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Journal Articles

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Blood (2024) 144 (20): 2121–2135.

https://doi.org/10.1182/blood.2024024590

Published: 2024

Includes: Supplemental data

Journal Articles

Visualization of Bortezomib Induced Peripheral Neuropathy By Dorsal Root Ganglion MRI in Patients with Multiple Myeloma

Xiang Zhou, Magnus Schindehuette, Nadine Cebulla, Baran Öztürk, Simon Weiner, Julia Mersi, Leo Rasche, Johannes Waldschmidt, Hermann Einsele, Robert Blum, Heike Rittner, Claudia Sommer, Mirko Pham, Martin K. Kortüm

Blood (2024) 144 (Supplement 1): 7580.

https://doi.org/10.1182/blood-2024-210374

Published: 2024

Journal Articles

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Seungbin Han, Nazia Afrin, Bas Tolhuis, Marietta Truger, Peter Raab, Umair Munawar, Cornelia Vogt, Shilpa Kurian, Silvia Nerreter, Xiang Zhou, Claudia Haferlach, Hermann Einsele, Johannes Waldschmidt, Leo Rasche, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 7490.

https://doi.org/10.1182/blood-2024-207422

Published: 2024

Journal Articles

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Seungbin Han, Chien-Yun Lee, Lenka Besse, Umair Munawar, Andrej Besse, Ann-Sohpie Hainold, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Xiang Zhou, Larissa Haertle, Johannes Waldschmidt, Christoph Driessen, Hermann Einsele, Leo Rasche, Bernhard Kuster, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 6817.

https://doi.org/10.1182/blood-2024-203352

Published: 2024

Journal Articles

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Xiang Zhou, Sarah Wiethe, Angelika Wolff, Max J Steinhardt, Nazia Afrin, Mara John, Christine Riedhammer, Xianghui Xiao, Umair Munawar, Julia Mersi, Seungbin Han, Johannes Waldschmidt, Angela Riedel, Max S. Topp, Johannes Duell, Hermann Einsele, K. Martin Kortüm, Leo Rasche

Blood (2024) 144 (Supplement 1): 4705.

https://doi.org/10.1182/blood-2024-203391

Published: 2024

Journal Articles

Tracking Bone Marrow Regeneration after CAR-T Cell Therapy in Myeloma at Spatial Single-Cell Resolution Reveals Determinants of Prolonged Cytopenia

Jennifer Wing Lam Cheung, Prachurjya Panda, Xiang Zhou, Katrin Sinning, Ankit Agrawal, Andy Shing Fung Chan, Johannes Duell, Johannes Waldschmidt, Hermann Einsele, Martin Väth, Andreas Rosenwald, Dominic Grün, Leo Rasche

Blood (2024) 144 (Supplement 1): 4639.

https://doi.org/10.1182/blood-2024-203052

Published: 2024

Journal Articles

Real-World Confirmatory Analysis of the Current IMWG Diagnostic Criteria Identifies Early Transformation As Major Risk Factor in Plasma Cell Leukemia

Jessica Peter, Sophia Danhof, Xiang Zhou, Maximilian J. Steinhardt, Sven Krippner, Anna Gebauer, Franz Reinhard, Georg Fette, Maximilian Ertl, Hermann Einsele, Julia Mersi, Martin K. Kortüm, Leo Rasche, Johannes Waldschmidt

Blood (2024) 144 (Supplement 1): 6893.

https://doi.org/10.1182/blood-2024-210379

Published: 2024

Journal Articles

Safety and Efficacy of R-PAD Regimen in Patients with Severe Multiple Center Idiopathic Castleman Disease: A Retrospective Case Series

Yingting Lu, Chunrong Ying, Ligen Liu, Limin Zhao, Xuewei Jiang, Tinghua Zhang, Zhizhi Zhang, Xiang Zhou, Li Chang, Xinying Zhu, Chao Du, Li Yang

Blood (2024) 144 (Supplement 1): 6888.

https://doi.org/10.1182/blood-2024-207982

Published: 2024

Journal Articles

Safety and Efficacy of Ivosidenib Based Regimen in Patients with IDH1 Mutanted Acute Myeloid Leukemia: A Retrospective Case Series

Limin Zhao, Ligen Liu, Li Yang, Fangli Chen, Xuewei Jiang, Tinghua Zhang, Zhizhi Zhang, Xiang Zhou, Li Chang, Xinying Zhu, Chao Du, Chunrong Ying

Blood (2024) 144 (Supplement 1): 6055.

https://doi.org/10.1182/blood-2024-207516

Published: 2024

Journal Articles

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

Umair Munawar, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Patrick Eiring, Julia Weingart, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 593.

https://doi.org/10.1182/blood-2024-200593

Published: 2024

Journal Articles

Activity of CAR-T Cells and Bispecific Antibodies in Multiple Myeloma with Extramedullary Involvement

Blood (2024) 144 (Supplement 1): 3792.4.

https://doi.org/10.1182/blood-2024-206735

Published: 2024

Journal Articles

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Umair Munawar, Julia Weingart, Patrick Eiring, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Seungbin Han, Max J Steinhardt, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 3267.

https://doi.org/10.1182/blood-2024-204863

Published: 2024

Journal Articles

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Seungbin Han, Umair Munawar, Larissa Haertle, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Xiang Zhou, Max Steinhardt, Florian Eisele, Peter Raab, Marietta Truger, Sara Dorado, Santiago Barrio, Claudia Haferlach, Joaquin Martínez-López, Hermann Einsele, Leo Rasche, Johannes M Waldschmidt, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 3323.

https://doi.org/10.1182/blood-2023-181607

Published: 2023

Journal Articles

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Maximilian J Steinhardt, Patrick Eiring, Cornelia Vogt, Umair Munawar, Seungbin Han, Larissa Haertle, Silvia Nerreter, Eva Teufel, Julia Mersi, Xiang Zhou, Michael Hudecek, Joaquin Martinez-Lopez, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 1992.

https://doi.org/10.1182/blood-2023-189741

Published: 2023

Journal Articles

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Maximilian J Steinhardt, Thomas Bumm, Xiang Zhou, Umair Munawar, Seungbin Han, Julia Mersi, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Johannes M Waldschmidt

Blood (2023) 142 (Supplement 1): 6771.

https://doi.org/10.1182/blood-2023-189528

Published: 2023

Journal Articles

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Umair Munawar, Patrick Eiring, Cornelia Vogt, Larissa Haertle, Seungbin Han, Silvia Nerreter, Eva Teufel, Max Steinhardt, Xiang Zhou, Santiago Barrio, Hermann Einsele, Johannes M Waldschmidt, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 451.

https://doi.org/10.1182/blood-2023-180638

Published: 2023

Journal Articles

Prolonged Cytopenia Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Prospective Comprehensive Biomarker Study

Xiang Zhou, Vivien Wagner, Emilia Stanojkovska, Christine Riedhammer, Xianghui Xiao, Mara John, Lukas Scheller, Umair Munawar, Seungbin Han, Johannes M Waldschmidt, Max S. Topp, Johannes Duell, Hermann Einsele, Angela Riedel, Martin Kortüm, Leo Rasche

Blood (2023) 142 (Supplement 1): 95.

https://doi.org/10.1182/blood-2023-180534

Published: 2023

Journal Articles

Safety and Efficacy of Venetoclax Salvage Therapy in Relapsed/Refractory Multiple Myeloma with and without t(11;14)

Maximilian J Steinhardt, Max Bittrich, Xiang Zhou, Julia Noderer, Christine Riedhammer, Xianghui Xiao, Sophia Gawlas, Philipp Weis, Florian Eisele, Umair Munawar, Seungbin Han, Julia Mersi, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 6702.

https://doi.org/10.1182/blood-2023-189927

Published: 2023

Journal Articles

Multiomic Analysis of CD38 Expression Levels in 209 Untreated and Daratumumab-Resistant Patients

Blood (2022) 140 (Supplement 1): 4230–4231.

https://doi.org/10.1182/blood-2022-169255

Published: 2022

Journal Articles

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

Blood (2022) 140 (Supplement 1): 4226–4227.

https://doi.org/10.1182/blood-2022-168702

Published: 2022

NARROW

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Visualization of Bortezomib Induced Peripheral Neuropathy By Dorsal Root Ganglion MRI in Patients with Multiple Myeloma

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Tracking Bone Marrow Regeneration after CAR-T Cell Therapy in Myeloma at Spatial Single-Cell Resolution Reveals Determinants of Prolonged Cytopenia

Real-World Confirmatory Analysis of the Current IMWG Diagnostic Criteria Identifies Early Transformation As Major Risk Factor in Plasma Cell Leukemia

Safety and Efficacy of R-PAD Regimen in Patients with Severe Multiple Center Idiopathic Castleman Disease: A Retrospective Case Series

Safety and Efficacy of Ivosidenib Based Regimen in Patients with IDH1 Mutanted Acute Myeloid Leukemia: A Retrospective Case Series

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

Activity of CAR-T Cells and Bispecific Antibodies in Multiple Myeloma with Extramedullary Involvement

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Prolonged Cytopenia Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Prospective Comprehensive Biomarker Study

Safety and Efficacy of Venetoclax Salvage Therapy in Relapsed/Refractory Multiple Myeloma with and without t(11;14)

Multiomic Analysis of CD38 Expression Levels in 209 Untreated and Daratumumab-Resistant Patients

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

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American Society of Hematology

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American Society of Hematology

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