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Tobias Berg
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Journal Articles

The Transcription Factor IRF8 Regulates the Sensitivity of AML Cells to LSD1 Inhibition and All-Trans Retinoic Acid

Emily E Hartung, Kanwaldeep Singh, Sarah Coopersmith, Jamie Avrumutsoae, Siddaarth Varatharajan, Sara Pishyar, Pradhariny Prabagaran, Dina Khalaf, Alejandro Garcia-Horton, Ronan Foley, Brian Leber, Irwin Walker, Kylie L. Lepic, Maria Kleppe, Hugh Young Rienhoff, Jr., Tobias Berg
Journal: Blood
Blood (2024) 144 (Supplement 1): 2764.
https://doi.org/10.1182/blood-2024-199648
Published: 2024
Journal Articles

Analysis of the Impact of Whole Blood and T-Cell Donor Chimerism after Allogeneic Stem Cell Transplant

Michael Radford, Alejandro Garcia-Horton, Rohail Badami, Elaine Jin, Nida Javed Usmani, Daria Grafodatskaya, Elizabeth McCready, Dina Khalaf, Irwin Walker, Brian Leber, Kylie L. Lepic, Gregory Pond, Tobias Berg
Journal: Blood
Blood (2023) 142 (Supplement 1): 2211.
https://doi.org/10.1182/blood-2023-187458
Published: 2023
Journal Articles

LSD1 Inhibition Enhances Antigen Presentation and Co-Stimulation in AML to Promote T Cell-Mediated Anti-Leukemia Immune Responses

Yu Yan, Kanwaldeep Singh, Emily Hartung, Brendan Lee, Pradhariny Prabagaran, Dina Khalaf, Alejandro Garcia-Horton, Brian Leber, Irwin Walker, Kylie L. Lepic, Maria Kleppe, Hugh Young Young Rienhoff Jr., Jr., Jonathan Bramson, Tobias Berg
Journal: Blood
Blood (2023) 142 (Supplement 1): 6793.
https://doi.org/10.1182/blood-2023-188472
Published: 2023
Journal Articles

Ureaplasma -Induced Hyperammonemia Syndrome - an Acute Complication Post Allogeneic Stem Cell Transplant

Rohail Badami, Kylie L. Lepic, Dina Khalaf, Alejandro Garcia-Horton, Tobias Berg, Brian Leber, Irwin Walker, Michael Radford
Journal: Blood
Blood (2023) 142 (Supplement 1): 6988.
https://doi.org/10.1182/blood-2023-182897
Published: 2023
Journal Articles

LSD1 Inhibition Synergizes with Venetoclax in Acute Myeloid Leukemia By Targeting Cellular Metabolism

Kanwaldeep Singh, Emily Hartung, Christina Muhs, Islam Alshamleh, Monisha Divakaran, Anna Dvorkin-Gheva, Sara Pishyar, Pradhariny Prabagaran, Dina Khalaf, Alejandro Garcia-Horton, Stephen Ronan Foley, Brian Leber, Irwin Walker, Kylie Lepic, Harald Schwalbe, Hubert Serve, Maria Kleppe, Hugh Young Rienhoff, Jr., Tobias Berg
Journal: Blood
Blood (2023) 142 (Supplement 1): 4156.
https://doi.org/10.1182/blood-2023-189515
Published: 2023
Journal Articles

A Retrospective Cohort Study of Donor Cell Leukemia

Brittany Salter, Omar Raslan, Suzanne Demczuk, Brian Leber, Alejandro Garcia-Horton, Irwin Walker, Tobias Berg, Darci Butcher, Kylie L. Lepic, Elizabeth McCready, Parveen Wasi, Dina Khalaf
Journal: Blood
Blood (2022) 140 (Supplement 1): 12916–12917.
https://doi.org/10.1182/blood-2022-164643
Published: 2022
Journal Articles

Phase I Study of the LSD1 Inhibitor Tranylcypromine (TCP) in Combination with All- Trans Retinoic Acid (ATRA) and Low-Dose Cytarabine (LDAC) in Elderly, Medically Non-Fit Patients with AML or High-Risk MDS (TRANSATRA trial)

Michael Lübbert, Claudia Schmoor, Tobias Berg, Michael Kruszewski, Marcus Matthias Schittenhelm, Katharina Götze, Caroline Pabst, Andrea Kündgen, Tobias Ma, Anna Frey, Kevin Moschallski, Usama-Ur Rehman, Johannes Jung, Justus Duyster, Manfred Jung, Roland Schüle, Ralph Wäsch, Olga Grishina
Journal: Blood
Blood (2022) 140 (Supplement 1): 9087–9088.
https://doi.org/10.1182/blood-2022-159471
Published: 2022
Journal Articles

Fitness Assessment of Elderly Patients with AML and Outcomes

Tony HT Chen, Joshua Xu, Hassan Zahreddine, Brian Leber, Irwin Walker, Tobias Berg, Kylie L. Lepic, Parveen Wasi, Tom Kouroukis, Christopher M. Hillis, Justin Y. Lee, Dina Khalaf
Journal: Blood
Blood (2021) 138 (Supplement 1): 3379.
https://doi.org/10.1182/blood-2021-152612
Published: 2021
Journal Articles

Identification of Prognostic Immunophenotypes at First Diagnosis in Patients with Acute Myeloid Leukemia (AML) By a Standardized Multicolor Flow Cytometry (MFC) Panel Originally Designed to Detect Measurable Residual Disease (MRD) at Follow-up

Maximilian Alexander A Rohnert, Malte von Bonin, Michael Kramer, Philipp Ensel, Nadja Holtschke, Christoph Rollig, MD MSC, Martin Bornhäuser, MD, Veit Buecklein, MD, Marion Subklewe, MD, Stefan W Krause, Simon Voelkl, Tobias Berg, Michael A Rieger, Cornelia Brendel, Jörg Hoffmann, Nicole Hofmeister-Mielke, Richard F. Schlenk, Sylvie D Freeman, Uta Oelschlägel
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-138683
Published: 2020
Journal Articles

Impact of KIR/HLA Incompatibilities after Posttransplant Cyclophosphamide Based T Cell-Replete Haploidentical Hematopoietic Stem Cell Transplantation

Sarah Lindner, MD, Tobias Berg, MD, Christian Seidel, Franziska Kalensee, Michael A. Rieger, Hubert Serve, MD, Gesine Bug, Joachim Schwaeble, Evelyn Ullrich, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3340.
https://doi.org/10.1182/blood-2019-125243
Published: 2019
Journal Articles

Sorafenib As Maintenance Therapy Post Allogeneic Stem Cell Transplantation for FLT3-ITD Positive AML: Results from the Randomized, Double-Blind, Placebo-Controlled Multicentre Sormain Trial

Andreas Burchert, MD, Gesine Bug, Jürgen Finke, MD, Matthias Stelljes, MD, Christoph Rollig, MD MSC, Ralph Wäsch, MD, Martin Bornhäuser, Tobias Berg, MD, Fabian Lang, MD, Gerhard Ehninger, MD, Hubert Serve, MD, Robert Zeiser, MD, Eva-Maria Wagner, MD, Nicolaus Kroeger, Christine Wolschke, MD, Michael Schleuning, MD, Ahmet Elmaagacli, Katharina S. Götze, MD, Christoph Schmid, MD, Edgar Jost, MD, Dominik Wolf, Alexandra Böhm, MD, Christian Thiede, MD, Torsten Haferlach, MD, Wolfgang Bethge, MD, Susanne Harnisch, Dipl. Humanbiol., Michael Wittenberg, PhD, Susanne Rospleszcz, Andreas Neubauer, Markus Brugger, Konstantin Strauch, PhD, Carmen Schade-Brittinger, Stephan K Metzelder, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 661.
https://doi.org/10.1182/blood-2018-99-112614
Published: 2018
Journal Articles

Impact of Donor Chimerism-Guided Immunomodulation after Allogeneic Stem Cell Transplant on the Outcome of Patients with AML and MDS

Juliane Steinmann, Sarah Lindner, MD, Zuzana Jedlickova, MD, Salem Ajib, MD, Saskia C. Gueller, MD, Tobias Berg, MD, Julia Riemann, MD, Fabian Lang, MD, Rosa Toenges, MD, Hans Martin, MD, Michael Kramer, M.Sc., Johannes Schetelig, MD MSc, Hubert Serve, MD, Christian Thiede, MD, Gesine Bug
Journal: Blood
Blood (2018) 132 (Supplement 1): 2133.
https://doi.org/10.1182/blood-2018-99-116088
Published: 2018
Journal Articles

LSD1 Inhibition Leads to Differentiation in Hoxa9/Meis1- but Not in MN1-Induced Acute Myeloid Leukemia

Jessica Barth, Anna-Maria Scheder, Sebastian Mohr, Johannes Schulz-Fincke, Martin Schmitt, PhD, Alexandra Walter, Milica Tosic, Eric Metzger, Gesine Bug, MD, Michael Lübbert, Manfred Jung, PhD, Hubert Serve, Roland Schüle, PhD, Tobias Berg, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1246.
https://doi.org/10.1182/blood.V130.Suppl_1.1246.1246
Published: 2017
Journal Articles

LSD1 Inhibition Induces Differentiation and Reduces the Frequency of Leukemia-Initiating Cells in Hoxa9/Meis1-Induced Acute Myeloid Leukemia

Jessica Barth, Anna-Maria Scheder, Sebastian Mohr, Schulz-Fincke Johannes, Martin Schmitt, Alexandra Walter, Milica Tosic, Eric Metzger, Michael Lübbert, MD, Manfred Jung, PhD, Hubert Serve, MD, Roland Schüle, Tobias Berg, MD
Journal: Blood
Blood (2016) 128 (22): 3935.
https://doi.org/10.1182/blood.V128.22.3935.3935
Published: 2016
Journal Articles

Ibrutinib for Bridging to Allogeneic Hematopoietic Stem Cell Transplantation (alloHCT) in Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL) Is Safe and Effective: First Results of a Survey By the Chronic Malignancy and the Lymphoma Working Parties of the EBMT

Peter Dreger, MD, Mauricette Michallet, MD PhD, Jennifer Hoek, Data Manager, Ariane Boumendil, PhD, Mohamad Sobh, PharmD, Lutz Muller, MD, Elisabeth A. Vandenberghe, MB, MRCPI, MRCPath, PhD, Ilaria Scortechini, MD, Niels S. Andersen, MD PhD, Jurgen Finke, MD, Domenico Russo, MD, Jakob R Passweg, MD, Helene Schoemans, MD, Nadira Durakovic, MD PhD, Helene Labussiere, MD, Tobias Berg, MD, Dietger Niederwieser, MD, Wolfgang Bethge, MD, Nicola Mordini, MD, Michel van Gelder, MD PhD, Nicolaas PM Schaap, MD PhD, Nicolaus Kroger, MD PhD, Silvia Montoto, MD, Johannes Schetelig, MD MSc
Journal: Blood
Blood (2016) 128 (22): 4657.
https://doi.org/10.1182/blood.V128.22.4657.4657
Published: 2016
Journal Articles

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia

Sebastian Mohr, Carmen Doebele, PhD, Tobias Berg, MD, Federico Comoglio, PhD, Julia Beck, PhD, Gabriela Alexe, PhD, Jasmin Corso, Hanibal Bohnenberger, MD, Philipp Stroebel, MD, Astrid Wachter, Tim Beissbarth, PhD, Frank Schnuetgen, PhD, Nadine Haetscher, PhD, Stefanie Goellner, PhD, Arefeh Rouhi, PhD, Lars Palmqvist, MD PhD, Michael A Rieger, PhD, Carsten Mueller-Tidow, MD, Florian Kuchenbauer, Ekkehardt Schuetz, MD, Henning Urlaub, PhD, Kimberly Stegmaier, MD, R. Keith Humphries, MD PhD, Hubert Serve, MD, Thomas Oellerich, MD
Journal: Blood
Blood (2016) 128 (22): 1533.
https://doi.org/10.1182/blood.V128.22.1533.1533
Published: 2016
Journal Articles

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Brief Report
Suzan Imren, Michael Heuser, Maura Gasparetto, Philip A. Beer, Gudmundur L. Norddahl, Ping Xiang, Ling Chen, Tobias Berg, Garrett W. Rhyasen, Patricia Rosten, Gyeongsin Park, Yeonsook Moon, Andrew P. Weng, Connie J. Eaves, R. Keith Humphries
Journal: Blood
Blood (2014) 124 (24): 3608–3612.
https://doi.org/10.1182/blood-2014-04-564666
Published: 2014
Includes: Supplemental data
Journal Articles

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis

Tobias Berg, Silvia Thoene, Damian Yap, Tracee Wee, Nathalie Schoeler, Patty Rosten, Emilia Lim, Misha Bilenky, Andrew J. Mungall, Thomas Oellerich, Sherry Lee, Courteney K. Lai, Patricia Umlandt, Anisa Salmi, Harry Chang, Lisa Yue, David Lai, S.-W. Grace Cheng, Ryan D. Morin, Martin Hirst, Hubert Serve, Marco A. Marra, Gregg B. Morin, Randy D. Gascoyne, Samuel A. Aparicio, R. Keith Humphries
Journal: Blood
Blood (2014) 123 (25): 3914–3924.
https://doi.org/10.1182/blood-2012-12-473439
Published: 2014
Includes: Supplemental data
Journal Articles

Characterization Of The Effects Of Mutated EZH2 On Expression and Epigenome In a Mouse Lymphoma Model

Tobias Berg, MD, Silvia Thoene, PhD, Damian Yap, PhD, Tracee Wee, Nathalie Schoeler, Patty Rosten, Emilia Lim, Misha Bilenky, Andrew J Mungall, Ph.D., Thomas Oellerich, Patricia Umlandt, Anisa Salmi, Harry Chang, Lisa Yue, David Lai, Grace Cheng, PhD, Hubert Serve, MD, Ryan D Morin, Martin Hirst, Marco A. Marra, PhD, Gregg B. Morin, PhD, Randy D. Gascoyne, MD, Samuel A. Aparicio, PhD, R. Keith Humphries, PhD
Journal: Blood
Blood (2013) 122 (21): 346.
https://doi.org/10.1182/blood.V122.21.346.346
Published: 2013
Journal Articles

β 2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis

Thomas Oellerich, Mark F. Oellerich, Michael Engelke, Silvia Münch, Sebastian Mohr, Marika Nimz, He-Hsuan Hsiao, Jasmin Corso, Jing Zhang, Hanibal Bohnenberger, Tobias Berg, Michael A. Rieger, Jürgen Wienands, Gesine Bug, Christian Brandts, Henning Urlaub, Hubert Serve
Journal: Blood
Blood (2013) 121 (19): 3889–3899.
https://doi.org/10.1182/blood-2012-09-457887
Published: 2013
Includes: Supplemental data