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Journal Articles

Adenine Base Editing Improves Erythropoiesis in Diamond-Blackfan Anemia Syndrome Patient-Derived Induced Pluripotent Stem Cells

Shruthi Suryaprakash, Lei Han, Garret Manquen, Varun Katta, Damian Krzyzanowski, Jayaram Prasad, Nikitha Nimmagada, Kalin Mayberry, Nana Liu, Yan Ju, Yu Yao, Kelsey Ray, Marcin Wlodarski, Shengdar Q Tsai, Jonathan S Yen, Mitchell J Weiss, Senthil Velan Bhoopalan

Blood (2024) 144 (Supplement 1): 4088.

https://doi.org/10.1182/blood-2024-209312

Published: 2024

Journal Articles

Hematopoietic Stem Cells Supporting Fetal Erythropoiesis Are Differentially Regulated By Small and Large Ribosomal Subunits

Yuefeng Tang, Te Ling, Rashid Mehmood, Mushran Khan, Julien Papoin, James Palis, Laurie A. Steiner, Sébastien Durand, Leonard I. Zon, Senthil Velan Bhoopalan, Mitchell J Weiss, Jeffrey Michael Lipton, Naomi Taylor, Patrick G. Gallagher, Mohandas Narla, John D. Crispino, Lionel Blanc

Blood (2024) 144 (Supplement 1): 195.

https://doi.org/10.1182/blood-2024-210699

Published: 2024

Journal Articles

miRNA-144/451 Regulates Cell Surface TfR1 Expression in Normal and β-Thalassemic Erythroblasts

Georgios E. Christakopoulos, Alfonso G. Fernandez, Yu Yao, Rahul Telange, Dudley W. Michael, Tomas Ganz, Elizabeta Nemeth, Mitchell J Weiss

Blood (2024) 144 (Supplement 1): 2478.

https://doi.org/10.1182/blood-2024-210302

Published: 2024

Journal Articles

Identification of Breakpoints of RHD Hybrid Alleles By Long-Read Sequencing

Ti-Cheng Chang, Jing Yu, Bensheng Ju, Melanie Loyd, Granger Ridout, Geoffrey A.M. Neale, Jane S Hankins, Mitchell J Weiss, Gorka Ochoa, Sunitha Vege, Stella T. Chou, John Easton, Yan Zheng

Blood (2024) 144 (Supplement 1): 4031.

https://doi.org/10.1182/blood-2024-198223

Published: 2024

Journal Articles

SAGES1: Clinical Translation of CRISPR Genome Editing Strategy to Induce Fetal Hemoglobin to Treat Sickle Cell Disease

Blood (2024) 144 (Supplement 1): 146.

https://doi.org/10.1182/blood-2024-211182

Published: 2024

Journal Articles

Testing Rapamycin As an Anti-Adhesion Therapy for Sickle Cell Disease

Danitza Nebor, Mitchell J Weiss, Jonathan M. Flanagan

Blood (2024) 144 (Supplement 1): 5296.

https://doi.org/10.1182/blood-2024-212384

Published: 2024

Journal Articles

Motixafortide for Hematopoietic Stem and Progenitor Cell Mobilization and Collection in Sickle Cell Disease

Alexis Kristine Leonard, Akshay Sharma, Yogindra Persaud, Parul Rai, Darla Pickett, Renee Massey, Neha Das Gupta, Subodh Selukar, Salem M. Akel, Leigh Poston, Yan Zheng, Ella Sorani, Irit Gliko Kabir, Mitchell J Weiss, Stephen Gottschalk, Julie Kanter, Matthew Hsieh, John Tisdale

Blood (2024) 144 (Supplement 1): 2100.1.

https://doi.org/10.1182/blood-2024-200330

Published: 2024

Journal Articles

A moonlighting job for α-globin in blood vessels

Prabhodh S. Abbineni, Srishti Baid, Mitchell J. Weiss

Blood (2024) 144 (8): 834–844.

https://doi.org/10.1182/blood.2023022192

Published: 2024

Journal Articles

Reduced Polycomb Repressor Complex 2 (PRC2) Activity and Increased TP53 Activity Mediate Hematopoietic Stem Cell Dysfunction in RPS19-Mutated Diamond-Blackfan Anemia

Senthil V Bhoopalan, Ruopeng Feng, Thiyagaraj Mayuranathan, Kalin Mayberry, Yoonjeong Jang, Jonathan S Yen, Yu Yao, Lance Palmer, Yong Cheng, Marcin W Wlodarski, Mitchell J. Weiss

Blood (2023) 142 (Supplement 1): 2732.

https://doi.org/10.1182/blood-2023-190069

Published: 2023

Journal Articles

A Genotype Validated Bimodal Method for the Large-Scale Identification and Phenotyping of Persons with Sickle Cell Disease Using Electronic Health Record Data

Kristin Wuichet, Clifford M Takemoto, Robert Cronin, Martha Barton, Pei-Lin Chen, Santosh L. Saraf, Mitchell J. Weiss, Michael R. DeBaun

Blood (2023) 142 (Supplement 1): 7164.

https://doi.org/10.1182/blood-2023-190521

Published: 2023

Journal Articles

Iron Restriction Alleviates β-Thalassemia By Stimulating ULK1-Mediated Autophagy of Free α-Globin

Alfonso G. Fernandez, Georgios E. Christakopoulos, Dudley E. Michael, Razan B. A. Sweileh, Rahul Telange, Heather Sheppard, Yu Yao, Jingjing Zhang, Vania Manolova, Elizabeta Nemeth, Tomas Ganz, Mitchell J. Weiss

Blood (2023) 142 (Supplement 1): 558.

https://doi.org/10.1182/blood-2023-185008

Published: 2023

Journal Articles

Loss of miR-144/451 alleviates β-thalassemia by stimulating ULK1-mediated autophagy of free α-globin

Julia Keith, Georgios E. Christakopoulos, Alfonso G. Fernandez, Yu Yao, Jingjing Zhang, Kalin Mayberry, Rahul Telange, Razan B. A. Sweileh, Michael Dudley, Camilla Westbrook, Heather Sheppard, Mitchell J. Weiss, Christophe Lechauve

Blood (2023) 142 (10): 918–932.

https://doi.org/10.1182/blood.2022017265

Published: 2023

Includes: Supplemental data

Journal Articles

ETV6 Represses TNF during Stress Hematopoiesis and Regulates HSC Self Renewal

Mackenzie Bloom, Rebekah Baskin-Doerfler, Ninad Oak, Ruopeng Feng, Xujie Zhao, Chunliang Li, Patrick Ozark, Katherine Verbist, Alexa Stroh, Sabrin Albeituni, JaQuel Maise, Mitchell J. Weiss, Shannon McKinney-Freeman, Jun J.J. Yang, Kim E. Nichols

Blood (2022) 140 (Supplement 1): 2849–2850.

https://doi.org/10.1182/blood-2022-168076

Published: 2022

Journal Articles

Base Editing for Therapeutic Induction of Fetal Hemoglobin in β-Thalassemia

Georgios E. Christakopoulos, Thiyagaraj Mayuranathan, Alfonso G. Fernandez, Kalin Mayberry, Yu Yao, Rahul Telange, Michael Dudley, Rachel Levine, Erin Dempsey, David R. Liu, Jonathan S Yen, Mitchell J. Weiss

Blood (2022) 140 (Supplement 1): 10660–10661.

https://doi.org/10.1182/blood-2022-169391

Published: 2022

Journal Articles

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Blood (2022) 140 (Supplement 1): 7784–7785.

https://doi.org/10.1182/blood-2022-162639

Published: 2022

Journal Articles

Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression

Sarah K. Topfer, Ruopeng Feng, Peng Huang, Lana C. Ly, Gabriella E. Martyn, Gerd A. Blobel, Mitchell J. Weiss, Kate G. R. Quinlan, Merlin Crossley

Blood (2022) 139 (14): 2107–2118.

https://doi.org/10.1182/blood.2021014205

Published: 2022

Includes: Supplemental data

Journal Articles

Optimization of Autologous Hematopoietic Progenitor Stem Cell Apheresis Collection from Plerixafor-Mobilized Patients with Sickle Cell Disease

Blood (2021) 138 (Supplement 1): 1770.

https://doi.org/10.1182/blood-2021-146669

Published: 2021

Journal Articles

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

Ruopeng Feng, Thiyagaraj Mayuranathan, Peng Huang, Phillip A Doerfler, Yichao Li, Yu Yao, Jingjing Zhang, Lance E. Palmer, Peng Xu, Kalin Mayberry, Shaela Wright, Chunliang Li, Yong Cheng, Gerd A. Blobel, M. Celeste Simon, Mitchell J. Weiss

Blood (2021) 138 (Supplement 1): 574.

https://doi.org/10.1182/blood-2021-149901

Published: 2021

Journal Articles

A Novel RPS19 -Edited Hematopoietic Stem Cell Model of Diamond-Blackfan Anemia for Development of Lentiviral Vector Gene Therapy

Senthil Velan Bhoopalan, Jonathan Yen, Thiyagaraj Mayuranathan, Yu Yao, Kalin Mayberry, Sheng Zhou, Robert Throm, Marcin W. Wlodarski, Mitchell J. Weiss

Blood (2021) 138 (Supplement 1): 859.

https://doi.org/10.1182/blood-2021-147557

Published: 2021

Journal Articles

Dynamic CTCF binding directly mediates interactions among cis -regulatory elements essential for hematopoiesis

Qian Qi, Li Cheng, Xing Tang, Yanghua He, Yichao Li, Tiffany Yee, Dewan Shrestha, Ruopeng Feng, Peng Xu, Xin Zhou, Shondra Pruett-Miller, Ross C. Hardison, Mitchell J. Weiss, Yong Cheng

Blood (2021) 137 (10): 1327–1339.

https://doi.org/10.1182/blood.2020005780

Published: 2021

Includes: Supplemental data

NARROW

Adenine Base Editing Improves Erythropoiesis in Diamond-Blackfan Anemia Syndrome Patient-Derived Induced Pluripotent Stem Cells

Hematopoietic Stem Cells Supporting Fetal Erythropoiesis Are Differentially Regulated By Small and Large Ribosomal Subunits

miRNA-144/451 Regulates Cell Surface TfR1 Expression in Normal and β-Thalassemic Erythroblasts

Identification of Breakpoints of RHD Hybrid Alleles By Long-Read Sequencing

SAGES1: Clinical Translation of CRISPR Genome Editing Strategy to Induce Fetal Hemoglobin to Treat Sickle Cell Disease

Testing Rapamycin As an Anti-Adhesion Therapy for Sickle Cell Disease

Motixafortide for Hematopoietic Stem and Progenitor Cell Mobilization and Collection in Sickle Cell Disease

A moonlighting job for α-globin in blood vessels

Reduced Polycomb Repressor Complex 2 (PRC2) Activity and Increased TP53 Activity Mediate Hematopoietic Stem Cell Dysfunction in RPS19-Mutated Diamond-Blackfan Anemia

A Genotype Validated Bimodal Method for the Large-Scale Identification and Phenotyping of Persons with Sickle Cell Disease Using Electronic Health Record Data

Iron Restriction Alleviates β-Thalassemia By Stimulating ULK1-Mediated Autophagy of Free α-Globin

Loss of miR-144/451 alleviates β-thalassemia by stimulating ULK1-mediated autophagy of free α-globin

ETV6 Represses TNF during Stress Hematopoiesis and Regulates HSC Self Renewal

Base Editing for Therapeutic Induction of Fetal Hemoglobin in β-Thalassemia

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression

Optimization of Autologous Hematopoietic Progenitor Stem Cell Apheresis Collection from Plerixafor-Mobilized Patients with Sickle Cell Disease

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

A Novel RPS19 -Edited Hematopoietic Stem Cell Model of Diamond-Blackfan Anemia for Development of Lentiviral Vector Gene Therapy

Dynamic CTCF binding directly mediates interactions among cis -regulatory elements essential for hematopoiesis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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