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Lisa Olson
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Journal Articles

CD117 Antibody-Drug Conjugate Conditioning Allows Efficient Engraftment of Gene-Modified CD34+ Cells with Fertility Preservation in a Rhesus Gene Therapy Model

Naoya Uchida, Selami Demirci, Anh Le, Rebecca Chu, Xiong Liu, Ling Su, Xiaolin Wu, Allen Krouse, N Seth Linde, Aylin Bonifacino, So Gun Hong, Cynthia E. Dunbar, Leanne Lanieri, Anjali Bhat, Rahul Palchaudhuri, Bindu Bennet, Megan D. Hoban, Kirk Bertelsen, Lisa Olson, Robert Donahue, John F. Tisdale
Journal: Blood
Blood (2023) 142 (Supplement 1): 486.
https://doi.org/10.1182/blood-2023-177815
Published: 2023
Journal Articles

The Impact of CD45-Antibody-Drug Conjugate Conditioning on Clonal Dynamics and Immune Tolerance Post HSPC Transplantation in Rhesus Macaques

Taha Bartu Hayal, Chuanfeng Wu, Diana Abraham, Selami Demirci, Rahul Palchaudhuri, Leanne Lanieri, Anjali Bhat, Tiffany Tate, Zhuyan Guo, So Gun Hong, Lisa Olson, Robert Donahue, John F. Tisdale, Cynthia E. Dunbar
Journal: Blood
Blood (2023) 142 (Supplement 1): 3419.
https://doi.org/10.1182/blood-2023-182066
Published: 2023
Journal Articles

The Pharmacokinetic and Pharmacodynamic Characterization of Mgta-117, an Anti-CD117-Amanitin Antibody-Drug Conjugate for Targeted Conditioning Prior to Transplant, in Nonhuman Primates

Kirk Bertelsen, Leanne Lanieri, Rahul Palchaudhuri, Lisa Olson
Journal: Blood
Blood (2022) 140 (Supplement 1): 10227–10228.
https://doi.org/10.1182/blood-2022-159712
Published: 2022
Journal Articles

Targeted Deletion of Activated T Cells with a Single Dose of Anti-CD137-Antibody Drug Conjugate Protects Against Acute Gvhd (AGVHD) and Promotes Tolerogenic T Cell Reconstitution after Haplo-Identical Hematopoietic Stem Cell Transplantation (HSCT)

Ulrike Gerdemann, Jennifer Lane, Kyle Kimler, Leanne Lanieri, Lisa Olson, Leslie S. Kean, Victor Tkachev
Journal: Blood
Blood (2022) 140 (Supplement 1): 1568–1569.
https://doi.org/10.1182/blood-2022-166462
Published: 2022
Journal Articles

CD117 Antibody Drug Conjugate-Based Conditioning Allows for Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model

Naoya Uchida, Ulana Stasula, Malikiya Hinds, Paula Germino-Watnick, Allen E. Krouse, N Seth Linde, Aylin C. Bonifacino, Kellie Latimer, Prashant Bhattarai, Nicholas C. Yoder, Rahul Palchaudhuri, Qing Li, Kirk Bertelsen, Lisa Olson, Robert E. Donahue, John F. Tisdale
Journal: Blood
Blood (2021) 138 (Supplement 1): 560.
https://doi.org/10.1182/blood-2021-145524
Published: 2021
Journal Articles

Single Agent CD117-Targeted Antibody Drug Conjugate in Combination with Lymphodepleting Antibodies Enables Allogenic Hematopoietic Stem Cell Transplantation in Mice without Chemotherapy or Radiation

Leanne Lanieri, Tahirih Lamothe, Prashant Bhattarai, Rahul Palchaudhuri, Lisa Olson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1682.
https://doi.org/10.1182/blood-2021-147905
Published: 2021