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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Blood (2024) 144 (23): 2402–2416.

https://doi.org/10.1182/blood.2024025023

Published: 2024

Includes: Supplemental data

Journal Articles

Hematopoietic and eosinophil-specific LNK(SH2B3) deficiency promotes eosinophilia and arterial thrombosis

Huijuan Dou, Ranran Wang, Mojdeh Tavallaie, Tong Xiao, Malgorzata Olszewska, Eirini P. Papapetrou, Alan R. Tall, Nan Wang

Blood (2024) 143 (17): 1758–1772.

https://doi.org/10.1182/blood.2023021055

Published: 2024

Includes: Supplemental data

Journal Articles

Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia

Nataly Cruz-Rodriguez, Andriana G. Kotini, Saul Carcamo, Malgorzata Olszewska, Elsa Bernard, Hanzhi Luo, Michael G Kharas, Dan Hasson, Eirini P. Papapetrou

Blood (2022) 140 (Supplement 1): 1996–1997.

https://doi.org/10.1182/blood-2022-165728

Published: 2022

Journal Articles

MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia

Pedro Henrique Alves da Silva, Samantha Xing, Andriana G. Kotini, Eirini P. Papapetrou, Xiaoyu Song, Kai W. Wucherpfennig, John Mascarenhas, Lucas Ferrari de Andrade

Blood (2022) 139 (2): 205–216.

https://doi.org/10.1182/blood.2021011619

Published: 2022

Includes: Supplemental data

Journal Articles

Isogenic MDS-RS Patient-Derived iPSCs Define the Mis-Spliced Transcript Repertoire and Chromatin Landscape of SF3B1-Mutant Hematopoietic Stem/Progenitor Cells

George Asimomitis, André G. Deslauriers, Andriana G. Kotini, Elsa Bernard, Davide Esposito, Malgorzata Olszewska, Nikolaos Spyrou, Juan Arango Ossa, Teresa Mortera-Blanco, Richard Koche, Stuart Aaronson, Eva Hellström-Lindberg, Elli Papaemmanuil, Eirini P. Papapetrou

Blood (2021) 138 (Supplement 1): 147.

https://doi.org/10.1182/blood-2021-149830

Published: 2021

Journal Articles

The SF3B1 K700E Mutation Induces R-Loop Accumulation and Associated DNA Damage

Blood (2019) 134 (Supplement_1): 4219.

https://doi.org/10.1182/blood-2019-126981

Published: 2019

Journal Articles

Synthetic Lethality CRISPR Screens in Isogenic iPSCs with Splicing Factor Gene Mutations

Henrik Sperber, PhD, Shailee Vora, BS, MS, Andriana G. Kotini, PhD, Malgorzata Olszewska, MS, Aleksandra Wroblewska, PhD, Brian Brown, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 3083.

https://doi.org/10.1182/blood-2018-99-111857

Published: 2018

Journal Articles

Induced Pluripotent Stem Cells to Model Blood Diseases

Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): SCI-15.

https://doi.org/10.1182/blood-2018-99-109425

Published: 2018

Journal Articles

Modeling Calreticulin-Mutant Myeloproliferative Neoplasms with Isogenic Induced Pluripotent Stem Cells

Wei Wang, PhD, Tiansu Wang, PhD, Andriana G. Kotini, PhD, Camelia Iancu-Rubin, PhD, Ronald Hoffman, MD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 4319.

https://doi.org/10.1182/blood-2018-99-111512

Published: 2018

Journal Articles

Functional Analysis of MYC Deregulation By Diverse Genetic Mechanisms during Hematopoiesis

Nicole Stokes, BA, David Dominguez-Sola, MD PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 1323.

https://doi.org/10.1182/blood-2018-99-110829

Published: 2018

Journal Articles

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

Josephine Wesely, PhD MSc, BSc, Andriana G. Kotini, PhD, Maria Georgomanoli, PhD, Hanzhi Luo, PhD, Han Yuan, Franco Izzo, PhD, Dan A. Landau, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 772.

https://doi.org/10.1182/blood-2018-99-111506

Published: 2018

Journal Articles

A " De Novo Leukemogenesis" iPSC Model Charts the Clonal Evolution of Acute Myeloid Leukemia

Tiansu Wang, PhD, Andriana G. Kotini, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 773.

https://doi.org/10.1182/blood-2018-99-111613

Published: 2018

Journal Articles

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Melisa Ruiz-Gutierrez, MD PhD, Cailin Joyce, PhD, Ozge Vargel Bolukbasi, PhD, Andriana Kotini, PhD, Gabriela Alexe, Jennifer Whangbo, MD PhD, David Russell, MDPhD, Kimberly Stegmaier, MD, Carl D. Novina, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD

Blood (2017) 130 (Supplement 1): 875.

https://doi.org/10.1182/blood.V130.Suppl_1.875.875

Published: 2017

Journal Articles

Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells

Melisa Ruiz-Gutierrez, MD PhD, Ozge Vargel Bolukbasi, PhD, Linda Vo, Ryohichi Sugimura, MD PhD, Marilyn Sanchez Bonilla, MS, Andriana Kotini, PhD, Carl D. Novina, MD PhD, George Q. Daley, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD PhD

Blood (2016) 128 (22): 1496.

https://doi.org/10.1182/blood.V128.22.1496.1496

Published: 2016

Journal Articles

Isogenic iPSC Models of SRSF2 -Mutant Myelodysplastic Syndrome Capture Disease Phenotypes, Splicing Defects and Drug Responses

Chan-Jung Chang, PhD, Andriana Kotini, PhD, Julie Teruya-Feldstein, MD, Omar Abdel-Wahab, MD, Robert Bradley, PhD, Eirini P. Papapetrou, MD PhD

Blood (2016) 128 (22): 962.

https://doi.org/10.1182/blood.V128.22.962.962

Published: 2016

Journal Articles

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

Andriana Kotini, PhD, Jeffrey J Delrow, PhD, Timothy A. Graubert, MD, Stephen Nimer, MD, Eirini P Papapetrou, MD PhD

Blood (2014) 124 (21): 524.

https://doi.org/10.1182/blood.V124.21.524.524

Published: 2014

Journal Articles

An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery

Ibrahim Boussaad, PhD, Andriana Kotini, PhD, Emily K Dolezal, Stephen Nimer, MD, Eirini P Papapetrou, MD, PhD

Blood (2013) 122 (21): 859.

https://doi.org/10.1182/blood.V122.21.859.859

Published: 2013

Journal Articles

Chromosome 7q Hemizygosity Recapitulates MDS-Related Cellular Phenotypes In Genetically Engineered Human Pluripotent Stem Cells

Andriana Kotini, PhD, Ibrahim Boussaad, PhD, Eirini P Papapetrou, MD, PhD

Blood (2013) 122 (21): 862.

https://doi.org/10.1182/blood.V122.21.862.862

Published: 2013

Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD

Blood (2012) 120 (21): 2296.

https://doi.org/10.1182/blood.V120.21.2296.2296

Published: 2012

Journal Articles

IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment

Ibrahim Boussaad, PhD, Emily K Dolezal, Fabiana Perna, MD, Stephen D Nimer, MD, Eirini P Papapetrou, MD, PhD

Blood (2012) 120 (21): 174.

https://doi.org/10.1182/blood.V120.21.174.174

Published: 2012

NARROW

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Hematopoietic and eosinophil-specific LNK(SH2B3) deficiency promotes eosinophilia and arterial thrombosis

Patient-Derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia

MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia

Isogenic MDS-RS Patient-Derived iPSCs Define the Mis-Spliced Transcript Repertoire and Chromatin Landscape of SF3B1-Mutant Hematopoietic Stem/Progenitor Cells

The SF3B1 K700E Mutation Induces R-Loop Accumulation and Associated DNA Damage

Synthetic Lethality CRISPR Screens in Isogenic iPSCs with Splicing Factor Gene Mutations

Induced Pluripotent Stem Cells to Model Blood Diseases

Modeling Calreticulin-Mutant Myeloproliferative Neoplasms with Isogenic Induced Pluripotent Stem Cells

Functional Analysis of MYC Deregulation By Diverse Genetic Mechanisms during Hematopoiesis

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

A " De Novo Leukemogenesis" iPSC Model Charts the Clonal Evolution of Acute Myeloid Leukemia

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells

Isogenic iPSC Models of SRSF2 -Mutant Myelodysplastic Syndrome Capture Disease Phenotypes, Splicing Defects and Drug Responses

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery

Chromosome 7q Hemizygosity Recapitulates MDS-Related Cellular Phenotypes In Genetically Engineered Human Pluripotent Stem Cells

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment

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American Society of Hematology

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American Society of Hematology

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