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Journal Articles

Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma

Clinical Trials & Observations
F. Smits, Kaz Groen, Mark-David Levin, Claudia Stege, Roel J.W. van Kampen, Ellen van der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C. Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane MB Vekemans, Nazik Durdu-Rayman, Nicole C.H.P. de Graauw, Maarten R. Seefat, Niels W.C.J. van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood blood.2024025868.
https://doi.org/10.1182/blood.2024025868
Published: 2024
Includes: Supplemental data
Journal Articles

Dynamics of Geriatric Impairments Are Associated with Risk of Treatment Discontinuation in Elderly Patients with Multiple Myeloma

Febe Smits, Kazem Nasserinejad, Mark-David Levin, Gert Jan Timmers, Esther G.M. De Waal, Josien C Regelink, Gerjo A. Velders, Matthijs Westerman, Nazik Durdu-Rayman, Suzanne Last-Koopmans, Roel JW van Kampen, Claudia A M Stege, Kaz Groen, Maarten R. Seefat, Monique C. Minnema, Pieter Sonneveld, Paula F Ypma, Niels W.C.J. van de Donk, Sonja Zweegman
Journal: Blood
Blood (2024) 144 (Supplement 1): 3330.
https://doi.org/10.1182/blood-2024-203477
Published: 2024
Journal Articles

Long-Term Follow-up from the Phase 2 ICON Study of Iberdomide Combined with Low-Dose Cyclophosphamide and Dexamethasone in Relapsed/Refractory Multiple Myeloma (IberCd)

Charlotte L.B.M. Korst, Wouter Plattel, Elizabeth de Kort, Alexandra Croockewit, Mark-David Levin, Matthijs Westerman, Okke De Weerdt, Inger S. Nijhof, Jurgen Wegman, Nina Smit, Christie P.M. Verkleij, Tuna Mutis, Marjolein van der Klift, Laurens Franssen, Kaz Groen, Ellen van der Spek, Wilfried Roeloffzen, Sonja Zweegman, Niels W.C.J. van de Donk
Journal: Blood
Blood (2024) 144 (Supplement 1): 3371.
https://doi.org/10.1182/blood-2024-200187
Published: 2024
Journal Articles

Frailty Subgroups Determine Heterogeneous Outcomes in Elderly Patients with Newly-Diagnosed Multiple Myeloma - Long-Term Follow-up of the HOVON 143 Trial

Febe Smits, Kaz Groen, Mark-David Levin, Claudia A M Stege, Roel JW van Kampen, Ellen Van Der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. De Waal, Yorick Sandberg, Alain Kentos, Gert Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie Christiane Vekemans, Nazik Durdu-Rayman, Nicole de Graauw, Maarten R. Seefat, Niels W.C.J. van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4739.
https://doi.org/10.1182/blood-2024-208754
Published: 2024
Journal Articles

CD16, CD57 and DNAM-1 Positive NK Cells Predict MRD Negativity in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Bortezomib, Thalidomide and Dexamethasone

Charlotte L.B.M. Korst, Carolien Duetz, Wassilis S.C Bruins, A. Vera de Jonge, Kaz Groen, Christie P.M. Verkleij, Kristine A. Frerichs, Meliha Cosovic, Inoka Twickler, Rosa Rentenaar, Merve Eken, Paola Homan-Weert, Philippe Moreau, Pieter Sonneveld, Sonja Zweegman, Tuna Mutis, Niels W.C.J. Van De Donk
Journal: Blood
Blood (2023) 142 (Supplement 1): 3314.
https://doi.org/10.1182/blood-2023-177560
Published: 2023
Journal Articles

Baseline CD57 + and CD16 + NK-Cells Predict Treatment Outcome in Non-Transplant Eligible Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab-Ixazomib-Dexamethasone

Wassilis S.C Bruins, Carolien Duetz, Kaz Groen, Charlotte L.B.M. Korst, A.Vera de Jonge, Rosa Rentenaar, Meliha Cosovic, Merve Eken, Inoka Twickler, Paola Homan-Weert, Christie P.M. Verkleij, Kristine A. Frerichs, Niels WCJ van de Donk, Sonja Zweegman, Tuna Mutis
Journal: Blood
Blood (2023) 142 (Supplement 1): 1940.
https://doi.org/10.1182/blood-2023-189527
Published: 2023
Journal Articles

Dynamic Frailty Status Enables Better Prediction of Survival Probability - Results of the HOVON 143 Study

Febe Smits, Kaz Groen, Mark-David Levin, Claudia Stege, Roel JW Van Kampen, Ellen Van Der Spek, Yavuz M Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. De Waal, Yorick Sandberg, Alain Kentos, Gert Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie Christiane Vekemans, Nazik Durdu-Rayman, Nicole de Graauw, Maarten R. Seefat, Niels WCJ van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2023) 142 (Supplement 1): 342.
https://doi.org/10.1182/blood-2023-180006
Published: 2023
Journal Articles

Discordant Cellular and Humoral Responses to a 3-Dose COVID-19 mRNA Vaccination Schedule in Patients with Hematologic Malignancies

Cilia R. Pothast, Quincy Hofsink, Sabine Haggenburg, Bhoekhan S. Michel, Nienke J.E. Haverkate, Romy C. Dijkland, Kayleigh Van Dijk, Frederik J.H. Falkenburg, Annoek E.C. Broers, Jaap van Doesum, Robert S. Van Binnendijk, Gerco Den Hartog, Judith A. Burger, Joey H. Bouhuijs, Birgit I. Lissenberg-Witte, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sonja Zweegman, Arnon P. Kater, Kaz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Tim Beaumont, Marit J. Van Gils, Abraham Goorhuis, Mette D. Hazenberg, Inger S. Nijhof, Mirjam H.M. Heemskerk, Caroline E. Rutten
Journal: Blood
Blood (2022) 140 (Supplement 1): 8347–8349.
https://doi.org/10.1182/blood-2022-168991
Published: 2022
Journal Articles

Sickle Cell Disease Patients Mount Adequate Humoral but Reduced Cellular Responses to COVID-19 Vaccination

Cilia R. Pothast, Quincy Hofsink, Sabine Haggenburg, Michel Bhoekhan, Nienke J.E. Haverkate, Romy C. Dijkland, Kayleigh van Dijk, Frederik J.H. Falkenburg, Annoek E.C. Broers, Jaap van Doesum, Robert S. van Binnendijk, Gerco den Hartog, Judith A. Burger, Joey H. Bouhuijs, Birgit I. Lissenberg-Witte, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sonja Zweegman, Arnon P. Kater, Kaz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Tim Beaumont, Marit J. van Gils, Abraham Goorhuis, Mette D. Hazenberg, Inger S. Nijhof, Mirjam H.M. Heemskerk, Caroline E. Rutten
Journal: Blood
Blood (2022) 140 (Supplement 1): 1957–1959.
https://doi.org/10.1182/blood-2022-169164
Published: 2022
Journal Articles

Ixazomib, Daratumumab and Low Dose Dexamethasone in Intermediate-Fit Patients with Newly Diagnosed Multiple Myeloma (NDMM); Results of Induction Treatment of the Phase II HOVON 143 Study

Kaz Groen, Claudia A.M. Stege, Kazem Nasserinejad, Koen de Heer, Roel J.W. Van Kampen, Maria B.L. Leijs, Noortje Thielen, Matthijs Westerman, Ka Lung Wu, Inge Ludwig, Djamila Issa, Gerjo A. Velders, Marie-Christiane Vekemans, Niels W.C.J. van de Donk, Gert-Jan Timmers, Pieter Sonneveld, Maarten R. Seefat, Fransien Croon-de Boer, Lidwine W. Tick, Ellen van der Spek, Esther G.M. De Waal, Maaike Sohne, Paula F Ypma, Inger S. Nijhof, Saskia K. Klein, Mark-David Levin, Sonja Zweegman
Journal: Blood
Blood (2021) 138 (Supplement 1): 80.
https://doi.org/10.1182/blood-2021-152112
Published: 2021