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Journal Articles

Sox11-induced reprogramming of B2 cells to a B1a-like phenotype promotes Mantle Cell Lymphoma in mice

Tim Pieters, Luca Pagliaro, André De Almeida, Fritz Offner, Tom Taghon, Pieter Van Vlierberghe, Steven Goossens

Blood (2025) 146 (Supplement 1): 143.

https://doi.org/10.1182/blood-2025-143

Published: 2025

Journal Articles

SOX11 skews T-cell development and synergizes with LMO2 and MYCN to form T-cell acute lymphoblastic leukemia in mouse models

André De Almeida, Kasper Thorhauge Christensen, Igor Fijalkowski, Marlies Vanden Bempt, Jan Cools, Tom Taghon, Panagiotis Ntziachristos, Pieter Van Vlierberghe, Steven Goossens, Tim Pieters

Blood (2025) 146 (Supplement 1): 335.

https://doi.org/10.1182/blood-2025-335

Published: 2025

Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Blood (2024) 144 (22): 2319–2326.

https://doi.org/10.1182/blood.2024024300

Published: 2024

Includes: Supplemental data

Journal Articles

Jmjd3 Drives Immature T-Cell Lymphoblastic Leukemia

Cristina Borin, Tim Pieters, Pieter Van Vlierberghe, Panagiotis Ntziachristos

Blood (2023) 142 (Supplement 1): 4341.

https://doi.org/10.1182/blood-2023-190510

Published: 2023

Journal Articles

A Dual Role of SOX11 Expression in the Formation of T-Cell Acute Lymphoblastic Leukemia in Mouse Models

André De Almeida, Sara T'Sas, Els Van Ammel, Pieter Van Vlierberghe, Tim Pieters, Steven Goossens

Blood (2023) 142 (Supplement 1): 1406.

https://doi.org/10.1182/blood-2023-179584

Published: 2023

Journal Articles

PDGFR-β As a New Therapeutic Target in T-Cell Acute Lymphoblastic Leukemia

Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Steven Goossens, Pieter Van Vlierberghe

Blood (2022) 140 (Supplement 1): 11513–11514.

https://doi.org/10.1182/blood-2022-168556

Published: 2022

Journal Articles

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Blood (2022) 140 (Supplement 1): 1009–1010.

https://doi.org/10.1182/blood-2022-162930

Published: 2022

Journal Articles

Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL

Feng Yan, Cedric Tremblay, Francine Garret-Bakelman, Jesslyn Saw, Matthew P. McCormack, Shokoufeh Abdollahi, Pieter Van Vlierberghe, David Powell, Nicholas C. Wong, David J. Curtis

Blood (2022) 140 (Supplement 1): 5898–5899.

https://doi.org/10.1182/blood-2022-169201

Published: 2022

Journal Articles

Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair

Silvia Alvarez, Ana C. da Silva Almeida, Robert Albero, Mayukh Biswas, Angelica Barreto-Galvez, Thomas S. Gunning, Anam Shaikh, Tomas Aparicio, Agnieszka Wendorff, Erich Piovan, Pieter Van Vlierberghe, Steven Gygi, Jean Gautier, Advaitha Madireddy, Adolfo A. Ferrando

Blood (2022) 139 (23): 3418–3429.

https://doi.org/10.1182/blood.2021014103

Published: 2022

Includes: Supplemental data

Journal Articles

ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

Blood (2022) 139 (3): 399–412.

https://doi.org/10.1182/blood.2020010405

Published: 2022

Includes: Supplemental data

Journal Articles

Metabolic Changes in Venetoclax Resistance Are Determined By Differentiation State in T-Cell Acute Lymphoblastic Leukemia

Alessandra Di Grande, Andrew Roe, Thomas Lefeivre, Theresa E. Leon, Marc R. Mansour, Jonathan Bond, Pieter Van Vlierberghe, Triona Ni Chonghaile

Blood (2021) 138 (Supplement 1): 3401.

https://doi.org/10.1182/blood-2021-152489

Published: 2021

Journal Articles

SOX11 Functions As an Oncogene in Lmo2-Driven T-Cell Lymphoblastic Leukemia (T-ALL)

André De Almeida, Tim Pieters, Sara T'Sas, Steven Goossens, Pieter Van Vlierberghe

Blood (2021) 138 (Supplement 1): 1136.

https://doi.org/10.1182/blood-2021-149471

Published: 2021

Journal Articles

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-138501

Published: 2020

Journal Articles

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Blood (2020) 136 (8): 957–973.

https://doi.org/10.1182/blood.2019002548

Published: 2020

Includes: Supplemental data

Journal Articles

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie Taveirne, Sigrid Wahlen, Wouter Van Loocke, Laura Kiekens, Eva Persyn, Els Van Ammel, Katrien De Mulder, Juliette Roels, Laurentijn Tilleman, Marc Aumercier, Patrick Matthys, Filip Van Nieuwerburgh, Tessa C. C. Kerre, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq

Blood (2020) 136 (3): 288–298.

https://doi.org/10.1182/blood.2020005204

Published: 2020

Includes: Supplemental data

Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Blood (2020) 135 (19): 1685–1695.

https://doi.org/10.1182/blood.2019003880

Published: 2020

Includes: Supplemental data

Journal Articles

Chemotherapy at the wheel of ALL relapse

Julie Morscio, Pieter Van Vlierberghe

Blood (2020) 135 (1): 4–5.

https://doi.org/10.1182/blood.2019003870

Published: 2020

Journal Articles

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Alessandra Di Grande, BSc, Sofie Piers, Pieter Van Vlierberghe, PhD, Triona Ni Chonghaile, PhD BSc

Blood (2019) 134 (Supplement_1): 3800.

https://doi.org/10.1182/blood-2019-127970

Published: 2019

Journal Articles

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

Mattias Hofmans, MD, Barbara Depreter, PhD PharmD, Tim Lammens, PhD, Helene Cave, PharmD, PhD, Christian Flotho, MD PhD, Henrik Hasle, Valerie de Haas, MD PhD, Charlotte M. Niemeyer, MD, Jan Stary, Prof., MD PhD, Pieter Van Vlierberghe, PhD, Jan Philippé, MD PhD, Barbara De Moerloose, MD PhD

Blood (2019) 134 (Supplement_1): 1701.

https://doi.org/10.1182/blood-2019-123715

Published: 2019

Journal Articles

ZEB2 and LMO2 Drive Immature T-Cell Lymphoblastic Leukemia Via Distinct Oncogenic Mechanisms

Steven Goossens, PhD, Jueqiong Wang, PhD, Cedric Tremblay, PhD, Pieter Van Vlierberghe, PhD, Geert Berx, PhD, Tom Taghon, PhD, Jody J Haigh, PhD

Blood (2018) 132 (Supplement 1): 3916.

https://doi.org/10.1182/blood-2018-99-111104

Published: 2018

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Sox11-induced reprogramming of B2 cells to a B1a-like phenotype promotes Mantle Cell Lymphoma in mice

SOX11 skews T-cell development and synergizes with LMO2 and MYCN to form T-cell acute lymphoblastic leukemia in mouse models

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Jmjd3 Drives Immature T-Cell Lymphoblastic Leukemia

A Dual Role of SOX11 Expression in the Formation of T-Cell Acute Lymphoblastic Leukemia in Mouse Models

PDGFR-β As a New Therapeutic Target in T-Cell Acute Lymphoblastic Leukemia

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL

Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair

ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

Metabolic Changes in Venetoclax Resistance Are Determined By Differentiation State in T-Cell Acute Lymphoblastic Leukemia

SOX11 Functions As an Oncogene in Lmo2-Driven T-Cell Lymphoblastic Leukemia (T-ALL)

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Chemotherapy at the wheel of ALL relapse

The Splenic Microenvironment Is a Novel Site of Relapse Following ABT-199 Treatment

Long Non-Coding RNAs As Novel Therapeutic Targets in Juvenile Myelomonocytic Leukemia: Proof of Concept Study

ZEB2 and LMO2 Drive Immature T-Cell Lymphoblastic Leukemia Via Distinct Oncogenic Mechanisms

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