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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Blood (2024) 144 (23): 2402–2416.

https://doi.org/10.1182/blood.2024025023

Published: 2024

Includes: Supplemental data

Journal Articles

A Single-Cell T-Cell Reference Map Delineates the Biological Landscape of CD4 + T Cells in Myelodysplastic Syndromes Under Venetoclax Therapy

Juan Jose Rodriguez Sevilla, Yang Liu, Irene Ganan-Gomez, Vera Adema, Kelly S. Chien, Guillermo Montalban-Bravo, Natthakan Thongon, Guillermo Garcia-Manero, Rashmi Kanagal-Shamanna, Sanam Loghavi, Hui Yang, Linghua Wang, Simona Colla

Blood (2024) 144 (Supplement 1): 50.

https://doi.org/10.1182/blood-2024-202641

Published: 2024

Journal Articles

Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms

Blood (2024) 144 (Supplement 1): 1816.

https://doi.org/10.1182/blood-2024-212052

Published: 2024

Journal Articles

T Lymphopenia and Aged Immune System Characterize Immunodeficiency in Adult Patients with Telomere Biology Disorders

Luiz Fernando Bazzo Catto, Nidhi Aggarwal, Ruba Shalhoub, Natthakan Thongon, Tania Rene Machado, Ivana Darden, Jennifer Lotter, Bhavisha A. Patel, Geraldine Aubert, Colin O. Wu, Simona Colla, Cynthia E. Dunbar, Fernanda Rodrigues, Emma M. Groarke

Blood (2024) 144 (Supplement 1): 4094.

https://doi.org/10.1182/blood-2024-207500

Published: 2024

Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Blood (2024) 144 (Supplement 1): 346.

https://doi.org/10.1182/blood-2024-208106

Published: 2024

Journal Articles

Pharmacological Targeting of the Heme-Regulated Inhibitor Kinase Overcomes Ineffective Erythropoiesis in Patients with Myelodysplastic Syndromes with Ringed Sideroblasts and Sickle Cell Disease

Vera Adema, Giulia Faccincani, Amy Cooper, Juan Jose Rodriguez-Sevilla, Jieqing Chen, Natthakan Thongon, Teresa Perry, Jennifer Tran, Fernando Alvarez, Zhijun Kang, Vijayan Ramaswamy, Roopa Thapar, Troy Johnson, Guillermo Garcia-Manero, Faika Mseeh, David Kummer, Philip Jones, Timothy Heffernan, Simona Colla

Blood (2024) 144 (Supplement 1): 153.

https://doi.org/10.1182/blood-2024-205770

Published: 2024

Journal Articles

Novel p53 Mutant Mouse Model Recapitulates the Biology of Human Therapy-Related Myeloid Neoplasms

Rasoul Pourebrahim, Dexin Yang, Priyanka Khanna, Muharrem Muftuoglu, Lauren B. Ostermann, Shayaun Khazaei, Ran Zhao, Mihai Gagea, Simona Colla, Guillermo Garcia-Manero, Ruoyan Li, Michael Andreeff, Koichi Takahashi

Blood (2024) 144 (Supplement 1): 882.

https://doi.org/10.1182/blood-2024-207582

Published: 2024

Journal Articles

T-cell dysfunctions in myelodysplastic syndromes

Juan Jose Rodriguez-Sevilla, Simona Colla

Blood (2024) 143 (14): 1329–1343.

https://doi.org/10.1182/blood.2023023166

Published: 2024

Includes: Supplemental data

Journal Articles

A road map of relapse in MDS after allo-HSCT

Juan Jose Rodriguez-Sevilla, Simona Colla

Blood (2024) 143 (11): 941–943.

https://doi.org/10.1182/blood.2023023533

Published: 2024

Journal Articles

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones

Blood (2023) 142 (Supplement 1): 514.

https://doi.org/10.1182/blood-2023-184349

Published: 2023

Journal Articles

Blood Count Recovery and Telomere Elongation in a TINF2 Patient Under Treatment with a Gonadotropin-Releasing Hormone (GnRH) Agonist

Fernanda Gutierrez-Rodrigues, Natthakan Thongon, Christopher L Williams, Simona Colla, Neal S. Young, Alison A. Bertuch

Blood (2023) 142 (Supplement 1): 2735.

https://doi.org/10.1182/blood-2023-190210

Published: 2023

Journal Articles

Myelodysplastic Syndrome Hematopoietic Stem Cells Can Undergo Differentiation Trajectory Rewiring to Escape Venetoclax Vulnerability

Juan Jose Rodriguez Sevilla, Irene Ganan-Gomez, Feiyang Ma, Kelly S. Chien, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Sanam Loghavi, Vera Adema, Natthakan Thongon, Alexandre Bazinet, Guillermo Garcia-Manero, Simona Colla

Blood (2023) 142 (Supplement 1): 584.

https://doi.org/10.1182/blood-2023-180447

Published: 2023

Journal Articles

Oral Decitabine/Cedazuridine with Venetoclax in High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia: Analysis By Different Response Criteria

Blood (2023) 142 (Supplement 1): 3228.

https://doi.org/10.1182/blood-2023-189203

Published: 2023

Journal Articles

Orthogonal Proteogenomic Approaches Identify the Druggable PA2G4-MYC Axis in 3q26 AML

Matteo Marchesini, Andrea Gherli, Elisa Simoncini, Anna Montanaro, Natthakan Thongon, Luca Pagliaro, Federica Vento, Lucas Moron Dalla Tor, Chiara Liverani, Raffaella Zamponi, Elena Follini, Benedetta Cambò, Bruno Lorusso, Roberta La Starza, Antonio Cuneo, Cristina Mecucci, Simona Colla, Federico Quaini, Giovanni Roti

Blood (2022) 140 (Supplement 1): 673–674.

https://doi.org/10.1182/blood-2022-158990

Published: 2022

Journal Articles

Dual BCL-XL/2 Protac 753B Not Only Potently Induces Apoptosis in Venetoclax-Resistant Primary AML Cells but Also Effectively Eliminates Chemotherapy-Induced Senescent AML Cells

Yannan Jia, Lina Han, Cassandra L Ramage, Connie C. Weng, Lei Yang, Simona Colla, Helen Ma, Weiguo Zhang, Michael Andreeff, Naval Daver, Nitin Jain, Naveen Pemmaraju, Kapil N. Bhalla, Satu Mustjoki, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Qi Zhang, Marina Konopleva

Blood (2022) 140 (Supplement 1): 3347–3349.

https://doi.org/10.1182/blood-2022-164541

Published: 2022

Journal Articles

Clinical and Biological Effects of Canakinumab in Lower-Risk Myelodysplastic Syndromes (MDS): Results from a Phase 2 Clinical Trial

Guillermo Garcia-Manero, Vera Adema, Samuel Urrutia, Feiyang Ma, Hui Yang, Irene Ganan-Gomez, Gautam Borthakur, Koichi Takahashi, Nicholas Short, Ghayas C. Issa, Kelly S. Chien, Guillermo Montalban-Bravo, Joby Joseph, Simona Colla

Blood (2022) 140 (Supplement 1): 2078–2080.

https://doi.org/10.1182/blood-2022-167703

Published: 2022

Journal Articles

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Blood (2022) 140 (Supplement 1): 2232–2233.

https://doi.org/10.1182/blood-2022-160294

Published: 2022

Journal Articles

STAT3 Protects Hematopoietic Stem and Progenitor Cell Function in Non-Inflamed Conditions

Bhakti Patel, Yifan Zhou, Rachel L Babcock, Feiyang Ma, Yusra B Medik, Laura M Kahn, Josue E Pineda, Elizabeth Park, Karen Clise-Dwyer, Simona Colla, Stephanie S Watowich

Blood (2022) 140 (Supplement 1): 2864–2865.

https://doi.org/10.1182/blood-2022-170250

Published: 2022

Journal Articles

Genomic Evolution of Patients with Myelodysplastic Syndrome after Hypomethylating Agent Failure

Blood (2022) 140 (Supplement 1): 9773–9775.

https://doi.org/10.1182/blood-2022-169213

Published: 2022

Journal Articles

Transcriptomic Signitures of Azacitidine (AZA) and Decitabine (DAC) Resistance in MDS and CMML

Faezeh Darbaniyan, Caleb Class, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Marcos Estecio, Yue Lu, Kelly A. Soltysiak, Kelly S. Chien, Hui Yang, Koji Sasaki, Irene Ganan-Gomez, Simona Colla, Kim-Anh Do, Guillermo Garcia-Manero, Yue Wei

Blood (2021) 138 (Supplement 1): 4652.

https://doi.org/10.1182/blood-2021-153698

Published: 2021

NARROW

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

A Single-Cell T-Cell Reference Map Delineates the Biological Landscape of CD4 + T Cells in Myelodysplastic Syndromes Under Venetoclax Therapy

Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms

T Lymphopenia and Aged Immune System Characterize Immunodeficiency in Adult Patients with Telomere Biology Disorders

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Pharmacological Targeting of the Heme-Regulated Inhibitor Kinase Overcomes Ineffective Erythropoiesis in Patients with Myelodysplastic Syndromes with Ringed Sideroblasts and Sickle Cell Disease

Novel p53 Mutant Mouse Model Recapitulates the Biology of Human Therapy-Related Myeloid Neoplasms

T-cell dysfunctions in myelodysplastic syndromes

A road map of relapse in MDS after allo-HSCT

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones

Blood Count Recovery and Telomere Elongation in a TINF2 Patient Under Treatment with a Gonadotropin-Releasing Hormone (GnRH) Agonist

Myelodysplastic Syndrome Hematopoietic Stem Cells Can Undergo Differentiation Trajectory Rewiring to Escape Venetoclax Vulnerability

Oral Decitabine/Cedazuridine with Venetoclax in High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia: Analysis By Different Response Criteria

Orthogonal Proteogenomic Approaches Identify the Druggable PA2G4-MYC Axis in 3q26 AML

Dual BCL-XL/2 Protac 753B Not Only Potently Induces Apoptosis in Venetoclax-Resistant Primary AML Cells but Also Effectively Eliminates Chemotherapy-Induced Senescent AML Cells

Clinical and Biological Effects of Canakinumab in Lower-Risk Myelodysplastic Syndromes (MDS): Results from a Phase 2 Clinical Trial

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

STAT3 Protects Hematopoietic Stem and Progenitor Cell Function in Non-Inflamed Conditions

Genomic Evolution of Patients with Myelodysplastic Syndrome after Hypomethylating Agent Failure

Transcriptomic Signitures of Azacitidine (AZA) and Decitabine (DAC) Resistance in MDS and CMML

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American Society of Hematology

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ASH Publications

American Society of Hematology

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