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Journal Articles

Population-Based External Validation of the CAR-Hematotox Score to Predict CAR T Cell Related Toxicity and Outcome in R/R LBCL Patients

Janneke W. de Boer, Kylie Keijzer, Suzanne van Dorp, Pim G.N.J. Mutsaers, Anne G.H. Niezink, Jaap A. van Doesum, Yasmina I.M. Serroukh, Louise W. Muntendam, Astrid E. Pulles, Esther J. Kret, Aniko Sijs-Szabo, Jesse Oomen, Astrid M.P. Demandt, Wendy B.C. Stevens, Maria T. Kuipers, Elise R.A. Pennings, Anne M. Spanjaart, Marie José Kersten, Margot Jak, Lisanne V. van Dijk, Marjolein W.M. van der Poel, Joost S.P. Vermaat, Tom van Meerten
Journal: Blood
Blood (2024) 144 (Supplement 1): 1747.
https://doi.org/10.1182/blood-2024-209879
Published: 2024
Journal Articles

Prediction of Poor Outcome after Tisagenlecleucel in Patients with Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL) Using Artificial Intelligence Analysis of Pre-Infusion PET/CT

Margot Jak, Bas H.M. van der Velden, Bart de Keizer, Sjoerd G Elias, Monique C. Minnema, Kenneth G.A. Gilhuijs
Journal: Blood
Blood (2022) 140 (Supplement 1): 1919–1920.
https://doi.org/10.1182/blood-2022-158543
Published: 2022
Journal Articles

In Vitro Model to Predict Response to Daratumumab Therapy in Relapsed/Refractory Multiple Myeloma

Niels Van Nieuwenhuijzen, Marta Cuenca, Leonie Abbink, Eline Lammers, Margot Jak, Victor Peperzak, Monique C. Minnema
Journal: Blood
Blood (2021) 138 (Supplement 1): 1568.
https://doi.org/10.1182/blood-2021-146513
Published: 2021
Journal Articles

IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells

Maria Fernanda Pascutti, Margot Jak, Jacqueline M. Tromp, Ingrid A. M. Derks, Ester B. M. Remmerswaal, Rachel Thijssen, Martijn H. A. van Attekum, Gregor G. van Bochove, Dieuwertje M. Luijks, Steven T. Pals, René A. W. van Lier, Arnon P. Kater, Marinus H. J. van Oers, Eric Eldering
Journal: Blood
Blood (2013) 122 (17): 3010–3019.
https://doi.org/10.1182/blood-2012-11-467670
Published: 2013
Includes: Supplemental data
Journal Articles

Role of T Cell-Derived IL-21 in the Proliferation of Chronic Lymphocytic Leukemia Cells,

Maria F. Pascutti, PhD, Jacqueline M. Tromp, MD, Margot Jak, MD, Ingrid A.M. Derks, Rene A.W. van Lier, PhD, Steven T. Pals, MD, PhD, Marinus H.J. Van Oers, MD, PhD, Arnon P Kater, MD, PhD, Eric Eldering, PhD
Journal: Blood
Blood (2011) 118 (21): 3871.
https://doi.org/10.1182/blood.V118.21.3871.3871
Published: 2011
Journal Articles

CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101

Margot Jak, Gregor G. W. van Bochove, Eric A. Reits, Wouter W. Kallemeijn, Jacqueline M. Tromp, Pablo Umana, Christian Klein, Rene A. W. van Lier, Marinus H. J. van Oers, Eric Eldering
Journal: Blood
Blood (2011) 118 (19): 5178–5188.
https://doi.org/10.1182/blood-2011-01-331702
Published: 2011
Includes: Supplemental data
Journal Articles

CD40 Stimulation Sensitizes CLL Cells to CD20-Triggered Cell Death by Rituximab and GA101 Via a Different Mechanism

Margot Jak, Gregor van Bochove, Christian Klein, PhD, Pablo Umana, PhD, Eric Eldering, PhD, Marinus H.J. Van Oers, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3979.
https://doi.org/10.1182/blood.V116.21.3979.3979
Published: 2010
Journal Articles

Enhanced Formation and Survival of Regulatory T Cells in CLL.

Margot Jak, Rogier Mous, Ester BM Remmerswaal, René Spijker, Annelieke Jaspers, Adriana Yagüe, Eric Eldering, René A.W. van Lier, Marinus H. J. van Oers
Journal: Blood
Blood (2008) 112 (11): 1065.
https://doi.org/10.1182/blood.V112.11.1065.1065
Published: 2008
Journal Articles

Attacking Oncogene Addiction in B-CLL: Seliciclib First Engages the Mcl-1/Noxa Axis, after Which Gradual Exhaustion of Bcl-2 Protection Leads to Bax Activation.

Delfine Y.H. Hallaert, Rene Spijker, Margot Jak, Annelieke Jaspers, Ingrid A.M. Derks, Nuno L. Alves, Drs, Jan Paul de Boer, Daphne de Jong, MD, Simon R. Green, Rene A.W. van Lier, MD, PhD, Marinus H.J. van Oers, MD, PhD, Eric Eldering, PhD
Journal: Blood
Blood (2006) 108 (11): 2103.
https://doi.org/10.1182/blood.V108.11.2103.2103
Published: 2006
Journal Articles

The Novel Cancer Drug Seliciclib Engages the Mitochondrial Apoptosis Pathway Via the Mcl-1/Noxa Axis in CLL.

Delfine Hallaert, Rene Spijker, Ingrid A.M. Derks, Margot Jak, MD, Bart de Goeij, Jan Paul de Boer, MD, PhD, Daphne de Jong, MD, PhD, Simon R. Green, Rene van Lier, MD, PhD, Eric Eldering, PhD, Marinus H.J. Van Oers, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2983.
https://doi.org/10.1182/blood.V106.11.2983.2983
Published: 2005