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Journal Articles

CD117 Antibody Conditioning and Multiplex Base Editing Enable Rapid and Robust Fetal Hemoglobin Reactivation in a Rhesus Autologous Transplantation Model

Blood (2024) 144 (Supplement 1): 516.

https://doi.org/10.1182/blood-2024-204403

Published: 2024

Journal Articles

CD117 Antibody-Drug Conjugate Conditioning Allows Efficient Engraftment of Gene-Modified CD34+ Cells with Fertility Preservation in a Rhesus Gene Therapy Model

Blood (2023) 142 (Supplement 1): 486.

https://doi.org/10.1182/blood-2023-177815

Published: 2023

Journal Articles

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Naoya Uchida, MD, Linhong Li, PhD, Tina Nassehi, Morgan Yapundich, Jackson Gamer, Claire Drysdale, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Cornell Allen, MS, Suk See De Ravin, MD, PhD, Robert E. Donahue, VMD, Harry L. Malech, MD, Madhusudan Peshwa, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 609.

https://doi.org/10.1182/blood-2019-122727

Published: 2019

Journal Articles

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Naoya Uchida, MD, Claire Drysdale, Morgan Yapundich, Jackson Gamer, Tina Nassehi, Matthew Wielgosz, Francesca Ferrara, PhD, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Robert E. Donahue, VMD, Byoung Y. Ryu, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 2063.

https://doi.org/10.1182/blood-2019-122770

Published: 2019

Journal Articles

Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques

Sanggu Kim, PhD, Robert E. Donahue, VMD, Aylin Bonifacino, MS, Mark Metzger, Cynthia E. Dunbar, MD, Irvin Chen, PhD

Blood (2018) 132 (Supplement 1): 4524.

https://doi.org/10.1182/blood-2018-99-117047

Published: 2018

Journal Articles

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

Blood (2018) 132 (Supplement 1): 5677.

https://doi.org/10.1182/blood-2018-99-114730

Published: 2018

Journal Articles

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Kyung-Rok Yu, Diego A. Espinoza, Chuanfeng Wu, Lauren Truitt, Tae-Hoon Shin, Shirley Chen, Xing Fan, Idalia M. Yabe, Sandhya Panch, So Gun Hong, Samson Koelle, Rong Lu, Aylin Bonifacino, Allen Krouse, Mark Metzger, Robert E. Donahue, Cynthia E. Dunbar

Blood (2018) 131 (11): 1195–1205.

https://doi.org/10.1182/blood-2017-08-802033

Published: 2018

Includes: Supplemental data

Journal Articles

Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque

Diego A Espinoza, BA, Chuanfeng Wu, MD, Xing Fan, MD, Di Yang, MD, Idalia Montano Yabe, MS, Selami Demirci, PhD, So Gun Hong, PhD, Aylin Bonifacino, MS, Allen Krouse, Mark Metzger, Rong Lu, PhD, Katherine R Calvo, MD PhD, John F Tisdale, MD, Xiaolin Wu, PhD, Suk See De Ravin, MD PhD, Harry L Malech, MD, Robert E Donahue, VMD, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 606.

https://doi.org/10.1182/blood.V130.Suppl_1.606.606

Published: 2017

Journal Articles

Skewed HSC Clonal Output of T-Cells in an Aged Rhesus Macaque after CD3e-Immunotoxin Treatment

Sanggu Kim, PhD, Gajendra Suryavanshi, PhD, Aylin Bonifacino, MS, Chuanfeng Wu, MD, Cynthia E Dunbar, MD, Robert E Donahue, VMD, Irvin Chen, PhD

Blood (2017) 130 (Supplement 1): 3758.

https://doi.org/10.1182/blood.V130.Suppl_1.3758.3758

Published: 2017

Journal Articles

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Xing Fan, MD, Chuanfeng Wu, MD, Diego Espinoza, Stephanie Sellers, Aylin Bonifacino, MS, Robert E Donahue, VMD, Luca Schifanella, Genoveffa Franchini, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 932.

https://doi.org/10.1182/blood.V130.Suppl_1.932.932

Published: 2017

Journal Articles

Bone Marrow Characterization in Sickle Cell Disease: Inflammation and Stress Erythropoiesis Lead to Suboptimal CD34 Recovery Compared to Normal Volunteer Bone Marrow

Alexis Leonard, MD, Aylin Bonifacino, MS, Venina Marcela Dominical, PhD, Anna Conrey, NP, Wynona Coles, Mary Link, RN, Matthew Hsieh, MD, Min Luo, PhD, Naoya Uchida, MD PhD, Francis J. Pierciey, Jr., John F Tisdale, MD

Blood (2017) 130 (Supplement 1): 966.

https://doi.org/10.1182/blood.V130.Suppl_1.966.966

Published: 2017

Journal Articles

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Kyung-Rok Yu, PhD, Chuanfeng Wu, PhD, Diego Espinoza, Idalia Yabe, Sandhya R. Panch, MD MPH, So Gun Hong, PhD, Samson Jonathan Koelle, BA, Rong Lu, Aylin Bonifacino, Alan Krouse, Mark Metzger, Robert Donahue, VMD, Cynthia E. Dunbar, MD

Blood (2015) 126 (23): 1151.

https://doi.org/10.1182/blood.V126.23.1151.1151

Published: 2015

Journal Articles

Microarray Analysis of CD34+CXCR4+ and CD34+CXCR4- Cells Reveals Two Distinct Hematopoietic Stem/Progenitor Populations

Robert E Donahue, VMD, Ping Jin, Yu Tian, Robyn S Allen, Aylin Bonifacino, David Stroncek, MD

Blood (2010) 116 (21): 4798.

https://doi.org/10.1182/blood.V116.21.4798.4798

Published: 2010

Journal Articles

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

Leslie Kean, MD, PhD, Sharon Sen, Mark E Metzger, Aylin Bonifacino, Karnail Singh, Robert E Donahue, VMD

Blood (2010) 116 (21): 350.

https://doi.org/10.1182/blood.V116.21.350.350

Published: 2010

Journal Articles

Long-Term Reconstitution of Transduced Rhesus CD34+ Cells Mobilized by G-CSF and Plerixafor.

Naoya Uchida, MD, PhD, Aylin Bonifacino, Allen E Krouse, Sandra D Price, Ross M Fasano, MD, Gyorgy Csako, MD, Susan F Leitman, MD, Mark E Metzger, Matthew M Hsieh, MD, Joseph J Mattapallil, VMD, PhD, John F Tisdale, MD, Robert E Donahue, VMD

Blood (2010) 116 (21): 1449.

https://doi.org/10.1182/blood.V116.21.1449.1449

Published: 2010

Journal Articles

Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors

Derek A. Persons, James A. Allay, Aylin Bonifacino, Taihe Lu, Brian Agricola, Mark E. Metzger, Robert E. Donahue, Cynthia E. Dunbar, Brian P. Sorrentino

Blood (2004) 103 (3): 796–803.

https://doi.org/10.1182/blood-2003-05-1572

Published: 2004

NARROW

CD117 Antibody Conditioning and Multiplex Base Editing Enable Rapid and Robust Fetal Hemoglobin Reactivation in a Rhesus Autologous Transplantation Model

CD117 Antibody-Drug Conjugate Conditioning Allows Efficient Engraftment of Gene-Modified CD34+ Cells with Fertility Preservation in a Rhesus Gene Therapy Model

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque

Skewed HSC Clonal Output of T-Cells in an Aged Rhesus Macaque after CD3e-Immunotoxin Treatment

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Bone Marrow Characterization in Sickle Cell Disease: Inflammation and Stress Erythropoiesis Lead to Suboptimal CD34 Recovery Compared to Normal Volunteer Bone Marrow

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Microarray Analysis of CD34+CXCR4+ and CD34+CXCR4- Cells Reveals Two Distinct Hematopoietic Stem/Progenitor Populations

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

Long-Term Reconstitution of Transduced Rhesus CD34+ Cells Mobilized by G-CSF and Plerixafor.

Transient in vivo selection of transduced peripheral blood cells using antifolate drug selection in rhesus macaques that received transplants with hematopoietic stem cells expressing dihydrofolate reductase vectors

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American Society of Hematology

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ASH Publications

American Society of Hematology

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