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Tom Van Meerten
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Journal Articles

Zamtocabtagene autoleucel, a tandem CD20-CD19 directed CAR-T cell therapy as second-line treatment for Relapsed/Refractory large B-cell lymphoma: primary analysis of the randomized, pivotal DALY 2-EU study.

Free
Peter Borchmann, Tom Van Meerten, Pierre Bories, Peter Dreger, Laszlo Gopsca, Pim Mutsaers, Matthias Edinger, Arpad Illes, Bastian von Tresckow, Peter Neumeister, Normann Steiner, Ulrich Jaeger, Ana Triguero Moreno, Laimonas Griškevičius, Gloria Iacoboni, François Lemonnier, Jaap Van Doesum, Nirav Shah, Rimas Orentas, Stefan Miltenyi, Toon Overstijns, Iris Bürger, Gregor Zadoyan, Corinne Brillant, Pearl van Heteren, Silke Holtkamp, Peter Vandenberghe
Journal: Blood
Blood (2025) 146 (Supplement 1): 669.
https://doi.org/10.1182/blood-2025-669
Published: 2025
Journal Articles

Transformed FL shows improved survival after CAR T-cell therapy compared to de novo LBCL, but early transformation (<12 months) defines a poor-risk subgroup: Results from a nationwide cohort

Free
Hilde Van Der Galien, Pim Mutsaers, Margot Jak, Marjolein Van Der Poel, Marije Nijk, Kees Meijer, Marieke Tienstra, Kylie Keijzer, Janneke De Boer, Astrid Demandt, Amaria Vledder, Anne Spanjaart, Elise Pennings, Maria Kuipers, Marie José Kersten, Jaap Van Doesum, Anne Niezink, Joost Vermaat, Suzanne Van Dorp, Tom Van Meerten
Journal: Blood
Blood (2025) 146 (Supplement 1): 959.
https://doi.org/10.1182/blood-2025-959
Published: 2025
Journal Articles

Higher helios⁺ treg levels pre- and post-CAR T infusion are associated with inferior outcomes in patients with LBCL

Free
Hilde Van Der Galien, Nienke Smit, Marije Nijk, Marieke Tienstra, Thies Moolenaar, Janneke De Boer, Kylie Keijzer, Jaap Van Doesum, Anne Niezink, Gerwin A. Huls, Kees Meijer, Tom Van Meerten
Journal: Blood
Blood (2025) 146 (Supplement 1): 1779.
https://doi.org/10.1182/blood-2025-1779
Published: 2025
Journal Articles

High risk of bleeding following CAR T-cell therapy: Insights from the dutch “Follow that CAR!” registry

Free
Amica Ko, Pim Mutsaers, Lukas Van Kleij, Frank Leebeek, Amaria Vledder, Elise Pennings, Anne Spanjaart, Janneke De Boer, Astrid Demandt, Jaap Van Doesum, Suzanne Van Dorp, Margot Jak, Maria Kuipers, Tom Van Meerten, Marjolein Van Der Poel, Joost Vermaat, Marie José Kersten, Mandy Lauw
Journal: Blood
Blood (2025) 146 (Supplement 1): 315.
https://doi.org/10.1182/blood-2025-315
Published: 2025
Journal Articles

Two-year update of ZUMA-2 Cohort 3: Brexucabtagene autoleucel (Brexu-cel) in patients (pts) with relapsed/refractory mantle cell lymphoma (R/R MCL) who had not received prior Bruton tyrosine kinase inhibitor (BTKi) therapy

Free
Tom Van Meerten, Marie José Kersten, Gloria Iacoboni, Georg Hess, Pim Mutsaers, Alejandro Martin Garcia-Sancho, Andre Goy, Eva Gine, Brian Hill, Wen-Kai Weng, Martin Dreyling, Patrick Reagan, Krish Patel, Ahmed Galal, Charles Herbaux, Robin Sanderson, Dan Zheng, Sabina Adhikary, Wangshu Zhang, Rita Damico Khalid, Ioana Kloos, Michael Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 1799.
https://doi.org/10.1182/blood-2025-1799
Published: 2025
Journal Articles

Early intervention for cytokine release syndrome after chimeric antigen receptor T-cell therapy is associated with an increased risk of cytopenias and infections in patients with large B-cell lymphoma

Free
Gloria Iacoboni, Victor Navarro, Ana Africa Martin Lopez, Kai Rejeski, Imran Malik, Paula Fernández-Caldas, Hilde Van Der Galien, Ana Benzaquen, Javier Delgado Serrano, Sergi Camarillas, Mariana Bastos-Oreiro, Tobias Tix, Cecilia Carpio, Mario Sánchez-Salinas, Fátima de la Cruz, Pablo Silva, Maeve O'Reilly, Carolyn Maharaj, Marieke Tienstra, Alejandro Martin Garcia-Sancho, Juan Luis Reguera, Rafael Hernani, Mi Kwon, Lucia Lopez Corral, Claire Roddie, Marion Subklewe, Tom Van Meerten, Pere Barba
Journal: Blood
Blood (2025) 146 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2025-1944
Published: 2025
Journal Articles

Central nervous system relapse is uncommon after chimeric antigen receptor T-cell therapy for relapsed/refractory large B-cell lymphoma

Free
Gloria Iacoboni, Emmanuel Bachy, Victor Navarro, Tom Van Meerten, Paula Fernández-Caldas, Carolyn Maharaj, Ana Africa Martin Lopez, Tobias Tix, Ana Benzaquen, Sandra Perez, Javier Delgado Serrano, Sergi Camarillas, Cristina García Herce, Mariana Bastos-Oreiro, Pierre Sesques, Imran Malik, Maria Teresa Villalobos, Ana Jiménez Ubieto, Lucia Medina, Sonia González De Villambrosia, Claire Roddie, Hilde Van Der Galien, Marieke Tienstra, Maryam Idlhaj, Pablo Silva, Lucia Lopez Corral, Paola Villafuerte Gutiérrez, Ana Saus Carreres, Santiago Browne, Blanca Sanchez, Daniel García Belmonte, Fátima de la Cruz, Marion Subklewe, Rafael Hernani, Mi Kwon, Maeve O'Reilly, Kai Rejeski, Alejandro Martin Garcia-Sancho, Leyre Bento De Miguel, Pere Barba, Pau Abrisqueta
Journal: Blood
Blood (2025) 146 (Supplement 1): 5497.
https://doi.org/10.1182/blood-2025-5497
Published: 2025
Journal Articles

Brexucabtagene autoleucel for BTKi-naive relapsed/refractory mantle cell lymphoma: primary analysis of ZUMA-2 Cohort 3

Open Access
Clinical Trials & Observations
Tom van Meerten, Marie José Kersten, Gloria Iacoboni, Georg R. Hess, Pim G.N.J. Mutsaers, Alejandro Martin Martin Garcia-Sancho, Andre Goy, Eva Gine, Brian T. Hill, Wen-Kai Weng, Patrick M. Reagan, Krish Patel, Ahmed Galal, Charles Herbaux, Robin Sanderson, Edouard Forcade, Max S. Topp, Roch Houot, Dan Zheng, Wangshu Zhang, Justyna Kanska, Rhine R Shen, Rita Damico Khalid, Ioana Kloos, Martin Dreyling, Michael L Wang
Journal: Blood
Blood blood.2025029734.
https://doi.org/10.1182/blood.2025029734
Published: 2025
Includes: Supplemental data
Journal Articles

Primary Analysis of ZUMA-2 Cohort 3: Brexucabtagene Autoleucel (Brexu-Cel) in Patients (Pts) with Relapsed/Refractory Mantle Cell Lymphoma (R/R MCL) Who Were Naive to Bruton Tyrosine Kinase Inhibitors (BTKi)

Free
Tom van Meerten, M.J. Kersten, Gloria Iacoboni, Georg Hess, Pim Mutsaers, Alejandro Martín García-Sancho, Andre Goy, Eva Gine, Brian T. Hill, Wen-Kai Weng, Martin Dreyling, Patrick M. Reagan, Krish Patel, Ahmed Galal, Charles Herbaux, Robin Sanderson, Dan Zheng, Justyna Kanska, Wangshu Zhang, Rita Damico Khalid, Ioana Kloos, Michael Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 748.
https://doi.org/10.1182/blood-2024-198021
Published: 2024
Journal Articles

Population-Based External Validation of the CAR-Hematotox Score to Predict CAR T Cell Related Toxicity and Outcome in R/R LBCL Patients

Free
Janneke W. de Boer, Kylie Keijzer, Suzanne van Dorp, Pim G.N.J. Mutsaers, Anne G.H. Niezink, Jaap A. van Doesum, Yasmina I.M. Serroukh, Louise W. Muntendam, Astrid E. Pulles, Esther J. Kret, Aniko Sijs-Szabo, Jesse Oomen, Astrid M.P. Demandt, Wendy B.C. Stevens, Maria T. Kuipers, Elise R.A. Pennings, Anne M. Spanjaart, Marie José Kersten, Margot Jak, Lisanne V. van Dijk, Marjolein W.M. van der Poel, Joost S.P. Vermaat, Tom van Meerten
Journal: Blood
Blood (2024) 144 (Supplement 1): 1747.
https://doi.org/10.1182/blood-2024-209879
Published: 2024
Journal Articles

Site-Specific Analysis of Extranodal Involvement Reveals Distinct Efficacy Outcomes with CAR T-Cell Therapy in Large B-Cell Lymphoma Patients

Free
Gloria Iacoboni, Kai Rejeski, Victor Navarro Garces, Tom van Meerten, Alex Rampotas, Ana Africa Martin Lopez, Juan Luis Reguera, Mariana Bastos-Oreiro, Claire Roddie, Ana Benzaquen, Cecilia Carpio, Javier Delgado Serrano, Maria Landwehr, Sophia Stock, Pablo Silva De Tena, Pau Abrisqueta Costa, Janneke W. De Boer, Lucia Lopez Corral, Rafael Hernani, Marion Subklewe, Mi Kwon, Maeve O'Reilly, Pere Barba
Journal: Blood
Blood (2024) 144 (Supplement 1): 471.
https://doi.org/10.1182/blood-2024-205809
Published: 2024
Journal Articles

Whole Body CD8 + T Cell PET Imaging in Patients with DLBCL before and during Anti-CD19 CAR T Cell Therapy

Free
Jaap A. van Doesum, Kylie Keijzer, Janneke W. de Boer, Nienke A.M. Smit, Adrienne H. Brouwers, Marjolijn N. Lub-de Hooge, Frank R. Pierik, Gerwin A. Huls, Lisanne V. van Dijk, Lydia Visser, Arjan Diepstra, Walter Noordzij, Simon P. Williams, Alexander Ungewickell, Sjoerd G. Elias, Elisabeth G.E. de Vries, Anne G.H. Niezink, Tom van Meerten
Journal: Blood
Blood (2024) 144 (Supplement 1): 1037.
https://doi.org/10.1182/blood-2024-199474
Published: 2024
Journal Articles

Real-World Practice Patterns of Patient Management in the Peri-CAR T-Cell Therapy Setting for Patients with Mantle Cell Lymphoma: An International Survey on Behalf of the EBMT Lymphoma Working Party

Free
Gloria Iacoboni, Pere Barba, Irma Khvedelidze, Maud Ngoya, Paolo Corradini, Pierre Sesques, Marion Subklewe, Maria Gomes Da Silva, Gilles Crochet, Jarosław Dybko, Izaskun Zeberio, Alejandro Martín García-Sancho, Tom van Meerten, Maeve O'Reilly, Bertram Glass, Ana Maria Sureda Balari, Peter Dreger, Olivier Hermine, Ali Bazarbachi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3656.
https://doi.org/10.1182/blood-2024-205389
Published: 2024
Journal Articles

Ibrutinib Combined with Venetoclax in Patients with Relapsed/Refractory Mantle Cell Lymphoma: Primary Analysis Results from the Randomized Phase 3 Sympatico Study

Free
Michael Wang, Wojciech Jurczak, Marek Trněný, David Belada, Tomasz Wrobel, Nilanjan Ghosh, Mary-Margaret Keating, Tom van Meerten, Ruben Fernandez Alvarez, Gottfried von Keudell, Catherine Thieblemont, Frederic Peyrade, Marc Andre, Marc Hoffmann, Edith Szafer Glusman, Jennifer Lin, James P. Dean, Jutta K. Neuenburg, Constantine S. Tam
Journal: Blood
Blood (2023) 142 (Supplement 2): LBA-2.
https://doi.org/10.1182/blood-2023-191921
Published: 2023
Journal Articles

Improved Overall Survival with Axicabtagene Ciloleucel Vs Standard of Care in Second-Line Large B-Cell Lymphoma Among the Elderly: A Subgroup Analysis of ZUMA-7

Free
Marie José Kersten, Umar Farooq, Aaron P. Rapoport, Frederick L. Locke, Lori A. Leslie, Armin Ghobadi, David B. Miklos, Caron A. Jacobson, Javier L. Munoz, Patrick B Johnston, Samantha M. Jaglowski, Ian W. Flinn, Tom van Meerten, Miguel-Angel Perales, Peter Vandenberghe, Peter A. Riedell, Kathleen Dorritie, David Szwajcer, Dimitrios Tzachanis, Saran Vardhanabhuti, Linqiu Du, Simone Filosto, Shilpa A. Shahani, Christina To, Jason Westin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1761.
https://doi.org/10.1182/blood-2023-173873
Published: 2023
Journal Articles

Reduction of Metabolic Active Tumor Volume Prior to CAR T-Cell Therapy Improves Survival Outcomes in Patients with Large B-Cell Lymphoma

Free
Kylie Keijzer, Janneke W. de Boer, Jaap A. van Doesum, Walter Noordzij, Gerwin A. Huls, Lisanne V. van Dijk, Tom van Meerten, Anne G.H. Niezink
Journal: Blood
Blood (2023) 142 (Supplement 1): 4380.
https://doi.org/10.1182/blood-2023-173947
Published: 2023
Journal Articles

Patients with Relapsed Large B-Cell Lymphoma after 12 Months Have a Similarly Poor Prognosis As Patients with a Relapse before 12 Months

Free
Hilde T Van Der Galien, Hilde AM Kooistra, Robby Kibbelaar, Nic JGM Veeger, Marcel Nijland, Geert A. Huls, Tom Van Meerten, Rozemarijn S Van Rijn
Journal: Blood
Blood (2023) 142 (Supplement 1): 444.
https://doi.org/10.1182/blood-2023-185993
Published: 2023
Journal Articles

Sickle Cell Disease Patients Mount Adequate Humoral but Reduced Cellular Responses to COVID-19 Vaccination

Free
Cilia R. Pothast, Quincy Hofsink, Sabine Haggenburg, Michel Bhoekhan, Nienke J.E. Haverkate, Romy C. Dijkland, Kayleigh van Dijk, Frederik J.H. Falkenburg, Annoek E.C. Broers, Jaap van Doesum, Robert S. van Binnendijk, Gerco den Hartog, Judith A. Burger, Joey H. Bouhuijs, Birgit I. Lissenberg-Witte, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sonja Zweegman, Arnon P. Kater, Kaz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Tim Beaumont, Marit J. van Gils, Abraham Goorhuis, Mette D. Hazenberg, Inger S. Nijhof, Mirjam H.M. Heemskerk, Caroline E. Rutten
Journal: Blood
Blood (2022) 140 (Supplement 1): 1957–1959.
https://doi.org/10.1182/blood-2022-169164
Published: 2022
Journal Articles

Prophylactic Corticosteroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients (Pts) with Relapsed/Refractory Large B-Cell Lymphoma (R/R LBCL): 2-Year Follow-up of ZUMA-1 Cohort 6

Free
Olalekan O. Oluwole, Edouard Forcade, Javier Muñoz, Sophie de Guibert, Julie M. Vose, Nancy L. Bartlett, Yi Lin, Abhinav Deol, Peter A. McSweeney, Andre H. Goy, Marie José Kersten, Caron A. Jacobson, Umar Farooq, Monique C. Minnema, Catherine Thieblemont, John Timmerman, Patrick Stiff, Irit Avivi, Dimitrios Tzachanis, Yan Zheng, Saran Vardhanabhuti, Jenny Nater, Rhine R. Shen, Harry Miao, Jenny Kim, Tom van Meerten
Journal: Blood
Blood (2022) 140 (Supplement 1): 10399–10401.
https://doi.org/10.1182/blood-2022-156117
Published: 2022
Journal Articles

Discordant Cellular and Humoral Responses to a 3-Dose COVID-19 mRNA Vaccination Schedule in Patients with Hematologic Malignancies

Free
Cilia R. Pothast, Quincy Hofsink, Sabine Haggenburg, Bhoekhan S. Michel, Nienke J.E. Haverkate, Romy C. Dijkland, Kayleigh Van Dijk, Frederik J.H. Falkenburg, Annoek E.C. Broers, Jaap van Doesum, Robert S. Van Binnendijk, Gerco Den Hartog, Judith A. Burger, Joey H. Bouhuijs, Birgit I. Lissenberg-Witte, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sonja Zweegman, Arnon P. Kater, Kaz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Tim Beaumont, Marit J. Van Gils, Abraham Goorhuis, Mette D. Hazenberg, Inger S. Nijhof, Mirjam H.M. Heemskerk, Caroline E. Rutten
Journal: Blood
Blood (2022) 140 (Supplement 1): 8347–8349.
https://doi.org/10.1182/blood-2022-168991
Published: 2022