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Neil E. Kay
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Journal Articles

Rewiring Cancer Drivers to Induce Apoptosis By Transcriptional Chemical Inducers of Proximity in Chronic Lymphocytic Leukemia

Weiguo Han, Aisharya Bhattacharya, Wenzhi Ji, Basel A. Karim, Roman C. Sarott, Meredith Nix, Sai Gourisankar, Andrey Krokhotin, Sutapa Sinha, Zhiquan Wang, Tait D. Shanafelt, Sameer A. Parikh, Nathanael S. Gray, Gerald R. Crabtree, Neil E. Kay
Journal: Blood
Blood (2024) 144 (Supplement 1): 4606.
https://doi.org/10.1182/blood-2024-203582
Published: 2024
Journal Articles

Incidence and Prevalence of Chronic Lymphocytic Leukemia in the 7-County Region Around Mayo Clinic, Rochester, Minnesota

Bryan A. Vallejo, Sara Achenbach, Kari G. Rabe, Aaron D. Norman, Celine M. Vachon, James R. Cerhan, Esteban Braggio, Susan M. Schwager, Tait D. Shanafelt, Curtis A. Hanson, Sameer A. Parikh, Neil E. Kay, Timothy G. Call, Susan L. Slager
Journal: Blood
Blood (2024) 144 (Supplement 1): 6801.
https://doi.org/10.1182/blood-2024-209069
Published: 2024
Journal Articles

Serum Immunoglobulins Are an Independent Prognostic Marker of Time to First Therapy in Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) and Monoclonal B-Cell Lymphocytosis (MBL)

Yuan Yao, Kari G. Rabe, Cristine Allmer, Geffen Kleinstern, Nicholas J. Boddicker, Shulan Tian, Laura A. Bruins, Daniel R. O'Brien, Aaron D. Norman, Huihuang Yan, Timothy G. Call, Paul J. Hampel, Yucai Wang, Eli Muchtar, Saad S. Kenderian, Neil E. Kay, Celine M. Vachon, James R. Cerhan, Susan L. Slager, Esteban Braggio, Sameer A. Parikh
Journal: Blood
Blood (2024) 144 (Supplement 1): 4616.
https://doi.org/10.1182/blood-2024-194925
Published: 2024
Journal Articles

Treatment with First-Line Ibrutinib Improves Overall Survival in Patients with Chronic Lymphocytic Leukemia (CLL) and High-Risk Genomic Features to Rates Approximating an Age-Matched US Population: Pooled Analysis of Phase 3 Trials with 10 Years of Follow-up

Jan A. Burger, Neil E. Kay, John N. Allan, Paul M Barr, Jacqueline C. Barrientos, Carolyn Owen, Victoria Wang, Hsin-Hui Huang, Lynne Neumayr, Christopher Abbazio, Gabriel S. Krigsfeld, Sneh Mody, Paolo Ghia, Tait D. Shanafelt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4615.
https://doi.org/10.1182/blood-2024-194382
Published: 2024
Journal Articles

Prevalence, Genetic Predispositions and Clinical Consequences of Non-CLL-Type MBL: Screening in 10,330 Individuals

Yuan Yao, Sameer A. Parikh, Sara Achenbach, Aaron D. Norman, Kari G. Rabe, Nicholas J. Boddicker, Janet E. Olson, Rosalie Griffin, Soren Basnet, Dennis P. Robinson, Mingma Hoel, Alyssa I Clay-Gilmour, Stacey Lehman, Timothy G. Call, James R. Cerhan, Celine M. Vachon, Neil E. Kay, Esteban Braggio, Curtis A. Hanson, Tait D. Shanafelt, Susan L. Slager
Journal: Blood
Blood (2024) 144 (Supplement 1): 397.
https://doi.org/10.1182/blood-2024-194932
Published: 2024
Journal Articles

Outcomes with Venetoclax-Based Treatment in Patients with Covalent Bruton Tyrosine Kinase Inhibitor (cBTKi)-Treated, Chemotherapy-Naïve Chronic Lymphocytic Leukemia (CLL): An International Retrospective Study

Paul J. Hampel, Kari G. Rabe, Romain Guieze, Yucai Wang, Emmanuelle Ferrant, Saad S. Kenderian, Marie Sarah Dilhuydy, Eli Muchtar, Anne-Sophie Michallet, Jose F. Leis, Luca Inchiappa, Mazie Tsang, Aline Clavert, Talal Hilal, Stephane Lepretre, Ricardo D. Parrondo, Emmanuelle Tchernonog, Amber Koehler, Lin Wang, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Luc-Matthieu Fornecker, Sameer A. Parikh, Loic Ysebaert
Journal: Blood
Blood (2024) 144 (Supplement 1): 1856.
https://doi.org/10.1182/blood-2024-198200
Published: 2024
Journal Articles

Combination Interaction Effects of Ibrutinib with Variety Drugs in in Vitro Mesenchymal Stromal Cell System in Chronic Lymphocytic Leukemia

Weiguo Han, Connie Lesnick, Aisharya Bhattacharya, Sutapa Sinha, Zhiquan Wang, Sameer A. Parikh, Neil E. Kay
Journal: Blood
Blood (2024) 144 (Supplement 1): 6760.
https://doi.org/10.1182/blood-2024-203943
Published: 2024
Journal Articles

The Impact of Therapeutic Selective Pressure on the Evolutionary Landscape of Chronic Lymphocytic Leukemia

Negin Karisani, Amit Sud, Liang Li, Satyen Gohil, Kristy Schlueter-Kuck, Laura Rassenti, Tuan N. Tran, Leo Wang-Kit Cheung, Iliana Edith Szafer-Glusman, James P. Dean, Guang Chen, Junko Tsuji, Neil E. Kay, Kanti R. Rai, Jennifer R. Brown, John G. Gribben, John C. Byrd, Donna S. Neuberg, Chip Stewart, Ivana Bozic, Thomas J. Kipps, Gad Getz, Catherine J. Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3233.
https://doi.org/10.1182/blood-2024-199916
Published: 2024
Journal Articles

Prediction of outcomes for high-count monoclonal B lymphocytosis using an epigenetic and immunogenetic signature

Brief Report
Salma B. Abdelbaky, Brian Giacopelli, Kari G. Rabe, Kyoko Yamaguchi, Yue-Zhong Wu, Huihuang Yan, Tait D. Shanafelt, Sameer A. Parikh, Wei Ding, Paul J. Hampel, Sochilt Brown, James R. Cerhan, Celine M. Vachon, Neil E. Kay, Curtis A. Hanson, Alexander S. Parker, Esteban Braggio, Susan L. Slager, Christopher C. Oakes
Journal: Blood
Blood (2024) 143 (17): 1752–1757.
https://doi.org/10.1182/blood.2023022180
Published: 2024
Includes: Supplemental data
Journal Articles

CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS

R. Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Elizabeth L. Siegler, James H. Girsch, Olivia L. Sirpilla, Carli M. Stewart, Kun Yun, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Evandro D. Bezerra, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Brooke L. Kimball, Long K. Mai, Truc N. Huynh, Wendy K. Nevala, Kristina Ilieva, Christian Augsberger, Maria Patra-Kneuer, Jürgen Schanzer, Jan Endell, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Saad S. Kenderian
Journal: Blood
Blood (2024) 143 (3): 258–271.
https://doi.org/10.1182/blood.2022018905
Published: 2024
Includes: Supplemental data
Journal Articles

Ibrutinib-based therapy reinvigorates CD8 + T cells compared to chemoimmunotherapy: immune monitoring from the E1912 trial

Clinical Trials & Observations Brief Report
Despoina Papazoglou, Xin Victoria Wang, Tait D. Shanafelt, Connie E. Lesnick, Nikolaos Ioannou, Giulia De Rossi, Sylvia Herter, Marina Bacac, Christian Klein, Martin S. Tallman, Neil E. Kay, Alan G. Ramsay
Journal: Blood
Blood (2024) 143 (1): 57–63.
https://doi.org/10.1182/blood.2023020554
Published: 2024
Includes: Supplemental data
Journal Articles

Chronic Lymphoproliferative Disorder of Natural Killer Cells: Patient Characteristics, Laboratory Features, and Clinical Outcomes

Richard C. Godby, Kari G. Rabe, Steven R. Hwang, Hadiyah Audil, Susan L. Slager, Saad S. Kenderian, Neil E. Kay, Yucai Wang, Paul J Hampel, Sameer A. Parikh, Wei Ding, Min Shi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4446.
https://doi.org/10.1182/blood-2023-182545
Published: 2023
Journal Articles

Targeting Covalent and Non-Covalent Btki-Resistant CLL Using the Dual Irreversible/Reversible 4 th Generation BTK Inhibitor LP-168

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Samon Benrashid, Andrew Mitchell, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Shanmugapriya Thangavadivel, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Kerry A Rogers, Adam S Kittai, Seema A Bhat, John C. Byrd, Deepa Sampath, Rosa Lapalombella, Weiguo Han, Neil E. Kay, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 416.
https://doi.org/10.1182/blood-2023-178259
Published: 2023
Journal Articles

Mosaic Chromosomal Alterations and Monoclonal B-Cell Lymphocytosis: Relationship and Risk of Hematologic Malignancies

Rosalie Griffin, Aswin Sekar, Sameer A. Parikh, Giulio Genovese, Dennis P. Robinson, Aaron D. Norman, Janet E. Olson, Kari G. Rabe, Nicholas J. Boddicker, Paul J. Hampel, Neil E. Kay, Timothy G. Call, James R. Cerhan, Esteban Braggio, Curtis A. Hanson, Caline M. Vachon, Tait D. Shanafelt, Benjamin L. Ebert, Susan L. Slager
Journal: Blood
Blood (2023) 142 (Supplement 1): 2690.
https://doi.org/10.1182/blood-2023-184696
Published: 2023
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients into Novel Categories with Different Risk of Early Treatment

Federico Pozzo, Francesca Cuturello, Edith Villegas Garcia, Francesca Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni Francesco D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Francesco Di Raimondo, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Alessio Ansuini, Chris Fegan, Chris Pepper, Andrea Pepper, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 1892.
https://doi.org/10.1182/blood-2023-177884
Published: 2023
Journal Articles

High Deletion Burden Identified By Whole Genome Sequencing Is Associated with Enhanced Risk in del17p CLL Patients

Preeti Trisal, Esteban Braggio, Nicholas Stong, Kay L. Medina, Sameer A. Parikh, Daniel L. Van Dyke, Kari G. Rabe, Zhiquan Wang, C. Chris Huang, Anita K. Gandhi, Neil E. Kay
Journal: Blood
Blood (2023) 142 (Supplement 1): 6509.
https://doi.org/10.1182/blood-2023-173881
Published: 2023
Journal Articles

Incidence of Richter Transformation in Patients with Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL): A Cohort Study Evaluating Different Therapeutic Eras

Paul J. Hampel, Kari G. Rabe, Yucai Wang, Steven R Hwang, Saad S. Kenderian, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Wei Ding, Sameer A. Parikh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3271.
https://doi.org/10.1182/blood-2023-185076
Published: 2023
Journal Articles

Clinical Outcomes with Venetoclax-Based Treatment Regimens in Patients with Chronic Lymphocytic Leukemia (CLL)

Paul J. Hampel, Kari G. Rabe, Yucai Wang, Saad S. Kenderian, Wei Ding, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Sameer A. Parikh
Journal: Blood
Blood (2023) 142 (Supplement 1): 3276.
https://doi.org/10.1182/blood-2023-183007
Published: 2023
Journal Articles

Aberrant Heterochromatin Silences Immune Response Genes in Chronic Lymphocytic Leukemia

Zhiquan Wang, Olivia M. Depies, Sutapa Sinha, Weiguo Han, Sameer A. Parikh, Neil E. Kay
Journal: Blood
Blood (2023) 142 (Supplement 1): 3258.
https://doi.org/10.1182/blood-2023-182898
Published: 2023
Journal Articles

Outcomes of Patients with Small Lymphocytic Lymphoma (SLL) Receiving First Line Treatment

Samuel Kosydar, Kari G. Rabe, Yucai Wang, Saad S. Kenderian, Wei Ding, Eli Muchtar, Jose F. Leis, Amber Koehler, Mazie Tsang, Ricardo Parrondo, Talal Hilal, Rachel Bubik, Susan Marie Schwager, Curtis A. Hanson, Esteban Braggio, Susan L. Slager, Min Shi, Daniel L. Van Dyke, Timothy G. Call, Neil E. Kay, Sameer A. Parikh, Paul J Hampel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3284.
https://doi.org/10.1182/blood-2023-181866
Published: 2023