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Deborah Yallop
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Journal Articles

Universal base-edited CAR7 T cells for T-cell acute lymphoblastic leukemia

Free
Robert Chiesa, Christos Georgiadis, Hebatalla Rashed, Prue Hardefeldt, Roland Preece, Jan Chu, Jemma Selvage, Avijeet Mishra, Batoul Ahmed, Stuart Adams, Rebecca Thomas, Kimberly Gilmour, Deborah Yallop, David O'Connor, Waseem Qasim
Journal: Blood
Blood (2025) 146 (Supplement 1): 1041.
https://doi.org/10.1182/blood-2025-1041
Published: 2025
Journal Articles

Chimeric antigen receptor (CAR) T-cell persistence at month 3 predicts clinical outcomes in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) treated with obecabtagene autoleucel (obe-cel)

Free
Claire Roddie, Jae Park, Eleni Tholouli, Karamjeet Sandhu, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Deborah Yallop, Aaron Logan, Mehrdad Abedi, Pierre Lao-Sirieix, Ping Wang, Wolfram Brugger, Bijal Shah, Anthony Hunter, Daniel Deangelo, Elias Jabbour
Journal: Blood
Blood (2025) 146 (Supplement 1): 5118.
https://doi.org/10.1182/blood-2025-5118
Published: 2025
Journal Articles

Incorporation of 8Gy total body irradiation into reduced intensity conditioning does not improve allogeneic transplant outcomes for high-risk adult acute lymphoblastic leukemia: Results from the randomised prospective phase 2 UK multicentre ALL-RIC impact study

Free
Anna Castleton, Jak Laight, Aimee Jackson, Matthew Beasley, Jordan Evans, Patricia Diez, Adele Fielding, Andrea Hodgkinson, Stephanie Lane, David Irvine, George Mikhaeel, Nick Morley, Eduardo Olavarria, Fiona Dignan, Bela Patel Wrench, Deborah Yallop, Victoria Potter, Wendy Ingram, Ronjon Chakraverty, Charles Craddock, David Marks
Journal: Blood
Blood (2025) 146 (Supplement 1): 374.
https://doi.org/10.1182/blood-2025-374
Published: 2025
Journal Articles

An updated UK real-world analysis of factors affecting outcome following brexucabtagene autoleucel for relapsed or refractory adult acute lymphoblastic leukemia

Free
Anna Castleton, Michelle Lannon, Ned Atiyah, Alexandra Smith, Ahmed Abdulgawad, Mariam Amer, Farhan Anjum, Kathleen Cheok, David Burns, Richard Burt, Sridhar Chaganti, Johannes De Vos, Gerardo Errico, Adele Fielding, Lindsay George, Katharine Hodby, David Irvine, Shenbagaram Kasivisvanathan, Philippa Kelsey, Katja Kimberger, Andrew King, Anne-Louise Latif, David Marks, Navta Masand, Pierre McCarthy, Tobias Menne, Anthony Moorman, Nick Morley, Emma Nicholson, Maeve O'Reilly, Deborah Richardson, Huw Roddie, Clare Rowntree, Muhammad Saif, Thomas Seddon, Belen Sevillano, Kirsty Sharplin, Eleni Tholouli, Bela Patel Wrench, Deborah Yallop
Journal: Blood
Blood (2025) 146 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2025-1565
Published: 2025
Journal Articles

A UK Intention to Treat Analysis of Brexucabtagene Autoleucel for Relapsed or Refractory Adult Acute Lymphoblastic Leukaemia Following 1 Year of Therapy Access

Free
Anna Z Castleton, Michelle Lannon, Ned Atiyah, Alexandra Smith, Lindsay George, Sridhar Chaganti, Eleni Tholouli, Pakhshan Farshi, Nicholas Cunningham, Claire Arnold, Nick Morley, Philippa Kelsey, Prudence Hardefeldt, Katja Kimberger, Manish Jain, Maeve O'Reilly, Richard Burt, Tobias Menne, Ahmed Abdulgawad, Katharine Hodby, Aniruddha Dayama, David A. Irvine, Anne Louise Latif, Deborah Susan Richardson, Mariam Amer, Ram Malladi, James Aries, Seda Cakmak, Johannes De Vos, Gerardo Errico, Emma Nicholson, Kirsty Marie Sharplin, Andrew Peniket, Bela Patel Wrench, Anthony Moorman, Clare Rowntree, David Marks, Adele Fielding, Deborah Yallop
Journal: Blood
Blood (2024) 144 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2024-199287
Published: 2024
Journal Articles

Correlation between the Integrated MDS Flow Cytometry Score and Genomic Abnormalities - a Single Centre Analysis from King's College Hospital

Free
Henry Wood, Lauren Jamieson, Charles Manogaran, Katy Jones, Kar Lok Kong, Josephine Goodwin, Steve Best, Azim Mohamedali, Aytug Kizilors, Nicholas C Lea, Zoe Thorn, Frances Aldridge, Liron Barnea Slonim, Prudence Hardefeldt, Guy Hannah, Shireen Kassam, Deborah Yallop, Austin G. Kulasekararaj
Journal: Blood
Blood (2024) 144 (Supplement 1): 6751.
https://doi.org/10.1182/blood-2024-211268
Published: 2024
Journal Articles

Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Free
Claire Roddie, Karamjeet S. Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Michael R. Bishop, Jean A. Yared, Armin Ghobadi, Deborah Yallop, Aaron C. Logan, Amer M. Beitinjaneh, Jeremy M. Pantin, Martha Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla Gómez, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen M. O'Dwyer, Sameem Abedin, Hassan Alkhateeb, Bijal D. Shah, Pierre Lao-Sirieix, Gianfranco Pittari, Kapil Saxena, Yiyun Zhang, Wolfram Brugger, Martin A. Pule, Jae H. Park, Daniel J. DeAngelo, Elias Jabbour
Journal: Blood
Blood (2023) 142 (Supplement 1): 222.
https://doi.org/10.1182/blood-2023-179454
Published: 2023
Journal Articles

Improvement in Lymphoma CAR-T Outcomes over Time in the UK - CAR-T Learning Curve or Better Bridging?

Free
Stephen Boyle, Robin Sanderson, Maeve A. O'Reilly, Tobias F. Menne, Jane Norman, Adrian Bloor, Sanne Lugthart, Sridhar Chaganti, Carlos Gonzalez-Arias, Ceri Jones, Anne-Louise Latif, Reuben Benjamin, Piers Patten, Deborah Yallop, Victoria Potter, Claire Roddie, Andrea Kuhnl
Journal: Blood
Blood (2022) 140 (Supplement 1): 4649–4651.
https://doi.org/10.1182/blood-2022-159217
Published: 2022
Journal Articles

Post-Transplant Flow Cytometry MRD Predicts Relapse in a Real World AML Cohort

Free
Henry Wood, MBBS, Katy Sanchez, BSc, MSc, Victoria Potter, MBBS, BSc, FRACP, FRCPA, Austin Kulasekararaj, MD MRCP, FRCPath, Hugues de Lavallade, MD PhD, Deborah Yallop, MBBS, FRCP, FRCPath, PhD, Shireen Kassam, MBBS, FRCPath, PhD, Robin M. Ireland, MBBS, FRCP, FRCPath, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Ghulam J. Mufti, MBBS, FRCP, FRCPath, DM, Alan Dunlop, BSc, MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 4566.
https://doi.org/10.1182/blood-2019-131711
Published: 2019
Journal Articles

Preliminary Data on Safety, Cellular Kinetics and Anti-Leukemic Activity of UCART19, an Allogeneic Anti-CD19 CAR T-Cell Product, in a Pool of Adult and Pediatric Patients with High-Risk CD19+ Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Free
Reuben Benjamin, Charlotte Graham, MRCP, BSc, MBBS, Deborah Yallop, MBBS FRCP FRCPath PhD, Agnieszka Jozwik, Oana Ciocarlie, Nitin Jain, MD, Elias J. Jabbour, MD, Marcela V. Maus, MD PhD, Matthiew Frigault, MD MSc, Nicolas Boissel, MD PhD, Jerome Larghero, PharmD, PhD, Andre Baruchel, MD, Mohamad Mohty, MD PhD, Barbara De Moerloose, MD PhD, Adrian Bloor, MA MB BChir PhDFCRP FRCPath, Noelle V. Frey, MD, Amina Zinaï, MD, Svetlana Balandraud, MD, Anne Philippe, Pharm D, Sylvain Fouliard, Ludiane Gauthier, Jeanne Pauly, PharmD, Cyril Konto, MD, Candy Bermingham, PhD, Paul Veys, MD PhD, Waseem Qasim, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 896.
https://doi.org/10.1182/blood-2018-99-111356
Published: 2018
Journal Articles

Prognostic and Predictive Impact of Small PNH Clones in a Large Cohort of Patients with Myelodysplastic Syndromes and Aplastic Anemia: A Single-Center Experience

Free
Bruno Fattizzo, MD, Alan Dunlop, Robin M. Ireland, FRCP, Shireen Kassam, MD, Dario Consonni, MD, Deborah Yallop, MBBS FRCP FRCPath PhD, Ghulam J. Mufti, Judith Marsh, Alberto Zanella, MD, Wilma Barcellini, MD, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 3870.
https://doi.org/10.1182/blood-2018-99-116772
Published: 2018
Journal Articles

Real-World Outcomes of Older Patients with Primary Central Nervous System Lymphoma (PCNSL): Methotrexate Dose Intensity and Combination with Cytarabine Correlate with Response and Survival

Free
Nicolas Martinez-Calle, MD #, Edward Poynton, Alia Alchawaf, MD, Shireen Kassam, MD, Matthew Horan, MD, Mark Rafferty, MBBS, BSc, Phillipa Kelsey, MD, Gemma Scott, MD, Stephanie Bruce, MD, Hannah Buckley, MD, Sophie Jones, MD, Yeong Jer Lim, MD, Ngu Loretta, MD, David Lewis, MD, Thankamma Ajithkumar, MD, Dominic J. Culligan, Clare Rowntree, MD, Josh Wright, MD, Pamela McKay, MD, Samih Fourali, MD, Toby A. Eyre, Jeffrey Smith, MD, Wendy Osborne, MD, Deborah Yallop, MBBS FRCP FRCPath PhD, Kim Linton, MBChB PhD, Christopher P. Fox, MD PhD, Kate Cwynarski, MD PhD # (#Shared authorship)
Journal: Blood
Blood (2018) 132 (Supplement 1): 572.
https://doi.org/10.1182/blood-2018-99-111901
Published: 2018
Journal Articles

Induction Chemo-Immunotherapy with the Matrix Regimen in Patients with Newly Diagnosed PCNSL - a Multicenter Retrospective Analysis on Feasibility and Effectiveness in Routine Clinical Practice

Free
Elisabeth Schorb, MD, Chris P Fox, Benjamin Kasenda, MDPhD, Teresa Calimeri, MDPhD, Kim Linton, MBChB PhD, Jeffery Smith, MBChB BMedSci MRCP FRCPath, Slavisa Ninkovic, MBBS FRACP FRCPA, Deborah Yallop, MBBS FRCP FRCPath PhD, Hans-Guido Holl, MD, Alberto Fabbri, MD, Thomas E C Cummin, MRCP MBBCh BSc, Gerald Illerhaus, MD, Kate Cwynarski, PhDMD, Andrés J M Ferreri, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 376.
https://doi.org/10.1182/blood.V130.Suppl_1.376.376
Published: 2017
Journal Articles

Preliminary Results of UCART19, an Allogeneic Anti-CD19 CAR T-Cell Product, in a First-in-Human Trial (CALM) in Adult Patients with CD19 + Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Free
Charlotte Graham, MRCP, BSc, MBBS, Deborah Yallop, MBBS FRCP FRCPath PhD, Agnieszka Jozwik, Piers Patten, BSc, MRCP, MRCPath, PhD, Alan Dunlop, Rose Ellard, Orla Stewart, Victoria Potter, Victoria Metaxa, Shireen Kassam, Farzin Farzaneh, PhD, Stephen Devereux, FRCP, FRCPath, PhD, Antonio Pagliuca, MD, Amina Zinai, MD, Florence Binlich, MD, Sandra Dupouy, Pharm.D, PhD, Anne Philippe, Svetlana Balandraud, MD, Frédéric Dubois, Cyril Konto, MD, Premal Patel, MD PhD BSPharm, Ghulam Mufti, DM, FRCP, FRCPath, Reuben Benjamin
Journal: Blood
Blood (2017) 130 (Supplement 1): 887.
https://doi.org/10.1182/blood.V130.Suppl_1.887.887
Published: 2017
Journal Articles

Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration

Free
Marta Pasikowska, Elisabeth Walsby, Benedetta Apollonio, Kirsty Cuthill, Elizabeth Phillips, Eve Coulter, Maria Serena Longhi, Yun Ma, Deborah Yallop, Linda D. Barber, Piers Patten, Chris Fegan, Alan G. Ramsay, Chris Pepper, Stephen Devereux, Andrea G. S. Buggins
Journal: Blood
Blood (2016) 128 (4): 563–573.
https://doi.org/10.1182/blood-2016-01-683128
Published: 2016
Includes: Supplemental data
Journal Articles

Multiparameter Microscopy Analysis of the Follicular Lymphoma Microenvironment and Normal Germinal Centers: In Vivo evidence That Follicular Helper T Cells Form Synapses with Neoplastic B Cells and Are Associated with Proliferation and Expression of Activation Induced Cytidine Deaminase

Free
William M Townsend, MRCP, Robert Marcus, MB, FRCP, FRCPath, Jon Salisbury, Deborah Yallop, MB, BS, BSc.(hons), MRCP, FRCPath, Piers EM Patten, BSc, MRCP, FRCPath, PhD, Andrea GS Buggins, PhD, Stephen Devereux, MD PhD FRCPath
Journal: Blood
Blood (2014) 124 (21): 144.
https://doi.org/10.1182/blood.V124.21.144.144
Published: 2014
Journal Articles

Autologous Stem Cell Transplantation Achieves Long-Term Survival in a Selected CNS Lymphoma Population

Free
Anjum Bashir Khan, MBChB, MRCP, Alesia Abigael Hunt, MBChB, Victoria T Potter, MD FRCPA, FRACP, Shireen Kassam, MBBS, Deborah Yallop, MB, BS, BSc.(hons), MRCP, FRCPath, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Stephen Devereux, MD PhD FRCPath, Ghulam Mufti, MD DM, FRCP, FRCPath, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Robert E. Marcus, MBBS, FRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 1197.
https://doi.org/10.1182/blood.V124.21.1197.1197
Published: 2014
Journal Articles

Analysis Of T Cell Receptor Repertoire Reveals Evidence For Antigen-Specific Response In CLL Lymph Nodes

Free
Marta Pasikowska, Ph.D., Deborah Yallop, BSc, FRCPath, MB, BS, MRCP, William M Townsend, MRCP, Winston Vetharoy, Kirsty M Cuthill, MBBS, MRCP, Timothy Tree, PhD, Andrea GS Buggins, Ph.D., Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2013) 122 (21): 4141.
https://doi.org/10.1182/blood.V122.21.4141.4141
Published: 2013
Journal Articles

HCT-CI Is Not a Useful Predictor for Non Relapse Mortality in Older Patients (>60 years old) Receiving RIC Transplant for AML or MDS

Free
Victor Noriega, MD, Hugues de Lavallade, MD, Victoria T Potter, MBBS, FRCPA, FRACP, Pramila Krishnamurthy, Judith C. W. Marsh, Prof MD PhD, Stephen Devereux, FRCP, FRCPath, Ph.D., Robert E. Marcus, MBBS, FRCP, FRCPath, Kavita Raj, Donal McLornan, MD, PhD, Anjum Bashir Khan, MBChB, MRCP, Sangeeta Atwal, MBBS MRCP FRCPath, Robin M. Ireland, FRCP, FRCPath, Deborah Yallop, BSc, FRCPath, MB, BS, MRCP, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Ghulam J Mufti, FRCP, FRCPath, M.D.
Journal: Blood
Blood (2012) 120 (21): 4158.
https://doi.org/10.1182/blood.V120.21.4158.4158
Published: 2012
Journal Articles

Direct Evidence for a Chronic Antigen Driven T Cell Response In CLL Lymph Nodes

Free
Deborah Yallop, MB, BS, BSc.(hons), MRCP, FRCPath, Andrea GS Buggins, PhD, Chris Pepper, PhD, Stephen Devereux, FRCP, FRCPath, PhD
Journal: Blood
Blood (2010) 116 (21): 915.
https://doi.org/10.1182/blood.V116.21.915.915
Published: 2010