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Claire Roddie
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Journal Articles

Obecabtagene autoleucel (obe-cel) for Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL): Deep Molecular Remission May Predict Better Outcomes

Elias Jabbour, Jae H. Park, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Pierre Lao-Sirieix, Wolfram Brugger, Martin A Pule, Yiyun Zhang, Claire Roddie
Journal: Blood
Blood (2024) 144 (Supplement 1): 963.
https://doi.org/10.1182/blood-2024-194508
Published: 2024
Journal Articles

Site-Specific Analysis of Extranodal Involvement Reveals Distinct Efficacy Outcomes with CAR T-Cell Therapy in Large B-Cell Lymphoma Patients

Gloria Iacoboni, Kai Rejeski, Victor Navarro Garces, Tom van Meerten, Alex Rampotas, Ana Africa Martin Lopez, Juan Luis Reguera, Mariana Bastos-Oreiro, Claire Roddie, Ana Benzaquen, Cecilia Carpio, Javier Delgado Serrano, Maria Landwehr, Sophia Stock, Pablo Silva De Tena, Pau Abrisqueta Costa, Janneke W. De Boer, Lucia Lopez Corral, Rafael Hernani, Marion Subklewe, Mi Kwon, Maeve O'Reilly, Pere Barba
Journal: Blood
Blood (2024) 144 (Supplement 1): 471.
https://doi.org/10.1182/blood-2024-205809
Published: 2024
Journal Articles

Bridging Pediatric B-Cell Acute Lymphoblastic Leukemia (ALL) Patients to CAR-T Cell Therapy: A National Perspective

Gustavo De Oliveira Canedo, Macarena Oporto Espuelas, Saskia Burridge, Priti Mehta, Orpheas Iosifidis, Denise Bonney, Kelly Watts, Geoff Shenton, Katarzyna Jalowiec, Maeve O'Reilly, Claire Roddie, Katherine Clesham, Jack Bartram, Robert Chiesa, Giovanna Lucchini, Vesna Pavasovic, Anupama Rao, Kanchan Rao, Juliana Silva, Sujith Samarasinghe, Ajay Vora, David Marks, Persis Jal Amrolia, Rachael Hough, Sara Ghorashian
Journal: Blood
Blood (2024) 144 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2024-200239
Published: 2024
Journal Articles

Multi-Centre Real-World Outcomes of Large B-Cell Lymphoma Patients Treated with 2L Axicabtagene Ciloleucel in the UK

Andrea Kuhnl, Amy A Kirkwood, Claire Roddie, Caroline Besley, Jane Norman, Ben Uttenthal, Frances Seymour, Andrew J. Davies, Wendy Osborne, William Townsend, Emil Arjun Kumar, Amrith Mathew, Carlos Gonzalez Arias, Ceri Jones, Aikaterini Panopoulou, Ahmed Abdulgawad, Edward Bataillard, Pierre McCarthy, Nicolas Martinez-Calle, Vaishali Dulobdas, Rajesh Alajangi, Ram Malladi, Muddeha Waraich, Olateni Awofisayo, Hwai Jing Hiew, Callum Harris, Michael Northend, Adrian Maraj, Shankaranarayana Paneesha, Kasys Meira-Gervatauskas, Kate Cwynarski, Graham P. Collins, Roderick J. Johnson, Robin Sanderson, Maeve O'Reilly, Tobias Menne, Sridhar Chaganti
Journal: Blood
Blood (2024) 144 (Supplement 1): 2342.
https://doi.org/10.1182/blood-2024-200738
Published: 2024
Journal Articles

Risk Factors Associated with Sub-Optimal Outcomes Following Obecabtagene autoleucel (obe-cel) for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL): What We Have Learned from the FELIX Trial

Claire Roddie, Jae H. Park, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Wolfram Brugger, Martin A Pule, Justin Shang, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4845.
https://doi.org/10.1182/blood-2024-208028
Published: 2024
Journal Articles

Healthcare Resource Utilization and Costs Associated with Managing CRS and ICANS in Patients with Relapsed/Refractory Adult B-Cell Acute Lymphoblastic Leukemia Receiving Obecabtagene autoleucel (obe-cel)

Bijal D Shah, Jeremy Pantin, Karamjeet S Sandhu, Elias Jabbour, Jae H. Park, Paul Shaughnessy, Mehrdad Abedi, Michael R Bishop, Daniel J. DeAngelo, Wolfram Brugger, Martin Brown, Dilip Patel, Claire Roddie, Aaron C. Logan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4837.
https://doi.org/10.1182/blood-2024-205694
Published: 2024
Journal Articles

Cohort Comparison of Therapy-Related Myeloid Neoplasms after CAR T-Cell Therapy, Autologous Stem Cell Transplant, and Standard Cancer Therapies

Jaime Roman Diaz, Saurabh Dahiya, Francesca Emily Sillito, Maeve O'Reilly, Kai Rejeski, Veit L. Buecklein, Marion Subklewe, Gloria Iacoboni, Pere Barba, Claire Roddie, Frederick Locke, Jay Y. Spiegel, Najla H. Al Ali, Zachary Thompson, Jongphil Kim, Rami S. Komrokji, Michael D. Jain
Journal: Blood
Blood (2024) 144 (Supplement 1): 7239.
https://doi.org/10.1182/blood-2024-201666
Published: 2024
Journal Articles

Obecabtagene autoleucel (obe-cel) for Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL) in the Open-Label, Multi-Center, Global, Single-Arm, Phase Ib/II FELIX Study: The Impact of Bridging Therapies on CAR T-Cell Expansion and Persistence

Jae H. Park, Elias Jabbour, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Pierre Lao-Sirieix, Wolfram Brugger, Martin A Pule, Justin Shang, Claire Roddie
Journal: Blood
Blood (2024) 144 (Supplement 1): 3458.
https://doi.org/10.1182/blood-2024-201514
Published: 2024
Journal Articles

Development of a First-in-Class CAR-T Therapy Against Calreticulin-Mutant Neoplasms and Evaluation in the Relevant Human Tissue Environment

Alexandros Rampotas, Zoe Wong, Isaac Gannon, Camelia Benlabiod, Yuqi Shen, Charlotte Brierley, Aude-Anais Olijnik, Saif Khan, Nawshad Hayder, Gordon Weng-Kit Cheung, Marina Mitsikakou, Manuel Rodriguez-Justo, Abdullah O Khan, Adam J Mead, Jonathan Lambert, Claire Roddie, Bethan Psaila, Martin A Pule
Journal: Blood
Blood (2024) 144 (Supplement 1): 871.
https://doi.org/10.1182/blood-2024-204953
Published: 2024
Journal Articles

The present and future for CAR-T cell therapy in adult B-cell ALL

Claire Roddie, Alexandros Rampotas
Journal: Blood
Blood blood.2023022922.
https://doi.org/10.1182/blood.2023022922
Published: 2024
Journal Articles

Development of a Phase 1 Study Evaluating the Activity of Modular CAR T for Multiple Myeloma (MCARTY) Targeting BCMA and CD19 for Improved Persistence

Lydia Sarah Hui Lee, Wen Chean Lim, Catriona Mactier, Juliana Dias Alves Pinto, Vitoria Pereira, Mhairi Vaughan, Louisa Green, Evie Lewin, John Garcia, Giulia Agliardi, Yashma Pathak, Riaz Jannoo, Leigh Wood, Bilyana Popova, Helen Holmes, Simon Thomas, Victoria Spanswick, William Wilson, Christopher Parrish, Rakesh Popat, Claire Roddie, Kwee Yong, Martin A. Pule
Journal: Blood
Blood (2023) 142 (Supplement 1): 350.
https://doi.org/10.1182/blood-2023-185085
Published: 2023
Journal Articles

Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Claire Roddie, Karamjeet S. Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Michael R. Bishop, Jean A. Yared, Armin Ghobadi, Deborah Yallop, Aaron C. Logan, Amer M. Beitinjaneh, Jeremy M. Pantin, Martha Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla Gómez, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen M. O'Dwyer, Sameem Abedin, Hassan Alkhateeb, Bijal D. Shah, Pierre Lao-Sirieix, Gianfranco Pittari, Kapil Saxena, Yiyun Zhang, Wolfram Brugger, Martin A. Pule, Jae H. Park, Daniel J. DeAngelo, Elias Jabbour
Journal: Blood
Blood (2023) 142 (Supplement 1): 222.
https://doi.org/10.1182/blood-2023-179454
Published: 2023
Journal Articles

Long-Term Efficacy and Safety of Obecabtagene Autoleucel (obe-cel) in Adult Patients (pts) with Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia ([R/R B-ALL]; Pooled Analysis from ALLCAR19 and FELIX Phase Ib Studies) or Other B-cell Malignancies (ALLCAR19 Extension Study)

Claire Roddie, Eleni Tholouli, Paul Shaughnessy, Elias Jabbour, Aaron C. Logan, Katharine Hodby, Luke Mountjoy, Adrian John Clifton Bloor, David Irvine, David C. Linch, Kim H. Orchard, William Wilson, Bilyana Popova, Juliana Dias, Giulia Agliardi, Victoria Spanswick, Helen Lowe, Marina Mitsikakou, Eftychia Charalambous, Joanna Dawes, Meera Raymond, Yanqing Hu, Wolfram Brugger, Martin A. Pule, Jae H. Park, Karl Peggs
Journal: Blood
Blood (2023) 142 (Supplement 1): 2114.
https://doi.org/10.1182/blood-2023-180666
Published: 2023
Journal Articles

Immune effector cell–associated hematotoxicity: EHA/EBMT consensus grading and best practice recommendations

Kai Rejeski, Marion Subklewe, Mahmoud Aljurf, Emmanuel Bachy, Adriana Balduzzi, Pere Barba, Benedetto Bruno, Reuben Benjamin, Matteo G. Carrabba, Christian Chabannon, Fabio Ciceri, Paolo Corradini, Julio Delgado, Roberta Di Blasi, Raffaella Greco, Roch Houot, Gloria Iacoboni, Ulrich Jäger, Marie José Kersten, Stephan Mielke, Arnon Nagler, Francesco Onida, Zinaida Peric, Claire Roddie, Annalisa Ruggeri, Fermín Sánchez-Guijo, Isabel Sánchez-Ortega, Dominik Schneidawind, Maria-Luisa Schubert, John A. Snowden, Catherine Thieblemont, Max Topp, Pier Luigi Zinzani, John G. Gribben, Chiara Bonini, Anna Sureda, Ibrahim Yakoub-Agha
Journal: Blood
Blood (2023) 142 (10): 865–877.
https://doi.org/10.1182/blood.2023020578
Published: 2023
Includes: Supplemental data
Journal Articles

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma

Clinical Trials & Observations
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G. R. Peddareddigari, Nushmia Khokhar, Robert Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve A. O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin A. Pule
Journal: Blood
Blood (2023) 141 (20): 2470–2482.
https://doi.org/10.1182/blood.2022018598
Published: 2023
Includes: Supplemental data
Journal Articles

Brexucabtagene Autoleucel for Relapsed/Refractory Mantle Cell Lymphoma: Real-World Outcomes in the United Kingdom

Maeve A O'Reilly, Robin Sanderson, William Wilson, David Burns, Caroline Besley, Thomas Creasey, Ben Uttenthal, Johnathon Elliot, Claire Roddie, Andrea Kuhnl, Shankara Paneesha, Frances Seymour, Sunil Iyengar, Lourdes Rubio, Matthew Wilson, Stephen Boyle, Kathleen PL Cheok, Graham P. Collins, Rod Johnson, Andrew K. McMillan
Journal: Blood
Blood (2022) 140 (Supplement 1): 7519–7521.
https://doi.org/10.1182/blood-2022-165031
Published: 2022
Journal Articles

Recent Bendamustine Treatment before Apheresis Has a Negative Impact on Outcomes in Patients with Large B-Cell Lymphoma Receiving Chimeric Antigen Receptor T-Cell Therapy

Gloria Iacoboni, ANA Africa Martin Lopez, Katarzyna Aleksandra Jalowiec, Mi Kwon, Kai Rejeski, Víctor Navarro Garcés, Paula Amat, Juan Luis Reguera, Laura Gallur, Sara Gutierrez-Herrero, Claire Roddie, Gillen Oarbeascoa, Ana Benzaquén, Cecilia Carpio, Lucía López Corral, Rafael Hernani, Mariana Bastos-Oreiro, Marion Subklewe, Maeve O'Reilly, Lourdes Martín, Pere Barba
Journal: Blood
Blood (2022) 140 (Supplement 1): 1592–1594.
https://doi.org/10.1182/blood-2022-169783
Published: 2022
Journal Articles

Improvement in Lymphoma CAR-T Outcomes over Time in the UK - CAR-T Learning Curve or Better Bridging?

Stephen Boyle, Robin Sanderson, Maeve A. O'Reilly, Tobias F. Menne, Jane Norman, Adrian Bloor, Sanne Lugthart, Sridhar Chaganti, Carlos Gonzalez-Arias, Ceri Jones, Anne-Louise Latif, Reuben Benjamin, Piers Patten, Deborah Yallop, Victoria Potter, Claire Roddie, Andrea Kuhnl
Journal: Blood
Blood (2022) 140 (Supplement 1): 4649–4651.
https://doi.org/10.1182/blood-2022-159217
Published: 2022
Journal Articles

Safety, Efficiency and Long-Term Follow-up of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Claire Roddie, Juliana Dias Alves Pinto, Maeve A O'Reilly, Marina Mitsikakou, Eftychia Charalambous, Louisa Green, Mhairi Vaughan, Giulia Agliardi, John Garcia, Evie Lewin, Mark W. Lowdell, Maria A V Marzolini, Leigh Wood, Helen Holmes, Yenting Ngai, Bilyana Popova, William Wilson, Sangeetha Kunaseelan, Victoria Spanswick, Helen Lowe, Leah Ensell, John A. Hartley, Simon Morley, David C. Linch, Adrian Bloor, David A. Irvine, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2022) 140 (Supplement 1): 7452–7453.
https://doi.org/10.1182/blood-2022-167053
Published: 2022
Journal Articles

Systematic Intention to Treat Analysis of Real-World Outcomes in Children and Young Adults Receiving Tisagenlecleucel: From Elegibility through Treatment Failure

Macarena Oporto Espuelas, Saskia Burridge, Denise Bonney, Kelly Watts, Claire Roddie, Maeve A O'Reilly, Geoff Shenton, John A Snowden, Caroline Furness, Katarzyna Aleksandra Aleksandra Jalowiec, Lorna Neill, Katherine Clesham, Emma Nicholson, Anna Castleton, Amit Patel, Caroline Besley, Robert F Wynn, Ajay Vora, David I. Marks, Lindsay George, Ben Uttenthal, Sridhar Chaganti, Michelle Cummins, Persis J Amrolia, Rachael E Hough, Sara Ghorashian
Journal: Blood
Blood (2022) 140 (Supplement 1): 2408–2410.
https://doi.org/10.1182/blood-2022-162863
Published: 2022