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John Tisdale
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Journal Articles

An Update on Lovotibeglogene Autotemcel (Lovo-cel) Clinical Trials for Sickle Cell Disease (SCD) and Analysis of Early Predictors of Response to Lovo-Cel

Stacey Rifkin-Zenenberg, Julie Kanter, Melissa A. Kinney, Janet L. Kwiatkowski, Robert S. Nickel, Mark C. Walters, Suhag Parikh, Alexis Thompson, Anil P. George, Markus Mapara, Paul L. Martin, Anjulika Chawla, Ankit Lodaya, Lin Pan, Emily Sheldon-Waniga, Francis J. Pierciey, Jr., John Tisdale, Ashish O. Gupta
Journal: Blood
Blood (2024) 144 (Supplement 1): 511.
https://doi.org/10.1182/blood-2024-199743
Published: 2024
Journal Articles

MLL1 Complex Is a Critical Regulator of Fetal Hemoglobin Repression

Yufen Han, Kartik Roy, Kristbjorn Gudmundsson, Bjorg Gudmundsdottir, John Tisdale, Yang Du
Journal: Blood
Blood (2024) 144 (Supplement 1): 411.
https://doi.org/10.1182/blood-2024-199305
Published: 2024
Journal Articles

Motixafortide for Hematopoietic Stem and Progenitor Cell Mobilization and Collection in Sickle Cell Disease

Alexis Kristine Leonard, Akshay Sharma, Yogindra Persaud, Parul Rai, Darla Pickett, Renee Massey, Neha Das Gupta, Subodh Selukar, Salem M. Akel, Leigh Poston, Yan Zheng, Ella Sorani, Irit Gliko Kabir, Mitchell J Weiss, Stephen Gottschalk, Julie Kanter, Matthew Hsieh, John Tisdale
Journal: Blood
Blood (2024) 144 (Supplement 1): 2100.1.
https://doi.org/10.1182/blood-2024-200330
Published: 2024
Journal Articles

CD117 Antibody Conditioning and Multiplex Base Editing Enable Rapid and Robust Fetal Hemoglobin Reactivation in a Rhesus Autologous Transplantation Model

Selami Demirci, Nandini Mondal, Wayne Austin, Henna Butt, Evan London, Shruti Sathish, Kathy Zhang, Jeffrey Wong, Hugh Kromer, Alexander Harmon, Jeremy Decker, Anh Le, Khaled Essawi, Allen E Krouse, N Seth Linde, Aylin Bonifacino, Theresa Engels, Justin Golomb, So Gun Hong, Naoya Uchida, Nicole Gaudelli, Adam J. Hartigan, Charlotte F McDonagh, S Haihua Chu, Robert E Donahue, John Tisdale
Journal: Blood
Blood (2024) 144 (Supplement 1): 516.
https://doi.org/10.1182/blood-2024-204403
Published: 2024
Journal Articles

Adding CD117 Antibody to Alemtuzumab, Low Dose Total Body Irradiation (TBI), and Sirolimus for Matched Related Donor (MRD) Hematopoietic Cell Transplant (HCT) in Sickle Cell Disease (SCD): Initial Results

Matthew Hsieh, Priscilla Pollack, Elizabeth Harvey, Triscia Martin, Neal Jeffries, Wendy W Pang, John Tisdale
Journal: Blood
Blood (2024) 144 (Supplement 1): 1141.
https://doi.org/10.1182/blood-2024-200214
Published: 2024
Journal Articles

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Thiyagaraj Mayuranathan, Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Guolian Kang, Cicera Lazzarotto, Yichao Li, Rachel Levine, Erin Dempsey, Shaina N. Porter, Phillip A Doerfler, Jingjing Zhang, Yoonjeong Jang, Senthil Bhoopalan, Nikitha Nimmagadda, Akshay Sharma, John Tisdale, Shondra Miller, Yong Cheng, Shengdar Tsai, Mitchell J. Weiss, David R. Liu, Jonathan S Yen
Journal: Blood
Blood (2022) 140 (Supplement 1): 7784–7785.
https://doi.org/10.1182/blood-2022-162639
Published: 2022
Journal Articles

Phenotypic Screening of the Reframe Drug Repurposing Library to Discover New Drugs for Treating Sickle Cell Disease

William A. Eaton, Belhu Metaferia, Troy Cellmer, Emily B. Dunkelberger, Quan Li, Eric R. Henry, James Hofrichter, Dwayne Staton, Matthew M. Hsieh, Anna Conrey, John Tisdale, Arnab K. Chatterjee, Swee Lay Thein
Journal: Blood
Blood (2022) 140 (Supplement 1): 11089–11090.
https://doi.org/10.1182/blood-2022-159634
Published: 2022
Journal Articles

A Phase 2, Open-Label Study to Evaluate the Efficacy and Safety of Mgta-145 in Combination with Plerixafor for the Mobilization of Hematopoietic Stem Cells in Patients with Sickle Cell Anemia

Akshay Sharma, John P Manis, David G. Justus, David A. Williams, Sergey Efuni, Ji Hyun Lee, Erin Conlin, Shawn Rose, Jeffrey Humphrey, Kirk Bertelsen, Nicole Henry, June Li, Donald Pardy, David Santos, Christian Zdybowicz, Alexis Leonard, John Tisdale
Journal: Blood
Blood (2022) 140 (Supplement 1): 8263–8264.
https://doi.org/10.1182/blood-2022-159728
Published: 2022
Journal Articles

A Practical Erythroid Assay in Humanized Xenograft Mouse Model

Jun Hayakawa, MD, PhD, Matthew Hsieh, MD, Naoya Uchida, MD, Kareem Washington, PhD, Oswald Phang, David Eric Anderson, PhD, John Tisdale, MD
Journal: Blood
Blood (2008) 112 (11): 2446.
https://doi.org/10.1182/blood.V112.11.2446.2446
Published: 2008
Journal Articles

Comparative Results of Gene Therapy for Adenosine Deaminase Deficiency with or without PEG-ADA Withdrawal and Myelosuppressive Chemotherapy.

Robert Sokolic, MD, Greg Podsakoff, MD, Linda Muul, PhD, Barbara Engel, MD, Jayashree Jagadeesh, BS, Elizabeth Garabedian, RN, MSLS, Denise Carbonaro, Laura Tuschong, BS, Joanna Ireland, Michael Hershfield, MD, John Tisdale, MD, Cynthia Dunbar, MD, Alan Wayne, MD, Donald Kohn, MD, Fabio Candotti, MD
Journal: Blood
Blood (2007) 110 (11): 501.
https://doi.org/10.1182/blood.V110.11.501.501
Published: 2007
Journal Articles

A Pilot Study Evaluating the CD34+ Cell Mobilizing Activity and Adverse Events Associated with Escalating Doses of AMD3100 in Healthy Volunteers.

Steven J. Lemery, MD, Matthew M. Hsieh, MD, Aleah Smith, Sheila Rao, Hanh M. Khuu, Donohue Theresa, PA, Jennifer M. Karpovich, NP, Lisa Cook, RN, Rose Goodwin, RN, Carol Boss, MPH, Gary Calandra, Nancy Geller, PhD, John Tisdale, MD, Richard Childs, MD
Journal: Blood
Blood (2007) 110 (11): 3278.
https://doi.org/10.1182/blood.V110.11.3278.3278
Published: 2007
Journal Articles

Genetic Correction of Sickle Cell Disease by Co-Regulated γ-Globin Transgene Expression and ßS Interference.

Selda Samakoglu, Yelena Usachenko, Tulin Budak-Alpdogan, Santina Acuto, Rosalba DiMarzo, Aurelio Maggio, John Tisdale, Isabelle Riviere, Michel Sadelain
Journal: Blood
Blood (2005) 106 (11): 1280.
https://doi.org/10.1182/blood.V106.11.1280.1280
Published: 2005
Journal Articles

Intracellular interferon-γ in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia

Clinical Trials & Observations
Elaine Sloand, Sonnie Kim, Jaroslaw P. Maciejewski, John Tisdale, Dean Follmann, Neal S. Young
Journal: Blood
Blood (2002) 100 (4): 1185–1191.
https://doi.org/10.1182/blood-2002-01-0035
Published: 2002