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Journal Articles

Nidogen-1, a Novel Player in KMT2A-Rearranged Pediatric Acute Myeloid Leukemia Patients, Expressed in the Leukemic Stem Cell

Jolien Vanhooren, Larissa Deneweth, Luca Pagliaro, Zhiyao Ren, Barbara Depreter, Mattias Hofmans, Barbara De Moerloose, Tim Lammens

Blood (2024) 144 (Supplement 1): 6134.

https://doi.org/10.1182/blood-2024-200598

Published: 2024

Journal Articles

Ultra-Deep Sequencing and Single Cell Multi-Omics Characterize Measurable Residual Disease and Identify Therapy-Survived Clone in Pediatric Acute Myeloid Leukemia

Borhan R. R Saeed, Anastasia Saboli, Anna Rehammar, Adam Molnar, Erik Delsing Malmberg, Barbara Depreter, Giti Shah Barkhordar, Barbara De Moerloose, Tim Lammens, Lars Palmqvist, Jonas Abrahamsson, Linda Fogelstrand

Blood (2024) 144 (Supplement 1): 4994.

https://doi.org/10.1182/blood-2024-210493

Published: 2024

Journal Articles

Deciphering the Role and Therapeutic Potential of Macrophage Marker CD68 in Pediatric Acute Myeloid Leukemia

Laurens Van Camp, Jolien Vanhooren, Barbara Depreter, Mattias Hofmans, Inge D'Hont, Christophe Chantrain, Laurence Dedeken, An Van Damme, Anne Uyttebroeck, Tim Lammens, Barbara De Moerloose

Blood (2024) 144 (Supplement 1): 6093.

https://doi.org/10.1182/blood-2024-201130

Published: 2024

Journal Articles

A 46 Long Non-Coding RNAs Expression Signature Accurately Predicts Relapse and Acts As an Independent Prognostic Factor in Pediatric Acute Myeloid Leukemia

Zhiyao Ren, Jolien Vanhooren, Charlotte Derpoorter, Barbara De Moerloose, Tim Lammens

Blood (2023) 142 (Supplement 1): 1569.

https://doi.org/10.1182/blood-2023-173154

Published: 2023

Journal Articles

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Blood (2023) 142 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2023-179306

Published: 2023

Journal Articles

Mutational Permutations of a Single Amino Acid Exert Divergent Phenotypic Effects in Human, Mice, and Cellular Models of SAMD9L Bone Marrow Failure Disorder

Sushree S Sahoo, Charnise Goodings-Harris, Shondra Miller, Maria Angeles Lillo Osuna, Baranda S Hansen, Lei Han, Ti-Cheng Chang, Tim Lammens, Mattias Hofmans, Marta Derecka, Barbara De Moerloose, Marcin W Wlodarski

Blood (2022) 140 (Supplement 1): 2216–2217.

https://doi.org/10.1182/blood-2022-169400

Published: 2022

Journal Articles

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-138501

Published: 2020

Journal Articles

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-139376

Published: 2020

Journal Articles

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Blood (2020) 136 (8): 957–973.

https://doi.org/10.1182/blood.2019002548

Published: 2020

Includes: Supplemental data

Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Blood (2020) 135 (19): 1685–1695.

https://doi.org/10.1182/blood.2019003880

Published: 2020

Includes: Supplemental data

Journal Articles

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Mattias Hofmans, MD, Barbara Depreter, PhD PharmD, Tim Lammens, PhD, Helene Cave, PharmD, PhD, Christian Flotho, MD PhD, Henrik Hasle, Valerie de Haas, MD PhD, Charlotte M. Niemeyer, MD, Jan Stary, Prof., MD PhD, Pieter Van Vlierberghe, PhD, Jan Philippé, MD PhD, Barbara De Moerloose, MD PhD

Blood (2019) 134 (Supplement_1): 1701.

https://doi.org/10.1182/blood-2019-123715

Published: 2019

Journal Articles

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Barbara Depreter, PhD PharmD, Mattias Hofmans, MD, Eva Terras, Anne Uyttebroeck, MD, An Van Damme, MD, Alina Ferster, MD, Jutte Van der Werff Ten Bosch, MD, Marie-Françoise Dresse, MD PhD, Karl Vandepoele, PhD, Barbara De Moerloose, MD PhD, Jan Philippé, MD PhD, Tim Lammens, PhD

Blood (2019) 134 (Supplement_1): 1457.

https://doi.org/10.1182/blood-2019-125538

Published: 2019

Journal Articles

Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Renate De Smedt, MSc, Sofie Peirs, PhD, Julie Morscio, PhD, Juliette Roels, MSc, Steven Goossens, PhD, Aurore Touzart, MD, Anne Uyttebroeck, Nadine Van Roy, PhD, Tim Lammens, PhD, Lara Mussolin, PhD, Elizabeth Macyntire, MD PhD, Peter Vandenberghe, MD PhD, Pieter Van Vlierberghe, PhD

Blood (2017) 130 (Supplement 1): 1445.

https://doi.org/10.1182/blood.V130.Suppl_1.1445.1445

Published: 2017

Journal Articles

A Novel Multiplex NGS-Based Digital MLPA Assay for Copy Number Detection of 700 Target Sequences in Childhood Acute Lymphoblastic Leukemia

Anne Benard, Ilse Zondervan, Jan Schouten, Karel de Groot, Farzaneh Ghazavi, Virinder Sarhadi, Pieter Van Vlierberghe, PhD, Barbara De Moerloose, MD, Christine Harrison, Claire Schwab, Sakari Knuutila, Tim Lammens, Suvi Savola

Blood (2016) 128 (22): 4071.

https://doi.org/10.1182/blood.V128.22.4071.4071

Published: 2016

Journal Articles

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Thomas B. Alexander, MD MPH, Zhaohui Gu, PhD, John K Choi, MD, Mignon L. Loh, MD, John Horan, MD MPH, Barbara Buldini, MD, Giuseppe Basso, Sarah Elitzur, MD, C. Michel Zwaan, MD PhD, Valerie de Haas, MD PhD, Allen Eng Juh Yeoh, MD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD, PhD, Tim Lammens, Barbara De Moerloose, MD, Li Zhou, PhD, Hiroki Hori, MD PhD, Anthony V. Moorman, PhD, Andrew S. Moore, MBBS FRACP PhD, Ondrej Hrusak, MD PhD, Soheil Meshinchi, MD PhD, Etan Orgel, MD MS, Meenakshi Devidas, PhD, Stephen P. Hunger, MD, Jamie M Guidry Auvil, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Leandro C. Hermida, Patee Gesuwan, Marco A. Marra, PhD, Yussanne Ma, PhD, Andrew J. Mungall, Richard Moore, PhD, Daniela S. Gerhard, PhD, Xueyuan Cao, Lei Shi, PhD, Stanley Pounds, PhD, Hiroto Inaba, MD PhD, Charles Mullighan, MBBS, MSc, MD

Blood (2016) 128 (22): 454.

https://doi.org/10.1182/blood.V128.22.454.454

Published: 2016

Journal Articles

Unique Long Non-Coding RNA Expression Signature in ETV6/RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia

Farzaneh Ghazavi, Barbara De Moerloose, MD, Wouter Van Loocke, Annelynn Wallaert, Alina Ferster, Marleen Bakkus, PhD, Genevieve Plat, MD, Eric Delabesse, PharmD, PhD, Anne Uyttebroeck, Filip Van Nieuwerburgh, PharmD, Prof, Dieter Deforce, PharmD, Prof, Nadine van Roy, MD Prof, Frank Speleman, Prof, Yves Benoit, Tim Lammens, Pieter van Vlierberghe, Prof

Blood (2016) 128 (22): 3920.

https://doi.org/10.1182/blood.V128.22.3920.3920

Published: 2016

Journal Articles

RPPA-Based Protein Profiling Reveals Enhanced PI3K/AKT/mTOR Signaling in ETV6/RUNX1-Positive Acute Lymphoblastic Leukemia Patients with Low CD200 Expression

Farzaneh Ghazavi, Valentina Serafin, PhD, Pieter Rondou, PhD, Tim Lammens, Frank Speleman, Prof, Benedetta Accordi, PhD, Barbara De Moerloose, MD, Pieter Van Vlierberghe, Prof

Blood (2016) 128 (22): 890.

https://doi.org/10.1182/blood.V128.22.890.890

Published: 2016

Journal Articles

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Blood (2016) 127 (9): 1163–1172.

https://doi.org/10.1182/blood-2015-09-667808

Published: 2016

Includes: Supplemental data

Journal Articles

Excellent Outcome in Pediatric AML with Response Guided Chemotherapy without Allogeneic HSCT in First Complete Remission: Results from Protocol DB-AML01

Eveline de Bont, MD PhD, Ardine Reedijk, MSc, Tim Lammens, PhD, Valerie de Haas, MD PhD, Barbara Denys, PhD, Laurence Dedeken, MD, Marry van den Heuvel, MD PhD, Maroeska Loo, MD PhD, Anne Uyttebroeck, An Vandamme, MD PhD, Jutte VanderWerff-ten Bosch, MD PhD, Jozsef Zsiros, Gertjan J.L. Kaspers, MD PhD, Barbara Moerloose, MD PhD

Blood (2015) 126 (23): 2506.

https://doi.org/10.1182/blood.V126.23.2506.2506

Published: 2015

Journal Articles

Identification of Candidate Oncogenes and Chromosomal Breakpoint Sequencing By Targeted Locus Amplification in T-Cell Acute Lymphoblastic Leukemia

Eric M Vroegindeweij, PhD, Tim Lammens, PhD, Erik Splinter, PhD, Anne Uyttebroeck, Kirsten Canté-Barrett, PhD, Jessica GCAM Buijs-Gladdines, Wilco K Smits, Peter Vandenberghe, MD PhD, Max J van Min, PhD, Rob Pieters, MD PhD, Pieter Van Vlierberghe, PhD, Jules PP Meijerink, PhD

Blood (2015) 126 (23): 1409.

https://doi.org/10.1182/blood.V126.23.1409.1409

Published: 2015

NARROW

Nidogen-1, a Novel Player in KMT2A-Rearranged Pediatric Acute Myeloid Leukemia Patients, Expressed in the Leukemic Stem Cell

Ultra-Deep Sequencing and Single Cell Multi-Omics Characterize Measurable Residual Disease and Identify Therapy-Survived Clone in Pediatric Acute Myeloid Leukemia

Deciphering the Role and Therapeutic Potential of Macrophage Marker CD68 in Pediatric Acute Myeloid Leukemia

A 46 Long Non-Coding RNAs Expression Signature Accurately Predicts Relapse and Acts As an Independent Prognostic Factor in Pediatric Acute Myeloid Leukemia

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Mutational Permutations of a Single Amino Acid Exert Divergent Phenotypic Effects in Human, Mice, and Cellular Models of SAMD9L Bone Marrow Failure Disorder

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

A Novel Multiplex NGS-Based Digital MLPA Assay for Copy Number Detection of 700 Target Sequences in Childhood Acute Lymphoblastic Leukemia

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Unique Long Non-Coding RNA Expression Signature in ETV6/RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia

RPPA-Based Protein Profiling Reveals Enhanced PI3K/AKT/mTOR Signaling in ETV6/RUNX1-Positive Acute Lymphoblastic Leukemia Patients with Low CD200 Expression

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Excellent Outcome in Pediatric AML with Response Guided Chemotherapy without Allogeneic HSCT in First Complete Remission: Results from Protocol DB-AML01

Identification of Candidate Oncogenes and Chromosomal Breakpoint Sequencing By Targeted Locus Amplification in T-Cell Acute Lymphoblastic Leukemia

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American Society of Hematology

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American Society of Hematology

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