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Journal Articles

Impact of Fludarabine Dosage on Outcomes in Large B-Cell Lymphoma Patients Treated with CAR T-Cell Therapy: A Retrospective Study on Behalf of the Ctiwp of the EBMT

Guillaume Dachy, Jarl E Mooyaart, Ibrahim Yakoub-Agha, Michael Daskalakis, Ludovic Gabellier, Victoria Potter, Christof Scheid, Peter Dreger, Didier Blaise, Anne Huynh, Caroline Besley, Matthew Collin, Peter Vandenberghe, Lucia Lopez Corral, Gerald Wulf, Francis A. Ayuk, Carlos Solano, Edouard Forcade, Jorinde D. Hoogenboom, Jurgen Kuball, Annalisa Ruggeri, Florent Malard
Journal: Blood
Blood (2024) 144 (Supplement 1): 3456.
https://doi.org/10.1182/blood-2024-211010
Published: 2024
Journal Articles

Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of BMS-986353 (CC-97540), a CD19-Directed Chimeric Antigen Receptor (CAR) T Cell Therapy Manufactured Using a Next-Generation Process, for Severe, Refractory Autoimmune Diseases: Updated Data from Ongoing Phase 1, Multicenter, Open-Label Studies

Fabian Mueller, Krish Patel, Ran Reshef, Mohamad Cherry, Richard Nash, Ernesto Ayala, Jingmei Hsu, Jacques Azzi, Peter Vandenberghe, Roch Houot, Bastian von Tresckow, Giuseppina Stifano, Ashley Koegel, Susana Falcon, Burhan Chaudhry, Lisa Kelly, Jerill Thorpe, Alyse Frisbee, Sam Charab, Sharmila Das, Thomas Ly, Ken Ogasawara, Paolo Caimi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2088.
https://doi.org/10.1182/blood-2024-194525
Published: 2024
Journal Articles

Remote Patient Monitoring for Early Detection of Cytokine Release Syndrome in Myeloma Patients: A Comparative Study between Standard Care and Remote Monitoring

Anneleen Vanhellemont, Annemarie Coolbrandt, Evi Vandeneede, Gwen Aerts, Lise Lynen, Yoline Soeffers, Annouschka Laenen, Peter Vandenberghe, Michel Delforge
Journal: Blood
Blood (2024) 144 (Supplement 1): 3664.
https://doi.org/10.1182/blood-2024-203013
Published: 2024
Journal Articles

High Body Mass Index Is Associated with Favorable Outcome in Younger Patients Receiving CD19 CAR T-Cell Therapy for B-Cell Lymphoma: A Retrospective Study from the EBMT Transplant Complications Working Party

Christian R. Schultze-Florey, Christophe Peczynski, William Boreland, Michael Daskalakis, Anne Sirvent, Ibrahim Yakoub-Agha, Maria-Luisa Schubert, Christof Scheid, Anne Huynh, Victoria Potter, Didier Blaise, Matthew P. Collin, Sr., Rafael Hernani, Gerald G. Wulf, Francis A. Ayuk, Caroline Besley, Lucia Lopez Corral, Edouard Forcade, Peter Vandenberghe, Dominik Schneidawind, Matthias Stelljes, Friedrich Stölzel, Bertram Glass, Ivan Sergeevich Moiseev, Helene Schoemans, Olaf Penack, Christian Koenecke, Zinaida Peric
Journal: Blood
Blood (2023) 142 (Supplement 1): 4867.
https://doi.org/10.1182/blood-2023-187393
Published: 2023
Journal Articles

Genomic, Transcriptional, and Immunological Validation of Distinct Molecular Subtypes of Classic Hodgkin Lymphoma through Tissue-Based and Noninvasive Methods

Stefan K. Alig, Mohammad Shahrokh Esfahani, Andrea Garofalo, Michael Yu Li, Cédric Rossi, Timothy Flerlage, Jamie E. Flerlage, Ragini Adams, Michael S. Binkley, Navika Shukla, Michael Jin, Mari Olsen, Adele Telenius, Jurik A Mutter, Joseph Schroers-Martin, Brian J. Sworder, Shinya Rai, Daniel King, Andre Schultz, Jan Lukas Bögeholz, Shengqin Su, Karan R Kathuria, Chih Long Liu, Xiaoman Kang, Deanna M. Langfitt, Kristine Faye Pobre-Piza, Feng Tian, Maya J. Strohband, Valeria Spina, Thomas Tousseyn, Lieselot Buedts, Luc-Matthieu Fornecker, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C Lynch, Herve Ghesquieres, Olivier Casasnovas, David M. Kurtz, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 177.
https://doi.org/10.1182/blood-2023-186810
Published: 2023
Journal Articles

Improved Overall Survival with Axicabtagene Ciloleucel Vs Standard of Care in Second-Line Large B-Cell Lymphoma Among the Elderly: A Subgroup Analysis of ZUMA-7

Marie José Kersten, Umar Farooq, Aaron P. Rapoport, Frederick L. Locke, Lori A. Leslie, Armin Ghobadi, David B. Miklos, Caron A. Jacobson, Javier L. Munoz, Patrick B Johnston, Samantha M. Jaglowski, Ian W. Flinn, Tom van Meerten, Miguel-Angel Perales, Peter Vandenberghe, Peter A. Riedell, Kathleen Dorritie, David Szwajcer, Dimitrios Tzachanis, Saran Vardhanabhuti, Linqiu Du, Simone Filosto, Shilpa A. Shahani, Christina To, Jason Westin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1761.
https://doi.org/10.1182/blood-2023-173873
Published: 2023
Journal Articles

Efficacy of CD19-Directed CAR T Cell Therapy in Patients with Primary or Secondary CNS Lymphoma - an Analysis of the EBMT Lymphoma WP and the Gocart Coalition

Anna Ossami Saidy, Stephan Fuhrmann, Christophe Peczynski, Ariane Boumendil, Eva Michel, Jacques-Emmanuel Galimard, Hervé Finel, Michael Daskalakis, Urban Novak, David Beauvais, Peter Vandenberghe, Nicolaus Kröger, Ron Ram, Jürgen Finke, Matthias Stelljes, Gerald G. Wulf, Wolfgang Andreas Bethge, Malte von Bonin, Gesine Bug, Andrea Kuhnl, Jakob Passweg, Sr., Friedrich Stoelzel, Bastian von Tresckow, Anna Maria Sureda Balari, Peter Dreger, Norbert Schmitz, Bertram Glass
Journal: Blood
Blood (2023) 142 (Supplement 1): 1031.
https://doi.org/10.1182/blood-2023-174883
Published: 2023
Journal Articles

Efficacy and Safety of Vodobatinib in Patients (pts) with Chronic Phase Philadelphia Positive Chronic Myeloid Leukemia (Ph+ CML): A Sub Group Analysis By Lines of Tyrosine Kinase Inhibitor (TKI) Therapy

Jorge E. Cortes, Tapan Saikia, Dong-Wook Kim, Yesid Alvarado, Franck E. Nicolini, Krishnakumar Rathnam, Navin Khattry, Sachin Punatar, Jane F. Apperley, Aude Charbonnier, Michael Deininger, Hugues de Lavallade, Nikki Granacher, Carlo Gambacorti-Passerini, Alessandro Lucchesi, Michael Mauro, Peter Vandenberghe, Gregor Verhoef, Andrew R. Whiteley, Arijit Nag, Shashikant Apte, Siu-Long Yao, Sandeep Inamdar, Ruchika Irene Dillu, Jayasree Sreenivasan, Geetanjali Chimote
Journal: Blood
Blood (2022) 140 (Supplement 1): 205–207.
https://doi.org/10.1182/blood-2022-166452
Published: 2022
Journal Articles

Viral cfDNA Profiling Reveals Distinct EBV Subtypes and Stratifies Risk in Hodgkin Lymphomas

Andrea Garofalo, Stefan K. Alig, Joseph Schroers-Martin, Ragini Malika Shyam, Mari Olsen, David M. Kurtz, Cédric Rossi, Andre Schultz, Karan R. Kathuria, Chih Long Liu, Valeria Spina, Jamie E. Flerlage, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C. Lynch, Olivier Casasnovas, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1318–1319.
https://doi.org/10.1182/blood-2022-159230
Published: 2022
Journal Articles

Trial in Progress: A Randomized Phase II Study of MB-CART2019.1 Compared to Standard of Care Therapy in Patients with Relapsed/Refractory DLBCL Ineligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation - DALY 2-EU Trial

Peter Borchmann, Peter Vandenberghe, Alvaro Urbano-Ispizua, Corinne Haioun, Francois Lemonnier, Laimonas Griskevicius, Sébastien Maury, Silke Holtkamp, Birte Friedrichs, Gregor Zadoyan, Linda Hanssens, Toon Overstijns, Mario Assenmacher, Ulf Bethke, Iris Bürger, Olaf Reer, Ulrich Jaeger, Marie José Kersten
Journal: Blood
Blood (2022) 140 (Supplement 1): 12784–12785.
https://doi.org/10.1182/blood-2022-164650
Published: 2022
Journal Articles

Distinct Molecular Subtypes of Classic Hodgkin Lymphoma Identified By Comprehensive Noninvasive Profiling

Stefan K. Alig, Mohammad Shahrokh Esfahani, Michael Y. Li, Ragini Malika Adams, Andrea Garofalo, Michael C. Jin, Mari Olsen, Adèle Telenius, Brian Sworder, Joseph Schroers-Martin, Daniel A. King, Cédric Rossi, Andre Schultz, Karan R. Kathuria, Chih Long Liu, Valeria Spina, Lieselot Buedts, Jamie E. Flerlage, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C. Lynch, Olivier Casasnovas, David M. Kurtz, Lianna J. Marks, Michael P. Link, Marc André, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1295–1296.
https://doi.org/10.1182/blood-2022-164744
Published: 2022
Journal Articles

An Update of Safety and Efficacy Results from Phase 1 Dose-Escalation and Expansion Study of Vodobatinib, a Novel Oral BCR-ABL1 Tyrosine Kinase Inhibitor (TKI), in Patients with Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Failing Prior TKI Therapies

Jorge E. Cortes, Tapan Saikia, Dong-Wook Kim, Yesid Alvarado, Franck E. Nicolini, Krishnakumar Rathnam, Navin Khattry, Jane F Apperley, Michael W. Deininger, Hugues de Lavallade, Aude Charbonnier, Nikki Granacher, Carlo Gambacorti-Passerini, Alessandro Lucchesi, Michael J. Mauro, Peter Vandenberghe, Gregor Verhoef, Andrew R. Whiteley, Arijit Nag, Vivek S Radhakrishnan, Shashikant Apte, Siu-Long Yao, Sandeep Inamdar, Jayasree Sreenivasan, Ruchika Irene Dillu, Geetanjali Chimote
Journal: Blood
Blood (2021) 138 (Supplement 1): 309.
https://doi.org/10.1182/blood-2021-152548
Published: 2021
Journal Articles

Primary Analysis of ZUMA-7: A Phase 3 Randomized Trial of Axicabtagene Ciloleucel (Axi-Cel) Versus Standard-of-Care Therapy in Patients with Relapsed/Refractory Large B-Cell Lymphoma

Frederick L. Locke, David B. Miklos, Caron Jacobson, Miguel-Angel Perales, Marie José Kersten, Olalekan O. Oluwole, Armin Ghobadi, Aaron P. Rapoport, Joseph P. McGuirk, John M. Pagel, Javier Muñoz, Umar Farooq, Tom Van Meerten, Patrick M. Reagan, Anna Sureda, Ian W. Flinn, Peter Vandenberghe, Kevin Song, Michael Dickinson, Monique C. Minnema, Peter A. Riedell, Lori A. Leslie, Sridhar Chaganti, Yin Yang, Simone Filosto, Marco Schupp, Christina To, Paul Cheng, Leo I. Gordon, Jason R. Westin
Journal: Blood
Blood (2021) 138 (Supplement 1): 2.
https://doi.org/10.1182/blood-2021-148039
Published: 2021
Journal Articles

14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia

Danika Di Giacomo, Roberta La Starza, Paolo Gorello, Fabrizia Pellanera, Zeynep Kalender Atak, Kim De Keersmaecker, Valentina Pierini, Christine J. Harrison, Silvia Arniani, Martina Moretti, Nicoletta Testoni, Giovanna De Santis, Giovanni Roti, Caterina Matteucci, Renato Bassan, Peter Vandenberghe, Stein Aerts, Jan Cools, Beat Bornhauser, Jean-Pierre Bourquin, Rocco Piazza, Cristina Mecucci
Journal: Blood
Blood (2021) 138 (9): 773–784.
https://doi.org/10.1182/blood.2020010510
Published: 2021
Includes: Supplemental data
Journal Articles

Phase 1 Trial of Vodobatinib, a Novel Oral BCR-ABL1 Tyrosine Kinase Inhibitor (TKI): Activity in CML Chronic Phase Patients Failing TKI Therapies Including Ponatinib

Jorge E. Cortes, MD, Tapan Saikia, MD, Dong-Wook Kim, MD, Yesid Alvarado, MD, Franck E Nicolini, MDPhD, Navin Khattry, MD DM, Krishnakumar Rathnam, MD DM, Jane Apperley, FRCP, FRCPath, MB, Michael W. Deininger, MD PhD, Hugues de Lavallade, MD PhD, Aude Charbonnier, MD PhD, Nikki Granacher, MD, Carlo Gambacorti-Passerini, MD, Alessandro Lucchesi, MD, Michael J. Mauro, MD, Gregor Verhoef, MD PhD, Peter Vandenberghe, MD, Andrew R. Whiteley, MD, Shashikant Apte, MD FRCPA, Siu-Long Yao, MD, Mudgal Kothekar, MD, Jayasree Sreenivasan, MSc, Bimba HV, MD, Geetanjali Chimote, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 51–52.
https://doi.org/10.1182/blood-2020-139847
Published: 2020
Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De Smedt, Julie Morscio, Lindy Reunes, Juliette Roels, Valentina Bardelli, Beatrice Lintermans, Wouter Van Loocke, Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, Marc R. Mansour, Anne Uyttebroeck, Peter Vandenberghe, Roberta La Starza, Cristina Mecucci, Tim Lammens, Nadine Van Roy, Barbara De Moerloose, João T. Barata, Tom Taghon, Steven Goossens, Pieter Van Vlierberghe
Journal: Blood
Blood (2020) 135 (19): 1685–1695.
https://doi.org/10.1182/blood.2019003880
Published: 2020
Includes: Supplemental data
Journal Articles

FER and FES tyrosine kinase fusions in follicular T-cell lymphoma

Koen Debackere, Jo-Anne van der Krogt, Thomas Tousseyn, Julio Antonio Finalet Ferreiro, Katrien Van Roosbroeck, Lukas Marcelis, Carlos Graux, Daan Dierickx, Geneviève Ameye, Peter Vandenberghe, Lucienne Michaux, Jan Cools, Iwona Wlodarska
Journal: Blood
Blood (2020) 135 (8): 584–588.
https://doi.org/10.1182/blood.2019002401
Published: 2020
Includes: Supplemental data
Journal Articles

Unraveling the Landscape of Copy Number Aberrations in Hodgkin Lymphoma: A Joint KU Leuven and Lysa Study on Circulating Cell Free DNA

Lieselot Buedts, Luc Mathieu Fornecker, Julio Finalet-Ferreiro, PhD, Luc Dehaspe, PhD, Thomas Tousseyn, MD PhD, Olivier Gheysens, MD PhD, Julien Lazarovici, MD, Rene-Olivier Casasnovas, MD, Christiane Copie, MD PhD, Gregor Verhoef, MD PhD, Sanne Smits, Joris Vermeesch, PhD, Marc Andre, MD PhD, Peter Vandenberghe, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2836.
https://doi.org/10.1182/blood-2018-99-113402
Published: 2018
Journal Articles

Noninvasive Genotyping and Monitoring of Classical Hodgkin Lymphoma

Michael C. Jin, Joseph G Schroers-Martin, MD, David M. Kurtz, MD PhD, Lieselot Buedts, Mohammad S Esfahani, PhD, Charles Macaulay, BS, Brian Sworder, MD PhD, Joanne Soo, BS, Cynthia Glover, Mark Roschewski, MD, Wyndham H. Wilson, MD PhD, Ulrich Dührsen, Prof, MD PhD, Andreas Hüttmann, MD, Davide Rossi, MD PhD, Gianluca Gaidano, MD PhD, Jason R. Westin, MD, Lauren S. Maeda, MD, Ranjana H Advani, MD, Peter Vandenberghe, MD, Maximilian Diehn, MD PhD, Arash A. Alizadeh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2838.
https://doi.org/10.1182/blood-2018-99-119140
Published: 2018
Journal Articles

Lymphoma Virome Dynamics Revealed By Cell-Free DNA Sequencing

Joseph G Schroers-Martin, MD, Andrea Garofalo, Joanne Soo, BS, Michael C. Jin, David M. Kurtz, MDPhD, Lieselot Buedts, Ulrich Dührsen, Prof, MD PhD, Andreas Hüttmann, MD, Anne Ségolène Cottereau, Michel Meignan, Olivier Casasnovas, MD, Jason R. Westin, MD, Gianluca Gaidano, MD PhD, Davide Rossi, MD PhD, Mark Roschewski, MD, Wyndham H. Wilson, MD PhD, Ranjana H Advani, MD, Peter Vandenberghe, MD, Maximilian Diehn, MD PhD, Kiran Khush, MD, Ash A. Alizadeh, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2861.
https://doi.org/10.1182/blood-2018-99-119905
Published: 2018