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Antonio Valeri
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Journal Articles

CRISPR/Cas9 Multi-Editing Enhances CAR NK Cells Therapeutic Potential Against Multiple Myeloma

Eva Castellano, Almudena García-Ortiz, Laura Ugalde, Elena Maroto Martin, Jessica Encinas Mayoral, Raquel Oliva, Laura Garcia-Garcia, Irene Peña, Noemi Álvarez, Gonzalo Carreño, Rosa Ayala, Laura Cordoba, Alejandra Leivas, Guillermo Suñe, Beatriz Martin Antonio, Rafael Alonso Fernandez, Maria Teresa Cedena Romero, Joaquín Martínez-Lopez, Paula Rio, Antonio Valeri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3442.
https://doi.org/10.1182/blood-2024-207942
Published: 2024
Journal Articles

Epigenetic Modifications As a Mechanism of Resistance to BCMA-Directed Immunotherapies in Multiple Myeloma: Insights from Multi-Omic Profiling

Larissa Haertle, Natalia Buenache Cuenda, Isabel Espejo Diaz, Paula Lázaro Del Campo, Andres Arroyo-Barea, Leonie Rieger, Juan Manuel Rosa-Rosa, Rafael Alonso Fernandez, Nieves Lopez, José Sanchez-Pina, Almudena García-Ortiz, Antonio Valeri, Santiago Barrio, Fatima Al-Shahrour, Florian Bassermann, Joaquin Martínez-López, Tomas Di Domenico
Journal: Blood
Blood (2024) 144 (Supplement 1): 5794.
https://doi.org/10.1182/blood-2024-198117
Published: 2024
Journal Articles

Enhancing CAR-T Cell Therapy for Non-Hodgkin Lymphoma through Gut Microbiota and Butyrate

Roberto Garcia-Vicente, Alba Rodríguez García, Raquel Ancos-Pintado, Andrés Arroyo Barea, Adriana Ortega-Hernandez, Irene Bragado-Garcia, Eva Castellano, Alejandra Ortiz-Ruiz, Miguel Angel Navarro-Aguadero, Javier Modrego, Alejandra Leivas, José Sanchez-Pina, Rafael Alonso Fernandez, Maria Hernandez-Sanchez, Mariateresa Fulciniti, Cecilia Carpio, Pere Barba, Diego Carbonell, Mi Kwon, Mariana Bastos-Oreiro, Alejandro Martín García-Sancho, Ana Jiménez Ubieto, Antonio Valeri, Dulcenombre Gomez-Garre, Joaquín Martínez-Lopez, María Linares
Journal: Blood
Blood (2024) 144 (Supplement 1): 3414.
https://doi.org/10.1182/blood-2024-205005
Published: 2024
Journal Articles

Personalized Monitoring of Circulating Tumor DNA By a Specific Signature of Trackable Mutations after Chimeric Antigen Receptor t-Cell Therapy in Non-Hodgkin B Cell Lymphoma

Santiago Barrio, Carolina Martinez-Laperche, Alejandro Martín-Muñoz, Margarita Rodriguez, Laura Rufian, Ismael de la Iglesia, Paula Muñiz Sevilla, Sara Dorado, Ana K Ballesteros, Rebeca Bailen, María Poza, Maria Chicano, Almudena García-Ortiz, Francisco Diaz Crespo, Jose Maria Sanchez Pina, Enrique Revilla, Pilar Sarandeses, Antonio Valeri, Mi Kwon, Joaquin Martinez-Lopez, Ismael Buño Borde, Ana Jimenez Ubieto, Mariana Bastos-Oreiro
Journal: Blood
Blood (2023) 142 (Supplement 1): 6087.
https://doi.org/10.1182/blood-2023-187057
Published: 2023
Journal Articles

CD155 on Multiple Myeloma Cells Is Epigenetically Regulated, Reduce Patients Survival and Compromises the Action of Novel Immunotherapies

Laura Martinez-Verbo, Lorea Villanueva, Pere Llinàs-Arias, Carlos Antonio García-Prieto, David Piñeyro, Aina Oliver-Caldes, Almudena García-Ortiz, Antonio Valeri, Carlos Fernández de Larrea, Joaquin Martinez-Lopez, Gerardo Ferrer, Manel Esteller
Journal: Blood
Blood (2023) 142 (Supplement 1): 6567.
https://doi.org/10.1182/blood-2023-179313
Published: 2023
Journal Articles

Intracytoplasmatic BCMA Point Mutation and Teclistamab Resistance: Genomic Assessment of a Multidrug-Resistant Multiple Myeloma Patient

Natalia Buenache Cuenda, Hipolito Nicolas Cuesta Hernández, Alicia Giménez Sánchez, Laura Carneros Blanco, Juan Manuel Rosa-Rosa, Yanira Ruiz-Heredia, Enrique Revilla, Seungbin Han, Umair Munawar, Inmaculada Rapado, Rosa Ayala, K. Martin Kortüm, Antonio Valeri, Santiago Barrio, Joaquin Martinez Lopez, Larissa Haertle
Journal: Blood
Blood (2023) 142 (Supplement 1): 1925.
https://doi.org/10.1182/blood-2023-184824
Published: 2023
Journal Articles

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

Umair Munawar, Xiang Zhou, Sabrina Prommersberger, Max Johannes Steinhardt, Julia Mersi, Max Bittrich, Silvia Nerreter, Cornelia Vogt, Eva Teufel, Seungbin Han, Larissa Haertle, Patrick Eiring, Nicole Banholzer, Sophia Danhof, Adrián Fernández-Martín, Marietta Truger, Santiago Barrio, Miguel Gallardo, Antonio Valeri, Eva Castellano, Peter Raab, Claudia Haferlach, Markus Sauer, Michael Hudecek, Joaquin Martinez-Lopez, Hermann Einsele, Leo Rasche, Martin Kortuem
Journal: Blood
Blood (2022) 140 (Supplement 1): 4226–4227.
https://doi.org/10.1182/blood-2022-168702
Published: 2022
Journal Articles

NKG2D CAR-Expressing Lymphocytes Target Acute Myeloid Leukemia Cells

Alejandra Leivas, PhD BS, MSc, Laura Córdoba, MSc, Antonio Valeri, PhD, Paula Rio, PhD, Daniel Primo, PhD, Joan Ballesteros, PhD, Lucía Fernández, PhD, Antonio Perez-Martinez, MD PhD, Dean Anthony Lee, MD PhD, Daniel J. Powell, Jr., PhD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2667.
https://doi.org/10.1182/blood-2019-123371
Published: 2019
Journal Articles

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Alejandra Ortiz-Ruiz, BSc, Yanira Ruiz-Heredia, Mehmet Samur, PhD, Pedro Aguilar-Garrido, Maria Luz Morales, Antonio Valeri, PhD, Almudena Garcia-Ortiz, PhD, Santiago Barrio, PhD, Carmen Bárcena, Rosa Maria Garcia-Martin, Vanesa Garrido, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD, María Teresa Cedena, Joaquin Martinez-Lopez, MD PhD, Maria Linares, PhD, Miguel Gallardo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4408.
https://doi.org/10.1182/blood-2019-123950
Published: 2019
Journal Articles

NKG2D-CAR Transduced Primary Natural Killer Cells Efficiently Target Multiple Myeloma Cells

Alejandra Leivas, PhD BS, MSc, Paula Rio, PhD, Rebeca Mateos, MSc, Mari Liz Paciello, MD, Almudena Garcia-Ortiz, PhD, Lucia Fernandez, PhD, Antonio Perez-Martinez, MD PhD, Dean Anthony Lee, MD PhD, Daniel J. Powell, Jr., PhD, Antonio Valeri, PhD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 590.
https://doi.org/10.1182/blood-2018-99-114522
Published: 2018
Journal Articles

Activated and Expanded Natural Killer Cells Expressing an NKG2D-CAR Efficiently Target Multiple Myeloma Cells

Alejandra Leivas, PhD BS, MSc, Antonio Valeri, PhD, Paula Rio, PhD, Lucia Fernandez, PhD, Iñaki Pañero, Dean Anthony Lee, MD PhD, Daniel J. Powell, Jr., PhD, Juan Jose Lahuerta, Antonio Perez-Martinez, MD PhD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4466.
https://doi.org/10.1182/blood.V130.Suppl_1.4466.4466
Published: 2017
Journal Articles

Abnormalities in Mitochondrial DNA Copy Number Have Pathogenetic and Prognostic Implications in Multiple Myeloma

Yanira Ruiz-Heredia, Mehmet Kemal Samur, PhD, Alejandra Ortiz-Ruiz, Rafael Alonso Fernández, Beatriz Sanchez-Vega, Alberto Blazquez, Aitor Delmiro, Jose Carlos Martinez-Avila, Esther Onecha, Antonio Valeri, PhD, Miguel Angel Martin, Niccolo Bolli, MD, Yu-Tzu Tai, PhD, Francesco Maura, Raphael Szalat, MD, Mariateresa Fulciniti, PhD, María Linares, PhD, Miguel Gallardo, PhD, Peter J Campbell, MD PhD, Hervé Avet-Loiseau, Juan Jose Lahuerta, Nikhil Munshi, MD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4378.
https://doi.org/10.1182/blood.V130.Suppl_1.4378.4378
Published: 2017
Journal Articles

Maintenance Treatment with Lenalidomide for Multiple Myeloma Increases the Proportion of MRD Negative (Flow-/PET-CT-) Patients

Rafael Alonso Fernández, María Teresa Cedena, Rafael Rios, Javier Lopez Jimenez, Alejandro Sanz, Fernando Martín, Antonio Valeri, PhD, Juan Jose Lahuerta, Joaquin Martínez-López
Journal: Blood
Blood (2017) 130 (Supplement 1): 3098.
https://doi.org/10.1182/blood.V130.Suppl_1.3098.3098
Published: 2017
Journal Articles

Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to Bortezomib, Thalidomide and Dexamethasone (VTD) As Induction Therapy for the Treatment of Transplant Eligible Multiple Myeloma

Victor Jimenez-Zepeda, MD, Nizar J. Bahlis, MD, Peter Duggan, MD, Rafael Alonso, MD, Juan José Lahuerta, MD PhD, Antonio Valeri, Paola Neri, MD PhD, Jason Tay, MD FRCPC MSc, Joaquin Martinez-Lopez
Journal: Blood
Blood (2016) 128 (22): 4505.
https://doi.org/10.1182/blood.V128.22.4505.4505
Published: 2016
Journal Articles

Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma

Alejandra Gutiérrez-González, Mónica Martínez-Moreno, Rafael Samaniego, Noemí Arellano-Sánchez, Laura Salinas-Muñoz, Miguel Relloso, Antonio Valeri, Joaquín Martínez-López, Ángel L. Corbí, Andrés Hidalgo, Ángeles García-Pardo, Joaquín Teixidó, Paloma Sánchez-Mateos
Journal: Blood
Blood (2016) 128 (18): 2241–2252.
https://doi.org/10.1182/blood-2016-01-695395
Published: 2016
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