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Journal Articles

The POLARIX Study: Polatuzumab Vedotin with Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (pola-R-CHP) Versus Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) Therapy in Patients with Previously Untreated Diffuse Large B-Cell Lymphoma

Hervé Tilly, Franck Morschhauser, Laurie H. Sehn, Jonathan W. Friedberg, Marek Trněný, Jeff P. Sharman, Charles Herbaux, John M. Burke, Matthew Matasar, Shinya Rai, Koji Izutsu, Neha Mehta-Shah, Lucie Oberic, Adrien Chauchet, Wojciech Jurczak, Yuqin Song, Richard Greil, Larysa Mykhalska, Juan Miguel Bergua Burgués, Matthew C. Cheung, Antonio Pinto, Ho-Jin Shin, Greg Hapgood, Eduardo Munhoz, Pau Abrisqueta Costa, Jyh-Pyng Gau, Jamie Hirata, Yanwen Jiang, Mark Yan, Calvin Lee, Christopher R. Flowers, Gilles Salles
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-1.
DOI: https://doi.org/10.1182/blood-2021-154729
Published: 2021
Journal Articles

The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis

Margarete A Fabre, Jose Guillherme de Almeida, Edoardo Fiorillo, Emily Mitchell, Aristi Damaskou, Justyna Rak, Valeria Orru, Michele Marongiu, MS Vijayabaskar, Joanna E Baxter, Claire Hardy, Federico Abascal, Michael Spencer Chapman, Nicholas Williams, Jyoti Nangalia, Inigo Martincorena, Peter J Campbell, Eoin F Mckinney, Francesco Cucca, Moritz Gerstung, George S Vassiliou
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-2.
DOI: https://doi.org/10.1182/blood-2021-154938
Published: 2021
Journal Articles

Fitusiran, an Investigational siRNA Therapeutic Targeting Antithrombin for the Treatment of Hemophilia: First Results from a Phase 3 Study to Evaluate Efficacy and Safety in People with Hemophilia a or B without Inhibitors (ATLAS-A/B)

Alok Srivastava, Savita Rangarajan, Kaan Kavakli, Robert Klamroth, Gili Kenet, Liane Khoo, Chur-Woo You, Weiqun Xu, Niel Malan, Laurent Frenzel, Catherine N. Bagot, Oleksandra Stasyshyn, Chia-Yau Chang, Stacey Poloskey, Shauna Andersson, Zhiying Qiu, Baisong Mei, Steven W. Pipe
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-3.
DOI: https://doi.org/10.1182/blood-2021-155018
Published: 2021
Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan Martin Barajas, Melvin Edward Thomas, III, Michael P Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott Foy, Jamie L. Maciaszek, Andrew B Kleist, Amanda R. Leonti, Bensheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marc Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley B Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-4.
DOI: https://doi.org/10.1182/blood-2021-155134
Published: 2021
Journal Articles

Efficacy of rFVIIIFc for First-Time Immune Tolerance Induction (ITI) Therapy: Final Results from the Global, Prospective VerITI-8 Study

Lynn Malec, An Van Damme, Anthony Chan, Mariya Spasova, Nisha Jain, Charlotte Sensinger, Jennifer Dumont, Stefan Lethagen, Manuel Carcao, Flora Peyvandi
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-5.
DOI: https://doi.org/10.1182/blood-2021-155156
Published: 2021
Journal Articles

Tisagenlecleucel Vs Standard of Care As Second-Line Therapy of Primary Refractory or Relapsed Aggressive B-Cell Non-Hodgkin Lymphoma: Analysis of the Phase III Belinda Study

Michael R. Bishop, Michael Dickinson, Duncan Purtill, Pere Barba, Armando Santoro, Nada Hamad, Koji Kato, Anna Sureda, Richard Greil, Catherine Thieblemont, Franck Morschhauser, Martin Janz, Ian W. Flinn, Werner Rabitsch, Yok Lam Kwong, Marie José Kersten, Monique C. Minnema, Harald Holte, Esther Hian Li Chan, Joaquin Martinez-Lopez, Antonia MS Mueller, Richard T. Maziarz, Joseph P. McGuirk, Emmanuel Bachy, Steven Le Gouill, Martin Dreyling, Hideo Harigae, David A. Bond, Charalambos Andreadis, Peter A. McSweeney, Mohamed A. Kharfan-Dabaja, Simon Newsome, Evgeny Degtyarev, Chris Del Corral, Giovanna Andreola, Aisha Masood, Stephen J Schuster, Ulrich Jaeger, Peter Borchmann, Jason R. Westin
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-6.
DOI: https://doi.org/10.1182/blood-2021-155068
Published: 2021
Journal Articles

Code Status Transitions in Patients with High-Risk Acute Myeloid Leukemia (AML)

Hannah R. Abrams, Ryan D. Nipp, Lara Traeger, Mitchell W. Lavoie, Matthew J. Reynolds, Thomas W. LeBlanc, Areej El-Jawahri
Journal: Blood
Blood (2021) 138 (Supplement 1): 109.
DOI: https://doi.org/10.1182/blood-2021-146451
Published: 2021
Journal Articles

Frailty Scale for Outcome Predictions in Hematopoietic Cell Transplanted Adults

Maria Queralt Salas, Eshetu G Atenafu, Eshrak Al-Shaibani, Ora Bascom, Leeann Wilson, Carol Chen, Ivan Pasic, Arjun Law, Wilson Lam, Dennis Dong Hwan Kim, Armin Gerbitz, Auro Viswabandya, Jeffrey H. Lipton, Fotios Michelis, Jonas Mattsson, Shabbir Alibhai, Rajat Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 110.
DOI: https://doi.org/10.1182/blood-2021-153710
Published: 2021
Journal Articles

Race-Ethnic Enrollment Disparities over 15 Years of Alliance/CALGB Acute Myeloid Leukemia Clinical Trials, Biobanks, and Correlative Science Protocols

Andrew Hantel, Jessica Kohlschmidt, Ann-Kathrin Eisfeld, Wendy Stock, Sawyer Jacobson, Sumithra J Mandrekar, Richard M. Stone, Daniel J. DeAngelo, John C. Byrd, Gregory A. Abel
Journal: Blood
Blood (2021) 138 (Supplement 1): 111.
DOI: https://doi.org/10.1182/blood-2021-146607
Published: 2021
Journal Articles

Cost Effectiveness Analysis of Venetoclax Plus Azacitidine Versus Azacitidine in Newly Diagnosed Adult Patients with Acute Myeloid Leukemia Who Are Ineligible for Intensive Chemotherapy from a United States Payer Perspective

Keith W. Pratz, Xinglei Chai, Jipan Xie, Lei Yin, Xiaoyu Nie, Melissa Montez, Erica Iantuono, Lisa Downs, Esprit Ma
Journal: Blood
Blood (2021) 138 (Supplement 1): 112.
DOI: https://doi.org/10.1182/blood-2021-148338
Published: 2021
Journal Articles

Cost-Effectiveness of Liposomal Cytarabine-Daunorubicin (CPX-351) Compared to Conventional Cytarabine-Daunorubicin Chemotherapy in Acute Myeloid Leukemia

Jan Philipp Bewersdorf, George Goshua, Kishan K Patel, Rory M. Shallis, Nikolai Podoltsev, Scott F. Huntington, Amer M. Zeidan
Journal: Blood
Blood (2021) 138 (Supplement 1): 113.
DOI: https://doi.org/10.1182/blood-2021-144992
Published: 2021
Journal Articles

The Sustainability of Price Dynamics in Precision Hematology

Caleb J Scheckel, Aakash Desai, Chelsee Jensen, Jacob Orme, Nandita Khera, Joshua C. Pritchett, Amit Mahipal, Ronald Go
Journal: Blood
Blood (2021) 138 (Supplement 1): 114.
DOI: https://doi.org/10.1182/blood-2021-152715
Published: 2021
Journal Articles

The Accuracy of the International Myeloma Working Group Frailty Score in Capturing Health-Related Quality of Life Profile of Patients with Relapsed Refractory Multiple Myeloma

Fabio Efficace, Gianluca Gaidano, Maria Teresa Petrucci, Pasquale Niscola, Lucia Tognazzi, Elisabetta Antonioli, Francesco Cottone, Ombretta Annibali, Agostino Tafuri, Catello Califano, Alessandra Larocca, Leonardo Potenza, Giulia Palazzo, Claudio Fozza, Domenico Pastore, Gian Matteo Rigolin, Massimo Offidani, Alessandra Romano, Patrizia Tosi, Charalampia Kyriakou, Nicola Cascavilla, Stefano Molica, Alessandro Gozzetti, Daniele Derudas, Marco Vignetti, Michele Cavo
Journal: Blood
Blood (2021) 138 (Supplement 1): 115.
DOI: https://doi.org/10.1182/blood-2021-145977
Published: 2021
Journal Articles

Is Symptom Burden Associated with Health Care Utilization: A Longitudinal Population-Based Cohort Study of Transplant Ineligible Patients with Newly Diagnosed Multiple Myeloma

Hira S Mian, Rinku Sutradhar, Gregory R Pond, Branavan Sivapathasundaram, Anita D'Souza, Tanya M. Wildes, Hsien Seow
Journal: Blood
Blood (2021) 138 (Supplement 1): 116.
DOI: https://doi.org/10.1182/blood-2021-146862
Published: 2021
Journal Articles

Real-World Treatment Patterns and Clinical, Economic, and Humanistic Burden in Triple-Class Refractory Multiple Myeloma: Analysis of the Connect ® Multiple Myeloma (MM) Disease Registry

Derek Tang, Parameswaran Hari, Karthik Ramasamy, Katja Weisel, Prashant Joshi, Liang Liu, Min Che, Gabriela Hernandez, Rafat Abonour, James W. Hardin, Robert M. Rifkin, Sikander Ailawadhi, Hans C. Lee, Howard R. Terebelo, Brian G.M. Durie, Mohit Narang, Kathleen Toomey, Cristina Gasparetto, Lynne I. Wagner, Sundar Jagannath
Journal: Blood
Blood (2021) 138 (Supplement 1): 117.
DOI: https://doi.org/10.1182/blood-2021-146830
Published: 2021
Journal Articles

First-Line Use of Daratumumab, Lenalidomide, and Dexamethasone Confers Survival Benefit Compared with Second-Line Use of Daratumumab-Based Regimens in Transplant-Ineligible Patients with Multiple Myeloma: Analysis of Different Clinical Scenarios

Rafael Fonseca, Thierry Facon, Mahmoud Hashim, Sandhya Nair, Jianming He, Eric M. Ammann, Annette Lam, Mark Wildgust, Shaji Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 118.
DOI: https://doi.org/10.1182/blood-2021-144914
Published: 2021
Journal Articles

Mortality Trends in Multiple Myeloma after the Introduction of Novel Therapies in the United States

Bharat Nandakumar, Moritz Binder, S. Vincent Rajkumar, Prashant Kapoor, Francis K. Buadi, David Dingli, Martha Q. Lacy, Morie A. Gertz, Suzanne R. Hayman, Nelson Leung, Amie Fonder, Miriam A. Hobbs, Yi L. Hwa, Eli Muchtar, Rahma M Warsame, Taxiarchis Kourelis, Wilson I Gonsalves, Stephen J. Russell, Yi Lin, Mustaqeem A. Siddiqui, Robert A. Kyle, Angela Dispenzieri, Shaji Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 119.
DOI: https://doi.org/10.1182/blood-2021-146894
Published: 2021
Journal Articles

Efficacy and Long-Term Outcomes of Autologous Stem Cell Transplant (ASCT) for Patients with POEMS Syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, Skin Changes): A CIBMTR Analysis

Ankit Kansagra, Angela Dispenzieri, Raphael Fraser, Noel Estrada-Merly, Shaji Kumar, Muzaffar H. Qazilbash, Nina Shah, Anita D'Souza
Journal: Blood
Blood (2021) 138 (Supplement 1): 120.
DOI: https://doi.org/10.1182/blood-2021-151325
Published: 2021
Journal Articles

Assessment of Functional Shunting in Patients with Sickle Cell Disease

Liza Afzali-Hashemi, Lena Vaclavu, John C Wood, Aart J Nederveen, Henk J.M.M. Mutsaerts, Anouk Schrantee, Bart J. Biemond
Journal: Blood
Blood (2021) 138 (Supplement 1): 121.
DOI: https://doi.org/10.1182/blood-2021-145163
Published: 2021
Journal Articles

Defining and Predicting Rapid Egfr Decline in Sickle Cell Disease

Santosh L. Saraf, Jin Han, Maria Armila Ruiz, Andrew Srisuwananukorn, David Shuey, Faiz Ahmed Hussain, Franklin Njoku, Robert E. Molokie, Victor R. Gordeuk
Journal: Blood
Blood (2021) 138 (Supplement 1): 122.
DOI: https://doi.org/10.1182/blood-2021-147861
Published: 2021