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Journal Articles

Mitochondrial dsRNA from B-Precursor Acute Lymphoblastic Leukemia Cells Induce Formation of Cancer Associated Fibroblast in the Bone Marrow Leading to Formation of a Chemoprotective Bone Marrow Niche

Aditi Dey, Richard Burt, Emily Annie Cutler, Hermione Elsie Allen, Jenny Chatzigerou, Rodothea Amerikanou, Samantha Atkinson, Ashish Dhir, Kristina Kirschner, Adele Kay Fielding
Journal: Blood
Blood (2023) 142 (Supplement 1): 4073.
https://doi.org/10.1182/blood-2023-178759
Published: 2023
Journal Articles

The Role of Mitochondrial RNA from B-Precursor Acute Lymphoblastic Leukaemia Cells in Generating a Chemoprotective Bone Marrow Niche

Aditi Dey, Richard J. Burt, Emily A. Cutler, Hermione E. Allen, Ashish Dhir, Kristina Kirschner, Adele K. Fielding
Journal: Blood
Blood (2022) 140 (Supplement 1): 2895–2896.
https://doi.org/10.1182/blood-2022-162293
Published: 2022
Journal Articles

Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress

Richard Burt, Aditi Dey, Sarah Aref, Melanie Aguiar, Ayse Akarca, Katharine Bailey, William Day, Steven Hooper, Amy Kirkwood, Kristina Kirschner, Soo-Wah Lee, Cristina Lo Celso, Jiten Manji, Marc R. Mansour, Teresa Marafioti, Rachel J. Mitchell, Robert C. Muirhead, Kenton Cheuk Yan Ng, Constandina Pospori, Ignazio Puccio, Krisztina Zuborne-Alapi, Erik Sahai, Adele K. Fielding
Journal: Blood
Blood (2019) 134 (17): 1415–1429.
https://doi.org/10.1182/blood.2019001398
Published: 2019
Includes: Supplemental data
Journal Articles

Commonly Used Chemotherapy Drugs Differentially Determine Microenvironment-Mediated Protection, Via Mitochondrial Transfer, to B-Precursor Acute Lymphoblastic Leukaemia Cells

Richard J Burt, MBBS, Aditi Dey, PhD, Kenton Cheuk Yan Ng, BSc, Erik Sahai, PhD, Adele K Fielding, MBBS, PhD FRCP, FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 2690.
https://doi.org/10.1182/blood-2018-99-113370
Published: 2018
Journal Articles

The Relevance of CD20 Targeting of Oncolytic Measles Virus in the Treatment of Adult Acute Lymphoblastic Leukemia

Katharine E Bailey, MBBS, FRCPath, MA, MRCP, Sarah Aref, MSc, Aditi Dey, PhD, Rachel J Mitchell, MSc, Richard J Burt, MBBS, Naughton J Thomas, BSc, Dina Ahmed Said Aly Okasha, MBBS, MSc, Krisztina Zuborne Alapi, MSc, Adele K Fielding, MBBS,PhDFRCP,FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 3891.
https://doi.org/10.1182/blood.V130.Suppl_1.3891.3891
Published: 2017
Journal Articles

Acute Lymphoblastic Leukaemia (ALL) Cells and Commonly-Used Chemotherapy Drugs Can Induce Bone Marrow-Derived Mesenchymal Stromal Cells to Become Cancer Associated Fibroblasts (CAF), Leading to Enhanced ALL Proliferation and Treatment Resistance

Richard J Burt, MBBS, Aditi Dey, PhD, Kenton Cheuk Yan Ng, BSc, Bingjie Liu, MSc, Teresa Marafioti, MD, Erik Sahai, PhD, Adele K Fielding, MBBS,PhDFRCP,FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 1165.
https://doi.org/10.1182/blood.V130.Suppl_1.1165.1165
Published: 2017
Journal Articles

Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology

Bella Patel, Aditi Dey, Anna Z. Castleton, Claire Schwab, Edward Samuel, Janani Sivakumaran, Brendan Beaton, Nahid Zareian, Christie Yu Zhang, Lena Rai, Tariq Enver, Anthony V. Moorman, Adele K. Fielding
Journal: Blood
Blood (2014) 124 (1): 96–105.
https://doi.org/10.1182/blood-2014-01-549352
Published: 2014
Includes: Supplemental data
Journal Articles

Human mesenchymal stromal cells deliver systemic oncolytic measles virus to treat acute lymphoblastic leukemia in the presence of humoral immunity

Anna Castleton, Aditi Dey, Brendan Beaton, Bella Patel, Anne Aucher, Daniel M. Davis, Adele K. Fielding
Journal: Blood
Blood (2014) 123 (9): 1327–1335.
https://doi.org/10.1182/blood-2013-09-528851
Published: 2014
Includes: Multimedia, Supplemental data
Journal Articles

Feasibility Of Pegylated-Asparaginase (PEG-ASP) During Induction In Adults With Acute Lymphoblastic Leukaemia (ALL): Results From The UK Phase 3 Multicentre Trial UKALL 14

Bella Patel, MB, BS, MD, A Kirkwood, Aditi Dey, Clare Rowntree, Andrew McMillan, FRCP, FRCPath, PhD, David Marks, MD, PhD, Tobias Menne, Paul Smith, PhD, Simon Purnell, Lynda Micklewright, Adele K Fielding, MB, BS, PhD
Journal: Blood
Blood (2013) 122 (21): 3900.
https://doi.org/10.1182/blood.V122.21.3900.3900
Published: 2013
Journal Articles

An Optimised In Vivo Modelling System For Adult Acute Lympoblastic Leukaemia (ALL) Enables Sensitive Detection Of Leukaemia Initiating Cells (LIC) and Drug Resistant Clones

Bella Patel, MB, BS, MD FRCPath, Aditi Dey, Anna Z Castleton, MB, BS, MRCP, FRCPath, Claire Schwab, Brendan Beaton, Nahid Zareian, Christie Zhang, Anthony V Moorman, PhD, Adele Fielding
Journal: Blood
Blood (2013) 122 (21): 2641.
https://doi.org/10.1182/blood.V122.21.2641.2641
Published: 2013