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Kyung-Rok Yu
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Journal Articles

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes, Max Z. Grice, Xing Fan, Byung-Chul Lee, Aisha A. Aljanahi, So Gun Hong, Kelli L. Vaughan, Julie A. Mattison, Steven G. Kohama, Margarete A. Fabre, Naoya Uchida, Selami Demirci, Marcus A. F. Corat, Jean-Yves Métais, Katherine R. Calvo, Manuel Buscarlet, Hannah Natanson, Kathy L. McGraw, Alan F. List, Lambert Busque, John F. Tisdale, George S. Vassiliou, Kyung-Rok Yu, Cynthia E. Dunbar
Journal: Blood
Blood (2022) 140 (16): 1774–1789.
https://doi.org/10.1182/blood.2021014875
Published: 2022
Includes: Supplemental data
Journal Articles

Macaque CRISPR/Cas9 Age-Related Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Mutated Clones and Applicability for Testing Mitigation Approaches

Taehoon Shin, Shirley Chen, BS, Stefan Cordes, MD PhD, Yifan Zhou, MS, Byung-Chul Lee, PhD, Aisha Aljanahi, BS, So Gun Hong, PhD, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-140770
Published: 2020
Journal Articles

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

Tae-Hoon Shin, Eun Jung Baek, Marcus A. F. Corat, Shirley Chen, Jean-Yves Metais, Aisha A. AlJanahi, Yifan Zhou, Robert E. Donahue, Kyung-Rok Yu, Cynthia E. Dunbar
Journal: Blood
Blood (2019) 133 (23): 2542–2545.
https://doi.org/10.1182/blood.2019000800
Published: 2019
Includes: Supplemental data
Journal Articles

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Taehoon Shin, PhD, Eun Jung Baek, MD, Marcus A.F. Corat, PhD, Shirley Chen, BS, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1309.
https://doi.org/10.1182/blood-2018-99-111984
Published: 2018
Journal Articles

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Kyung-Rok Yu, Diego A. Espinoza, Chuanfeng Wu, Lauren Truitt, Tae-Hoon Shin, Shirley Chen, Xing Fan, Idalia M. Yabe, Sandhya Panch, So Gun Hong, Samson Koelle, Rong Lu, Aylin Bonifacino, Allen Krouse, Mark Metzger, Robert E. Donahue, Cynthia E. Dunbar
Journal: Blood
Blood (2018) 131 (11): 1195–1205.
https://doi.org/10.1182/blood-2017-08-802033
Published: 2018
Includes: Supplemental data
Journal Articles

A Non-Human Primate CRISPR/Cas9 Model of Clonal Hematopoiesis of Indeterminate Potential Demonstrates Expansion of TET2-Disrupted Clones

Kyung-Rok Yu, PhD, Cynthia E Dunbar, MD, Marcus Corat, Shirley Chen, Aisha Aljanahi, Eun Jung Baek, Jean-Yves Metais, Hannah Natanson, Thomas Winkler, MD, Robert E Donahue, VMD
Journal: Blood
Blood (2017) 130 (Supplement 1): 117.
https://doi.org/10.1182/blood.V130.Suppl_1.117.117
Published: 2017
Journal Articles

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Kyung-Rok Yu, PhD, Chuanfeng Wu, PhD, Diego Espinoza, Idalia Yabe, Sandhya R. Panch, MD MPH, So Gun Hong, PhD, Samson Jonathan Koelle, BA, Rong Lu, Aylin Bonifacino, Alan Krouse, Mark Metzger, Robert Donahue, VMD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2015) 126 (23): 1151.
https://doi.org/10.1182/blood.V126.23.1151.1151
Published: 2015