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Journal Articles

Mutation-Specific Differences in the Relationship between Obesity and Clonal Hematopoiesis, with a Focus on JAK2 V617F and MPN Prevention

Blood (2024) 144 (Supplement 1): 872.

https://doi.org/10.1182/blood-2024-204211

Published: 2024

Journal Articles

Epigenetic Modifications As a Mechanism of Resistance to BCMA-Directed Immunotherapies in Multiple Myeloma: Insights from Multi-Omic Profiling

Larissa Haertle, Natalia Buenache Cuenda, Isabel Espejo Diaz, Paula Lázaro Del Campo, Andres Arroyo-Barea, Leonie Rieger, Juan Manuel Rosa-Rosa, Rafael Alonso Fernandez, Nieves Lopez, José Sanchez-Pina, Almudena García-Ortiz, Antonio Valeri, Santiago Barrio, Fatima Al-Shahrour, Florian Bassermann, Joaquin Martínez-López, Tomas Di Domenico

Blood (2024) 144 (Supplement 1): 5794.

https://doi.org/10.1182/blood-2024-198117

Published: 2024

Journal Articles

Whole-genome CRISPR screening identifies N- glycosylation as a genetic and therapeutic vulnerability in CALR -mutant MPNs

Jonas S. Jutzi, Anna E. Marneth, Michele Ciboddo, Angel Guerra-Moreno, María José Jiménez-Santos, Anastasia Kosmidou, James W. Dressman, Hongyan Liang, Rebecca Hamel, Patricia Lozano, Elisa Rumi, John G. Doench, Jason Gotlib, Anandi Krishnan, Shannon Elf, Fátima Al-Shahrour, Ann Mullally

Blood (2022) 140 (11): 1291–1304.

https://doi.org/10.1182/blood.2022015629

Published: 2022

Includes: Supplemental data

Journal Articles

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Larisa V. Kovtonyuk, Francisco Caiado, Santiago Garcia-Martin, Eva-Maria Manz, Patrick Helbling, Hitoshi Takizawa, Steffen Boettcher, Fatima Al-Shahrour, Cesar Nombela-Arrieta, Emma Slack, Markus G. Manz

Blood (2022) 139 (1): 44–58.

https://doi.org/10.1182/blood.2021011570

Published: 2022

Includes: Supplemental data

Journal Articles

Whole-Genome CRISPR Screening Identifies N -Glycosylation As an Essential Pathway and a Potential Novel Therapeutic Target in CALR -Mutant MPN

Anna E. Marneth, Jonas S. Jutzi, Angel Guerra-Moreno, Michele Ciboddo, María José Jiménez Santos, Anastasia Kosmidou, Rebecca Hamel, Patricia Lozano, Elisa Rumi, John G. Doench, Jason Gotlib, Anandi Krishnan, Shannon Elf, Fatima Al-Shahrour, Ann Mullally

Blood (2021) 138 (Supplement 1): 58.

https://doi.org/10.1182/blood-2021-149218

Published: 2021

Journal Articles

RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program

Blood (2016) 128 (22): 739.

https://doi.org/10.1182/blood.V128.22.739.739

Published: 2016

Journal Articles

Physical Interaction Between Mutant Calreticulin and the Thrombopoietin Receptor Is Required for Hematopoietic Transformation

Shannon Elf, PhD, Nouran Abdelfattah, MPhil, Edwin Chen, PhD, Javier Perales-Patón, Emily Rosen, BS, Amy Ko, Fabian Peisker, Natalie Florescu, Silvia Giannini, PhD, Ofir Wolach, MD, Elizabeth A. Morgan, MD, Julie-Aurore Losman, MD, PhD, Rebekka K. Schneider, MD, Fatima Al-Shahrour, PhD, Ann Mullally, MD

Blood (2015) 126 (23): LBA-4.

https://doi.org/10.1182/blood.V126.23.LBA-4.LBA-4

Published: 2015

Journal Articles

Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

Raajit Rampal, Fatima Al-Shahrour, Omar Abdel-Wahab, Jay P. Patel, Jean-Philippe Brunel, Craig H. Mermel, Adam J. Bass, Jennifer Pretz, Jihae Ahn, Todd Hricik, Outi Kilpivaara, Martha Wadleigh, Lambert Busque, D. Gary Gilliland, Todd R. Golub, Benjamin L. Ebert, Ross L. Levine

Blood (2014) 123 (22): e123–e133.

https://doi.org/10.1182/blood-2014-02-554634

Published: 2014

Includes: Supplemental data

Journal Articles

Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells

Sun-Mi Park, Ph.D, Raquel P Deering, Yuheng Lu, Tivnan Patrick, Varun Shenoy, Steve Lianoglou, Ph.D, Fatima Al-Shahrour, Christina Leslie, Benjamin L. Ebert, MD, PhD, Christopher Lengner, George Q Daley, Michael G Kharas, PhD

Blood (2013) 122 (21): 468.

https://doi.org/10.1182/blood.V122.21.468.468

Published: 2013

Journal Articles

Casein Kinase 1 Alpha Maintains Normal and Leukemic Stem Cells by Regulating p53 Activity

Marcus Järås, PhD, Peter G. Miller, PhD, Lisa Chu, Rebekka K. Schneider, MD, Rishi V Puram, Fatima Al-Shahrour, PhD, Emma Fink, Kimberly A. Hartwell, PhD, Marie McConkey, Glenn Cowley, PhD, Ann Mullally, MD, Michael G Kharas, PhD, Benjamin L. Ebert

Blood (2012) 120 (21): 209.

https://doi.org/10.1182/blood.V120.21.209.209

Published: 2012

Journal Articles

Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate.

Sun Mi Park, Ph.D, Raquel Deering, Yuheng Lu, Patrick Tivnan, Varun Shenoy, Steve Lianoglou, Ph.D, Fatima Al-Shahrour, PhD, Christina Leslie, PhD, Benjamin L. Ebert, MD, PhD, Christopher Lengner, Ph.D, George Q. Daley, MD, PhD, Michael G Kharas, PhD

Blood (2012) 120 (21): 2324.

https://doi.org/10.1182/blood.V120.21.2324.2324

Published: 2012

Journal Articles

Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera

Ann Mullally, Luke Poveromo, Rebekka K. Schneider, Fatima Al-Shahrour, Steven W. Lane, Benjamin L. Ebert

Blood (2012) 120 (1): 166–172.

https://doi.org/10.1182/blood-2012-01-402396

Published: 2012

Includes: Supplemental data

Journal Articles

Msi2 Maintains Normal Hematopoietic Stem Cell Self-Renewal

Michael G Kharas, PhD, Christopher Lengner, Ph.D, Fatima Al-Shahrour, PhD, Benjamin L. Ebert, MD, D.Phil, George Q. Daley, MD, PhD

Blood (2011) 118 (21): 222.

https://doi.org/10.1182/blood.V118.21.222.222

Published: 2011

Journal Articles

In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling

Blood (2011) 118 (21): 758.

https://doi.org/10.1182/blood.V118.21.758.758

Published: 2011

Journal Articles

Evaluating Clonal Dominance in a Murine Knock-in Model of Jak2V617F MPN

Ann Mullally, MD, Luke Poveromo, Kristina Brumme, Fatima Al-Shahrour, PhD, Steven W. Lane, Alan H. Shih, MD, PhD, Iannis Aifantis, PhD, Ross L Levine, MD, Benjamin L. Ebert, MD, D.Phil

Blood (2011) 118 (21): 614.

https://doi.org/10.1182/blood.V118.21.614.614

Published: 2011

Journal Articles

Dexamethasone and lenalidomide have distinct functional effects on erythropoiesis

Anupama Narla, Shilpee Dutt, J. Randall McAuley, Fatima Al-Shahrour, Slater Hurst, Marie McConkey, Donna Neuberg, Benjamin L. Ebert

Blood (2011) 118 (8): 2296–2304.

https://doi.org/10.1182/blood-2010-11-318543

Published: 2011

Includes: Supplemental data

Journal Articles

Characterizing the Disease-Initiating Cell Population In a Murine Model of Jak2V617F+ Myeloproliferative Neoplasm

Ann Mullally, MD, Steven W. Lane, MD, Luke Poveromo, Fatima Al-Shahrour, Jeffery Kutok, MD, PhD, Benjamin L. Ebert, MD, DPhil

Blood (2010) 116 (21): 317.

https://doi.org/10.1182/blood.V116.21.317.317

Published: 2010

Journal Articles

The Apc min mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

Steven W. Lane, Stephen M. Sykes, Fatima Al-Shahrour, Sebastian Shterental, Mahnaz Paktinat, Cristina Lo Celso, Jonathan L. Jesneck, Benjamin L. Ebert, David A. Williams, D. Gary Gilliland

Blood (2010) 115 (17): 3489–3497.

https://doi.org/10.1182/blood-2009-11-251728

Published: 2010

Includes: Supplemental data

Journal Articles

Niche Induced Myelodysplasia and Secondary Hematopoietic Neoplasia Caused by Deletion of Dicer1 in Osteoprogenitor Cells.

Marc HGP Raaijmakers, MD, PhD, Siddhartha Mukherjee, M.D., Shangqin Guo, PhD, Tatsuya Kobayashi, PhD, Jesse Schoonmaker, Zinmar Aung, Benjamin L. Ebert, MD, DPhil, Fatima Al-Shahrour, Robert P Hasserjian, MD, Sonia Vallet, MD, Edward Scadden, Charles P Lin, David T. Scadden, MD

Blood (2009) 114 (22): 247.

https://doi.org/10.1182/blood.V114.22.247.247

Published: 2009

Journal Articles

Transcriptome Classification of B-Cell Non-Hodgkins Lymphoma.

Mohit Aggarwal, MD, Raquel Villuendas, Ph.D., Fatima Al-Shahrour, Ph.D., Abel S. Aguilera, Ph.D., Nerea Martinez, Ph.D., Elena R. Ballesteros, B.Sc, Francisca I. Camacho, MD, Ph.D, Alberto Perez, Ph.D, Maria J. Artiga, Ph.D., Jose A. Garcia-Marco, M.D, PhD, Joaquin Dopazo, Ph.D, Miguel A. Piris, MD, PhD

Blood (2006) 108 (11): 819.

https://doi.org/10.1182/blood.V108.11.819.819

Published: 2006

NARROW

Mutation-Specific Differences in the Relationship between Obesity and Clonal Hematopoiesis, with a Focus on JAK2 V617F and MPN Prevention

Epigenetic Modifications As a Mechanism of Resistance to BCMA-Directed Immunotherapies in Multiple Myeloma: Insights from Multi-Omic Profiling

Whole-genome CRISPR screening identifies N- glycosylation as a genetic and therapeutic vulnerability in CALR -mutant MPNs

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Whole-Genome CRISPR Screening Identifies N -Glycosylation As an Essential Pathway and a Potential Novel Therapeutic Target in CALR -Mutant MPN

RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program

Physical Interaction Between Mutant Calreticulin and the Thrombopoietin Receptor Is Required for Hematopoietic Transformation

Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells

Casein Kinase 1 Alpha Maintains Normal and Leukemic Stem Cells by Regulating p53 Activity

Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate.

Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera

Msi2 Maintains Normal Hematopoietic Stem Cell Self-Renewal

In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling

Evaluating Clonal Dominance in a Murine Knock-in Model of Jak2V617F MPN

Dexamethasone and lenalidomide have distinct functional effects on erythropoiesis

Characterizing the Disease-Initiating Cell Population In a Murine Model of Jak2V617F+ Myeloproliferative Neoplasm

The Apc min mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

Niche Induced Myelodysplasia and Secondary Hematopoietic Neoplasia Caused by Deletion of Dicer1 in Osteoprogenitor Cells.

Transcriptome Classification of B-Cell Non-Hodgkins Lymphoma.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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