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Journal Articles

The Amyloidogenic Transthyretin V122I Variant Increase Severity of Cardiac Phenotype and Mortality in Sickle Cell Disease

Haiou Li, Xunde Wang, Nancy Asomaning, Anna Conrey, Britney Kruah, Kylie Haymaker, Colin O. Wu, Vandana Sachdev, Swee Lay Thein

Blood (2024) 144 (Supplement 1): 800.

https://doi.org/10.1182/blood-2024-197909

Published: 2024

Journal Articles

A Machine Learning-Based Workflow for Predicting Transplant Outcome in Patients with Sickle Cell Disease

Haiou Li, Vandana Sachdev, Xin Tian, My-Le Nguyen, Matthew Hsieh, Courtney D. Fitzhugh, Emily Limerick, Wynona Coles, Nancy Asomaning, Anna Conrey, Colin O. Wu, Swee Lay Thein

Blood (2024) 144 (Supplement 1): 177.

https://doi.org/10.1182/blood-2024-194897

Published: 2024

Journal Articles

Duffy Status and Hydroxyurea Dosing in Adult Patients with Sickle Cell Disease: A Potential for Iatrogenic Harm?

Eileen Ryan, Xunde Wang, Haiou Li, Anna Conrey, Swee Lay Thein

Blood (2024) 144 (Supplement 1): 2513.

https://doi.org/10.1182/blood-2024-203640

Published: 2024

Journal Articles

A Phase 1 Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects with Stable Sickle Cell Disease: Trial in Progress

Anna Conrey, Dianna Lovins, Rivers Kimberly, Yuan Yee Lee, Kang Le, Britney Kruah, Xunde Wang, Belhu Metaferia, Philip S. Low, Neal Jeffries, William A Eaton, Swee Lay Thein

Blood (2024) 144 (Supplement 1): 1143.1.

https://doi.org/10.1182/blood-2024-193267

Published: 2024

Journal Articles

Mitapivat-Induced Improvements in RBC Deformability and Membrane Integrity in Patients with Sickle Cell Disease Are Sustained during Extended Therapy

Xunde Wang, Yechan Cho, Nancy Asomaning, Maureen Lundt, Anna Conrey, Britney Kruah, Amber M Yates, Megan Wind-Rotolo, Haiou Li, Kang Le, Swee Lay Thein

Blood (2024) 144 (Supplement 1): 2491.

https://doi.org/10.1182/blood-2024-206051

Published: 2024

Journal Articles

8-Oxoguanine DNA Glycosylase 1 Recruits Transcription Factor STAT1 to Promote the Inflammatory Responses in Sickle Cell Disease

Kang Le, Zenaide Quezado, Haiou Li, Sayuri Kamimura, Meghann L. Smith, Yuki Tahara, Yujeong Lee, Anna Conrey, Josie Schultz, Thorkell Andresson, Eric T Kool, Swee Lay Thein

Blood (2024) 144 (Supplement 1): 2490.

https://doi.org/10.1182/blood-2024-201619

Published: 2024

Journal Articles

Long-Term Safety and Efficacy of Mitapivat, an Oral Pyruvate Kinase Activator, in Adults with Sickle Cell Disease: Extension of a Phase 1 Dose Escalation Study

Anna Conrey, Ingrid Frey, Nancy Asomaning, Ruth Pierre Charles, Dina Parekh, Julia Xu, Kang Le, Britney Kruah, Quan Li, Emily Dunkelberger, Troy Cellmer, Amber M Yates, Megan Wind-Rotolo, Neal Jeffries, William A Eaton, Swee Lay Thein

Blood (2023) 142 (Supplement 1): 273.

https://doi.org/10.1182/blood-2023-180165

Published: 2023

Journal Articles

Evaluation of Red Cell Deformability in Sickle Cell Disease Patients, Sickle Cell Carriers, and Healthy Controls Using Lorrca-Derived Parameters

Nancy Asomaning, Xunde Wang, Maureen Lundt, Britney Kruah, Mai Hill, Anna Conrey, Ruth Pierre Charles, Ingrid Frey, Megan Wind-Rotolo, Chris Huston, Neal Jeffries, Swee Lay Thein

Blood (2023) 142 (Supplement 1): 5262.

https://doi.org/10.1182/blood-2023-184834

Published: 2023

Journal Articles

Exploring Near Infrared Spectroscopy As a Tool for Monitoring Tissue Hemodynamics for Patients with Sickle Cell Disease

Golnar Mostashari, Timothy Quang, Helen E Parker, Mai Hill, Dina Parekh, Andrew Keel, Anna Conrey, Swee Lay Thein, Bruce J Tromberg

Blood (2023) 142 (Supplement 1): 3862.

https://doi.org/10.1182/blood-2023-174241

Published: 2023

Journal Articles

Longitudinal Characterization of Hemodynamic Changes with Multimodal Optical Techniques in Patients with Sickle Cell Disease Treated with Mitapivat

Timothy Quang, Ingrid Frey, Julia Xu, Golnar Mostashari, Anna Conrey, Dina S. Parekh, Ruth Pierre Charles, Brian Hill, Swee Lay Thein, Bruce J Tromberg

Blood (2023) 142 (Supplement 1): 2492.

https://doi.org/10.1182/blood-2023-174227

Published: 2023

Journal Articles

8-Oxoguanine DNA Glycosylase 1 Inhibition Suppresses Inflammatory Responses in Sickle Cell Disease

Kang Le, Zenaide Quezado, Sayuri Kamimura, Meghann L. Smith, Yuki Tahara, Yujeong Lee, Laxminath Tumburu, Anna Conrey, Eric T Kool, Swee Lay Thein

Blood (2023) 142 (Supplement 1): 2482.

https://doi.org/10.1182/blood-2023-182157

Published: 2023

Journal Articles

Effects of Isoquercetin on Plasma Protein Disulfide Isomerase Activity and Extracellular Vesicle Tissue Factor Antigen/Activity in Sickle Cell Disease

Bindu Parachalil Gopalan, Maria A.A. Lizarralde-Iragorri, Anna Conrey, Mai Hill, Brenda Merriweather, Jennifer Brooks, Ruth Pierre Charles, Eveline Gwaabe, Rafael Villasmil, Neal Jeffries, Arun S. Shet

Blood (2022) 140 (Supplement 1): 8272–8273.

https://doi.org/10.1182/blood-2022-166982

Published: 2022

Journal Articles

Targeting Thrombophilia in Sickle Cell Disease with Isoquercetin: Results of a Fixed Dose, Single Center, Phase II Randomized Clinical Trial

Maria A. Lizarralde-Iragorri, Bindu Parachalil Gopalan, Brenda Merriweather, Jennifer Brooks, Mai Hill, Anna Conrey, Ruth Pierre Charles, Eveline Gwaabe, Neal Jeffries, Arun S. Shet

Blood (2022) 140 (Supplement 1): 8270–8271.

https://doi.org/10.1182/blood-2022-166518

Published: 2022

Journal Articles

Phenotypic Screening of the Reframe Drug Repurposing Library to Discover New Drugs for Treating Sickle Cell Disease

William A. Eaton, Belhu Metaferia, Troy Cellmer, Emily B. Dunkelberger, Quan Li, Eric R. Henry, James Hofrichter, Dwayne Staton, Matthew M. Hsieh, Anna Conrey, John Tisdale, Arnab K. Chatterjee, Swee Lay Thein

Blood (2022) 140 (Supplement 1): 11089–11090.

https://doi.org/10.1182/blood-2022-159634

Published: 2022

Journal Articles

Activating Pyruvate Kinase Improves Red Blood Cell Integrity By Reducing Band3 Tyrosine Phosphorylation

Kang Le, Xunde Wang, Maureen Lundt, Anna Conrey, Ingrid Frey, Silvia Giannini, Penelope A. Kosinski, John A. Hausman, Philip S. Low, Neal Jeffries, Swee Lay Thein

Blood (2022) 140 (Supplement 1): 5395–5396.

https://doi.org/10.1182/blood-2022-160378

Published: 2022

Journal Articles

Feasibility of Near-Infrared Spectroscopy for Monitoring Hemodynamic Changes in Patients with Sickle Cell Disease Treated with Mitapivat

Timothy Quang, Julia Z Xu, Ingrid Frey, Kathryn Jaroszynski, Elise M. Berning, Anna Conrey, Ruth Pierre Charles, Brian Y Hill, Neal Jeffries, Swee Lay Thein, Bruce J. Tromberg

Blood (2022) 140 (Supplement 1): 2526–2527.

https://doi.org/10.1182/blood-2022-159559

Published: 2022

Journal Articles

The Pyruvate Kinase Activator Mitapivat Improves Red Blood Cell Deformability and Sickling Kinetics in Adult Patients with Sickle Cell Disease

Maureen Lundt, Nancy Asomaning, Ingrid Frey, Xunde Wang, Anna Conrey, Julia Z Xu, Quan Li, Emily B Dunkelberger, Neal Jeffries, William Eaton, Swee Lay Thein

Blood (2022) 140 (Supplement 1): 2508–2509.

https://doi.org/10.1182/blood-2022-170010

Published: 2022

Journal Articles

A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease

Blood (2022) 140 (19): 2053–2062.

https://doi.org/10.1182/blood.2022015403

Published: 2022

Includes: Supplemental data

Journal Articles

Effects of Quercetin on Neutrophil Extracellular Trap Formation in Sickle Cell Disease

Bindu Parachalil Gopalan, Brenda Merriweather, Anna Conrey, Ankit Saxena, Evi X. Stavrou, Arun S Shet

Blood (2021) 138 (Supplement 1): 2024.

https://doi.org/10.1182/blood-2021-153450

Published: 2021

Journal Articles

Effects of Flavonoid Quercetin on Thrombo-Inflammatory Processes in Patients with Sickle Cell Disease

Maria A. Lizarralde, Brenda Merriweather, Anna Conrey, Ankit Saxena, Arun S Shet

Blood (2021) 138 (Supplement 1): 2020.

https://doi.org/10.1182/blood-2021-148601

Published: 2021

NARROW

The Amyloidogenic Transthyretin V122I Variant Increase Severity of Cardiac Phenotype and Mortality in Sickle Cell Disease

A Machine Learning-Based Workflow for Predicting Transplant Outcome in Patients with Sickle Cell Disease

Duffy Status and Hydroxyurea Dosing in Adult Patients with Sickle Cell Disease: A Potential for Iatrogenic Harm?

A Phase 1 Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects with Stable Sickle Cell Disease: Trial in Progress

Mitapivat-Induced Improvements in RBC Deformability and Membrane Integrity in Patients with Sickle Cell Disease Are Sustained during Extended Therapy

8-Oxoguanine DNA Glycosylase 1 Recruits Transcription Factor STAT1 to Promote the Inflammatory Responses in Sickle Cell Disease

Long-Term Safety and Efficacy of Mitapivat, an Oral Pyruvate Kinase Activator, in Adults with Sickle Cell Disease: Extension of a Phase 1 Dose Escalation Study

Evaluation of Red Cell Deformability in Sickle Cell Disease Patients, Sickle Cell Carriers, and Healthy Controls Using Lorrca-Derived Parameters

Exploring Near Infrared Spectroscopy As a Tool for Monitoring Tissue Hemodynamics for Patients with Sickle Cell Disease

Longitudinal Characterization of Hemodynamic Changes with Multimodal Optical Techniques in Patients with Sickle Cell Disease Treated with Mitapivat

8-Oxoguanine DNA Glycosylase 1 Inhibition Suppresses Inflammatory Responses in Sickle Cell Disease

Effects of Isoquercetin on Plasma Protein Disulfide Isomerase Activity and Extracellular Vesicle Tissue Factor Antigen/Activity in Sickle Cell Disease

Targeting Thrombophilia in Sickle Cell Disease with Isoquercetin: Results of a Fixed Dose, Single Center, Phase II Randomized Clinical Trial

Phenotypic Screening of the Reframe Drug Repurposing Library to Discover New Drugs for Treating Sickle Cell Disease

Activating Pyruvate Kinase Improves Red Blood Cell Integrity By Reducing Band3 Tyrosine Phosphorylation

Feasibility of Near-Infrared Spectroscopy for Monitoring Hemodynamic Changes in Patients with Sickle Cell Disease Treated with Mitapivat

The Pyruvate Kinase Activator Mitapivat Improves Red Blood Cell Deformability and Sickling Kinetics in Adult Patients with Sickle Cell Disease

A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease

Effects of Quercetin on Neutrophil Extracellular Trap Formation in Sickle Cell Disease

Effects of Flavonoid Quercetin on Thrombo-Inflammatory Processes in Patients with Sickle Cell Disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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