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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Blood (2024) 144 (23): 2402–2416.

https://doi.org/10.1182/blood.2024025023

Published: 2024

Includes: Supplemental data

Journal Articles

T Cell Receptor Clonal Dynamics and Hematopoietic Recovery after Immunotherapy in Severe Aplastic Anemia

Zhijie Wu, Shouguo Gao, Xingmin Feng, Haoran Li, Nicolas Sompairac, Shirin Jamshidi, Desmond Choy, Rita Antunes Dos Reis, Qingyan Gao, Sachiko Kajigaya, Lemlem Alemu, Diego Quinones Raffo, Emma M. Groarke, Shahram Kordasti, Bhavisha A. Patel, Neal S. Young

Blood (2024) 144 (Supplement 1): 34.

https://doi.org/10.1182/blood-2024-203468

Published: 2024

Journal Articles

Single-Cell Multi-Omics Analysis Reveals Dysfunctional Features of the Immune Responses in Vexas Syndrome

Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Xingmin Feng, Fernanda Gutierrez-Rodrigues, Lemlem Alemu, Diego Quinones Raffo, Ivana Darden, Sachiko Kajigaya, Emma M. Groarke, Neal S. Young, Bhavisha A. Patel

Blood (2024) 144 (Supplement 1): 4056.

https://doi.org/10.1182/blood-2024-198166

Published: 2024

Journal Articles

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Emma M. Groarke, Lemlem Alemu, Diego Quinones Raffo, Olga Rios, Sachiko Kajigaya, Bhavisha A. Patel, Neal S. Young

Blood (2023) 142 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2023-181078

Published: 2023

Journal Articles

Spectrum of clonal hematopoiesis in VEXAS syndrome

Blood (2023) 142 (3): 244–259.

https://doi.org/10.1182/blood.2022018774

Published: 2023

Includes: Supplemental data

Journal Articles

Differential diagnosis of bone marrow failure syndromes guided by machine learning

Blood (2023) 141 (17): 2100–2113.

https://doi.org/10.1182/blood.2022017518

Published: 2023

Includes: Supplemental data

Journal Articles

Oligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T therapy for Richter-transformed DLBCL

Kai Rejeski, Zhijie Wu, Viktoria Blumenberg, Wolfgang G. Kunz, Susanna Müller, Sachiko Kajigaya, Shouguo Gao, Veit L. Bücklein, Lisa Frölich, Christian Schmidt, Michael von Bergwelt-Baildon, Xingmin Feng, Neal S. Young, Marion Subklewe

Blood (2022) 140 (20): 2175–2179.

https://doi.org/10.1182/blood.2022017015

Published: 2022

Includes: Supplemental data

Journal Articles

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia

Yoshitaka Zaimoku, Bhavisha A. Patel, Sharon D. Adams, Ruba Shalhoub, Emma M. Groarke, Audrey Ai Chin Lee, Sachiko Kajigaya, Xingmin Feng, Olga Julia Rios, Holly Eager, Lemlem Alemu, Diego Quinones Raffo, Colin O. Wu, Willy A. Flegel, Neal S. Young

Blood (2021) 138 (26): 2799–2809.

https://doi.org/10.1182/blood.2021012895

Published: 2021

Includes: Supplemental data

Journal Articles

Genomic-Based Machine Learning Towards Prediction of the Etiology of Bone Marrow Failure Syndromes

Blood (2021) 138 (Supplement 1): 2182.

https://doi.org/10.1182/blood-2021-151258

Published: 2021

Journal Articles

Clonal Hematopoiesis in Telomere Biology Disorders Associates with the Underlying Germline Defect and Somatic Mutations in POT1 , PPM1D, and TERT promoter

Fernanda Gutierrez-Rodrigues, Emma M Groarke, Diego V Clé, Bhavisha A. Patel, Flávia S Donaires, Nina Spitofsky, Lemlem Alemu, Bárbara A Santana, Sachiko Kajigaya, Simona Colla, Michel Michels De Oliveira, Carmem M. S. Bonfim, Rodrigo T. Calado, Neal S. Young

Blood (2021) 138 (Supplement 1): 1111.

https://doi.org/10.1182/blood-2021-151199

Published: 2021

Journal Articles

Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis

Fernanda Gutierrez-Rodrigues, PhD, Isabel Beerman, PhD, Emma M. Groarke, MD, Bhavisha A Patel, MD, Nina Spitofsky, Diego Quinones Raffo, MSc, Sachiko Kajigaya, PhD, Luigi Ferrucci, MD PhD, Neal S. Young, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-139874

Published: 2020

Journal Articles

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Qingguo Liu, MD PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Fengkui Zhang, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 4997.

https://doi.org/10.1182/blood-2019-123249

Published: 2019

Journal Articles

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Shouguo Gao, PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3706.

https://doi.org/10.1182/blood-2019-123204

Published: 2019

Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3735.

https://doi.org/10.1182/blood-2019-124774

Published: 2019

Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3738.

https://doi.org/10.1182/blood-2019-127359

Published: 2019

Journal Articles

Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes

Naoki Watanabe, Shouguo Gao, PhD, Sachiko Kajigaya, Carrie Diamond, MD, Lemlem Alemu, BS, Amanda Ombrello, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 2317.

https://doi.org/10.1182/blood-2019-123859

Published: 2019

Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Fernanda Gutierrez-Rodrigues, PhD, Flávia S Donaires, PhD, André Pinto, Alana Vicente, MD, Laura Dillon, PhD, Diego V Clé, MDPhD, Bárbara Santana, Maria del Pilar Fernandez Ibanez, Danielle M. Townsley, MD MSc, Sachiko Kajigaya, PhD, Christopher S. Hourigan, DPhil FACP FRCP, James N. Cooper, MD, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 539.

https://doi.org/10.1182/blood-2018-99-115430

Published: 2018

Journal Articles

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Shouguo Gao, PhD, Zhijie Wu, MD PhD, Carrie Diamond, MD, Bradley Arnold, BS, Valentina Giudice, MD, Lemlem Alemu, BS, John Barrett, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2404.

https://doi.org/10.1182/blood-2018-99-115166

Published: 2018

Journal Articles

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Fernanda Gutierrez-Rodrigues, PhD, Carrie Diamond, MD, Ruba Shalhoub, André Pinto, Flávia S Donaires, PhD, Diego V Clé, MD PhD, Luiz Guilherme Darrigo, PhD, Luiz Fernando Catto, MD, Xing Fan, MD, Maria del Pilar Fernandez Ibanez, Sachiko Kajigaya, PhD, Cynthia E. Dunbar, MD, Carmem M. S. Bonfim, MD, Danielle M. Townsley, MD MSc, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2587.

https://doi.org/10.1182/blood-2018-99-115026

Published: 2018

NARROW

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

T Cell Receptor Clonal Dynamics and Hematopoietic Recovery after Immunotherapy in Severe Aplastic Anemia

Single-Cell Multi-Omics Analysis Reveals Dysfunctional Features of the Immune Responses in Vexas Syndrome

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Spectrum of clonal hematopoiesis in VEXAS syndrome

Differential diagnosis of bone marrow failure syndromes guided by machine learning

Oligoclonal T-cell expansion in a patient with bone marrow failure after CD19 CAR-T therapy for Richter-transformed DLBCL

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia

Genomic-Based Machine Learning Towards Prediction of the Etiology of Bone Marrow Failure Syndromes

Clonal Hematopoiesis in Telomere Biology Disorders Associates with the Underlying Germline Defect and Somatic Mutations in POT1 , PPM1D, and TERT promoter

Clinical Utility of Plasma Cell-Free DNA for Detection and Quantification of Clonal Hematopoiesis

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Analysis of Deficiency of Adenosine Deaminase 2 Pathogenesis Based on Single Cell RNA Sequencing of Monocytes

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Somatic TERT promoter Mutations in a Broad Spectrum of Telomeropathies

Single Cell RNA Sequencing and V(D)J Profiling of T-Cell Large Granular Lymphocytosis

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

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American Society of Hematology

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American Society of Hematology

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