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Journal Articles

CSF3R T618I Is Stabilized By Calnexin and Induces Unfolded Protein Response (UPR) and ER-Phagy: A Pro-Survival Pathway for Oncogenic Misfolded CSF3R Proteins in Chronic Neutrophilic Leukemia (CNL)

Alessandra Hartke, Julia Klotz, Axel Künstner, Anke Fähnrich, Hauke Busch, Timo Gemoll, Jasmin Osius, Steffen Koschmieder, Tim H. H. Brummendorf, Heike L. Pahl, Florian H. Heidel, Konstanze Döhner, Martin Griesshammer, Andreas Reiter, Justus Duyster, Nikolas C. C. von Bubnoff, Sivahari P. Gorantla

Blood (2024) 144 (Supplement 1): 1348.

https://doi.org/10.1182/blood-2024-202513

Published: 2024

Journal Articles

Guiding Treatment and Clinical Management of Patients with CNS Lymphomas By Minimal-Invasive Detection of Circulating Tumor DNA in Cerebrospinal Fluid

Blood (2024) 144 (Supplement 1): 1583.

https://doi.org/10.1182/blood-2024-202943

Published: 2024

Journal Articles

SPARC Stabilizes Integrin α4-VCAM-1 Interactions and Is Regulated By Intracellular Rac in NPM1 -Mutated AML

Driti Ashok, Dennis Raith, Martin Helmstädter, Geoffroy Andrieux, Séverine Kayser, Sangya Chatterjee, Judith Treiber, Khalid Shoumariyeh, Tim Struessmann, Valentin Wenger, Julian Rapp, Jesus Duque Afonso, Michael Lübbert, Robert Zeiser, Melanie Boerries, Justus Duyster, Tanja Nicole Hartmann

Blood (2024) 144 (Supplement 1): 1298.

https://doi.org/10.1182/blood-2024-205323

Published: 2024

Journal Articles

Machine Learning Based Prediction of One Year Mortality after Allogeneic Hematopoietic Cell Transplantation (alloHCT) Highlights Importance of Pre-Transplant Immunocompetence

Thomas Meyer, Robert Meyer, Daniela Oelke, Ralph Wäsch, Justus Duyster, Jürgen Finke, Robert Zeiser, Claudia Wehr

Blood (2024) 144 (Supplement 1): 106.

https://doi.org/10.1182/blood-2024-199021

Published: 2024

Journal Articles

Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas

Blood (2024) 144 (Supplement 1): 856.

https://doi.org/10.1182/blood-2024-199257

Published: 2024

Journal Articles

The Effect of Ibrutinib on the Myeloid Cell Compartment in Central Nervous System Lymphoma Slice Cultures

Julia C. Kuehn, Nicolas N. Neidert, Junyi Zhang, Jurik A Mutter, Stefan K. Alig, Christian Klingler, Fabian Hummel, Sabine Bleul, Lavanya Ranganathan, Jürgen Beck, Marco Prinz, Maximilian Diehn, Ash A. Alizadeh, Justus Duyster, Roman Sankowski, Dieter Henrik Heiland, Florian Scherer

Blood (2024) 144 (Supplement 1): 4374.

https://doi.org/10.1182/blood-2024-199125

Published: 2024

Journal Articles

Identification of Ikaros As Novel Interaction Partner of Cyclin D1/CDK4 in MCL

Xiaoyang Sun, Stephan de Bra, Tatjana Schmitz, Stefan Tholen, Geoffroy Andrieux, Uta Sabine Sabine Martens, Melanie Boerries, Oliver Schilling, Justus Duyster, Cornelius Miething

Blood (2024) 144 (Supplement 1): 4365.

https://doi.org/10.1182/blood-2024-210877

Published: 2024

Journal Articles

FLT3-ITD Driven CMTM6 Expression Contributes to Immune Escape of Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 3392.

https://doi.org/10.1182/blood-2024-201449

Published: 2024

Journal Articles

SMARCC1 Controls the Oncogenic NOTCH1 Transcriptional Program in T-Cell Acute Lymphoblastic Leukemia

Khalid Shoumariyeh, Xiaoyang Sun, Teresa Poggio, Geoffroy Andrieux, Tatjan Schmitz, Stephan de Bra, Omid Fotouhi, Sheikh Nizamuddin, Uta Sabine Sabine Martens, Justus Duyster, Marc Timmers, Melanie Boerries, Cornelius Miething

Blood (2024) 144 (Supplement 1): 5760.

https://doi.org/10.1182/blood-2024-210721

Published: 2024

Journal Articles

Elevating AML Treatment: Enhancing DNMT1 Inhibition Boosts HMA Therapy

Uta Sabine Martens, Desiree Melanie Redhaber, Geoffroy Andrieux, Usama-Ur Rehman, Michael Lübbert, Justus Duyster, Cornelius Miething

Blood (2024) 144 (Supplement 1): 5746.

https://doi.org/10.1182/blood-2024-210326

Published: 2024

Journal Articles

STAT5-Activating Oncogenes Drive Oncostatin M Production Causing T Cell Exhaustion and Suppressive Myeloid Cell Recruitment

Blood (2024) 144 (Supplement 1): 4119.

https://doi.org/10.1182/blood-2024-207654

Published: 2024

Journal Articles

Early Prediction of Treatment Response By Circulating Tumor DNA Profiling in Patients with Diffuse Large B-Cell Lymphoma Receiving CAR T-Cell Therapy

Anna Katharina Foerster, Corinna Kronenthaler, Lavanya Ranganathan, Samuel Bandara, Corinna Woestmann, Stephanie Yaung, Sabine Bleul, Christian Klingler, Jan Mitschke, Julius Wehrle, Ralph Wäsch, Justus Duyster, Tim Struessmann, Jürgen Finke, Bowdoin Su, Reinhard Marks, Florian Scherer

Blood (2023) 142 (Supplement 1): 2987.

https://doi.org/10.1182/blood-2023-178871

Published: 2023

Journal Articles

The Integrin Adaptor Kindlin-3 Is a Gatekeeper for Germinal Center Responses and the Development of Chronic Lymphocytic Leukemia

Lixia Li, Andrea Härzschel, Peter Krenn, Danielle-Justine Danner, Laura Polcik, Adrián Fernández-Rego, Jennifer Schönbeck, Melissa Riedle, Sandra Kissel, Cornelius Miething, Justus Duyster, Natalie Koehler, Susanna Fagerholm, Yolanda Carrasco, Palash Maity, Tanja Nicole Hartmann

Blood (2023) 142 (Supplement 1): 82.

https://doi.org/10.1182/blood-2023-181755

Published: 2023

Journal Articles

CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model

Blood (2023) 142 (Supplement 1): 81.

https://doi.org/10.1182/blood-2023-179726

Published: 2023

Journal Articles

Single-Center Experience of Decitabine/Venetoclax in Newly Diagnosed Older AML Patients with Non-Favorable Genetics: Bridging to Allo-HCT or Treatment Continuation

David Alber, Christoph Rummelt, Tim Strüßmann, Andrés Rettig, Valeria Shlyakhto, Paul La Rosée, Martin Henkes, Elizaveta Bubnova, Tobias Ma, Johanna Thomas, Gabriele Ihorst, Claudia Wehr, Reinhard Marks, Heiko Becker, Justus Duyster, Ralph Wäsch, Jürgen Finke, Michael Lübbert

Blood (2023) 142 (Supplement 1): 7091.

https://doi.org/10.1182/blood-2023-187581

Published: 2023

Journal Articles

Long-Term Follow-up of AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation after Primary Induction Failure

Miriam Mozaffari Jovein, Gabriele Ihorst, Jesus Duque Afonso, Ralph Wäsch, Claudia Wehr, Hartmut Bertz, Justus Duyster, Robert Zeiser, Jürgen Finke, Florian Scherer

Blood (2023) 142 (Supplement 1): 3588.

https://doi.org/10.1182/blood-2023-179103

Published: 2023

Journal Articles

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Henrike Salié, Dimitrios Athanassopoulos, Lukas Braun, Dominik Schmidt, Viktor Fetsch, Rebeka N. Javorniczky, Jenny N.H.G Ho, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian Capitini, Terry J. Fry, Thomas Blank, Bruce R Blazar, Eva-Maria Wagner Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp Tobias Meyer, Joachim Brumberg, Andreas Mackensen, Michael von Bergwelt-Baildon, Roland Coras, Nathalie L. Albert, Laura M. Bartos, Matthias Brendel, Adrien Holzgreve, Melanie Boerries, Crystal L. Mackall, Justus Duyster, Natalie Koehler, Felix Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser

Blood (2023) 142 (Supplement 1): 100.

https://doi.org/10.1182/blood-2023-184867

Published: 2023

Journal Articles

Genetic and Epigenetic Changes at Secondary Resistance after Continued Treatment in the Randomized Phase II Study of All- Trans Retinoic Acid (ATRA) and/or Valproic Acid (VPA) Added to Decitabine (DAC) in Newly Diagnosed Elderly AML Patients (DECIDER Trial)

Inga Hund, Maria Hess, Julia Stomper, Gabriele Greve, Jan Mitschke, Christoph Niemöller, Tobias Ma, David Uhl, Felicitas R. Thol, Michael Heuser, Gesine Bug, Martina Crysandt, Lutz Peter Mueller, Andreas Neubauer, Justus Duyster, Hartmut Dohner, Melanie Boerries, Heiko Becker, Michael Luebbert

Blood (2022) 140 (Supplement 1): 3383–3384.

https://doi.org/10.1182/blood-2022-163220

Published: 2022

Journal Articles

Establishment and Characterization of Mouse Models with Primary and Acquired BTK Inhibitor Resistance

Laura Polcik, Svenja Dannewitz Prosseda, Chingiz Underbayev, Geoffroy Andrieux, Lixia Li, Danielle-Justine Danner, Driti Ashok, Sandra Kissel, Sara Parsa, Natalie Koehler, Melanie Börries, Justus Duyster, Elena Bibikova, Adrian Wiestner, Tanja Nicole Hartmann

Blood (2022) 140 (Supplement 1): 4109–4110.

https://doi.org/10.1182/blood-2022-164662

Published: 2022

Journal Articles

High-Dose Chemotherapy and Autologous Stem Cell Transplant in Elderly and Fit Primary CNS Lymphoma Patients - a Multicenter Study By the Cooperative PCNSL Study Group (MARTA study)

Blood (2022) 140 (Supplement 1): 1773–1774.

https://doi.org/10.1182/blood-2022-162157

Published: 2022

NARROW

CSF3R T618I Is Stabilized By Calnexin and Induces Unfolded Protein Response (UPR) and ER-Phagy: A Pro-Survival Pathway for Oncogenic Misfolded CSF3R Proteins in Chronic Neutrophilic Leukemia (CNL)

Guiding Treatment and Clinical Management of Patients with CNS Lymphomas By Minimal-Invasive Detection of Circulating Tumor DNA in Cerebrospinal Fluid

SPARC Stabilizes Integrin α4-VCAM-1 Interactions and Is Regulated By Intracellular Rac in NPM1 -Mutated AML

Machine Learning Based Prediction of One Year Mortality after Allogeneic Hematopoietic Cell Transplantation (alloHCT) Highlights Importance of Pre-Transplant Immunocompetence

Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas

The Effect of Ibrutinib on the Myeloid Cell Compartment in Central Nervous System Lymphoma Slice Cultures

Identification of Ikaros As Novel Interaction Partner of Cyclin D1/CDK4 in MCL

FLT3-ITD Driven CMTM6 Expression Contributes to Immune Escape of Acute Myeloid Leukemia

SMARCC1 Controls the Oncogenic NOTCH1 Transcriptional Program in T-Cell Acute Lymphoblastic Leukemia

Elevating AML Treatment: Enhancing DNMT1 Inhibition Boosts HMA Therapy

STAT5-Activating Oncogenes Drive Oncostatin M Production Causing T Cell Exhaustion and Suppressive Myeloid Cell Recruitment

Early Prediction of Treatment Response By Circulating Tumor DNA Profiling in Patients with Diffuse Large B-Cell Lymphoma Receiving CAR T-Cell Therapy

The Integrin Adaptor Kindlin-3 Is a Gatekeeper for Germinal Center Responses and the Development of Chronic Lymphocytic Leukemia

CD49d Shapes B Cell Receptor Responsiveness and Tissue Distribution in an Aggressive Chronic Lymphocytic Leukemia Murine Model

Single-Center Experience of Decitabine/Venetoclax in Newly Diagnosed Older AML Patients with Non-Favorable Genetics: Bridging to Allo-HCT or Treatment Continuation

Long-Term Follow-up of AML Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation after Primary Induction Failure

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

Genetic and Epigenetic Changes at Secondary Resistance after Continued Treatment in the Randomized Phase II Study of All- Trans Retinoic Acid (ATRA) and/or Valproic Acid (VPA) Added to Decitabine (DAC) in Newly Diagnosed Elderly AML Patients (DECIDER Trial)

Establishment and Characterization of Mouse Models with Primary and Acquired BTK Inhibitor Resistance

High-Dose Chemotherapy and Autologous Stem Cell Transplant in Elderly and Fit Primary CNS Lymphoma Patients - a Multicenter Study By the Cooperative PCNSL Study Group (MARTA study)

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American Society of Hematology

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American Society of Hematology

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