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Journal Articles

Deciphering the Role and Therapeutic Potential of Macrophage Marker CD68 in Pediatric Acute Myeloid Leukemia

Laurens Van Camp, Jolien Vanhooren, Barbara Depreter, Mattias Hofmans, Inge D'Hont, Christophe Chantrain, Laurence Dedeken, An Van Damme, Anne Uyttebroeck, Tim Lammens, Barbara De Moerloose

Blood (2024) 144 (Supplement 1): 6093.

https://doi.org/10.1182/blood-2024-201130

Published: 2024

Journal Articles

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Blood (2023) 141 (7): 743–755.

https://doi.org/10.1182/blood.2022016975

Published: 2023

Includes: Supplemental data

Journal Articles

Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia

Llucia Albertí-Servera, Sofie Demeyer, Inge Govaerts, Toon Swings, Jolien De Bie, Olga Gielen, Marco Brociner, Lucienne Michaux, Johan Maertens, Anne Uyttebroeck, Kim De Keersmaecker, Nancy Boeckx, Heidi Segers, Jan Cools

Blood (2021) 137 (6): 801–811.

https://doi.org/10.1182/blood.2020006996

Published: 2021

Includes: Supplemental data

Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Blood (2020) 135 (19): 1685–1695.

https://doi.org/10.1182/blood.2019003880

Published: 2020

Includes: Supplemental data

Journal Articles

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Barbara Depreter, PhD PharmD, Mattias Hofmans, MD, Eva Terras, Anne Uyttebroeck, MD, An Van Damme, MD, Alina Ferster, MD, Jutte Van der Werff Ten Bosch, MD, Marie-Françoise Dresse, MD PhD, Karl Vandepoele, PhD, Barbara De Moerloose, MD PhD, Jan Philippé, MD PhD, Tim Lammens, PhD

Blood (2019) 134 (Supplement_1): 1457.

https://doi.org/10.1182/blood-2019-125538

Published: 2019

Journal Articles

Evolution of Clinically Relevant Subclones during Chemotherapy Treatment of ALL As Determined By Single-Cell DNA and RNA Sequencing

Llucia Albertí Servera, PhD, Sofie Demeyer, PhD, Inge Govaerts, MD PhD, Olga Gielen, Heidi Segers, MD PhD, Anne Uyttebroeck, MD, Nancy Boeckx, Johan A. Maertens, MD PhD, Kim De Keersmaecker, PhD, Jan Cools, PhD

Blood (2019) 134 (Supplement_1): 2749.

https://doi.org/10.1182/blood-2019-123046

Published: 2019

Journal Articles

Results of Inter-B-NHL Ritux 2010 - Phase II Study of DA-EPOCH-R for Children and Adolescents with Primary Mediastinal Large B-Cell Lymphoma (PMLBL) on Behalf of European Intergroup for Childhood Non Hodgkin's Lymphoma (EICNHL) and Children's Oncology Group (COG)

G A Amos Burke, Thomas G. Gross, MD PhD, Marta Pillon, Veronique Minard-colin, Raphael F Delgado, József Zsíros, Anne Uyttebroeck, Jean Michon, Catherine M. Bollard, MD FRACP, FRCPA, Monika Csoka, Donald A Barkauskas, Keith Wheatley, DPhil, Anne Aupérin, Catherine Patte

Blood (2017) 130 (Supplement 1): 4124.

https://doi.org/10.1182/blood.V130.Suppl_1.4124.4124

Published: 2017

Journal Articles

Fertility Status Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Blood (2017) 130 (Supplement 1): 2563.

https://doi.org/10.1182/blood.V130.Suppl_1.2563.2563

Published: 2017

Journal Articles

Socioeconomic Outcomes Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Blood (2017) 130 (Supplement 1): 2191.

https://doi.org/10.1182/blood.V130.Suppl_1.2191.2191

Published: 2017

Journal Articles

Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Renate De Smedt, MSc, Sofie Peirs, PhD, Julie Morscio, PhD, Juliette Roels, MSc, Steven Goossens, PhD, Aurore Touzart, MD, Anne Uyttebroeck, Nadine Van Roy, PhD, Tim Lammens, PhD, Lara Mussolin, PhD, Elizabeth Macyntire, MD PhD, Peter Vandenberghe, MD PhD, Pieter Van Vlierberghe, PhD

Blood (2017) 130 (Supplement 1): 1445.

https://doi.org/10.1182/blood.V130.Suppl_1.1445.1445

Published: 2017

Journal Articles

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors

Antonis Dagklis, Sofie Demeyer, Jolien De Bie, Enrico Radaelli, Daphnie Pauwels, Sandrine Degryse, Olga Gielen, Carmen Vicente, Roel Vandepoel, Ellen Geerdens, Anne Uyttebroeck, Nancy Boeckx, Charles E. de Bock, Jan Cools

Blood (2016) 128 (23): 2642–2654.

https://doi.org/10.1182/blood-2016-03-703454

Published: 2016

Includes: Supplemental data

Journal Articles

Unique Long Non-Coding RNA Expression Signature in ETV6/RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia

Farzaneh Ghazavi, Barbara De Moerloose, MD, Wouter Van Loocke, Annelynn Wallaert, Alina Ferster, Marleen Bakkus, PhD, Genevieve Plat, MD, Eric Delabesse, PharmD, PhD, Anne Uyttebroeck, Filip Van Nieuwerburgh, PharmD, Prof, Dieter Deforce, PharmD, Prof, Nadine van Roy, MD Prof, Frank Speleman, Prof, Yves Benoit, Tim Lammens, Pieter van Vlierberghe, Prof

Blood (2016) 128 (22): 3920.

https://doi.org/10.1182/blood.V128.22.3920.3920

Published: 2016

Journal Articles

Prophylactic CNS Therapy (with or without Radiation Therapy) in Medium-High Risk Acute Lymphoblastic Leukemia (ALL) Children: Long-Term Outcome Evaluation of the Randomized BFM-Oriented Trial 58832 (period 1983-1989) of the EORTC Children Leukemia Group

Blood (2016) 128 (22): 2775.

https://doi.org/10.1182/blood.V128.22.2775.2775

Published: 2016

Journal Articles

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Blood (2015) 126 (23): 793.

https://doi.org/10.1182/blood.V126.23.793.793

Published: 2015

Journal Articles

Identification of Candidate Oncogenes and Chromosomal Breakpoint Sequencing By Targeted Locus Amplification in T-Cell Acute Lymphoblastic Leukemia

Eric M Vroegindeweij, PhD, Tim Lammens, PhD, Erik Splinter, PhD, Anne Uyttebroeck, Kirsten Canté-Barrett, PhD, Jessica GCAM Buijs-Gladdines, Wilco K Smits, Peter Vandenberghe, MD PhD, Max J van Min, PhD, Rob Pieters, MD PhD, Pieter Van Vlierberghe, PhD, Jules PP Meijerink, PhD

Blood (2015) 126 (23): 1409.

https://doi.org/10.1182/blood.V126.23.1409.1409

Published: 2015

Journal Articles

Excellent Outcome in Pediatric AML with Response Guided Chemotherapy without Allogeneic HSCT in First Complete Remission: Results from Protocol DB-AML01

Eveline de Bont, MD PhD, Ardine Reedijk, MSc, Tim Lammens, PhD, Valerie de Haas, MD PhD, Barbara Denys, PhD, Laurence Dedeken, MD, Marry van den Heuvel, MD PhD, Maroeska Loo, MD PhD, Anne Uyttebroeck, An Vandamme, MD PhD, Jutte VanderWerff-ten Bosch, MD PhD, Jozsef Zsiros, Gertjan J.L. Kaspers, MD PhD, Barbara Moerloose, MD PhD

Blood (2015) 126 (23): 2506.

https://doi.org/10.1182/blood.V126.23.2506.2506

Published: 2015

Journal Articles

ALK-Positive Anaplastic Large Cell Lymphoma with the Variant EEF1G-, RNF213- and Atic-ALK Fusions Is Featured By Copy Number Gain of the Rearranged ALK Gene

Iwona Wlodarska, Jo-Anne van der Krogt, Julio Finalet Ferreiro, Jacobs Kris, Geerdens Ellen, Anne Uyttebroeck, Peter Vandenberghe, MDPhD, Thomas Tousseyn, MDPhD, Jan Cools, PhD

Blood (2015) 126 (23): 3654.

https://doi.org/10.1182/blood.V126.23.3654.3654

Published: 2015

Journal Articles

Prognostic Relevance of CD200 /Btla Deletions in Pediatric Precursor-B Cell Acute Lymphoblastic Leukemia Treated According to the EORTC-CLG 58951 Protocol

Blood (2014) 124 (21): 2394.

https://doi.org/10.1182/blood.V124.21.2394.2394

Published: 2014

Journal Articles

Non-Invasive Detection of Genomic Imbalances in Hodgkin/Reed-Sternberg Cells in Early and Advanced Stage Hodgkin Lymphoma By Sequencing of Circulating Cell-Free DNA

Peter Vandenberghe, MDPhD, Iwona Wlodarska, PhD, Thomas Tousseyn, MDPhD, Luc Dehaspe, PhD, Daan Dierickx, MDPhD, Magali Verheecke, MD, Anne Uyttebroeck, MDPhD, Oliver Bechter, MDPhD, Michel Delforge, MDPhD, Vincent Vandecaveye, MDPhD, Nathalie Brison, PhD, Gregor EG Verhoef, MDPhD, Eric Legius, MDPhD, Frederic Amant, MDPhD, Joris R Vermeesch, PhD

Blood (2014) 124 (21): LBA-4.

https://doi.org/10.1182/blood.V124.21.LBA-4.LBA-4

Published: 2014

Journal Articles

Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing

Kiran Tawana, MD, Aline Renneville, Jun Wang, PhD, Panayiotis Georgiades, Xavier Thomas, MD, Valerie Mialou, MD, Aleksander Savic, MD, Frederik W Van Delft, MD PhD, Jennifer G. Treleaven, MD, Sameena Iqbal, Norio Asou, MD, PhD, Naokuni Uike, MD, Konstanze Döhner, MD, Lars Bullinger, MD, PhD, Matthias Stelljes, MD, Csaba Bödör, PhD, James D. Cavenagh, MD, Doris Steinemann, PhD, Tim Ripperger, MD, Brigitte Schlegelberger, MD, PhD, Peter Vandenberghe, MD, PhD, Anne Uyttebroeck, MD, Josep F. Nomdedeu, MD, Henrik Hjorth-Hansen, MD, PhD, Rosemary E Gale, PhD, Cynthia L. Toze, MD, FRCP(C), Michael J. Barnett, BMBS, FRCPC, FRCP, FRCPath, Marianna Zombori, MD, Krisztian Kallay, MD, Jiri Pavlu, MD, Pim Mutsaers, MD, Fred H Menko, MD, Angela Thomas, PhD, FRCPath, FRCP, MB, BS, Christine Wright, MD, Jessica Okosun, MD, Chey Loveday, PhD, Pierre Fenaux, MD, PhD, Hamish Scott, PhD, Claude Preudhomme, Claude Chelala, PhD, Alison Male, MD, Carolyn J. Owen, MD, FRCPC, Matthew Smith, MD, PhD, Jude Fitzgibbon, PhD

Blood (2013) 122 (21): 740.

https://doi.org/10.1182/blood.V122.21.740.740

Published: 2013

NARROW

Deciphering the Role and Therapeutic Potential of Macrophage Marker CD68 in Pediatric Acute Myeloid Leukemia

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Deciphering Molecular Heterogeneity in Pediatric AML Using a Cancer Vs Normal Transcriptomic Approach

Evolution of Clinically Relevant Subclones during Chemotherapy Treatment of ALL As Determined By Single-Cell DNA and RNA Sequencing

Results of Inter-B-NHL Ritux 2010 - Phase II Study of DA-EPOCH-R for Children and Adolescents with Primary Mediastinal Large B-Cell Lymphoma (PMLBL) on Behalf of European Intergroup for Childhood Non Hodgkin's Lymphoma (EICNHL) and Children's Oncology Group (COG)

Fertility Status Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Socioeconomic Outcomes Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors

Unique Long Non-Coding RNA Expression Signature in ETV6/RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia

Prophylactic CNS Therapy (with or without Radiation Therapy) in Medium-High Risk Acute Lymphoblastic Leukemia (ALL) Children: Long-Term Outcome Evaluation of the Randomized BFM-Oriented Trial 58832 (period 1983-1989) of the EORTC Children Leukemia Group

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Identification of Candidate Oncogenes and Chromosomal Breakpoint Sequencing By Targeted Locus Amplification in T-Cell Acute Lymphoblastic Leukemia

Excellent Outcome in Pediatric AML with Response Guided Chemotherapy without Allogeneic HSCT in First Complete Remission: Results from Protocol DB-AML01

ALK-Positive Anaplastic Large Cell Lymphoma with the Variant EEF1G-, RNF213- and Atic-ALK Fusions Is Featured By Copy Number Gain of the Rearranged ALK Gene

Prognostic Relevance of CD200 /Btla Deletions in Pediatric Precursor-B Cell Acute Lymphoblastic Leukemia Treated According to the EORTC-CLG 58951 Protocol

Non-Invasive Detection of Genomic Imbalances in Hodgkin/Reed-Sternberg Cells in Early and Advanced Stage Hodgkin Lymphoma By Sequencing of Circulating Cell-Free DNA

Familial AML With Germline CEBPA Mutations: Extended Clinical Outcomes and Analysis Of Secondary Mutations Using Whole Exome Sequencing

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American Society of Hematology

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