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Journal Articles

TP53 , CD36 Mutations and CDKN2A Loss Predict Poor Outcome in Mantle Cell Lymphoma: Molecular Analysis of the FIL V-Rbac Phase 2 Trial

Riccardo Moia, Maria Elena Carazzolo, Chiara Cosentino, Mohammad Almasri, Donatella Talotta, Valentina Tabanelli, Giovanna Motta, Federica Melle, Maria Vittoria Sacchi, Andrea Evangelista, Luca Cividini, Maria Chiara Tisi, Merli Anna, Stefano Fiori, Alessandro Re, Claudia Castellino, Vittorio Ruggero Zilioli, Francesco Piazza, Paolo Corradini, Stefan Hohaus, Gerardo Musuraca, Francesca Gaia Rossi, Benedetta Puccini, Federica Cavallo, Filippo Ballerini, Roberta Sciarra, Alice Di Rocco, Annalisa Arcari, Carola Boccomini, Francesco Merli, Guido Gini, Monica Tani, Riccardo Bruna, Vincenzo Pavone, Marco Ladetto, Sara Galimberti, Riccardo Bomben, Valter Gattei, Ilaria Del Giudice, Simone Ferrero, Stefano Pileri, Monica Balzarotti, Gianluca Gaidano, Carlo Visco
Journal: Blood
Blood (2024) 144 (Supplement 1): 1577.
https://doi.org/10.1182/blood-2024-198076
Published: 2024
Journal Articles

Impact of Minimal Residual Disease Analysis in the Era of Rituximab Maintenance in Follicular Lymphoma: Data from “FOLL12” Phase III Trial of the Fondazione Italiana Linfomi

Simone Ferrero, Ilaria Del Giudice, Sara Galimberti, Valter Gattei, Luigi Marcheselli, Elisa Genuardi, Daniela Drandi, Mariapia Pironti, Irene Dogliotti, Aurora Maria Civita, Irene Della Starza, Giovanni Manfredi Assanto, Francesca Guerrini, Clara Bono, Riccardo Bomben, Carola Boccomini, Lucia Farina, Jacopo Olivieri, Luca Arcaini, Federica Cavallo, Filippo Ballerini, Gloria Margiotta Casaluci, Vittorio Ruggero Zilioli, Manuela Zanni, Gerardo Musuraca, Anna Merli, Benedetta Bianchi, Silvia Bolis, Vincenzo Pavone, Annalisa Chiarenza, Annalisa Arcari, Catello Califano, Samantha Pozzi, Massimo Massaia, Annarita Conconi, Tommasina Perrone, Donato Mannina, Alessandro Re, Maria Elena Nizzoli, Dimitri Dardanis, Stefano Luminari, Marco Ladetto
Journal: Blood
Blood (2024) 144 (Supplement 1): 339.
https://doi.org/10.1182/blood-2024-194832
Published: 2024
Journal Articles

High IGHV Intraclonal Diversification Identifies CLL with Good Prognosis, Features of Anergy and Specific T-Cell Profiles

Filippo Vit, Tamara Bittolo, Antonella Zucchetto, Robel Papotti, Erika Tissino, Federico Pozzo, Andrea Stacchetti, Francesca Rossi, Massimo Degan, Eva Zaina, Ilaria Cattarossi, Paola Varaschin, Paola Nanni, Michele Berton, Alessandra Braida, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Azzurra Anna Romeo, Annalisa Biagi, Giovanni D'Arena, Enrica Antonia Martino, Pietro Bulian, Massimo Gentile, Massimiliano Postorino, Laura Ballotta, Francesco Zaja, Francesco Di Raimondo, Maria Ilaria Del Principe, Valter Gattei, Riccardo Bomben
Journal: Blood
Blood (2024) 144 (Supplement 1): 75.
https://doi.org/10.1182/blood-2024-203003
Published: 2024
Journal Articles

B Cell Receptor Silencing Reveals Origin and Impacts Treatment of High-Grade B Cell Lymphomas with MYC and BCL2 Rearrangements

Stefano Casola, Paola Sindaco, Silvia Lonardi, Gabriele Varano, Ilaria Pietrini, Gaia Morello, Piera Balzarini, Hadas Neuman, Filippo Vit, Giorgio Bertolazzi, Hiroshi Arima, Marco Chiarini, Luisa Lorenzi, Vilma Pellegrini, Sabrina Giampaolo, Daniel Garzon, Cecilia Ranise, Mattia Bugatti, Chiara Pagani, Rosa Daffini, Federica Mainoldi, Viveka Selvarasa, Anojan Sivacegaram, Henry Yang, Li Ying, Valeria Cancila, Raoul Bonnal, Euplio Visco, Cristina Lopez Gonzalez, Pasquale Capaccio, Andrés José María Ferreri, Alessandra Tucci, Antonello Cabras, Giancarlo Pruneri, Arianna Di Napoli, Reiner Siebert, Riccardo Bomben, Brunangelo Falini, Marco Pizzi, Joo Y. Song, Wing Chung Chan, Maurilio Ponzoni, Ramit Mehr, Claudio Tripodo, Fabio Facchetti
Journal: Blood
Blood (2024) 144 (Supplement 1): 453.
https://doi.org/10.1182/blood-2024-203258
Published: 2024
Journal Articles

Dissecting Diffuse Large B Cell Lymphoma Heterogeneity: New Insights from a State-Specific Molecular Characterization

Robel Papotti, Filippo Vit, Federico Pozzo, Tamara Bittolo, Stefania Bettelli, Samantha Pozzi, Luca Braglia, Elisa Forti, Arianna Di Napoli, M. Christina Cox, Tamar Tadmor, Giovanna Mansueto, Pellegrino Musto, Leonardo Flenghi, Martina Quintini, Sara Galimberti, Valentina Donati, Michele Spina, Alberto Zamò, Andreas Rosenwald, Riccardo Bomben, Stefano Sacchi, Valter Gattei
Journal: Blood
Blood (2024) 144 (Supplement 1): 2975.
https://doi.org/10.1182/blood-2024-204797
Published: 2024
Journal Articles

Minimal Residual Disease Evaluation in the Context of V-Rbac, a Risk-Tailored Phase II Trial of the Fondazione Italiana Linfomi (FIL)

Riccardo Bomben, Daniela Drandi, Irene Della Starza, Clara Bono, Andrea Evangelista, Omar Perbellini, Tamara Bittolo, Elisa Genuardi, Massimo Degan, Simone Ragaini, Maria Chiara Tisi, Anna Merli, Francesca Quaglia, Alessandro Re, Claudia Castellino, Vittorio Ruggero Zilioli, Francesco Piazza, Paolo Corradini, Stefan Hohaus, Gerardo Musuraca, Francesca Gaia Rossi, Benedetta Puccini, Federica Cavallo, Filippo Ballerini, Luca Arcaini, Valter Gattei, Ilaria Del Giudice, Sara Galimberti, Carlo Visco, Simone Ferrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 4362.
https://doi.org/10.1182/blood-2024-203004
Published: 2024
Journal Articles

CD49d Expression Is Included in a Revised 4-Factor Model Predicting Outcome in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib: A Multi-Center Real-World Experience

Riccardo Bomben, Antonella Zucchetto, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Erika Tissino, Francesca Rossi, Filippo Vit, Tamara Bittolo, Robel Papotti, Federico Pozzo, Annalisa Gaglio, Massimo Degan, Jerry Polesel, Roberto Marasca, Gianluigi Reda, Andrea Visentin, Riccardo Moia, Idanna Innocenti, Candida Vitale, Roberta Murru, Marzia Varettoni, Agostino Tafuri, Francesco Zaja, Massimiliano Postorino, Enrica Antonia Martino, Adalgisa Condolucci, Davide Rossi, Antonio Cuneo, Francesco Di Raimondo, Paolo Sportoletti, Ilaria Del Giudice, Robin Foa, Francesca Romana Mauro, Marta Coscia, Luca Laurenti, Gianluca Gaidano, Livio Trentin, Maria Ilaria Del Principe, Massimo Gentile, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 3281.
https://doi.org/10.1182/blood-2023-174897
Published: 2023
Journal Articles

CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model

Laura Polcik, Danielle-Justine Danner, Riccardo Bomben, Tamara Bittolo, Lixia Li, Driti Ashok, Sandra Kissel, Natalie Koehler, Andrea Härzschel, Geoffroy Andrieux, Melanie Boerries, Sophia Engel, Theresa Haslauer, Jan Hoepner, Nadja Zaborsky, Richard Greil, Cornelius Miething, Khalid Shoumariyeh, Jesus Duque Afonso, Justus Duyster, Antonella Zucchetto, Valter Gattei, Tanja Nicole Hartmann
Journal: Blood
Blood (2023) 142 (Supplement 1): 81.
https://doi.org/10.1182/blood-2023-179726
Published: 2023
Journal Articles

Reappearance of CXCR4 dim /CD5 bright Proliferative Fraction Associates with BTK Mutations and Anticipates Progression in Ibrutinib-Treated CLL

Federico Pozzo, Gabriela Forestieri, Filippo Vit, Erika Tissino, Tamara Bittolo, Robel Papotti, Annalisa Gaglio, Lodovico Terzi Di Bergamo, Agostino Steffan, Roberta Laureana, Agostino Tafuri, Annalisa Chiarenza, Francesco Di Raimondo, Jacopo Olivieri, Francesco Zaja, Luca Laurenti, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Davide Rossi, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 4627.
https://doi.org/10.1182/blood-2023-174906
Published: 2023
Journal Articles

MRD Monitoring By Euroclonality IGH Based NGS Approach Predicts Outcome in Follicular Lymphoma Patients Lacking a Conventional BCL2::IGH Marker: A Substudy from the Fondazione Italiana Linfomi (FIL) FOLL12 Trial

Elisa Genuardi, Beatrice Alessandria, Irene Della Starza, Francesca Guerrini, Riccardo Bomben, Daniela Drandi, Martina Ferrante, Clara Bono, Roberta Soscia, Tamara Bittolo, Simone Ragaini, Salvatrice Mancuso, Emanuele Cencini, Nicola Di Renzo, Clara Mannarella, Marco Murineddu, Vittorio Stefoni, Riccardo Centurioni, Luca Baldini, Aurora Maria Civita, Valter Gattei, Sara Galimberti, Ilaria Del Giudice, Benedetto Bruno, Massimo Federico, Marco Ladetto, Christiane Pott, Stefano Luminari, Simone Ferrero
Journal: Blood
Blood (2023) 142 (Supplement 1): 4373.
https://doi.org/10.1182/blood-2023-181813
Published: 2023
Journal Articles

Early-Stage Follicular Lymphoma: Learnings from the Final Analysis of the Multicenter Phase II FIL (Fondazione Italiana Linfomi) “Miro” Trial, Combining Local Radiotherapy and MRD-Driven Immunotherapy

Alessandro Pulsoni, Maria Elena Tosti, Simone Ferrero, Stefano Luminari, Alessandra Dondi, Anna Marina Liberati, Natalia Cenfra, Daniela Renzi, Manuela Zanni, Carola Boccomini, Andrés José María Ferreri, Sara Rattotti, Vittorio Ruggero Zilioli, Patrizia Bernuzzi, Silvia Bolis, Gerardo Musuraca, Luca Nassi, Tommasina Perrone, Caterina Stelitano, Antonella Anastasia, Paolo Corradini, Giovanni Partesotti, Francesca Re, Emanuele Cencini, Clara Mannarella, Donato Mannina, Anna Lia Molinari, Monica Tani, Giorgia Annechini, Giovanni Manfredi Assanto, Lavinia Grapulin, Anna Guarini, Marzia Cavalli, Lucia Anna De Novi, Riccardo Bomben, Elena Ciabatti, Barbara Mantoan, Daniela Drandi, Irene Della Starza, Luca Arcaini, Umberto Ricardi, Valter Gattei, Sara Galimberti, Marco Ladetto, Robin Foà, Ilaria Del Giudice
Journal: Blood
Blood (2023) 142 (Supplement 1): 4399.
https://doi.org/10.1182/blood-2023-182946
Published: 2023
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients into Novel Categories with Different Risk of Early Treatment

Federico Pozzo, Francesca Cuturello, Edith Villegas Garcia, Francesca Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni Francesco D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Francesco Di Raimondo, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Alessio Ansuini, Chris Fegan, Chris Pepper, Andrea Pepper, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2023) 142 (Supplement 1): 1892.
https://doi.org/10.1182/blood-2023-177884
Published: 2023
Journal Articles

An Unsupervised Machine Learning Method Stratifies Chronic Lymphocytic Leukemia Patients in Novel Categories with Different Risk of Early Treatment

Francesca Cuturello, Federico Pozzo, Edith Natalia Villegas Garcia, Francesca Maria Rossi, Massimo Degan, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Paola Varaschin, Alessandra Braida, Michele Berton, Laura Zannier, Filippo Vit, Erika Tissino, Tamara Bittolo, Roberta Laureana, Giovanni D'Arena, Luca Laurenti, Agostino Tafuri, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Stefano Cozzini, Alessio Ansuini, Alberto Cazzaniga, Valter Gattei
Journal: Blood
Blood (2022) 140 (Supplement 1): 4111–4112.
https://doi.org/10.1182/blood-2022-159981
Published: 2022
Journal Articles

Clonal Evolution of Chronic Lymphocytic Leukemia with Bimodal CD49d Expression Reveals CD49d Plasticity

Erika Tissino, Nicola Calonaci, Federico Pozzo, Gabriela Forestieri, Lodovico Terzi Di Bergamo, Filippo Vit, Annalisa Gaglio, Riccardo Bergamin, Salvatore Milite, Stefano Cozzini, Maria Ilaria Del Principe, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Francesco Zaja, Cristoforo Fabbris, Valentina Lupato, Riccardo Bomben, Davide Rossi, Valter Gattei, Antonella Zucchetto, Giulio Caravagna
Journal: Blood
Blood (2022) 140 (Supplement 1): 9844–9846.
https://doi.org/10.1182/blood-2022-158904
Published: 2022
Journal Articles

The CXCR4 dim /CD5 bright Proliferative Fraction Reappears in Relapsed CLL Under Ibrutinib, Enriched in BTK Mutations

Federico Pozzo, Gabriela Forestieri, Giulia Ianna, Filippo Vit, Erika Tissino, Tamara Bittolo, Lodovico Terzi Di Bergamo, Roberta Laureana, Agostino Tafuri, Annalisa Chiarenza, Francesco Di Raimondo, Jacopo Olivieri, Francesco Zaja, Luca Laurenti, Maria Ilaria Del Principe, Riccardo Bomben, Antonella Zucchetto, Davide Rossi, Valter Gattei
Journal: Blood
Blood (2022) 140 (Supplement 1): 4103–4104.
https://doi.org/10.1182/blood-2022-159947
Published: 2022
Journal Articles

A Comprehensive and Systematic Analysis of Minimal Residual Disease (MRD) Monitoring in Follicular Lymphoma: Results from the Fondazione Italiana Linfomi (FIL) FOLL12 Trial

Marco Ladetto, Simone Ferrero, Ilaria Del Giudice, Sara Galimberti, Valter Gattei, Luigi Marcheselli, Barbara Mantoan, Elisa Genuardi, Beatrice Alessandria, Martina Ferrante, Irene Dogliotti, Irene Della Starza, Lucia Anna De Novi, Marzia Cavalli, Susanna Grassi, Elena Ciabatti, Francesca Guerrini, Riccardo Bomben, Massimo Degan, Eva Zaina, Tommasina Perrone, Mario Petrini, Francesca Re, Attilio Olivieri, Sara Veronica Usai, Donato Mannina, Brunangelo Falini, Delia Rota Scalabrini, Pietro Maria Stefani, Filippo Ballerini, Massimo Federico, Stefano Luminari
Journal: Blood
Blood (2021) 138 (Supplement 1): 41.
https://doi.org/10.1182/blood-2021-146773
Published: 2021
Journal Articles

Efficacy of Front-Line Ibrutinib Versus Fludarabine, Cyclophosphamide and Rituximab (FCR) in Patients with CLL. a Multicenter "Real-World" Study

Yair Herishanu, Shai Levi, Neta Goldschmidt, Fortunato Morabito, Osnat Bairey, Giovanni Del Poeta, Tomer Ziv Baran, Riva Fineman, Francesca Romana Mauro, Odit Gutwein, Gianluigi Reda, Rosa Ruchlemer, Paolo Sportoletti, Luca Laurenti, Lev Shvidel, Marta Coscia, Tamar Tadmor, Marzia Varettoni, Ariel Aviv, Roberta Murru, Andrei Breaster, Yotam Bronstein, Annalisa Chiarenza, Andrea Visentin, Daniela Pietrasanta, Giacomo Loseto, Antonella Zucchetto, Riccardo Bomben, Jacopo Olivieri, Antonino Neri, Davide Rossi, Gianluca Gaidano, Livio Trentin, Robin Foa, Antonio Cuneo, Valter Gattei, Massimo Gentile
Journal: Blood
Blood (2021) 138 (Supplement 1): 2641.
https://doi.org/10.1182/blood-2021-146848
Published: 2021
Journal Articles

Chronic Lymphocytic Leukemia Cells with Mutated Nfkbie Are Positively Selected By Microenvironmental Signals and Display Reduced Sensitivity to Ibrutinib Treatment

Alice Bonato, Riccardo Bomben, Supriya Chakraborty, Giulia Felician, Claudio Martines, Antonella Zucchetto, Annalisa Chiarenza, Giovanni Del Poeta, Roberto Marasca, Agostino Tafuri, Luca Laurenti, Aleksandar J. Dimovski, Valter Gattei, Dimitar G Efremov
Journal: Blood
Blood (2021) 138 (Supplement 1): 248.
https://doi.org/10.1182/blood-2021-149442
Published: 2021
Journal Articles

Telomere Length and CD49d Cooperate with IGHV Gene Status As Predictors of Long-Term Progression-Free Survival in CLL Patients Treated with FCR-Based Regimens

Andrea GS Pepper, PhD, Antonella Zucchetto, PhD, Kevin Norris, PhD, Erika Tissino, PhD, Jerry Polesel, Zarni Soe, David Allsup, Anna Hockaday, Pei Loo Ow, Peter Hillmen, MBChB, PhD, Andrew Rawstron, PhD, Daniel Catovsky, MD FRCP, Riccardo Bomben, PhD, Duncan M Baird, PhD, Christopher Fegan, Valter Gattei, MD, Chris Pepper, BSc, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-141279
Published: 2020
Journal Articles

Mutations of the Exportin 1 (XPO1) Gene Predict Shorter Time to First Treatment in 1092 Early Stage Chronic Lymphocytic Leukemia Patients. Α Training/Validation Study

Riccardo Moia, MD, Chiara Favini, PhD, Valentina Ferri, PhD, Riccardo Bomben, PhD, Sruthi Sagiraju, MSc, Tamara Bittolo, PhD, Lydia Scarfo, Silvia Bonfiglio, Rossana Maffei, Stefano Baldoni, Sara Raponi, PhD, Valeria Spina, PhD, Alessio Bruscaggin, PhD, Lodovico Terzi di Bergamo, Lorenzo De Paoli, Gloria Margiotta Casaluci, Clara Deambrogi, PhD, Silvia Rasi, Adalgisa Condoluci, MD, Ahad Ahmed Kodipad, Msc, Ramesh Adhinaveni, Msc, Katia Mokabari, Abdurraouf Mokhtar Mahmoud, MSc, Andrea Patriarca, MD, Jacopo Olivieri, Giovanni D'Arena, MD, Francesco Zaja, Annalisa Chiarenza, MD PhD, Giovanni Del Poeta, MD, Antonella Zucchetto, PhD, Francesca Maria Rossi, PhD, Ilaria Del Giudice, MD PhD, Paolo Sportoletti, MD, Roberto Marasca, MD, Paolo Ghia, MD PhD, Robin Foà, MD, Gianluca Gaidano, Davide Rossi, MD PhD, Valter Gattei, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-136389
Published: 2020