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Journal Articles

Novel insights in therapeutic antibody therapies using advanced microscopy techniques

Christina Verbruggen, Patrick Eiring, Max Steinhardt, Julia Weingart, Umair Munawar, Seungbin Han, Sven Neubert, Emma Besant, Cornelia Vogt, Silvia Nerreter, Shilpa Kurian, Nina Rein, Johanna Lehmann, Max Koeppel, Hermann Einsele, Johannes Waldschmidt, Markus Sauer, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 6111.

https://doi.org/10.1182/blood-2025-6111

Published: 2025

Journal Articles

Elevated NQO1 expression mediates proteasome inhibitor resistance and predicts adverse outcomes in multiple myeloma

Blood (2025) 146 (Supplement 1): 6812.

https://doi.org/10.1182/blood-2025-6812

Published: 2025

Journal Articles

NQO1 modulates CD38 surface expression in multiple myeloma

Seungbin Han, Christina Verbruggen, Silvia Nerreter, Umair Munawar, Shilpa Kurian, Emma Besant, Ann-Sophie Hainold, Cornelia Vogt, Xiang Zhou, Hermann Einsele, Leo Rasche, Markus Sauer, Johannes Waldschmidt, K. Martin Kortüm

Blood (2025) 146 (Supplement 1): 5718.

https://doi.org/10.1182/blood-2025-5718

Published: 2025

Journal Articles

An acquired immune-metabolic shift to common chemotherapy confers resistance to immunotherapies in relapsed, high-risk multiple myeloma

Blood (2025) 146 (Supplement 1): 3938.

https://doi.org/10.1182/blood-2025-3938

Published: 2025

Journal Articles

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Seungbin Han, Nazia Afrin, Bas Tolhuis, Marietta Truger, Peter Raab, Umair Munawar, Cornelia Vogt, Shilpa Kurian, Silvia Nerreter, Xiang Zhou, Claudia Haferlach, Hermann Einsele, Johannes Waldschmidt, Leo Rasche, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 7490.

https://doi.org/10.1182/blood-2024-207422

Published: 2024

Journal Articles

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Seungbin Han, Chien-Yun Lee, Lenka Besse, Umair Munawar, Andrej Besse, Ann-Sohpie Hainold, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Xiang Zhou, Larissa Haertle, Johannes Waldschmidt, Christoph Driessen, Hermann Einsele, Leo Rasche, Bernhard Kuster, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 6817.

https://doi.org/10.1182/blood-2024-203352

Published: 2024

Journal Articles

Early Detection and Monitoring of Multiple Myeloma By a Blood-Based Multi-Transcript Molecular Signature

Johannes Waldschmidt, Mark Kidd, Sophia Danhof, Martin Schreder, Ignat Drozdov, Cornelia Vogt, Hermann Einsele, Leo Rasche, Abdel Halim, Martin K. Kortüm

Blood (2024) 144 (Supplement 1): 4714.

https://doi.org/10.1182/blood-2024-209995

Published: 2024

Journal Articles

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

Umair Munawar, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Patrick Eiring, Julia Weingart, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 593.

https://doi.org/10.1182/blood-2024-200593

Published: 2024

Journal Articles

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Umair Munawar, Julia Weingart, Patrick Eiring, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Seungbin Han, Max J Steinhardt, Xiang Zhou, Markus Sauer, Hermann Einsele, Leo Rasche, Johannes Waldschmidt, K. Martin Kortüm

Blood (2024) 144 (Supplement 1): 3267.

https://doi.org/10.1182/blood-2024-204863

Published: 2024

Journal Articles

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Seungbin Han, Umair Munawar, Larissa Haertle, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Xiang Zhou, Max Steinhardt, Florian Eisele, Peter Raab, Marietta Truger, Sara Dorado, Santiago Barrio, Claudia Haferlach, Joaquin Martínez-López, Hermann Einsele, Leo Rasche, Johannes M Waldschmidt, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 3323.

https://doi.org/10.1182/blood-2023-181607

Published: 2023

Journal Articles

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Maximilian J Steinhardt, Patrick Eiring, Cornelia Vogt, Umair Munawar, Seungbin Han, Larissa Haertle, Silvia Nerreter, Eva Teufel, Julia Mersi, Xiang Zhou, Michael Hudecek, Joaquin Martinez-Lopez, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 1992.

https://doi.org/10.1182/blood-2023-189741

Published: 2023

Journal Articles

Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy

Maximilian J Steinhardt, Vladimir Cejka, Caroline Morbach, Aikaterini Papagianni, Silvia Nerreter, Cornelia Vogt, Umair Munawar, Seungbin Han, Leo Rasche, Johannes M Waldschmidt, Claudia Sommer, Stefan Störk, Hermann Einsele, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 6753.

https://doi.org/10.1182/blood-2023-189326

Published: 2023

Journal Articles

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Umair Munawar, Patrick Eiring, Cornelia Vogt, Larissa Haertle, Seungbin Han, Silvia Nerreter, Eva Teufel, Max Steinhardt, Xiang Zhou, Santiago Barrio, Hermann Einsele, Johannes M Waldschmidt, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 451.

https://doi.org/10.1182/blood-2023-180638

Published: 2023

Journal Articles

Impact of ABCB1 Promoter Methylation on PI-Resistance in Multiple Myeloma

Blood (2022) 140 (Supplement 1): 12462–12463.

https://doi.org/10.1182/blood-2022-168694

Published: 2022

Journal Articles

The T-Cell Metabolic Phenotype Is Dependent on Risk Status and Degree of PC Bone Marrow Infiltration in Multiple Myeloma

Mara John, Moutaz Helal, Lars Grundheber, Greta Mattavelli, Nazia Afrin, Xiang Zhou, Benedict Engel, Werner Schmitz, Emilia Stanojkovska, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Julia Mersi, Hermann Einsele, K. Martin Kortuem, Angela Riedel, Leo Rasche

Blood (2022) 140 (Supplement 1): 9959–9960.

https://doi.org/10.1182/blood-2022-168608

Published: 2022

Journal Articles

Multiomic Analysis of CD38 Expression Levels in 209 Untreated and Daratumumab-Resistant Patients

Blood (2022) 140 (Supplement 1): 4230–4231.

https://doi.org/10.1182/blood-2022-169255

Published: 2022

Journal Articles

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

Blood (2022) 140 (Supplement 1): 4226–4227.

https://doi.org/10.1182/blood-2022-168702

Published: 2022

Journal Articles

Advanced Risk Stratification in Multiple Myeloma Beyond Traditional FISH: The First Prospective Real-World Evidence for SKY92 Gene Expression Profiling

Blood (2022) 140 (Supplement 1): 4273–4274.

https://doi.org/10.1182/blood-2022-163848

Published: 2022

Journal Articles

Cereblon enhancer methylation and IMiD resistance in multiple myeloma

Blood (2021) 138 (18): 1721–1726.

https://doi.org/10.1182/blood.2020010452

Published: 2021

Includes: Supplemental data

Journal Articles

Mechanisms of Proteasome Inhibitor Resistance Selected By Clonal Evolution in Multiple Myeloma

Larissa Haertle, PhD, Santiago Barrio, PhD, Michal Simicek, PhD, Umair Munawar, MSc, Ricardo Sanchez, PhD MD, Max Bittrich, MD, Matteo DaVia, MD, Cornelia Vogt, MSc, Nicola Giesen, MD, Andoni Garitano-Trojaola, PhD, Silvia Nerreter, Thorsten Stuehmer, PhD, Marc S. Raab, MD, Joaquin Martinez Lopez, MD PhD, Roman Hajek, MD, Hermann Einsele, MD, Leo Rasche, MD, Thomas Haaf, MD, Martin Kortüm, MD

Blood (2019) 134 (Supplement_1): 4349.

https://doi.org/10.1182/blood-2019-130847

Published: 2019

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Novel insights in therapeutic antibody therapies using advanced microscopy techniques

Elevated NQO1 expression mediates proteasome inhibitor resistance and predicts adverse outcomes in multiple myeloma

NQO1 modulates CD38 surface expression in multiple myeloma

An acquired immune-metabolic shift to common chemotherapy confers resistance to immunotherapies in relapsed, high-risk multiple myeloma

Implementing Hifi Sequencing for Enhanced Genomic and Methylome Characterization in Multiple Myeloma

Multi-Omics Analysis of Proteasome Inhibitor Resistance in Multiple Myeloma

Early Detection and Monitoring of Multiple Myeloma By a Blood-Based Multi-Transcript Molecular Signature

Bi-Allelic GPRC5D Alterations Provide Proliferative Advantage in Presence of Talquetamab

GPRC5D Status Impacts CD38 Expression in Multiple Myeloma

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Impact of ABCB1 Promoter Methylation on PI-Resistance in Multiple Myeloma

The T-Cell Metabolic Phenotype Is Dependent on Risk Status and Degree of PC Bone Marrow Infiltration in Multiple Myeloma

Multiomic Analysis of CD38 Expression Levels in 209 Untreated and Daratumumab-Resistant Patients

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

Advanced Risk Stratification in Multiple Myeloma Beyond Traditional FISH: The First Prospective Real-World Evidence for SKY92 Gene Expression Profiling

Cereblon enhancer methylation and IMiD resistance in multiple myeloma

Mechanisms of Proteasome Inhibitor Resistance Selected By Clonal Evolution in Multiple Myeloma

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American Society of Hematology

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