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Journal Articles

Low CD117 Expression Identifies Hematopoietic Stem Cell Subsets with Enhanced Lymphoid Potential in Mice and Humans

Harold K Elias, Sneha Mitra, Brianna Gipson, Marina Burgos da Silva, Nicole Lee, Mohamed A.E. Ali, Simon Grassman, Anastasia Kousa, Susan DeWolf, Christopher Y. Park, Joseph Sun, Christina Leslie, Avinash Bhandoola, Marcel R.M. van den Brink

Blood (2023) 142 (Supplement 1): 3417.

https://doi.org/10.1182/blood-2023-190000

Published: 2023

Journal Articles

RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality

Florisela Herrejon Chavez, Paolo Cifani, Alli Pine, Karen L Chu, Ersilia Barin, Alexandra Schurer, Hanzhi Luo, Diu T.T. Nguyen, Alex Kentsis, Christina Leslie, Michael G Kharas, Ly P Vu

Blood (2021) 138 (Supplement 1): 296.

https://doi.org/10.1182/blood-2021-147575

Published: 2021

Journal Articles

Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia

Diu T.T. Nguyen, DPhil, Camila Prieto, PhD, Zhaoqi Liu, PhD, Justin Wheat, Alexendar Perez, Saroj Gourkanti, BA, Timothy Chou, BS, Ersilia Barin, Arthur Chow, BS, James Taggart, BA, Katerina Hoskova, Meera Dhodapkar, Alexandra Schurer, BS, Trevor Stephen Barlowe, BA, Ly Vu, PhD, Christina Leslie, PhD, Ulrich G. Steidl, MDPhD, Raul Rabadan, PhD, Michael G. Kharas, PhD

Blood (2020) 136 (Supplement 1): 15.

https://doi.org/10.1182/blood-2020-142229

Published: 2020

Journal Articles

Targeted Integration of a CAR at a Novel Genomic Safe Harbor Directs Potent Therapeutic Outcomes

Ashlesha Odak, MS, Han Yuan, PhD, Judith Feucht, MD, Jorge Mansilla - Soto, PhD, Justin Eyquem, PhD, Christina Leslie, PhD, Michel Sadelain, MD PhD

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-141967

Published: 2020

Journal Articles

Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 428.

https://doi.org/10.1182/blood-2018-99-118745

Published: 2018

Journal Articles

RNA Binding Protein Rbmx Is Required in Acute Myeloid Leukemia By Regulating the Transcriptional Activity of the Heterochromatin Protein HP1α

Camila Prieto, BA, Diu Nguyen, PhD, Ly P Vu, PhD, Alexendar Perez, PhD, Saroj Gourkanti, BA, Alexandra Schurer, BS, Timothy Chou, BS, Arthur Chow, BA, James Taggart, BA, Trevor Stephen Barlowe, BA, Christina Leslie, PhD, Michael G. Kharas, PhD

Blood (2018) 132 (Supplement 1): 883.

https://doi.org/10.1182/blood-2018-99-112543

Published: 2018

Journal Articles

The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells

Diu Nguyen, PhD, Yuheng Lu, PhD, Zi-ning Choo, Christopher Chin, Camila Prieto, BA, Saroj Gourkanti, BA, Christina Leslie, PhD, Michael G. Kharas, PhD

Blood (2018) 132 (Supplement 1): 884.

https://doi.org/10.1182/blood-2018-99-118949

Published: 2018

Journal Articles

IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells

Sun-Mi Park, PhD, Hyunwoo Cho, PhD, Angela Thornton, PhD, Trevor Stephen Barlowe, BA, Timothy Chou, BS, Sagar Chhangawala, PhD, Lauren Fairchild, PhD, Arthur Chow, BA, James Taggart, BA, Alexander Schurer, BA, Antoine Gruet, Matthew Witkin, Jun Hyun Kim, Ethan Shevach, Andrei Krivstov, Scott A. Armstrong, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD

Blood (2018) 132 (Supplement 1): 3881.

https://doi.org/10.1182/blood-2018-99-115034

Published: 2018

Journal Articles

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

Josephine Wesely, PhD MSc, BSc, Andriana G. Kotini, PhD, Maria Georgomanoli, PhD, Hanzhi Luo, PhD, Han Yuan, Franco Izzo, PhD, Dan A. Landau, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 772.

https://doi.org/10.1182/blood-2018-99-111506

Published: 2018

Journal Articles

RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program

Blood (2016) 128 (22): 739.

https://doi.org/10.1182/blood.V128.22.739.739

Published: 2016

Journal Articles

Microrna Mediated Regulation of Hematopoietic Stem Cell Aging

Safak Yalcin, PhD, Mark Carty, Joseph Yusup Shin, Richard A Miller, PhD, Christina Leslie, PhD, Christopher Y. Park, MD PhD

Blood (2014) 124 (21): 602.

https://doi.org/10.1182/blood.V124.21.602.602

Published: 2014

Journal Articles

Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program

Sun Mi Park, PhD, Mithat Gönen, PhD, Ly P. Vu, PhD, Gerard Minuesa, PhD, Patrick Tivnan, Trevor Barlowe, James Taggart, Yuheng Lu, Raquel P Deering, PhD, Nir Hacohen, PhD, Maria Figueroa, MD, Elisabeth M. Paietta, PhD, Martin S. Tallman, MD, Ari M. Melnick, MD, Ross L. Levine, MD, Christina Leslie, PhD, Christopher J Lengner, PhD, Michael G Kharas, PhD

Blood (2014) 124 (21): 836.

https://doi.org/10.1182/blood.V124.21.836.836

Published: 2014

Journal Articles

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

Barbara Spitzer, MD, Olga A Guryanova, MD PhD, Omar Abdel-Wahab, MD, Nicole Kucine, MD, Mazhar Adli, PhD, Jason N. Berman, MD, Soheil Meshinchi, MD PhD, Bradley Bernstein, MD PhD, Raphael Pelossof, PhD, Christina Leslie, PhD, Ross L. Levine, MD

Blood (2014) 124 (21): 2186.

https://doi.org/10.1182/blood.V124.21.2186.2186

Published: 2014

Journal Articles

A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL

Richard R. Furman, MD, Shuhua Cheng, PhD, Pin Lu, MD, PhD, Menu Setty, Alexandar Perez, Ailin Guo, MD, PhD, Joelle Racchumi, BS, Jiao Ma, PhD, Morton Coleman, MD, Kabaleeswaran Venkataraman, PhD, Guozhou Xu, PhD, Wei Chen, PhD, Hao Wu, PhD, Betty Y. Chang, PhD, Christina Leslie, PhD, Y. Lynn Wang, MD, PhD

Blood (2013) 122 (21): 4914.

https://doi.org/10.1182/blood.V122.21.4914.4914

Published: 2013

Journal Articles

Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells

Sun-Mi Park, Ph.D, Raquel P Deering, Yuheng Lu, Tivnan Patrick, Varun Shenoy, Steve Lianoglou, Ph.D, Fatima Al-Shahrour, Christina Leslie, Benjamin L. Ebert, MD, PhD, Christopher Lengner, George Q Daley, Michael G Kharas, PhD

Blood (2013) 122 (21): 468.

https://doi.org/10.1182/blood.V122.21.468.468

Published: 2013

Journal Articles

Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate.

Sun Mi Park, Ph.D, Raquel Deering, Yuheng Lu, Patrick Tivnan, Varun Shenoy, Steve Lianoglou, Ph.D, Fatima Al-Shahrour, PhD, Christina Leslie, PhD, Benjamin L. Ebert, MD, PhD, Christopher Lengner, Ph.D, George Q. Daley, MD, PhD, Michael G Kharas, PhD

Blood (2012) 120 (21): 2324.

https://doi.org/10.1182/blood.V120.21.2324.2324

Published: 2012

Journal Articles

MiR-28 Silencing In Germinal Center-Derived Lymphomas

Christof Schneider, MD, Roy L Maute, Pavel Sumazin, PhD, Manisha Brahmachary, PhD, Manu Setty, Laura Pasqualucci, MD, Angelo Rosolen, MD, Christina Leslie, PhD, Katia Basso, PhD, Riccardo Dalla-Favera, MD

Blood (2010) 116 (21): 703.

https://doi.org/10.1182/blood.V116.21.703.703

Published: 2010

Journal Articles

Therapeutic Transgene Expression From Genomic Safe Harbors In Patient-Specific Induced Pluripotent Stem Cells

Eirini P Papapetrou, MD, PhD, Gabsang Lee, PhD, Nirav Malani, Manu Setty, Isabelle Riviere, PhD, Laxmi MS Tirunagari, Kyuichi Kadota, MD, Shoshannah L Roth, PhD, Patricia Giardina, MD, Agnes Viale, PhD, Christina Leslie, PhD, Frederic Bushman, PhD, Lorenz Studer, MD, Michel Sadelain, MD, PhD

Blood (2010) 116 (21): 564.

https://doi.org/10.1182/blood.V116.21.564.564

Published: 2010

NARROW

Low CD117 Expression Identifies Hematopoietic Stem Cell Subsets with Enhanced Lymphoid Potential in Mice and Humans

RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality

Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia

Targeted Integration of a CAR at a Novel Genomic Safe Harbor Directs Potent Therapeutic Outcomes

Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia

RNA Binding Protein Rbmx Is Required in Acute Myeloid Leukemia By Regulating the Transcriptional Activity of the Heterochromatin Protein HP1α

The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells

IKZF2 Drives Self-Renewal and Blocks Myeloid Differentiation Programs in Myeloid Leukemic Stem Cells

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program

Microrna Mediated Regulation of Hematopoietic Stem Cell Aging

Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL

Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells

Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate.

MiR-28 Silencing In Germinal Center-Derived Lymphomas

Therapeutic Transgene Expression From Genomic Safe Harbors In Patient-Specific Induced Pluripotent Stem Cells

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American Society of Hematology

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American Society of Hematology

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