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Journal Articles

High Dose Plerixafor Is Safe and Mobilizes Higher Numbers of CD34+ Cells Compared with Standard Dose Plerixafor

Jeremy M Pantin, MB.BS., Xin Tian, Ph.D., Matthew M. Hsieh, MD, Lisa Cook, RN, BSN, Theresa Donohue, MHS, PA-C, Elena Cho, RN MSN, Aleah Smith, Robert Reger, Thomas Trischman, PhD, Hanh Khuu, MD, Richard Childs, MD

Blood (2012) 120 (21): 585.

https://doi.org/10.1182/blood.V120.21.585.585

Published: 2012

Journal Articles

Optimizing Lentiviral Transduction of Human Natural Killer Cells

Su Su, MD, PhD, Dawn M Betters, Ph.D, Muthalagu Ramanathan, MD, Keyvan Keyvanfar, BS, Aleah Smith, Xingmin Feng, PhD, Elissa Furutani, Mattias Carlsten, MD Ph.D, Andreas Lundqvist, PhD, Richard Childs, MD

Blood (2011) 118 (21): 4714.

https://doi.org/10.1182/blood.V118.21.4714.4714

Published: 2011

Journal Articles

HLA Alloantibody Persistence and De Novo Production of HLA Alloantibodies of Donor Origin Following Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation.

Ross M Fasano, MD, Sharon Adams, Aleah Smith, Theresa Donohue, MS, PA-C, Charles D. Bolan, Jr., MD, Kyoko Sugimoto, MD, PhD, Willy A. Flegel, MD, Richard Childs, MD

Blood (2010) 116 (21): 1109.

https://doi.org/10.1182/blood.V116.21.1109.1109

Published: 2010

Journal Articles

Adoptive Transfer of Escalating Doses of Ex Vivo Expanded Autologous Natural Killer (NK) Cells In Patients with Advanced Malignancies Following Bortezomib Treatment to Sensitize to NK-TRAIL Cytotoxicity

Aleah Smith, Hahn Khuu, MD, Dawn M Betters, RN, Lisa Cook, RN, BSN, Catalina Ramos, RN, BSN, Sophia Grasmeder, RN, BSN, OCN, Maria Berg, Rebecca Lopez, PhD, Su Su, MD, PhD, Vicki Fellowes, MT, David Stroncek, MD, Jeremy Pantin, MD, Sumi Vasu, MD, Theresa Donohue, MHS, PA-C, Keyvan Keyvanfar, BS, Richard Childs, MD

Blood (2010) 116 (21): 4296.

https://doi.org/10.1182/blood.V116.21.4296.4296

Published: 2010

Journal Articles

siRNA Inactivation of the Inhibitory Receptor NKG2A Augments the Anti-Tumor Effects of Adoptively Transferred NK Cells In Tumor-Bearing Hosts

Elissa Furutani, Su Su, MD, PhD, Aleah Smith, Maria Berg, Richard Childs, MD

Blood (2010) 116 (21): 1015.

https://doi.org/10.1182/blood.V116.21.1015.1015

Published: 2010

Journal Articles

In Vitro Assessment of Tolerance and Rejection Occurring After Co-Transplantation of Allogeneic Umbilical Cord Blood and Haploidentical CD34+ Cells as Treatment for Severe Aplastic Anemia

Nicole J. Gormley, MD, Aleah Smith, Maria Berg, Lisa Cook, RN, BSN, Catalina Ramos, RN, Sophia Grasmeder, RN, BSN, OCN, Theresa Donohue, MHS, PA-C, Richard Childs, MD

Blood (2010) 116 (21): 2352.

https://doi.org/10.1182/blood.V116.21.2352.2352

Published: 2010

Journal Articles

Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells

Andreas Lundqvist, Hisayuki Yokoyama, Aleah Smith, Maria Berg, Richard Childs

Blood (2009) 113 (24): 6120–6127.

https://doi.org/10.1182/blood-2008-11-190421

Published: 2009

Journal Articles

Lentiviral Transduction of Ex Vivo Expanded Natural Killer Cells with a CD19 Chimeric Antigen Receptor Induces Cytotoxicity against Resistant B Cell Malignancies

Muthalagu Ramanathan, Su Su, Andreas Lundqvist, Maria Berg, Aleah Smith, Rebecca Lopez, Ann Williams, Erkut Bahceci, J. Philip McCoy, Laurent Boissel, Hans-Georg Klingemann, Richard Childs

Blood (2008) 112 (11): 3540.

https://doi.org/10.1182/blood.V112.11.3540.3540

Published: 2008

Journal Articles

A Rhesus Macaque Model to Optimize Adoptive NK Cell Therapy

Rebecca Lopez, Andreas Lundqvist, Stephanie Sellers, Maria Berg, Muthalagu Ramanathan, Sumithira Vasu, Aleah Smith, Cynthia E. Dunbar, Richard W. Childs, MD

Blood (2008) 112 (11): 3905.

https://doi.org/10.1182/blood.V112.11.3905.3905

Published: 2008

Journal Articles

Adoptively-Infused NK Cells Maintain Their Antitumor Effects in Vivo in the Presence of CyclosporineA (CSA)

Hisayuki Yokoyama, Andreas Lundqvist, Maria Berg, Muthalagu Ramanathan, Rebecca Lopez, Aleah Smith, Nicole Gormley, Su Su, J. Phillip McCoy, Richard W. Childs, MD

Blood (2008) 112 (11): 2563.

https://doi.org/10.1182/blood.V112.11.2563.2563

Published: 2008

Journal Articles

Bortezomib Enhances the Antitumor Activity of Adoptively Infused Natural Killer Cells In Vivo: A Novel Approach To Override KIR-Mediated Inhibition of NK Cell Cytotoxicity.

Andreas Lundqvist, PhD, Sheila Rao, BS, Aleah Smith, BS, Maria Berg, BS, Su Su, PhD, Hisayuki Yokoyama, PhD, Shivani Srivastava, MD, Richard Childs, MD

Blood (2007) 110 (11): 1786.

https://doi.org/10.1182/blood.V110.11.1786.1786

Published: 2007

Journal Articles

The Proteasome Inhibitor Bortezomib Simultaneously Enhances NK Cell Tumor Cytotoxicity While Paradoxically Reducing Antigen Specific T-Cell Tumor Cytotoxicity.

Andreas Lundqvist, PhD, Sheila Rao, BS, Maria Berg, BS, Aleah Smith, BS, Su Su, PhD, Hisayuki Yokoyama, PhD, Shivani Srivastava, MD, Richard Childs, MD

Blood (2007) 110 (11): 1789.

https://doi.org/10.1182/blood.V110.11.1789.1789

Published: 2007

Journal Articles

Cyclosporine A (CSA) Significantly Reduces the Cytotoxic Effects of In Vitro Expanded NK Cells: Implications for Adoptive NK Cell Therapy in the Setting of Allogeneic Hematopoietic Stem Cell Transplantation (HCT).

Hisayuki Yokoyama, MD, PhD, Maria Berg, Andreas Lundqvist, PhD, J. Philip McCoy, PhD, Shivani Srivastava, MD, Aleah Smith, Richard Childs, MD

Blood (2007) 110 (11): 4899.

https://doi.org/10.1182/blood.V110.11.4899.4899

Published: 2007

Journal Articles

Reduced Incidence of Acute Graft Versus Host Disease (GVHD) and Transplant-Related Mortality (TRM) with the Addition of Short-Course Mini-Dose Methotrexate (MTX) to Cyclosporine (CSA) as GVHD Prophylaxis Following Nonmyeloablative Hematopoietic Stem Cell Transplantation (NST).

Ramaprasad Srinivasan, Haley Hedlin, Rose Goodwin, Aleah Smith, Catalina Ramos, Lisa Cook, Charles Bolan, Hisayuki Yokoyama, Shivani Srivastava, Jennifer Karpovich, Teresa Donohue, John Barrett, Nancy Geller, Richard Childs

Blood (2007) 110 (11): 2990.

https://doi.org/10.1182/blood.V110.11.2990.2990

Published: 2007

Journal Articles

A Pilot Study Evaluating the CD34+ Cell Mobilizing Activity and Adverse Events Associated with Escalating Doses of AMD3100 in Healthy Volunteers.

Steven J. Lemery, MD, Matthew M. Hsieh, MD, Aleah Smith, Sheila Rao, Hanh M. Khuu, Donohue Theresa, PA, Jennifer M. Karpovich, NP, Lisa Cook, RN, Rose Goodwin, RN, Carol Boss, MPH, Gary Calandra, Nancy Geller, PhD, John Tisdale, MD, Richard Childs, MD

Blood (2007) 110 (11): 3278.

https://doi.org/10.1182/blood.V110.11.3278.3278

Published: 2007

Journal Articles

Impact of KIR and HLA Genotypes on Outcome in Nonmyeloablative Hematopoietic Cell Transplantation (HCT) Using HLA Matched Related Donors.

Ramaprasad Srinivasan, MD, PhD, Mary Carrington, Ph.D., Dante Suffredini, M.S., Aleah Smith, Maureen Martin, Ph.D, Maria Berg, M.S., A. John Barrett, M.D., Shivani Srivastava, M.D, Andreas Lundqvist, Ph.D., Hisayuki Yokoyoma, M.D., Bipin N. Savani, M.D., Richard W. Childs, M.D.

Blood (2006) 108 (11): 323.

https://doi.org/10.1182/blood.V108.11.323.323

Published: 2006

Journal Articles

Adoptive Infusion of Alloreactive Donor NK Cells Reduces GVHD, Mediates Anti-Tumor Effects and Prolongs Survival in Recipients of MHC-Matched Hematopoietic Cell Transplantation.

Andreas Lundqvist, PhD, Philip McCoy, PhD, Leigh Samsel, MS, Aleah Smith, MS, Shivani Srivastava, MD, Nanae Harashima, PhD, Hisayuki Yokoyama, PhD, Maria Berg, MS, Richard Childs, MD

Blood (2006) 108 (11): 3233.

https://doi.org/10.1182/blood.V108.11.3233.3233

Published: 2006

Journal Articles

In Vitro and In Vivo Sensitization of Malignant Cells to Autologous Natural Killer Cell Cytotoxicity Following Exposure to Bortezomib.

Andreas Lundqvist, PhD, Kristy Greeneltch, PhD, Maria Berg, MS, Shivani Srivastava, MD, Nanae Harashima, PhD, Hisayuki Yokoyama, PhD, Aleah Smith, MS, Scott Abrams, PhD, Richard Childs, MD

Blood (2006) 108 (11): 925.

https://doi.org/10.1182/blood.V108.11.925.925

Published: 2006

NARROW

High Dose Plerixafor Is Safe and Mobilizes Higher Numbers of CD34+ Cells Compared with Standard Dose Plerixafor

Optimizing Lentiviral Transduction of Human Natural Killer Cells

HLA Alloantibody Persistence and De Novo Production of HLA Alloantibodies of Donor Origin Following Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation.

Adoptive Transfer of Escalating Doses of Ex Vivo Expanded Autologous Natural Killer (NK) Cells In Patients with Advanced Malignancies Following Bortezomib Treatment to Sensitize to NK-TRAIL Cytotoxicity

siRNA Inactivation of the Inhibitory Receptor NKG2A Augments the Anti-Tumor Effects of Adoptively Transferred NK Cells In Tumor-Bearing Hosts

In Vitro Assessment of Tolerance and Rejection Occurring After Co-Transplantation of Allogeneic Umbilical Cord Blood and Haploidentical CD34+ Cells as Treatment for Severe Aplastic Anemia

Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells

Lentiviral Transduction of Ex Vivo Expanded Natural Killer Cells with a CD19 Chimeric Antigen Receptor Induces Cytotoxicity against Resistant B Cell Malignancies

A Rhesus Macaque Model to Optimize Adoptive NK Cell Therapy

Adoptively-Infused NK Cells Maintain Their Antitumor Effects in Vivo in the Presence of CyclosporineA (CSA)

Bortezomib Enhances the Antitumor Activity of Adoptively Infused Natural Killer Cells In Vivo: A Novel Approach To Override KIR-Mediated Inhibition of NK Cell Cytotoxicity.

The Proteasome Inhibitor Bortezomib Simultaneously Enhances NK Cell Tumor Cytotoxicity While Paradoxically Reducing Antigen Specific T-Cell Tumor Cytotoxicity.

Cyclosporine A (CSA) Significantly Reduces the Cytotoxic Effects of In Vitro Expanded NK Cells: Implications for Adoptive NK Cell Therapy in the Setting of Allogeneic Hematopoietic Stem Cell Transplantation (HCT).

Reduced Incidence of Acute Graft Versus Host Disease (GVHD) and Transplant-Related Mortality (TRM) with the Addition of Short-Course Mini-Dose Methotrexate (MTX) to Cyclosporine (CSA) as GVHD Prophylaxis Following Nonmyeloablative Hematopoietic Stem Cell Transplantation (NST).

A Pilot Study Evaluating the CD34+ Cell Mobilizing Activity and Adverse Events Associated with Escalating Doses of AMD3100 in Healthy Volunteers.

Impact of KIR and HLA Genotypes on Outcome in Nonmyeloablative Hematopoietic Cell Transplantation (HCT) Using HLA Matched Related Donors.

Adoptive Infusion of Alloreactive Donor NK Cells Reduces GVHD, Mediates Anti-Tumor Effects and Prolongs Survival in Recipients of MHC-Matched Hematopoietic Cell Transplantation.

In Vitro and In Vivo Sensitization of Malignant Cells to Autologous Natural Killer Cell Cytotoxicity Following Exposure to Bortezomib.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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