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Journal Articles

Uncovering the HOXA9 Translational Regulatory Complex That Promotes AML Leukemic Stem Cells

Xueqin Xie, Florisela Herrejon Chavez, Ilyes Baali, Eren L. Chu, Chiara Evans, Xuejing Yang, Wei Wei, Hanzhi Luo, Sun Mi Park, Kathryn Chang, Aspen Pierson, Grace Han, Emily Batchelor, Quaid D. Morris, Ly Vu, Diu T.T. Nguyen, Michael G. Kharas
Journal: Blood
Blood (2024) 144 (Supplement 1): 4106.
https://doi.org/10.1182/blood-2024-211477
Published: 2024
Journal Articles

Rbmx Regulates YTHDC1 Nuclear Condensates to Promote Nascent Transcription in Acute Myeloid Leukemia

Isaac Wakiro, Yue Huang, Xuejing Yang, Xueqin Xie, Hanzhi Luo, Kathryn Chang, Aspen Pierson, Emily Batchelor, Yuanming Cheng, Diu T.T. Nguyen, Zhaoqi Liu, Michael G. Kharas
Journal: Blood
Blood (2024) 144 (Supplement 1): 627.
https://doi.org/10.1182/blood-2024-211338
Published: 2024
Journal Articles

A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML

Tao Dao, Guangyan Xiong, Sung Soo Mun, Jeremy Meyerberg, Tatyana Korontsvit, Jingyi Xiang, Ziyou Cui, Aaron Y. Chang, Casey Jarvis, Winson Cai, Hanzhi Luo, Aspen Pierson, Anthony Daniyan, Sarah Yoo, Sumiko Takao, Michael Kharas, Alex Kentsis, Cheng Liu, David A. Scheinberg
Journal: Blood
Blood (2024) 143 (6): 507–521.
https://doi.org/10.1182/blood.2023021054
Published: 2024
Includes: Supplemental data
Journal Articles

m 6 a-Son-CCL5 Axis Controls HSC Fate and Inflammation

Hanzhi Luo, Mariela Cortés-López, Cyrus L. Tam, Michael Xiao, Isaac Wakiro, Karen L. Chu, Aspen Pierson, Mandy Chan, Kathryn Chang, Xuejing Yang, Grace Han, Erin Ahn, Quaid D. Morris, Dan A. Landau, Michael G. Kharas
Journal: Blood
Blood (2023) 142 (Supplement 1): 1297.
https://doi.org/10.1182/blood-2023-179552
Published: 2023
Journal Articles

Fructose Treatment Targets Myeloid Leukemogenesis in IDH2 Mutants By Exhausting Alpha-Ketoglutarate Pools

Angela Maria Savino, Briana Turner, Sangmoo Jeong, Tanya Schild, Xuejing Yang, Hanzhi Luo, Rachel Chirayil, Quinlan Cullen, Mandy Chan, Grace Han, Kathryn Chang, Sudha Janaki Raman, Justin R Cross, Kayvan Keshari, Michael G Kharas
Journal: Blood
Blood (2022) 140 (Supplement 1): 2966–2967.
https://doi.org/10.1182/blood-2022-164626
Published: 2022
Journal Articles

Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia

Nataly Cruz-Rodriguez, Andriana G. Kotini, Saul Carcamo, Malgorzata Olszewska, Elsa Bernard, Hanzhi Luo, Michael G Kharas, Dan Hasson, Eirini P. Papapetrou
Journal: Blood
Blood (2022) 140 (Supplement 1): 1996–1997.
https://doi.org/10.1182/blood-2022-165728
Published: 2022
Journal Articles

A TCR mimic CAR T cell specific for NDC80 is broadly reactive with solid tumors and hematologic malignancies

Martin G. Klatt, Tao Dao, Zhiyuan Yang, Jianying Liu, Sung Soo Mun, Megan M. Dacek, Hanzhi Luo, Thomas J. Gardner, Christopher Bourne, Leila Peraro, Zita E. H. Aretz, Tanya Korontsvit, Michael Lau, Michael G. Kharas, Cheng Liu, David A. Scheinberg
Journal: Blood
Blood (2022) 140 (8): 861–874.
https://doi.org/10.1182/blood.2021012882
Published: 2022
Includes: Supplemental data
Journal Articles

RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality

Florisela Herrejon Chavez, Paolo Cifani, Alli Pine, Karen L Chu, Ersilia Barin, Alexandra Schurer, Hanzhi Luo, Diu T.T. Nguyen, Alex Kentsis, Christina Leslie, Michael G Kharas, Ly P Vu
Journal: Blood
Blood (2021) 138 (Supplement 1): 296.
https://doi.org/10.1182/blood-2021-147575
Published: 2021
Journal Articles

m 6 A Maintains Hematopoietic Stem and Progenitor Cell Identity

Yuanming Cheng, PhD, Hanzhi Luo, PhD, Franco Izzo, PhD, Brian F Pickering, PhD, Ly P Vu, PhD, Alexandra Schurer, BS, Saroj Gourkanti, BA, Samie R. Jaffrey, MD PhD, Dan A. Landau, MD PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 327.
https://doi.org/10.1182/blood-2018-99-117191
Published: 2018
Journal Articles

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

Josephine Wesely, PhD MSc, BSc, Andriana G. Kotini, PhD, Maria Georgomanoli, PhD, Hanzhi Luo, PhD, Han Yuan, Franco Izzo, PhD, Dan A. Landau, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD, Eirini P. Papapetrou, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 772.
https://doi.org/10.1182/blood-2018-99-111506
Published: 2018