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Journal Articles

The MEK Inhibitor Selumetinib in Combination with Dexamethasone Leads to Responses in Adult and Pediatric Patients with Relapsed RAS-Pathway Mutated Acute Lymphoblastic Leukemia: Results of a Phase 1/2 Study

Britta Julia Vormoor, Tobias Menne, Joshua Savage, Amit Patel, Anna Castleton, Adele Kay Fielding, Donna Lancaster, Anne Louise Latif, Nick Morley, Geoff Shenton, Gareth Veal, Julie Irving, Pam Kearns, Lucinda Billingham, Josef Vormoor
Journal: Blood
Blood (2023) 142 (Supplement 1): 2874.
https://doi.org/10.1182/blood-2023-185855
Published: 2023
Journal Articles

Systematic Intention to Treat Analysis of Real-World Outcomes in Children and Young Adults Receiving Tisagenlecleucel: From Elegibility through Treatment Failure

Macarena Oporto Espuelas, Saskia Burridge, Denise Bonney, Kelly Watts, Claire Roddie, Maeve A O'Reilly, Geoff Shenton, John A Snowden, Caroline Furness, Katarzyna Aleksandra Aleksandra Jalowiec, Lorna Neill, Katherine Clesham, Emma Nicholson, Anna Castleton, Amit Patel, Caroline Besley, Robert F Wynn, Ajay Vora, David I. Marks, Lindsay George, Ben Uttenthal, Sridhar Chaganti, Michelle Cummins, Persis J Amrolia, Rachael E Hough, Sara Ghorashian
Journal: Blood
Blood (2022) 140 (Supplement 1): 2408–2410.
https://doi.org/10.1182/blood-2022-162863
Published: 2022
Journal Articles

Reduced Intensity Reinduction Followed By Blinatumomab Achieves Excellent MRD Clearance with Reduced Toxicity and Facilitates Timely Transplant in Children and Young People with Relapsed B-Precursor Acute Lymphoblastic Leukemia

Angus Hodder, Avijeet K Mishra, Katherine Clesham, Susan Baird, Kaljit Bhuller, Ismail Bisho, Denise Bonney, Anna Castleton, Michelle Cummins, Emmy Dickens, Lindsay George, Sara Ghorashian, Brenda Gibson, Chris Hasley, Nicholas Heaney, Rachael E Hough, Danielle Ingham, Galina Jigoulina, Katherine Lindsay, Donna Lancaster, Majid Madni, Andrea Malone, Bethany Mitchell, Anthony V. Moorman, John Moppett, Vanessa McLelland, Jayashree Motwani, Emma Nicholson, Caroline Osborne, Katharine Patrick, Lamia Samrin, Sanjay Tewari, Indu Rakesh Thakur, Sujith Samarasinghe, Ajay Vora, David O'Connor
Journal: Blood
Blood (2022) 140 (Supplement 1): 3268–3270.
https://doi.org/10.1182/blood-2022-162565
Published: 2022
Journal Articles

Use of Cryopreserved Allogeneic PBSC Results in Delayed Engraftment and Increased Incidence of Poor Graft Function

Samar Kulkarni, John Murray, James Clarke, Mike Dennis, Amit Patel, Anna Castleton, James Cavet, Angela Leather, Lyndsey Ashton, Diane Sweeney, Joanna Tomlins, Adrian Bloor, Rita Angelica, Mark Williams
Journal: Blood
Blood (2021) 138 (Supplement 1): 1778.
https://doi.org/10.1182/blood-2021-154199
Published: 2021
Journal Articles

Second Malignant Neoplasms (SMN) in Myeloma Patients Post Stem Cell Transplant (SCT)

Samar Kulkarni, John Murray, Jim Cavet, Mike Dennis, Adrian Bloor, Amit Patel, Anna Castleton, Joanna Tomlins
Journal: Blood
Blood (2021) 138 (Supplement 1): 1839.
https://doi.org/10.1182/blood-2021-154366
Published: 2021
Journal Articles

Intention to Treat Analysis of Real-World Outcomes Following Tisgenlecleucel Therapy for Pediatric and Young Adult ALL through a National Access Programme

Sara Ghorashian, FRCPath, PhD, Caroline Furness, Michelle Cummins, John A Snowden, BSc (Hons), MBChB, MD FRCP, FRCPath, Maeve A O'Reilly, MBBCHBAO, Claire Roddie, PhD MD, Lorna Neill, Emma Nicholson, Caroline Besley, MBBChir, MRCPath, MRCP, Sridhar Chaganti, MDPhDMRCP,FRCPath, John Gillson, MD, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Anna Castleton, FRCPath, Amit Patel, MBBS,PhDFRCPath,MRCP, Peter Clark, MA MDFRCP, Robert Fernley, Robert Wynn, MD, Ajay Vora, MD, David I. Marks, MB, MS, FRACP, PhD FRCPath, Geoff Shenton, Persis J Amrolia, FRCP, FRCPath, PhD, Denise Bonney, Rachael E Hough, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-138438
Published: 2020
Journal Articles

Post Allograft Rituximab Responsive Cytopenia (RRC)

Samar Kulkarni, MD, John Murray, RGN, MSc, David Kaye, MSc, Michael Dennis, FRCPath, Anna Castleton, FRCPath, Mohd K Mamat, MRCP, James Cavet, Daniel Wiseman, FRCPath, Tim Somervaille, FRCPath, Sven Sommerfeld, MRCP, Richard Chasty, FRCPath, Adrian Bloor, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 5645.
https://doi.org/10.1182/blood-2019-132214
Published: 2019
Journal Articles

Human mesenchymal stromal cells deliver systemic oncolytic measles virus to treat acute lymphoblastic leukemia in the presence of humoral immunity

Anna Castleton, Aditi Dey, Brendan Beaton, Bella Patel, Anne Aucher, Daniel M. Davis, Adele K. Fielding
Journal: Blood
Blood (2014) 123 (9): 1327–1335.
https://doi.org/10.1182/blood-2013-09-528851
Published: 2014
Includes: Multimedia, Supplemental data
Journal Articles

Donor Derived Acute Myeloid Leukaemia Following Allogeneic Cord Blood Transplantation: A Potential Role for RUNX1 and Down Syndrome Critical Region (DSCR) Genes.

Anna Castleton, Anastasios Chanalaris, Julie Howard-Reeves, Diana Brazma, Julie Glanville, Dean Nizetic, Ronjon Chakraverty, Elisabeth Nacheva
Journal: Blood
Blood (2009) 114 (22): 4300.
https://doi.org/10.1182/blood.V114.22.4300.4300
Published: 2009
Journal Articles

Female Gonadal Function Following Reduced Intensity Conditioning (RIC) Allogeneic Bone Marrow Transplantation for Haematological Malignancies.

Chara Kyriakou, MD, Melanie Davies, MD, Ratna Chatterjee, MD, PhD, Anna Castleton, MD, Kim Roberts, Andy Peniket, MD,PhD, Stephen Mackinnon, MD, Panagiotis D. Kottaridis, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 3372.
https://doi.org/10.1182/blood.V108.11.3372.3372
Published: 2006