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Matthijs Westerman
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Journal Articles

Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma

Clinical Trials & Observations
F. Smits, Kaz Groen, Mark-David Levin, Claudia Stege, Roel J.W. van Kampen, Ellen van der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. de Waal, Yorick Sandberg, Alain Kentos, Gert-Jan Timmers, Josien C. Regelink, Matthijs Westerman, Koen de Heer, Marie-Christiane MB Vekemans, Nazik Durdu-Rayman, Nicole C.H.P. de Graauw, Maarten R. Seefat, Niels W.C.J. van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood blood.2024025868.
https://doi.org/10.1182/blood.2024025868
Published: 2024
Includes: Supplemental data
Journal Articles

Long-Term Follow-up from the Phase 2 ICON Study of Iberdomide Combined with Low-Dose Cyclophosphamide and Dexamethasone in Relapsed/Refractory Multiple Myeloma (IberCd)

Charlotte L.B.M. Korst, Wouter Plattel, Elizabeth de Kort, Alexandra Croockewit, Mark-David Levin, Matthijs Westerman, Okke De Weerdt, Inger S. Nijhof, Jurgen Wegman, Nina Smit, Christie P.M. Verkleij, Tuna Mutis, Marjolein van der Klift, Laurens Franssen, Kaz Groen, Ellen van der Spek, Wilfried Roeloffzen, Sonja Zweegman, Niels W.C.J. van de Donk
Journal: Blood
Blood (2024) 144 (Supplement 1): 3371.
https://doi.org/10.1182/blood-2024-200187
Published: 2024
Journal Articles

Dynamics of Geriatric Impairments Are Associated with Risk of Treatment Discontinuation in Elderly Patients with Multiple Myeloma

Febe Smits, Kazem Nasserinejad, Mark-David Levin, Gert Jan Timmers, Esther G.M. De Waal, Josien C Regelink, Gerjo A. Velders, Matthijs Westerman, Nazik Durdu-Rayman, Suzanne Last-Koopmans, Roel JW van Kampen, Claudia A M Stege, Kaz Groen, Maarten R. Seefat, Monique C. Minnema, Pieter Sonneveld, Paula F Ypma, Niels W.C.J. van de Donk, Sonja Zweegman
Journal: Blood
Blood (2024) 144 (Supplement 1): 3330.
https://doi.org/10.1182/blood-2024-203477
Published: 2024
Journal Articles

Frailty Subgroups Determine Heterogeneous Outcomes in Elderly Patients with Newly-Diagnosed Multiple Myeloma - Long-Term Follow-up of the HOVON 143 Trial

Febe Smits, Kaz Groen, Mark-David Levin, Claudia A M Stege, Roel JW van Kampen, Ellen Van Der Spek, Yavuz M. Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. De Waal, Yorick Sandberg, Alain Kentos, Gert Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie Christiane Vekemans, Nazik Durdu-Rayman, Nicole de Graauw, Maarten R. Seefat, Niels W.C.J. van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4739.
https://doi.org/10.1182/blood-2024-208754
Published: 2024
Journal Articles

Dynamic Frailty Status Enables Better Prediction of Survival Probability - Results of the HOVON 143 Study

Febe Smits, Kaz Groen, Mark-David Levin, Claudia Stege, Roel JW Van Kampen, Ellen Van Der Spek, Yavuz M Bilgin, Noortje Thielen, Inger S. Nijhof, Inge Ludwig, Esther G.M. De Waal, Yorick Sandberg, Alain Kentos, Gert Jan Timmers, Josien C Regelink, Matthijs Westerman, Koen de Heer, Marie Christiane Vekemans, Nazik Durdu-Rayman, Nicole de Graauw, Maarten R. Seefat, Niels WCJ van de Donk, Paula F Ypma, Kazem Nasserinejad, Sonja Zweegman
Journal: Blood
Blood (2023) 142 (Supplement 1): 342.
https://doi.org/10.1182/blood-2023-180006
Published: 2023
Journal Articles

Ixazomib, Daratumumab and Low Dose Dexamethasone in Intermediate-Fit Patients with Newly Diagnosed Multiple Myeloma (NDMM); Results of Induction Treatment of the Phase II HOVON 143 Study

Kaz Groen, Claudia A.M. Stege, Kazem Nasserinejad, Koen de Heer, Roel J.W. Van Kampen, Maria B.L. Leijs, Noortje Thielen, Matthijs Westerman, Ka Lung Wu, Inge Ludwig, Djamila Issa, Gerjo A. Velders, Marie-Christiane Vekemans, Niels W.C.J. van de Donk, Gert-Jan Timmers, Pieter Sonneveld, Maarten R. Seefat, Fransien Croon-de Boer, Lidwine W. Tick, Ellen van der Spek, Esther G.M. De Waal, Maaike Sohne, Paula F Ypma, Inger S. Nijhof, Saskia K. Klein, Mark-David Levin, Sonja Zweegman
Journal: Blood
Blood (2021) 138 (Supplement 1): 80.
https://doi.org/10.1182/blood-2021-152112
Published: 2021
Journal Articles

Efficacy and Tolerability of Ixazomib, Daratumumab and Low Dose Dexamethasone (Ixa Dara dex) in Unfit and Frail Newly Diagnosed Multiple Myeloma (NDMM) Patients; Results of the Interim Efficacy Analysis of the Phase II HOVON 143 Study

Claudia A.M. Stege, MD, Kazem Nasserinejad, Ellen van der Spek, MD PhD, Roel J.W. Van Kampen, MD PhD, Maaike Sohne, MD, Noortje Thielen, MD PhD, Yavuz Bilgin, MD PhD, Esther G.M. De Waal, MD, Inge Ludwig, MD MSc, Maria B.L. Leijs, MD, Alain Kentos, MD, Gert Jan Timmers, MD PhD, Koen de Heer, MD, Matthijs Westerman, MD, Marie Christiane Vekemans, Nazik Durdu-Rayman, MD, Nicole C.H.P. van der Burg-de Graauw, MD, Niels W. C. J. Van De Donk, MD PhD, Pieter Sonneveld, Saskia K. Klein, MD PhD, Mark-David Levin, MD PhD, Sonja Zweegman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 695.
https://doi.org/10.1182/blood-2019-121694
Published: 2019
Journal Articles

Efficacy and Tolerability of Ixazomib, Daratumumab and Low Dose Dexamethasone (IDd) in Unfit and Frail Newly Diagnosed Multiple Myeloma (NDMM) Patients; First Interim Safety Analysis of the Phase II HOVON 143 Study

Claudia A.M. Stege, MD, Kazem Nasserinejad, PhD, Mark-David Levin, MDPhD, Noortje Thielen, MD PhD, Saskia K. Klein, MD PhD, Inge Ludwig, MD MSc, Matthijs Westerman, MD, Paula F Ypma, MDPhD, Yavuz Bilgin, MDPhD, Maaike Sohne, MD, Esther de Waal, PhD, Niels WCJ van de Donk, MD PhD, Pieter Sonneveld, MDPhD, Sonja Zweegman, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 596.
https://doi.org/10.1182/blood-2018-99-114668
Published: 2018
Journal Articles

Geriatric Impairments and Low Muscle Mass Are Associated with Treatment Discontinuation and Overall Survival in Newly Diagnosed Non-Transplant Eligible Multiple Myeloma Patients (nte-NDMM) Treated with Dose-Adjusted Melphalan-Prednisone-Bortezomib (MPV) — Results of the Dutch HOVON 123 Study

Claudia A.M. Stege, MD, Kazem Nasserinejad, PhD, Mark-David Levin, MDPhD, Saskia K. Klein, MD PhD, Esther de Waal, PhD, Corien Eeltink, Charlotte L.B.M. Korst, MD, Paula F Ypma, MDPhD, Amanda C. Dijk, MD, Matthijs Westerman, MD, Wendy Deenik, MD, Bea Tanis, PhD, Monique C Minnema, MD PhD, Henk M.W. Verheul, MD PhD, Birgit I. Lissenberg-Witte, PhD, Niels WCJ van de Donk, MD PhD, Pieter Sonneveld, MD PhD, Sonja Zweegman, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1889.
https://doi.org/10.1182/blood-2018-99-116920
Published: 2018
Journal Articles

Frailty Predicts Survival and Toxicity in Newly Diagnosed Multiple Myeloma Patients Ineligible for Autologous Stem Cell Transplantation; Report of the HOVON-87/Nmsg-18 Study Group

Claudia A.M. Stege, MD, Bronno van der Holt, Ulf-Henrik Mellqvist, MD, Mark-David Levin, PhD, Morten Salomo, Niels Abildgaard, MD, Gerard Bos, MDPhD, Heleen Visser-Wisselaar, Markus Hansson, MD PhD, Annette van der Velden, MD, Wendy Deenik, MD, Astrid Gruber, MD PhD, Jules L.L.M. Coenen, MD, Torben Plesner, MD, Saskia Klein, MD, Bea Tanis, MD PhD, Damian L. Szatkowski, MDPhDMSc, Rolf Brouwer, MD PhD, Matthijs Westerman, MD, Maria Berhardina Leijs, MD, Harm Sinnige, Einar Haukaas, Klaas van der Hem, MD PhD, Marc Durian, MD, Vera Mattijssen, MD PhD, Peter Gimsing, DO, PhD, Niels WCJ Van De Donk, Marian Stevens-Kroef, PhD, Pieter Sonneveld, MDPhD, Anders Waage, MD PhD, Sonja Zweegman, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3146.
https://doi.org/10.1182/blood.V130.Suppl_1.3146.3146
Published: 2017
Journal Articles

Feasibility and Efficacy of Dose Adjusted Melphalan - Prednisone - Bortezomib (MPV) in Elderly Patients ≥ 75 Years of Age with Newly Diagnosed Multiple Myeloma; the Non-Randomised Phase II HOVON 123 Study

Sonja Zweegman, MD PhD, Mark-David Levin, MD PhD, Saskia K. Klein, MD PhD, Esther G.M. De Waal, MD, Corien M. Eeltink, RN, MA, ANP, Paula F. Ypma, MD, Amanda C. Dijk, MD, Matthijs Westerman, MD, Wendy Deenik, MD PhD, Bea Tanis, MD PhD, Monique S. Slee-Valentijn, MD, Monique Minnema, Heleen Visser-Wisselaar, PhD, Claudia Stege, MD, Niels W.C.J. van de Donk, MD PhD, Kazem Nasserinejad, MA, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3305.
https://doi.org/10.1182/blood.V128.22.3305.3305
Published: 2016
Journal Articles

Melphalan, prednisone, and lenalidomide versus melphalan, prednisone, and thalidomide in untreated multiple myeloma

Clinical Trials & Observations
Sonja Zweegman, Bronno van der Holt, Ulf-Henrik Mellqvist, Morten Salomo, Gerard M. J. Bos, Mark-David Levin, Heleen Visser-Wisselaar, Markus Hansson, Annette W. G. van der Velden, Wendy Deenik, Astrid Gruber, Juleon L. L. M. Coenen, Torben Plesner, Saskia K. Klein, Bea C. Tanis, Damian L. Szatkowski, Rolf E. Brouwer, Matthijs Westerman, M. (Rineke) B. L. Leys, Harm A. M. Sinnige, Einar Haukås, Klaas G. van der Hem, Marc F. Durian, E. (Vera) J. M. Mattijssen, Niels W. C. J. van de Donk, Marian J. P. L. Stevens-Kroef, Pieter Sonneveld, Anders Waage
Journal: Blood
Blood (2016) 127 (9): 1109–1116.
https://doi.org/10.1182/blood-2015-11-679415
Published: 2016
Includes: Supplemental data
Journal Articles

Randomized Phase III Trial in Non-Transplant Eligible Patients with Newly Diagnosed Symptomatic Multiple Myeloma Comparing Melphalan-Prednisone-Thalidomide Followed By Thalidomide Maintenance (MPT-T) Versus Melphalan-Prednisone-Lenalidomide Followed By Maintenance with Lenalidomide (MPR-R); A Joint Study of the Dutch-Belgian Cooperative Trial Group for Hematology Oncology (HOVON) and the Nordic Myeloma Study Group (NMSG)

Sonja Zweegman, MDPhD, Bronno van der Holt, PhD, Ulf-Henrik Mellqvist, MDPhD, Morten Salomo, MD, Gerard M.J. Bos, MDPhD, Mark-David Levin, MDPhD, Heleen A Visser-Wisselaar, PhD, Markus Hansson, MD PhD, Annette WG van der Velden, MD, Wendy Deenik, MDPhD, Astrid Gruber, MDPhD, Juleon LLM Coenen, MD, Torben Plesner, MD, Saskia K Klein, MDPhD, Bea Tanis, MDPhD, Damian L Szatkowski, MDPhDMSc, Rolf Brouwer, MDPhD, Matthijs Westerman, MD, M (Rineke) BL Leys, MDPhD, Niels W.C.J. van de Donk, MDPhD, Einar Haukås, MD, Klaas van der Hem, MD PhD, MF Durian, MD, E (Vera) JM Mattijssen, MDPhD, Harm AM Sinnige, MDPhD, Marian JPL Stevens-Kroef, PhD, Pieter Sonneveld, MDPhD, Anders Waage, MD PhD
Journal: Blood
Blood (2014) 124 (21): 179.
https://doi.org/10.1182/blood.V124.21.179.179
Published: 2014