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Journal Articles

Adenine Base Editing Improves Erythropoiesis in Diamond-Blackfan Anemia Syndrome Patient-Derived Induced Pluripotent Stem Cells

Shruthi Suryaprakash, Lei Han, Garret Manquen, Varun Katta, Damian Krzyzanowski, Jayaram Prasad, Nikitha Nimmagada, Kalin Mayberry, Nana Liu, Yan Ju, Yu Yao, Kelsey Ray, Marcin Wlodarski, Shengdar Q Tsai, Jonathan S Yen, Mitchell J Weiss, Senthil Velan Bhoopalan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4088.
https://doi.org/10.1182/blood-2024-209312
Published: 2024
Journal Articles

Mutational Permutations of a Single Amino Acid Exert Divergent Phenotypic Effects in Human, Mice, and Cellular Models of SAMD9L Bone Marrow Failure Disorder

Sushree S Sahoo, Charnise Goodings-Harris, Shondra Miller, Maria Angeles Lillo Osuna, Baranda S Hansen, Lei Han, Ti-Cheng Chang, Tim Lammens, Mattias Hofmans, Marta Derecka, Barbara De Moerloose, Marcin W Wlodarski
Journal: Blood
Blood (2022) 140 (Supplement 1): 2216–2217.
https://doi.org/10.1182/blood-2022-169400
Published: 2022
Journal Articles

Germline Loss-of-Function Mutations in MDM4 Cause p53-Dependent Hematopoietic Cell Death in Patients with Variable Bone Marrow Failure Phenotypes

Richa Sharma, Senthil Bhoopalan, Lei Han, Yu Yao, Kalin Mayberry, Baranda S Hansen, Shondra Miller, Claudia Khurana, Miriam Erlacher, Marcin W Wlodarski
Journal: Blood
Blood (2022) 140 (Supplement 1): 2955–2956.
https://doi.org/10.1182/blood-2022-162614
Published: 2022