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Katherine R. Calvo
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Journal Articles

CD74 Signaling Regulates Inflammatory Stress to Drive Defective Hematopoiesis and Fitness Advantage of Progenitors in RUNX1-Familial Platelet Disorder

Mona M.Hosseini, Trevor Enright, Adam S. Duvall, Alex Chitsazan, Hsin-Yun Lin, Aysegul Ors, Brett Davis, Olga Nikolova, Erica Bresciani, Jamie Lynn Diemer, Kathleen Craft, Catarina Menezes, Matthew Merguerian, Shawn Chong, Katherine R. Calvo, Shira Glushakow-Smith, Kira Gritsman, Lucy Godley, Marshall S Horwitz, Sioban Keel, Lucio H. Castilla, Emek Demir, Hisham Mohammed, Paul P. Liu, Anupriya Agarwal
Journal: Blood
Blood (2024) 144 (Supplement 1): 198.
https://doi.org/10.1182/blood-2024-211542
Published: 2024
Journal Articles

Usefulness of EHR-Linked Biobanks in Variant Classification for Myeloid Neoplasms

Huan Mo, Tracey M. Ferrara, Kalpana Upadhyaya, Katherine R. Calvo, Joshua C. Denny
Journal: Blood
Blood (2024) 144 (Supplement 1): 6574.
https://doi.org/10.1182/blood-2024-204137
Published: 2024
Journal Articles

Rituximab Reduces Immunogenicity and Increases Complete Remissions without Minimal Residual Disease in Relapsed/Refractory Hairy Cell Leukemia Patients Receiving Moxetumomab Pasudotox

Robert J. Kreitman, Constance M. Yuan, Hao-Wei Wang, Hong Zhou, Mark Raffeld, Liqiang Xi, Evgeny Arons, Julie Feurtado, Lacey James, Raul C. Braylan, Katherine R. Calvo, Irina Maric, Ira Pastan
Journal: Blood
Blood (2024) 144 (Supplement 1): 6791.
https://doi.org/10.1182/blood-2024-199569
Published: 2024
Journal Articles

A Randomized Phase 2 Trial of 2nd-Line Cladribine with Concurrent or Delayed Rituximab in Patients with Classic Hairy Cell Leukemia

Robert J. Kreitman, Hao-Wei Wang, Dana I. Delgado Colon, Hong Zhou, Evgeny Arons, Mark Raffeld, Liqiang Xi, Julie Feurtado, Lacey James, Raul C. Braylan, Katherine R. Calvo, Irina Maric, Constance M. Yuan
Journal: Blood
Blood (2024) 144 (Supplement 1): 863.
https://doi.org/10.1182/blood-2024-202793
Published: 2024
Journal Articles

A Phase 2 Response-Adapted Study of Daratumumab, Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple Myeloma

Roshani Patel, Amrit Bhaskarla, Max J Gordon, Michael Emanuel, Dana I. Delgado Colon, Hao-Wei Wang, Constance M. Yuan, Liza Lindenberg, Esther Mena, Baris Turkbey, Nick Micheletti, Laura M Yee, Nisha Patel, Irina Maric, Raul C. Braylan, Katherine R. Calvo, Louis M. Staudt, Ryan M. Young, Mark Roschewski, Dickran Kazandjian, Elizabeth Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 7059.
https://doi.org/10.1182/blood-2024-201563
Published: 2024
Journal Articles

Recipient-Derived Hematopoietic Cells Are the Source of Hematologic Malignancies after Graft Failure and Mixed Chimerism in Adults with Sickle Cell Disease

Mohamed Ali, Emily Limerick, Matthew Hsieh, Kalpana Upadhyaya, Xin Xu, Oswald Phang, Jean Pierre Kambala Mukendi, Katherine R. Calvo, Maria Lopez-Ocasio, Pradeep Dagur, Courtney Fitzhugh
Journal: Blood
Blood (2024) 144 (Supplement 1): 2167.
https://doi.org/10.1182/blood-2024-207487
Published: 2024
Journal Articles

Venous and arterial thrombosis in patients with VEXAS syndrome

Clinical Trials & Observations
Yael Kusne, Atefeh Ghorbanzadeh, Alina Dulau-Florea, Ruba Shalhoub, Pedro E. Alcedo, Khanh Nghiem, Marcela A. Ferrada, Alexander Hines, Kaitlin A. Quinn, Sumith R. Panicker, Amanda K. Ombrello, Kaaren Reichard, Ivana Darden, Wendy Goodspeed, Jibran Durrani, Lorena Wilson, Horatiu Olteanu, Terra Lasho, Daniel L. Kastner, Kenneth J. Warrington, Abhishek Mangaonkar, Ronald S. Go, Raul C. Braylan, David B. Beck, Mrinal M. Patnaik, Neal S. Young, Katherine R. Calvo, Ana I. Casanegra, Peter C. Grayson, Matthew J. Koster, Colin O. Wu, Yogendra Kanthi, Bhavisha A. Patel, Damon E. Houghton, Emma M. Groarke
Journal: Blood
Blood (2024) 143 (21): 2190–2200.
https://doi.org/10.1182/blood.2023022329
Published: 2024
Includes: Supplemental data
Journal Articles

Natural history study of patients with familial platelet disorder with associated myeloid malignancy

CME Clinical Trials & Observations
Lea Cunningham, Matthew Merguerian, Katherine R. Calvo, Joie Davis, Natalie T. Deuitch, Alina Dulau-Florea, Nisha Patel, Kai Yu, Keith Sacco, Sumona Bhattacharya, Monica Passi, Neval Ozkaya, Seila De Leon, Shawn Chong, Kathleen Craft, Jamie Diemer, Erica Bresciani, Kevin O’Brien, Elizabeth J. Andrews, Nguyen Park, Londa Hathaway, Edward W. Cowen, Theo Heller, Kerry Ryan, Amisha Barochia, Khanh Nghiem, Julie Niemela, Sergio Rosenzweig, David J. Young, Pamela A. Frischmeyer-Guerrerio, Raul Braylan, Paul P. Liu
Journal: Blood
Blood (2023) 142 (25): 2146–2158.
https://doi.org/10.1182/blood.2023019746
Published: 2023
Includes: Supplemental data
Journal Articles

Bone Marrow, Laboratory, and Clinical Features in Pediatric Patients with RUNX1 Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)

Seila De Leon, Michelly Sampaio De Melo, Nisha Patel, Alina Dulau Florea, Irina Maric, Raul C. Braylan, Weixin Wang, Matthew Merguerian, Elizabeth J. Andrews, Lea Cunningham, David J. Young, Shawn Chong, Natalie Deuitch, Joie Davis, Kathleen Craft, Theo Heller, Pamela Frischmeyer-Guerrerio, Paul Pu Liu, Katherine R. Calvo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4109.
https://doi.org/10.1182/blood-2023-187600
Published: 2023
Journal Articles

Interplay between Inflammatory Microenvironment and RUNX1-Mediated Transcriptomic Changes Drives Defective Hematopoiesis in Familial Platelet Disorder

Mona M.Hosseini, Trevor Enright, Adam S Duvall, Alex Chitsazan, Hsin-Yun Lin, Aysegul Ors, Brett Davis, Joseph Estabrook, Olga Nikolova, Jamie Lynn Diemer, Kathleen Craft, Erica Bresciani, Katherine R. Calvo, Matthew Merguerian, Marshall Horwitz, Sioban Keel, Lucy Godley, Lucio H. Castilla, Emek Demir, Hisham Mohammed, Paul Pu Liu, Anupriya Agarwal
Journal: Blood
Blood (2023) 142 (Supplement 1): 945.
https://doi.org/10.1182/blood-2023-187750
Published: 2023
Journal Articles

Spectrum of clonal hematopoiesis in VEXAS syndrome

CME
Fernanda Gutierrez-Rodrigues, Yael Kusne, Jenna Fernandez, Terra Lasho, Ruba Shalhoub, Xiaoyang Ma, Hugh Alessi, Christy Finke, Matthew J. Koster, Abhishek Mangaonkar, Kenneth J. Warrington, Kebede Begna, Zhuoer Xie, Amanda K. Ombrello, David Viswanatha, Marcela Ferrada, Lorena Wilson, Ronald Go, Taxiarchis Kourelis, Kaaren Reichard, Horatiu Olteanu, Ivana Darden, Dalton Hironaka, Lemlem Alemu, Sachiko Kajigaya, Sofia Rosenzweig, Rodrigo T. Calado, Emma M. Groarke, Daniel L. Kastner, Katherine R. Calvo, Colin O. Wu, Peter C. Grayson, Neal S. Young, David B. Beck, Bhavisha A. Patel, Mrinal M. Patnaik
Journal: Blood
Blood (2023) 142 (3): 244–259.
https://doi.org/10.1182/blood.2022018774
Published: 2023
Includes: Supplemental data
Journal Articles

The spectrum of GATA2 deficiency syndrome

Katherine R. Calvo, Dennis D. Hickstein
Journal: Blood
Blood (2023) 141 (13): 1524–1532.
https://doi.org/10.1182/blood.2022017764
Published: 2023
Journal Articles

A RUNX1 -FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies

Brief Report
Byung-Chul Lee, Yifan Zhou, Erica Bresciani, Neval Ozkaya, Alina Dulau-Florea, Blake Carrington, Tae-Hoon Shin, Valentina Baena, Zulfeqhar A. Syed, So Gun Hong, Tao Zhen, Katherine R. Calvo, Paul Liu, Cynthia E. Dunbar
Journal: Blood
Blood (2023) 141 (3): 231–237.
https://doi.org/10.1182/blood.2022018193
Published: 2023
Includes: Supplemental data
Journal Articles

Eosinophilia in Vexas Syndrome: Expanding Hematologic Phenotype

Ashvind Anand Prabahran, Fernanda Gutierrez-Rodrigues, Serene Ahmad, Edward W Cowen, Ivana Darden, Emma M. Groarke, Marcela Ferrada, Peter C. Grayson, Amy D Klion, Katherine R. Calvo, Irina Maric, Neal S. Young, Bhavisha A. Patel
Journal: Blood
Blood (2022) 140 (Supplement 1): 2607–2608.
https://doi.org/10.1182/blood-2022-160287
Published: 2022
Journal Articles

Abnormal Cytotoxic T-Cell Expansion in the Bone Marrow of Patients with SASH3 Deficiency and Cytopenias

Saber Tadros, Shamik Majumdar, Ottavia Delmonte, Jenna Bergerson, Irene Cortese, David H. McDermott, Jaspal Khillan, Kyoungin Cho, Luigi D. Notarangelo, Philip M. Murphy, Katherine R. Calvo
Journal: Blood
Blood (2022) 140 (Supplement 1): 1650–1651.
https://doi.org/10.1182/blood-2022-167673
Published: 2022
Journal Articles

Thrombotic Manifestations in Patients with Vexas Syndrome

Pedro E. Alcedo Andrade, Ruba Shalhoub, Alina Dulau-Florea, Khanh Nghiem, Marcela Ferrada, Lorena Wilson, Ivana Darden, Wendy Goodspeed, Katherine R. Calvo, David B. Beck, Daniel L. Kastner, Peter C. Grayson, Neal S. Young, Colin O. Wu, Yogendra Kanthi, Bhavisha A. Patel, Emma M. Groarke
Journal: Blood
Blood (2022) 140 (Supplement 1): 2788–2789.
https://doi.org/10.1182/blood-2022-163608
Published: 2022
Journal Articles

Spatial-Temporal Multiomic Analysis of Tumor-Immune Interactions in Patients with AML Receiving Pembrolizumab and Decitabine

Gege Gui, Abigail Wong-Rolle, Laura W. Dillon, Meghali Goswami, Eddie Martin, Prajan Divakar, Jason Reeves, Katherine R. Calvo, Kasper D. Hansen, Christopher S. Hourigan, Chen Zhao
Journal: Blood
Blood (2022) 140 (Supplement 1): 3427–3428.
https://doi.org/10.1182/blood-2022-168191
Published: 2022
Journal Articles

Clonal Hematopoiesis in Vexas Syndrome

Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Yael Kusne, Jenna A. Fernandez, Terra Lasho, Ruba Shalhoub, Xiaoyang Ma, Hugh Alessi, Christy Finke, Matthew Koster, Abhishek A. Mangaonkar, Kenneth Warrington, Kebede H. Begna, Zhuoer Xie, Amanda Ombrello, David S. Viswanatha, Marcela Ferrada, Lorena Wilson, Ronald Go, Taxiarchis Kourelis, Kaaren K. Reichard, Horatiu Olteanu, Emma M. Groarke, Ivana Darden, Dalton Hironaka, Sofia Rosenzweig, Daniel L. Kastner, Katherine R. Calvo, Colin O. Wu, Peter C. Grayson, David B. Beck, Mrinal M.M. Patnaik, Neal S. Young
Journal: Blood
Blood (2022) 140 (Supplement 1): 5745–5746.
https://doi.org/10.1182/blood-2022-160263
Published: 2022
Journal Articles

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes, Max Z. Grice, Xing Fan, Byung-Chul Lee, Aisha A. Aljanahi, So Gun Hong, Kelli L. Vaughan, Julie A. Mattison, Steven G. Kohama, Margarete A. Fabre, Naoya Uchida, Selami Demirci, Marcus A. F. Corat, Jean-Yves Métais, Katherine R. Calvo, Manuel Buscarlet, Hannah Natanson, Kathy L. McGraw, Alan F. List, Lambert Busque, John F. Tisdale, George S. Vassiliou, Kyung-Rok Yu, Cynthia E. Dunbar
Journal: Blood
Blood (2022) 140 (16): 1774–1789.
https://doi.org/10.1182/blood.2021014875
Published: 2022
Includes: Supplemental data
Journal Articles

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis

Marcela A. Ferrada, Sinisa Savic, Daniela Ospina Cardona, Jason C. Collins, Hugh Alessi, Fernanda Gutierrez-Rodrigues, Dinesh Babu Uthaya Kumar, Lorena Wilson, Wendy Goodspeed, James S. Topilow, Julie J. Paik, James A. Poulter, Tanaz A. Kermani, Matthew J. Koster, Kenneth J. Warrington, Catherine Cargo, Rachel S. Tattersall, Christopher J. A. Duncan, Anna Cantor, Patrycja Hoffmann, Elspeth M. Payne, Hanna Bonnekoh, Karoline Krause, Edward W. Cowen, Katherine R. Calvo, Bhavisha A. Patel, Amanda K. Ombrello, Daniel L. Kastner, Neal S. Young, Achim Werner, Peter C. Grayson, David B. Beck
Journal: Blood
Blood (2022) 140 (13): 1496–1506.
https://doi.org/10.1182/blood.2022016985
Published: 2022
Includes: Supplemental data