Stevens, Kameron Kooshesh, Susan Klaeger, Karl R. Clauser, Siranush Sarkizova, David A. Braun, Livius Penter, Giacomo Oliveira, Haesook T. Kim, William J. Lane, Shuqiang Li, Kenneth J. Livak, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Derin B. Keskin, Chip Stewart, Alexander Gusev, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 4762–4764.
https://doi.org/10.1182/blood-2022-162841
Published: 2022
Journal Articles

Monitoring Plasma Cells and Clonal Emergence through Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma

Ankit K. Dutta, Jean-Baptiste Alberge, Elizabeth D. Lightbody, Cody J. Boehner, Romanos Sklavenitis-Pistofidis, Amanda Cao, Tarek H. Mouhieddine, Anna Cowan, Nang Kham Su, Andrew Dunford, Erica Horowitz, Hadley Barr, Jenna B. Beckwith, Laura Hevenor, Jacqueline Perry, Ornkleaw Zepp, Thai Bui, Steven Gross, Omar Nadeem, Chip Stewart, Daniel Auclair, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2022) 140 (Supplement 1): 9927–9928.
https://doi.org/10.1182/blood-2022-169034
Published: 2022
Journal Articles

Evolutionary History of Transformation from Chronic Lymphocytic Leukemia to Richter Syndrome

Erin Michelle Parry, Romain Guieze, Ignaty Leshchiner, Connor Johnson, Eugen Tausch, Sameer A. Parikh, Camilla K Lemvigh, Julien Broséus, Sébastien Hergalant, Connor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Shuqiang Li, Geoffrey G Fell, Robert A. Redd, Ziao Lin, Binyamin A. Knisbacher, Christof Schneider, Stacey M. Fernandes, Julian M. Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William G. Wierda, Florence Cymbalista, Pierre Feugier, Neil E. Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S. Neuberg, Matthew S. Davids, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1530–1533.
https://doi.org/10.1182/blood-2022-160335
Published: 2022
Journal Articles

Genomic Profiling of Smoldering Multiple Myeloma Classifies Molecular Groups with Distinct Pathogenic Phenotypes and Clinical Outcomes

Shankara Anand, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Eileen M Boyle, Yu-Tzu Tai, Carl J Neuse, Selina J Chavda, Cody J. Boehner, Mahshid Rahmat, Benny Zhitomirsky, Andrew Dunford, Ankit K. Dutta, Chip Stewart, Lorenzo Trippa, Tineke Casneuf, Efstathios Kastritis, Brian A Walker, Faith E Davies, Meletios A. Dimopoulos, P. Leif Bergsagel, Kwee Yong, Gareth J. Morgan, François Aguet, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 723.
https://doi.org/10.1182/blood-2021-150767
Published: 2021
Journal Articles

Clonal Hematopoiesis Prevalence Increases throughout Treatment of Newly Diagnosed Multiple Myeloma Patients

Tarek H. Mouhieddine, Chidimma Nzerem, Robert A. Redd, Andrew Dunford, Matthew Joseph Leventhal, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Habib El-Khoury, David P. Steensma, Benjamin L. Ebert, Robert J. Soiffer, Jonathan J Keats, Shaadi Mehr, Daniel Auclair, Adam S. Sperling, Chip Stewart, Gad Getz, Irene M. Ghobrial
Journal: Blood
Blood (2021) 138 (Supplement 1): 1091.
https://doi.org/10.1182/blood-2021-152025
Published: 2021
Journal Articles

The CLL-1100 Project: Towards Complete Genomic Characterization and Improved Prognostics for CLL

Binyamin A. Knisbacher, PhD, Ziao Lin, BS, Cynthia K. Hahn, MD PhD, Ferran Nadeu, Martí Duran-Ferrer, Kristen E. Stevenson, MS, Eugen Tausch, MD, Alex Barbera-Mourelle, Andrew Dunford, Shankara Anand, Julio Delgado, MD, Julian M. Hess, Amaro Taylor-Weiner, PhD, Helene Kretzmer, PhD, Pablo Bousquets Muñoz, Conner J. Shaughnessy, Stacey M. Fernandes, BS, Mariela Sivina, Laura Z. Rassenti, PhD, Alexander Meissner, PhD, Adrian Wiestner, MD PhD, Jan A. Burger, MD PhD, Thomas J. Kipps, MD PhD, Jennifer R Brown, MD PhD, Michael Hallek, François Aguet, PhD, Donna S. Neuberg, ScD, Xose S Puente, PhD, Chip Stewart, PhD, José I. Martín-Subero, PhD, Stephan Stilgenbauer, MD, Catherine J. Wu, MD, Elías Campo, MD PhD, Gad Getz, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-140987
Published: 2020
Journal Articles

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Kirsty Wienand, Atanas Kamburov, Gabriel K. Griffin, Pei-Hsuan Chen, Ana Lako, Robert A. Redd, Claire M. Cote, Matthew D. Ducar, Aaron R. Thorner, Scott J. Rodig, Gad Getz, Margaret A. Shipp
Journal: Blood
Blood (2019) 134 (26): 2369–2382.
https://doi.org/10.1182/blood.2019002067
Published: 2019
Includes: Supplemental data
Journal Articles

Comparative Genomic Analyses Defines Shared and Unique Features of cHL and PMBL and New Mechanisms of Sensitivity to PD-1 Blockade

Kirsty Wienand, PhD, Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, David Wu, MD PhD, Jaegil Kim, PhD, Atanas Kamburov, PhD, Timothy Wood, Fathima Zumla Cader, MD PhD MRCP, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Anwesha Nag, PhD, Gabriel K Griffin, MD, Pei-Hsuan Chen, Alexander T Heubeck, BS, Michael J Buonopane, BS, Kamil Bojarczuk, PhD, Claire McEwen Cote, Lee N. Lawton, PhD, Philippe Armand, MD PhD, Scott J Rodig, MD PhD, Jonathan R. Fromm, MD PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1493.
https://doi.org/10.1182/blood-2019-131904
Published: 2019
Journal Articles

Validation of the Genetically-Defined DLBCL Subtypes and Generation of a Parsimonious Probabilistic Classifier

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Timothy Wood, Andrew Dunford, MS, Kirsty Wienand, PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 920.
https://doi.org/10.1182/blood-2019-131250
Published: 2019
Journal Articles

Comprehensive Genomic Analysis of Flow-Sorted Hodgkin Reed Sternberg Cells Reveals Additional Genetic Bases of Immune Evasion

Kirsty Wienand, PhD, Bjoern Chapuy, MDPhD, Chip Stewart, PhD, Andrew Dunford, MS, David Wu, MD PhD, Jaegil Kim, PhD, Atanas Kamburov, PhD, Fathima Zumla Cader, MD PhD MRCP, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Alexander T Heubeck, BS, Michael J Buonopane, BS, Philippe Armand, MD PhD, Scott J Rodig, MD, Jonathan R. Fromm, MD PhD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1559.
https://doi.org/10.1182/blood-2018-99-118453
Published: 2018
Journal Articles

Comprehensive Genomic Analysis of Primary Mediastinal B-Cell Lymphoma

Bjoern Chapuy, MDPhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Kirsty Wienand, PhD, Atanas Kamburov, PhD, Gabriel Kenneth Griffin, MD, Claire McEwen Cote, Matthew D. Ducar, MS, Aaron R. Thorner, PhD, Scott J Rodig, MD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1564.
https://doi.org/10.1182/blood-2018-99-118135
Published: 2018