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Journal Articles

A UK Intention to Treat Analysis of Brexucabtagene Autoleucel for Relapsed or Refractory Adult Acute Lymphoblastic Leukaemia Following 1 Year of Therapy Access

Anna Z Castleton, Michelle Lannon, Ned Atiyah, Alexandra Smith, Lindsay George, Sridhar Chaganti, Eleni Tholouli, Pakhshan Farshi, Nicholas Cunningham, Claire Arnold, Nick Morley, Philippa Kelsey, Prudence Hardefeldt, Katja Kimberger, Manish Jain, Maeve O'Reilly, Richard Burt, Tobias Menne, Ahmed Abdulgawad, Katharine Hodby, Aniruddha Dayama, David A. Irvine, Anne Louise Latif, Deborah Susan Richardson, Mariam Amer, Ram Malladi, James Aries, Seda Cakmak, Johannes De Vos, Gerardo Errico, Emma Nicholson, Kirsty Marie Sharplin, Andrew Peniket, Bela Patel Wrench, Anthony Moorman, Clare Rowntree, David Marks, Adele Fielding, Deborah Yallop
Journal: Blood
Blood (2024) 144 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2024-199287
Published: 2024
Journal Articles

Diagnosis, prognostic factors, and assessment of ALL in adults: 2024 ELN recommendations from a European expert panel

Nicola Gökbuget, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan
Journal: Blood
Blood (2024) 143 (19): 1891–1902.
https://doi.org/10.1182/blood.2023020794
Published: 2024
Includes: Supplemental data
Journal Articles

Management of ALL in adults: 2024 ELN recommendations from a European expert panel

Nicola Gökbuget, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan
Journal: Blood
Blood (2024) 143 (19): 1903–1930.
https://doi.org/10.1182/blood.2023023568
Published: 2024
Includes: Supplemental data
Journal Articles

Successful outcome following allogeneic hematopoietic stem cell transplantation in adults with primary immunodeficiency

Clinical Trials & Observations
Thomas A. Fox, Ronjon Chakraverty, Siobhan Burns, Benjamin Carpenter, Kirsty Thomson, David Lowe, Adele Fielding, Karl Peggs, Panagiotis Kottaridis, Benjamin Uttenthal, Venetia Bigley, Matthew Buckland, Victoria Grandage, Shari Denovan, Sarah Grace, Julia Dahlstrom, Sarita Workman, Andrew Symes, Stephen Mackinnon, Rachael Hough, Emma Morris
Journal: Blood
Blood (2018) 131 (8): 917–931.
https://doi.org/10.1182/blood-2017-09-807487
Published: 2018
Journal Articles

Delays in Start of Intensification Therapy Are Common for Adults with Acute Lymphoblastic Leukemia, and Are Associated with Decreased Survival in Patients Who Undergo Allogeneic Stem Cell Transplant (SCT)

Anita J. Kumar, MDMS, Phyllis A. Gimotty, PhD, Joel Gelfand, MDMS, Georgina Buck, Jacob M. Rowe, MD, Anthony H Goldstone, MD, Adele Fielding, MB BS, PhD, David I Marks, Mark Litzow, Elisabeth Paietta, PhD, Hillard M. Lazarus, Martin S. Tallman, MD, Selina M. Luger, MD, Alison W. Loren, MDMS
Journal: Blood
Blood (2014) 124 (21): 208.
https://doi.org/10.1182/blood.V124.21.208.208
Published: 2014
Journal Articles

Barriers To Clinical Trial Enrolment For Teenagers and Young Adults With Acute Lymphoblastic Leukaemia: The Impact of Age Eligibility Criteria

Lorna Anne Fern, BSc, MSc, PhD, Clare Rowntree, PhD, Rachael E Hough, MD, Ajay J Vora, Adele Fielding, MB BS, PhD, Chris Mitchell, Nicholas Goulden, Robert Alston, PhD, Jillian Birch, MD, O'hara Catherine, PhD, Jeremy Whelan, MD FRCP
Journal: Blood
Blood (2013) 122 (21): 1401.
https://doi.org/10.1182/blood.V122.21.1401.1401
Published: 2013
Journal Articles

Evaluation Of IKZF1 Δ4-7 Deletion As a Suitable Marker For Minimal Residual Disease Monitoring; A Study Of 161 Consecutive Acute Lymphoblastic Leukaemia (ALL) Patients On The On-Going UKALL14 Trial

Nahid Zareian, Bella Patel, MBBS, FRCPath, Lena Rai-Shetty, PhD, Clare Rowntree, PhD, Andrew McMillan, FRCP, FRCPath, PhD, David I Marks, Tobias Menne, Paul Smith, Simon Purnell, Lynda Micklewright, Anthony V. Moorman, Adele Fielding, MB BS, PhD
Journal: Blood
Blood (2013) 122 (21): 1335.
https://doi.org/10.1182/blood.V122.21.1335.1335
Published: 2013
Journal Articles

An Optimised In Vivo Modelling System For Adult Acute Lympoblastic Leukaemia (ALL) Enables Sensitive Detection Of Leukaemia Initiating Cells (LIC) and Drug Resistant Clones

Bella Patel, MB, BS, MD FRCPath, Aditi Dey, Anna Z Castleton, MB, BS, MRCP, FRCPath, Claire Schwab, Brendan Beaton, Nahid Zareian, Christie Zhang, Anthony V Moorman, PhD, Adele Fielding
Journal: Blood
Blood (2013) 122 (21): 2641.
https://doi.org/10.1182/blood.V122.21.2641.2641
Published: 2013
Journal Articles

International Standardization of Minimal Residual Disease Assessment for in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL) Expressing m-BCR-ABL Transcripts: Updated Results of Quality Control Procedures by the EWALL and ESG-MRD-ALL Consortia

Heike Pfeifer, MD, Giovanni Cazzaniga, Orietta Spinelli, Jean-Michel Cayuela, Hélène Cavé, Peter Vandenberghe, MD, PhD, Carmen Chillon, Tomasz Sacha, MD, Sandrine Hayette, PhD, Silja Roettgers, PhD, Thomas Lion, MD, PhD, Professor, Letizia Foroni, MD PhD, Vincent H.J. van der Velden, PhD, Jan Zuna, Monica Hermanson, PhD, Martin Christian Mueller, MD, Thoralf Lange, Miroslaw Majewski, MD, Israel Bendit, MD, Fabrizio Pane, Ilaria Iacobucci, PhD, Veli Kairisto, MD, PhD, Christa Homburg, Smadar Avigad, Eng Juh Allen Yeoh, Beat Schäfer, Adele Fielding, Loredana Elia, Katarzyna Borg, Eric Delabesse, Susanne Schnittger, PhD, Sandra Markovic, Volker Werner, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Jacques J.M. van Dongen, PhD, Oliver G. Ottmann, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2535.
https://doi.org/10.1182/blood.V118.21.2535.2535
Published: 2011
Journal Articles

Positive Pre-Transplantation [18-F] FDG-PET Is Not a Barrier to Successful Allograft Outcomes in Chemosensitive Hodgkin Lymphoma

Karl S Peggs, Irfan Kayani, Kirsty Thomson, Emma Morris, MD, Panagiotis Kottaridis, Kirit M Ardeshna, MD, Adele Fielding, Rachael Hough, Anthony H Goldstone, MD, Ronjon Chakraverty, David C Linch, MD FMedSci, Stephen Mackinnon
Journal: Blood
Blood (2011) 118 (21): 2016.
https://doi.org/10.1182/blood.V118.21.2016.2016
Published: 2011
Journal Articles

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL): Results From the International MRC/ECOG Trial

Jonathan I Sive, MBChB, Georgina Buck, Adele Fielding, MBBS, PhD, FRCPath, FRCP, Hillard M. Lazarus, MD, FACP, Mark R. Litzow, MD, Selina Luger, MD, David I. Marks, MBBS, PHD, Andrew McMillan, FRCP, FRCPath, PhD, Susan M Richards, PhD, Jacob M. Rowe, Martin S. Tallman, MD, Anthony H. Goldstone, FRCP, FRCPath
Journal: Blood
Blood (2010) 116 (21): 493.
https://doi.org/10.1182/blood.V116.21.493.493
Published: 2010
Journal Articles

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia (B-ALL) Patients (pts) From the International UKALLXII/E2993 Trial: No Difference In Results Between B Cell Immunophenotypic Subgroups

Mark R. Litzow, MD, Georgina Buck, Gordon Dewald, Adele Fielding, MBBS, PhD, FRCPath, FRCP, Rhett Ketterling, Hillard M. Lazarus, MD, FACP, Selina Luger, MD, David I. Marks, MBBS, PHD, Andrew McMillan, FRCP, FRCPath, PhD, Anthony V. Moorman, PhD, Elisabeth Paietta, PhD, Susan M Richards, PhD, Jacob M. Rowe, Martin S. Tallman, MD, Anthony H. Goldstone, FRCP, FRCPath
Journal: Blood
Blood (2010) 116 (21): 524.
https://doi.org/10.1182/blood.V116.21.524.524
Published: 2010
Journal Articles

Vaccine Measles Virus Has Therapeutic Potential In B Cell Malignancy.

Bella Patel, MBBS, FRCPath, Dey Aditi, Ehsan Ghorani, Yogesh Malam, Steele Andy, R. Wickremasinghe, Rai Lena, Adele Fielding, MBBS, PhD, FRCPath, FRCP
Journal: Blood
Blood (2010) 116 (21): 3757.
https://doi.org/10.1182/blood.V116.21.3757.3757
Published: 2010
Journal Articles

Impact of in vivo alemtuzumab dose before reduced intensity conditioning and HLA-identical sibling stem cell transplantation: pharmacokinetics, GVHD, and immune reconstitution

Clinical Trials & Observations
Ronjon Chakraverty, Guillermo Orti, Michael Roughton, Jun Shen, Adele Fielding, Panagiotis Kottaridis, Donald Milligan, Matthew Collin, Charles Crawley, Peter Johnson, Andrew Clark, Anne Parker, Adrian Bloor, Ruth Pettengell, John Snowden, Andrew Pettitt, Richard Clark, Geoff Hale, Karl Peggs, Kirsty Thomson, Emma Morris, Stephen Mackinnon
Journal: Blood
Blood (2010) 116 (16): 3080–3088.
https://doi.org/10.1182/blood-2010-05-286856
Published: 2010
Journal Articles

In Adults with Standard-Risk Acute Lymphoblastic Leukemia (ALL) the Greatest Benefit Is Achieved from an Allogeneic Transplant in First Complete Remission (CR) and an Autologous Transplant Is Less Effective Than Conventional Consolidation/Maintenance Chemotherapy: Final Results of the International ALL Trial (MRC UKALL XII/ECOG E2993).

Jacob M. Rowe, MD, Georgina Buck, PhD, Adele Fielding, MD, Martin S. Tallman, MD, Alan K. Burnett, MD, Raj Chopra, MD, Peter H. Wiernik, MD, Susan M. Richards, PhD, Hillard M. Lazarus, MD, Letizia Foroni, MD, Elisabeth Paietta, PhD, Mark R. Litzow, MD, David Marks, MD, Jill Durrant, MD, Anthony H. Goldstone, MD
Journal: Blood
Blood (2006) 108 (11): 2.
https://doi.org/10.1182/blood.V108.11.2.2
Published: 2006
Journal Articles

Karyotype Is an Independent Prognostic Factor in Adult Acute Lymphoblastic Leukaemia (ALL): Analysis of Cytogenetic Data from 1,235 Patients on the Medical Research Council (MRC) UKALLXII /Eastern Cooperative Oncology Group (ECOG) 2993 Trial.

Anthony V. Moorman, Christine J. Harrison, Sue M. Richards, Adele Fielding, Martin S. Tallman, Mark R. Litzow, Jacob M. Rowe, Anthony H. Goldstone, Gordon W. Dewald
Journal: Blood
Blood (2005) 106 (11): 331.
https://doi.org/10.1182/blood.V106.11.331.331
Published: 2005
Journal Articles

The Impact of Imatinib Therapy on Adult Philadelphia Positive Acute Lymphoblastic Leukaemia (ALL): Early Results from the UKALL12/ECOG 2993 Study.

Bella Patel, MBBS, BSc, Anthony H. Goldstone, MBBS, Philip Ross, BSc Pharmacology, Sue Richards, PhD, Letizia Foroni, MBBS, PhD, R. Chopra, MBBS, PhD, Adele Fielding, MBBS, PhD
Journal: Blood
Blood (2005) 106 (11): 1839.
https://doi.org/10.1182/blood.V106.11.1839.1839
Published: 2005
Journal Articles

Molecular Monitoring of Residual Disease (MRD) during Induction and Intensification Phases in Low Risk Adult B Cell ALL Treated According to the MRC UKALL12 Protocol.

Letizia Foroni, MD, PhD, Wayne Mitchell, PhD, Lena J. Rai, Anouska Casanova, Gareth Gerrard, Bella Patel, Sue Richards, Adele Fielding, Anthony H. Goldstone
Journal: Blood
Blood (2005) 106 (11): 1466.
https://doi.org/10.1182/blood.V106.11.1466.1466
Published: 2005
Journal Articles

The Value of Molecular Monitoring for Residual Disease (MRD) in Early Morphological Remitters among Adults Diagnosed with B Cell ALL and Treated According to the MRC UKALL12 Protocol.

Letizia Foroni, MD, PhD, Wayne Mitchell, PhD, Lena J. Rai, Sue Richards, Adele Fielding, Anthony H. Goldstone
Journal: Blood
Blood (2005) 106 (11): 1467.
https://doi.org/10.1182/blood.V106.11.1467.1467
Published: 2005
Journal Articles

Value of Molecular Monitoring for Minimal Residual Disease Preceding Autologous SCT Following Diagnosis of B Cell Acute Lymphoblastic Leukemia in Patients Treated with the MRC UKALL12 Protocol.

Letizia Foroni, MD, PhD, Wayne Mitchell, PhD, Lena J. Rai, Anouska Casanova, Bella Patel, MD, Sue Richards, Adele Fielding, MD, Anthony H. Goldstone
Journal: Blood
Blood (2005) 106 (11): 1468.
https://doi.org/10.1182/blood.V106.11.1468.1468
Published: 2005