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Allen E. Krouse
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Journal Articles

CD117 Antibody Conditioning and Multiplex Base Editing Enable Rapid and Robust Fetal Hemoglobin Reactivation in a Rhesus Autologous Transplantation Model

Selami Demirci, Nandini Mondal, Wayne Austin, Henna Butt, Evan London, Shruti Sathish, Kathy Zhang, Jeffrey Wong, Hugh Kromer, Alexander Harmon, Jeremy Decker, Anh Le, Khaled Essawi, Allen E Krouse, N Seth Linde, Aylin Bonifacino, Theresa Engels, Justin Golomb, So Gun Hong, Naoya Uchida, Nicole Gaudelli, Adam J. Hartigan, Charlotte F McDonagh, S Haihua Chu, Robert E Donahue, John Tisdale
Journal: Blood
Blood (2024) 144 (Supplement 1): 516.
https://doi.org/10.1182/blood-2024-204403
Published: 2024
Journal Articles

CD117 Antibody Drug Conjugate-Based Conditioning Allows for Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model

Naoya Uchida, Ulana Stasula, Malikiya Hinds, Paula Germino-Watnick, Allen E. Krouse, N Seth Linde, Aylin C. Bonifacino, Kellie Latimer, Prashant Bhattarai, Nicholas C. Yoder, Rahul Palchaudhuri, Qing Li, Kirk Bertelsen, Lisa Olson, Robert E. Donahue, John F. Tisdale
Journal: Blood
Blood (2021) 138 (Supplement 1): 560.
https://doi.org/10.1182/blood-2021-145524
Published: 2021
Journal Articles

Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing

Selami Demirci, PhD, Jing Zeng, MD, Yuxuan Wu, PhD, Naoya Uchida, MD, Jackson Gamer, Morgan Yapundich, Claire Drysdale, Aylin C. Bonifacino, Allen E. Krouse, Nathaniel S. Linde, Robert E. Donahue, VMD, Anne H. Shen, Juan J. Haro-Mora, PhD, Alexis Leonard, MD, Tina Nassehi, Kevin Luk, Scot A. Wolfe, Cicera R. Lazzarotto, Shengdar Q. Tsai, PhD, Mitchell J. Weiss, MD, PhD, Daniel E. Bauer, MD PhD, John F. Tisdale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4632.
https://doi.org/10.1182/blood-2019-129394
Published: 2019
Journal Articles

Development of a New Generation, Forward-Oriented Therapeutic Vector for Hemoglobin Disorders

Naoya Uchida, MD PhD, Matthew M. Hsieh, MD, Aylin C Bonifacino, Allen E Krouse, Mark E Metzger, Robert E Donahue, John F. Tisdale, MD
Journal: Blood
Blood (2016) 128 (22): 1172.
https://doi.org/10.1182/blood.V128.22.1172.1172
Published: 2016
Journal Articles

Discordance in lymphoid tissue recovery following stem cell transplantation in rhesus macaques: an in vivo imaging study

Robert E. Donahue, Sharat Srinivasula, Naoya Uchida, Insook Kim, Alexis St. Claire, Gorka Duralde, Paula DeGrange, Marisa St. Claire, Richard C. Reba, Aylin C. Bonifacino, Allen E. Krouse, Mark E. Metzger, Chang H. Paik, H. Clifford Lane, John F. Tisdale, Michele Di Mascio
Journal: Blood
Blood (2015) 126 (24): 2632–2641.
https://doi.org/10.1182/blood-2015-07-657346
Published: 2015
Includes: Supplemental data
Journal Articles

Clonal Tracking of the Geographic Distribution of Hematopoiesis in Nonhuman Primates Provides New Insights into HSPC Migration and Differentiation

Chuanfeng Wu, PhD, Samson J Koelle, Brian Li, Diego Espinoza, Rong Lu, Allen E Krouse, Mark Metzger, Robert Donahue, VMD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2015) 126 (23): 241.
https://doi.org/10.1182/blood.V126.23.241.241
Published: 2015
Journal Articles

Evaluation of CD4+ Cell Recovery in Vivo Using Single Photon Emission Tomography (SPECT) in Real Time Following CD34+ Cell Transplantation in Rhesus Macaques

Robert E. Donahue, Sharat Srinivasula, Naoya Uchida, MD PhD, Insook Kim, Gorka Duralde, Paula DeGrange, Marisa St. Claire, Richard C. Reba, Aylin C. Bonifacino, Allen E. Krouse, Mark E. Metzger, Chang H. Paik, H. Clifford Lane, John F. Tisdale, MD, Michele Di Mascio
Journal: Blood
Blood (2014) 124 (21): 1105.
https://doi.org/10.1182/blood.V124.21.1105.1105
Published: 2014
Journal Articles

Discordance Between Peripheral Blood and Tissue CD4+ Lymphocyte Reconstitution In Rhesus Monkeys Following Autologous Hematopoietic CD34+ Cell Transplantation: An In Vivo imaging Study

Robert E. Donahue, Sharat Srinivasula, Naoya Uchida, MD, PhD, Insook Kim, Gorka Duralde, Paula DeGrange, Marisa St. Claire, Richard C. Reba, Aylin C. Bonifacino, Allen E. Krouse, Mark E. Metzger, Chang H. Paik, H. Clifford Lane, John F. Tisdale, MD, Michele Di Mascio
Journal: Blood
Blood (2013) 122 (21): 2019.
https://doi.org/10.1182/blood.V122.21.2019.2019
Published: 2013
Journal Articles

The Unique Ontogeny Of Natural Killer Cells As Revealed By Genetic Barcoding In The Nonhuman Primate Model

Chuanfeng Wu, PhD, Jan K. Davidson-Moncada, MD, PhD, Rong Lu, PhD, Brian Li, Allen E. Krouse, Mark E. Metzger, Robert E. Donahue, Irving L. Weissman, MD, Richard Childs, MD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2013) 122 (21): 15.
https://doi.org/10.1182/blood.V122.21.15.15
Published: 2013
Journal Articles

TRIM5α Variation Affects Lentiviral Transduction Efficiency for Long-Term Hematopoietic Repopulating Cells in a Rhesus Stem Cell Transplantation Model

Naoya Uchida, Matthew M. Hsieh, MD, Aylin C. Bonifacino, Sandra D. Price, Allen E. Krouse, Mark E. Metzger, Robert E. Donahue, John F. Tisdale
Journal: Blood
Blood (2011) 118 (21): 2056.
https://doi.org/10.1182/blood.V118.21.2056.2056
Published: 2011
Journal Articles

High Transgene Expression Rates After Extended Follow up Among Rhesus Macaque Recipients of Autologous Hematopoietic Stem Cells Transduced with a Modified HIV1-Based Lentiviral Vector

Naoya Uchida, Phillip W. Hargrove, M.S., Coen J. Lap, MD, Oswald Phang, Jr., Aylin C. Bonifacino, Allen E. Krouse, Mark E. Metzger, Anh-Dao Nguyen, Matthew M. Hsieh, MD, Tyra G. Wolfsberg, Robert E. Donahue, Derek A. Persons, MD, PhD, John F. Tisdale
Journal: Blood
Blood (2011) 118 (21): 3118.
https://doi.org/10.1182/blood.V118.21.3118.3118
Published: 2011
Journal Articles

Long-Term Reconstitution of Transduced Rhesus CD34+ Cells Mobilized by G-CSF and Plerixafor.

Naoya Uchida, MD, PhD, Aylin Bonifacino, Allen E Krouse, Sandra D Price, Ross M Fasano, MD, Gyorgy Csako, MD, Susan F Leitman, MD, Mark E Metzger, Matthew M Hsieh, MD, Joseph J Mattapallil, VMD, PhD, John F Tisdale, MD, Robert E Donahue, VMD
Journal: Blood
Blood (2010) 116 (21): 1449.
https://doi.org/10.1182/blood.V116.21.1449.1449
Published: 2010
Journal Articles

Suicide Gene (HSVtk) Ablation of Hematopoietic Stem Cells and Their Progeny In the Rhesus Macaque Model: An Approach to Deletion of Dangerous Clones.

Cecilia Barese, MD, PhD, Connor King, Stephanie Sellers, Allen E Krouse, Mark E Metzger, Catia Traversari, MD, Claudio Bordignon, MD, Steven M. Kornblau, MD, Frank Marini, III, PhD, Robert E Donahue, VMD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2010) 116 (21): 3759.
https://doi.org/10.1182/blood.V116.21.3759.3759
Published: 2010
Journal Articles

A Modified HIV1-Based Lentiviral Vector Can Transduce Rhesus Hematopoietic Repopulating Cells as Efficiently as An SIV Vector in An Autologous Transplantation Model.

Naoya Uchida, MD, PhD, Phillip W Hargrove, M.S., Kareem Washington, PhD, Coen J. Lap, MD, Matthew M. Hsieh, MD, Aylin C. Bonifacino, Sandra D. Price, Allen E. Krouse, Mark E. Metzger, Robert E. Donahue, VMD, Derek Persons, MD, PhD, John F. Tisdale, MD
Journal: Blood
Blood (2009) 114 (22): 692.
https://doi.org/10.1182/blood.V114.22.692.692
Published: 2009
Journal Articles

Development of An HIV1-Based Lentiviral Vector Able to Transduce Both Human and Rhesus Blood Cells.

Naoya Uchida, MD, Kareem Washington, PhD, Jun Hayakawa, MD, PhD, Matthew Hsieh, MD, Aylin C. Bonifacino, Allen E. Krouse, Mark E. Metzger, Robert E. Donahue, VMD, John F. Tisdale, MD
Journal: Blood
Blood (2008) 112 (11): 2353.
https://doi.org/10.1182/blood.V112.11.2353.2353
Published: 2008
Journal Articles

Distinctive Integration Profile of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-Term Repopulating Cells.

Jingqiong Hu, MD, Theotonius Gomes, Andrea Ferris, PhD, Gabriel Renaud, PhD, Paul C. Hendrie, PhD, Allen E. Krouse, VD, Robert E. Donahue, VD, Tyra G. Wolfsberg, PhD, Stephen H. Hughes, PhD, David W. Russell, MD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2007) 110 (11): 198.
https://doi.org/10.1182/blood.V110.11.198.198
Published: 2007