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Journal Articles

Distinct archetypes of clonal dynamics underlie response and resistance to diverse CLL therapies

Free
Marwan Kwok, Connor Johnson, Eugen Tausch, Liang Li, Chip Stewart, Carrie Cibulskis, Sam Pollock, Johanna van Vliet, Fanny Dao, Satyen Gohil, Madison Lee, Brian Danysh, Anke Schilhabel, Sandra Robrecht, Marc Zapatka, Emanuela Ghia, Laura Rassenti, Lita Freeman, Erica Bhavsar, Andy Itsara, Othman Al-Sawaf, John Allan, Richard Furman, Dan Avi Landau, Thomas Kipps, Adrian Wiestner, Matthias Ritgen, Kirsten Fischer, Barbara Eichhorst, Michael Hallek, Stephan Stilgenbauer, Ivana Bozic, Ignaty Leshchiner, Gad Getz, Catherine Wu
Journal: Blood
Blood (2025) 146 (Supplement 1): 245.
https://doi.org/10.1182/blood-2025-245
Published: 2025
Journal Articles

Systematic molecular profiling to identify determinants of response to ibrutinib

Free
Negin Karisani, Amit Sud, Liang Li, Satyen Gohil, Kristy Schlueter-Kuck, Zhihan Zhu, Laura Rassenti, Tuan Tran, Leo Cheung, Iliana Szafer-Glusman, James Dean, Guang Chen, Junko Tsuji, Marzia Palma, Robert Månsson, Neil Kay, Kanti Rai, Jennifer Brown, John Gribben, John Byrd, Donna Neuberg, Chip Stewart, Ivana Bozic, Helene Kretzmer, Thomas Kipps, Gad Getz, Catherine Wu
Journal: Blood
Blood (2025) 146 (Supplement 1): 3881.
https://doi.org/10.1182/blood-2025-3881
Published: 2025
Journal Articles

Daratumumab monotherapy versus active monitoring in patients with high-risk smoldering multiple myeloma: Aquila outcomes based on mayo 2018/IMWG 2020 risk stratification, IMWG 2020 plus cytogenetic criteria, and age

Free
Peter Voorhees, Meletios Dimopoulos, Yaël Cohen, Fredrik Schjesvold, Vania Hungria, Irwindeep Sandhu, Jindriska Lindsay, Ross Baker, Kenshi Suzuki, Hiroshi Kosugi, Mark-David Levin, Meral Beksac, Keith Stockerl-Goldstein, Hila Magen, Albert Oriol, Gabor Mikala, Gonzalo Garate, Koen Theunissen, Ivan Špička, Anne Mylin, Simon Hallam, Sara Bringhen, Katarina Uttervall, Bartosz Pula, Abdullah Khan, Eva Medvedova, J Christine Ye, Andrew Cowan, Philippe Moreau, María-Victoria Mateos, Hartmut Goldschmidt, Diego Vieyra, Ashta Raval, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, S. Vincent Rajkumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 372.
https://doi.org/10.1182/blood-2025-372
Published: 2025
Journal Articles

Safety and efficacy of AZD0120, a BCMA/CD19 dual-targeting CAR T-cell therapy, in relapsed/refractory multiple myeloma: Preliminary Results from the DURGA-1 Phase 1b/2 study

Free
Shambavi Richard, Mahmoud Gaballa, Tara Gregory, Saurabh Chhabra, Larry Anderson, Luciano Costa, Caitlin Costello, Scott Goldsmith, Doris Hansen, Sridevi Rajeeve, Shaji Kumar, Aravind Ramakrishnan, Minoo Battiwalla, Ajay Nooka, Hira Shaikh, Meiyue Grace Hong, Steven Wang, Patricia Cheung, Liang Li, Binod Dhakal
Journal: Blood
Blood (2025) 146 (Supplement 1): 269.
https://doi.org/10.1182/blood-2025-269
Published: 2025
Journal Articles

5-HT prompt TPO mRNA transcription via H3Q5 serotonylation

Free
Liang Li, Mo Yang, En-yu Liang, ouyang cheng, Chun Chen
Journal: Blood
Blood (2025) 146 (Supplement 1): 6751.
https://doi.org/10.1182/blood-2025-6751
Published: 2025
Journal Articles

Efficacy and safety of daratumumab in intermediate/high-risk smoldering multiple myeloma: final analysis of CENTAURUS

Available to Purchase
Clinical Trials & Observations
Ola Landgren, Ajai Chari, Yael C. Cohen, Andrew Spencer, Peter M. Voorhees, Irwindeep Sandhu, Matthew W. Jenner, Dean Smith, Michele Cavo, Niels W. C. J. van de Donk, Meral Beksac, Philippe Moreau, Hartmut Goldschmidt, Diego Vieyra, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, Craig C. Hofmeister
Journal: Blood
Blood (2025) 145 (15): 1658–1669.
https://doi.org/10.1182/blood.2024025897
Published: 2025
Includes: Supplemental data
Journal Articles

The Impact of Therapeutic Selective Pressure on the Evolutionary Landscape of Chronic Lymphocytic Leukemia

Free
Negin Karisani, Amit Sud, Liang Li, Satyen Gohil, Kristy Schlueter-Kuck, Laura Rassenti, Tuan N. Tran, Leo Wang-Kit Cheung, Iliana Edith Szafer-Glusman, James P. Dean, Guang Chen, Junko Tsuji, Neil E. Kay, Kanti R. Rai, Jennifer R. Brown, John G. Gribben, John C. Byrd, Donna S. Neuberg, Chip Stewart, Ivana Bozic, Thomas J. Kipps, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3233.
https://doi.org/10.1182/blood-2024-199916
Published: 2024
Journal Articles

Phase 3 Randomized Study of Daratumumab Monotherapy Versus Active Monitoring in Patients with High-Risk Smoldering Multiple Myeloma: Primary Results of the Aquila Study

Free
Meletios-Athanasios Dimopoulos, Peter M. Voorhees, Fredrik Schjesvold, Yael C. Cohen, Vania Hungria, Irwindeep Sandhu, Jindriska Lindsay, Ross Ian Baker, Kenshi Suzuki, Hiroshi Kosugi, Mark-David Levin, Meral Beksac, Keith Stockerl-Goldstein, Albert Oriol, Gabor Mikala, Gonzalo Martin Garate, Koen Theunissen, Ivan Spicka, Anne K. Mylin, Sara Bringhen, Katarina Uttervall, Bartosz Michal Pula, Eva Medvedova, Andrew J. Cowan, Philippe Moreau, Maria-Victoria Mateos, Hartmut Goldschmidt, Tahamtan Ahmadi, Linlin Sha, Els Rousseau, Liang Li, Robyn M. Dennis, Robin Carson, Vincent Rajkumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 773.
https://doi.org/10.1182/blood-2024-201057
Published: 2024
Journal Articles

Systematic Prediction of Minor Histocompatibility Antigens to Inform GvHD Outcomes after Allogeneic Stem Cell Transplantation

Free
Nicoletta Cieri, Nidhi Hookeri, Kari Stromhaug, Liang Li, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 652.
https://doi.org/10.1182/blood-2023-187451
Published: 2023
Journal Articles

Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors

Free
Aishath Naeem, Liang Li, Filippo Utro, Justin Cha, Junko Tsuji, Stacey M Fernandes, Roberta Santos Azevedo, Francesca Morelli, Zunqiu Wang, Samantha J. Shupe, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P Danysh, Alexandria Kluge, Matthew S Davids, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown
Journal: Blood
Blood (2023) 142 (Supplement 1): 4623.
https://doi.org/10.1182/blood-2023-186052
Published: 2023
Journal Articles

An Analytic Framework for the Prediction of Gvl Minor Histocompatibility Antigens to Prevent or Treat Post-Transplant Relapse

Free
Nicoletta Cieri, Liang Li, Nidhi Hookeri, Kari Stromhaug, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 361.
https://doi.org/10.1182/blood-2023-187705
Published: 2023
Journal Articles

Development of a Same-Day Closed CAR-T Cell Manufacturing Process to Generate Lentivector Loaded Lymphocytes Ready for Subcutaneous Injection

Free
Sid Kerkar, Lintao Liu, Michael Betts, Liang Li, Michelle Andraza, Ewa Jaruga-Killeen, Cody Gowan, Ting Han, Jia Shi, Rang Gao, Suraj Kachgal, Gregory Wade, Wei Zhang, Gregory Frost
Journal: Blood
Blood (2023) 142 (Supplement 1): 6812.
https://doi.org/10.1182/blood-2023-189117
Published: 2023
Journal Articles

Efficacy and Safety of Daratumumab (DARA) Monotherapy in Patients with Intermediate-Risk or High-Risk Smoldering Multiple Myeloma (SMM): Final Analysis of the Phase 2 Centaurus Study

Free
Ola Landgren, Ajai Chari, Yael C. Cohen, Andrew Spencer, Peter M. Voorhees, Irwindeep Sandhu, Matthew W. Jenner, Dean Smith, Michele Cavo, Niels WCJ van de Donk, Meral Beksac, Philippe Moreau, Hartmut Goldschmidt, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, Craig C. Hofmeister
Journal: Blood
Blood (2023) 142 (Supplement 1): 210.
https://doi.org/10.1182/blood-2023-181765
Published: 2023
Journal Articles

Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples

Free
Jasneet Kaur Khalsa, Justin Cha, Filippo Utro, Aishath Naeem, Ishwarya Murali, Yanan Kuang, Kevin Vasquez, Liang Li, Svitlana Tyekucheva, Stacey M. Fernandes, Lauren Veronese, Romain Guieze, Binu Kandathilparambil Sasi, Zixu Wang, John-Hanson Machado, Harrison Bai, Maryam Alasfour, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P. Danysh, Kara Slowik, Raquel A. Jacobs, Matthew S. Davids, Cloud P. Paweletz, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown
Journal: Blood
Blood (2023) 142 (5): 421–433.
https://doi.org/10.1182/blood.2022016600
Published: 2023
Includes: Supplemental data
Journal Articles

Evolutionary History of Transformation from Chronic Lymphocytic Leukemia to Richter Syndrome

Free
Erin Michelle Parry, Romain Guieze, Ignaty Leshchiner, Connor Johnson, Eugen Tausch, Sameer A. Parikh, Camilla K Lemvigh, Julien Broséus, Sébastien Hergalant, Connor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Shuqiang Li, Geoffrey G Fell, Robert A. Redd, Ziao Lin, Binyamin A. Knisbacher, Christof Schneider, Stacey M. Fernandes, Julian M. Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William G. Wierda, Florence Cymbalista, Pierre Feugier, Neil E. Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S. Neuberg, Matthew S. Davids, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1530–1533.
https://doi.org/10.1182/blood-2022-160335
Published: 2022
Journal Articles

PDGF-BB and Its Role in Megakaryopoiesis and Thrombocythemia

Free
Mo Yang, Liang Li, Yi Luo, Weiqing Su, Huimin Kong, Beng H Chong, Jieyu Ye
Journal: Blood
Blood (2021) 138 (Supplement 1): 4217.
https://doi.org/10.1182/blood-2021-151850
Published: 2021
Journal Articles

Tanshinone Iia Inhibits Megakaryopoiesis in Immune Vasculitis

Free
Hui Chen, Min Zhou, Huiying Shu, Weiqing Su, Liuming Yang, Liang Li, Beng H Chong, Mo Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 4288.
https://doi.org/10.1182/blood-2021-152162
Published: 2021
Journal Articles

Effect of Thrombospondin-1 on Apoptosis of Human Megakaryocytic Leukemia Cells

Free
Huimin Kong, Qianli Jiang, Weiqing Su, Yi Luo, Hui Ge, Liang Li, Beng H Chong, Mo Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 4351.
https://doi.org/10.1182/blood-2021-149054
Published: 2021
Journal Articles

Anti-Apoptotic Effect of Angelica Polysaccharide (APS) on Cryopreservation of Platelets

Free
Mo Yang, Weiqing Su, Liuming Yang, Huimin Kong, Huiling Wei, Honghua Sun, Beng H Chong, Liang Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 3250.
https://doi.org/10.1182/blood-2021-151963
Published: 2021
Journal Articles

Thrombopoietin Protects Neural Cells and Endothelial Cells from Apoptosis Via PI3K/AKT Pathway

Free
Liang Li, PhD, Junyan Wang, Jieyu Ye, PhD, Liuming Yang, Beng H Chong, MBBS, PhD, Mo Yang
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-140262
Published: 2020